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All Journal Microbiology Indonesia Indonesian Journal of Urology Jurnal Berkala Epidemiologi Indonesian Journal of Tropical and Infectious Disease Belitung Nursing Journal J-Dinamika: Jurnal Pengabdian Kepada Masyarakat JURNAL KESEHATAN MERCUSUAR Majalah Biomorfologi (Biomorphology Journal) CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Jurnal Pengabdian Masyarakat dalam Kesehatan International Islamic Medical Journal Narra J Jurnal Ilmiah Kesehatan (JIKA) Makara Journal of Health Research
Juniastuti Juniastuti
Department Of Microbiology, Medical Faculty, Universitas Airlangga, Surabaya Indonesia-Japan Collaborative Research Center For Emerging And Re-emerging Infectious Diseases Institute Of Tropical Disease, Universitas Airlangga, Surabaya, Indonesia
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HEPATITIS B SEROLOGY PROFILES ON CHILDREN AGED 1–13 YEARS OLD IN SUMENEP, MADURA Putera, Edward M; Marcia, Dian; Firdarini, Itja; Amin, Mochamad; Juniastuti, Juniastuti; Purwono, Priyo B; Utsumi, Takako; Lusida, Maria I
Indonesian Journal of Tropical and Infectious Disease Vol 3, No 2 (2012)
Publisher : Institute of Topical Disease

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (96.893 KB)

Abstract

Background: Hepatitis B virus (HBV) which was acquired during perinatal or childhood would promote hepatocellular carcinoma with even higher percentage than that which was acquired during adult age. That is why HBV represents a serious public health threat for children. HBV vaccination has been integrated into national expanded programme on immunization (EPI) since 1997. The aimof they study is to investigate the prevalence of HBV among children who were born after 1997 in Sumenep. Material and Methods: a total of 102 children who were born after 1997 were enrolled in this study. All children were admitted in the Emergency Room and Pediatric Ward of dr. H. Moh Anwar General Hospital for some reasons. Written informed consents were obtained from parents/guardians of all the children. Study protocol was reviewed and approved by the Ethics Committees. All of these cases were examined for hepatitis B surface antigen (HBsAg), antibody to HBsAg (Anti-HBs), and antibody to hepatitis B core antigen (Anti-HBc). Result and Discussion: Overall, 6 (5.88%) of 102 samples were positive for HBsAg, 51 (50.00%) of 102 samples were positive for anti-HBs, and 49 (48.04%) of 102 samples were positive for anti-HBc. All the children were born after 1997. Conclusion: HBsAg rate is still high even after universal vaccination program, acquired protective antibodies against hepatitis B surface antigen were sufficient, but there is a suspicion for occult hepatitis B infections (OBI). A further study to confirm OBI is needed.
The Prevalence of Human Immunodefiency Virus-1 (HIV-1) Subtypes and Transmission Method among HIV/AIDS Infection Patient in Tulungagung, East Java Indonesia Ardianto, Achmad; Khairunisa, Siti Qamariyah; Kotaki, Tomohiro; Witaningrum, Adiana Mutamsari; Qushay, M.; Juniastuti, Juniastuti; Rahayu, Retno Pudji; Widiyanti, Prihartini; Utomo, Budi; Lusida, Maria Inge; Nasronudin, Nasronudin
Indonesian Journal of Tropical and Infectious Disease Vol 5, No 5 (2015)
Publisher : Institute of Topical Disease

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Abstract

The rapid epidemic growth of HIV is continuing in Indonesia. There are some factors which have influenced the spreading of this epidemic in Indonesia, such as the poor awareness to avoid unsafe free sex attitude and the sharing of needles and syringes among intravenous drug users (IDUs). The sexual transmission of HIV has also apparently increased in Tulungagung. Commercial sex workers play a significant role in the spread of HIV in Tulungagung. People in Tulungagung have worked at other countries as Indonesian migrants. This condition can cause the increase number of HIV-1 case and the possibility of genetic variation (subtype) HIV-1 in Tulungagung. This research is aimed to analyze the subtype and to determine estimation of transmission mode on infected patient of HIV-1 and AIDS who came to Seruni clinic Dr. Iskak hospital in Tulungagung. 40 HIV?AIDSpatients were interviewed to determine the subtype and the transmission mode. The results showed that 14 of 40 plasma samples (35%) were successfully to amplified and sequenced. OverallCRF01-AE wereidentified as predominant subtype among HIV/AIDS patients in Tulungagung. Based on individual information, 31 of 40 subjects (77%) were heterosexual transmission.
CORRELATION OF ROUTINE URINE CULTURE AND STONE CULTURE TO POST-OPERATIVE SIRS Indrawan, Taufik; Hardjowijoto, Sunaryo; Soebadi, Doddy M.; Juniastuti, Juniastuti; Budiono, Budiono
Indonesian Journal of Urology Vol 21 No 1 (2014)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v21i1.21

Abstract

Objective: This study evaluated the correlation between preoperative urine culture and intraoperative stone culture and the impact of stone culture findings on post-operative systemic inflammatory response syndrome. Material & Method:Patients with kidney stones who underwent percutaneous nephrolithotomy (PCNL) from February to May 2012 were prospectively analyzed. A pre-operative urine culture was obtained in the morning before the operation, fragmented stone collected were cultured in Departement of Microbiology. Patients were monitored closely in the postoperative period for signs of systemic inflammatory response syndrome (SIRS). Results:A total of 33 patients underwent PCNL and examined for urine cultures, stone culture and postoperative SIRS, 15 (45.45%) patients with positive urine culture, 18 patients (54.54%) with positive stone culture but only 1 patient (3.03%) had same pathogen (p = 0.629). Ten patients (55.6%) with positive stone cultures had evidence of systemic inflammatory respose syndrome postoperatively. The calculated stone culture value for sensitivity, specificity, positive predictive value and negative predictive value were 100%, 65.2%, 55.6%, and 100%. Preoperative hydronephrosis (p = 0.003) and operative time (p = 0.001) are identified as the key risk factors for SIRS after PCNL.Conclusion: Positive stone culture are better predictors for SIRS after PCNL. Stone culture examination is an essential in directing the proper antibiotic therapyin patients with SIRS after PCNL.  Keywords: Percutaneous nephrolithotomy (PCNL), urine culture, stone culture, systemic inflammatory response syndrome after PCNL.
Analyses of Precore and Core Promoter Mutations of Hepatitis B Virus in Patients with Chronic Hepatitis B in Surabaya, Indonesia . JUNIASTUTI; EDUARDUS BIMO AKSONO; TAKAKO UTSUMI; YOSHIHIKO YANO; . SOETJIPTO; YOSHITAKE HAYASHI; HAK HOTTA; FEDIK ABDUL RANTAM; HERNOMO ONTOSENO KUSUMOBROTO; MARIA INGE LUSIDA
Microbiology Indonesia Vol. 4 No. 3 (2010): December 2010
Publisher : Indonesian Society for microbiology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1048.865 KB) | DOI: 10.5454/mi.4.3.%p

Abstract

Mutations of precore (A1896) and core promoter (T1762/A1764) of hepatitis B virus can reduce HBeAg production. These mutations are frequently found in the late HBeAg seroconversion. However, it has been a controversy about the role played by precore and core promoter mutations in determining outcome of chronic hepatitis B. In the present study, the variability of precore and core promoter of hepatitis B virus were analyzed using PCR amplification and sequencing, according to the outcome (viral load and HBeAg/anti-HBe) in chronic hepatitis B patients in Surabaya. The study groups included 5 patients with uncomplicated chronic hepatitis B and 10 patients with chronic hepatitis B and liver cirrhosis in Dr. Soetomo Hospital, Surabaya. The control group included 6 blood donors obtained from Indonesia Red Cross, Surabaya. All groups were HBsAg positive. Precore mutation A1896 was predominant in all groups (60%-67% of each), together with precore variant T1858. As reported, precore variant T1858 is a prerequisite for precore A1896 and characteristic for viral genotype. Nevertheless, core promoter mutations T1762/A1764 were predominant only in LC patients (60%). All of these mutations were found mostly after HBeAg seroconversion (anti-HBe+). Of most samples with anti-HBe+, precore mutation was related with low viral load (<105 copies/mL), but core promoter mutations with high viral load (>105 copies/mL). Precore mutation A1896 was predominant in all groups, but core promoter mutations T1762/A1764 were only predominant in LC patients. The precore mutation alone is possible not critical to indicate a poor outcome, the core promoter mutations must be considered also.
Faktor Risiko Keterlambatan Perkembangan Bicara dan Bahasa pada Anak Usia 24-48 Bulan Desi Fitriani; Juniastuti; Ahmad Suryawan
JURNAL KESEHATAN MERCUSUAR Vol. 5 No. 1 (2022): JURNAL KESEHATAN MERCUSUAR
Publisher : STIKes MERCUBAKTIJAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36984/jkm.v5i1.276

Abstract

Speech and language skills are the determinants of all child development. Psychosocial factors are one of the most researched postnatal environmental factors, but most research only examines one of many psychosocial factors. In this research, 4 psychosocial factors will be researched. The purpose of this study was to determine the frequency of stimulation, quality of parent-child interaction, the intensity of the use of gadgets, and the duration of watching television as risk factors for speech and language delayed in children aged 24-48 months in Surabaya. This type of study was a case-control study in 122 children aged 24-48 months in 2 working areas of the Public Health Center in Surabaya. Data were analyzed by Chi-Square, contingency coefficient, and logistic regression test. The result showed that there was a relationship between the frequency of stimulation (p < 0.01), the quality of parent-child interaction (p < 0.01), the intensity of device use (p < 0.01), and television viewing duration (p < 0.01 ) with the risk of delayed speech and language development in children and the most dominant risk factor is the quality of parent-child interaction (OR 21,567). It can be concluded that frequency of stimulation, quality of parent-child interaction, the intensity of the use of gadgets, and duration of watching television are risk factors for delayed speech and language development in children aged 24-48 months, and the quality of parent-child interaction is the most influential risk factor. Keywords: speech and language development; children
BACTERIAL PATTERN AMONG SEPSIS PATIENTS IN INTERNAL MEDICINE INPATIENT WARD DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA Ilma Dzurriyyatan Toyyibah; Musofa Rusli; Juniastuti Juniastuti
Majalah Biomorfologi Vol. 32 No. 2 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i1.2022.52-58

Abstract

Highlights:1. Bacteria remain a major cause of bacterial sepsis.2. The most common causal agent in bacterial septicaemia was the gram-positive bacterium. Abstract: Background: Bacteria remain the primary cause of bacterial sepsis. Gram-negative bacteria are the most commonly isolated from sepsis patients. However, gram-positive bacterial infections have also increased recently. Objective: To identify the pattern of bacterial infection in sepsis patients in Internal Medicine inpatient ward Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Material and Method: This retrospective study reviewed the medical records of all sepsis patients in Internal Medicine Ward Dr. Soetomo General Academic Hospital, Surabaya, Indonesia from January 1 – December 31, 2016. All patients were divided according to bacterial species into two groups: patients with gram-positive and gram-negative infection. The collected data were statistically analyzed using SPSS ver. 16.0 to find out the frequency. Result: From 179 eligible data reviewed, there were 103 (57.5%) patients with gram-positive bacterial infection and 76 (43.5%) patients with a gram-negative bacterial infection. The major isolates of gram-positive bacteria were Staphylococcus hominins (30 isolates) and gram-negative bacteria was Escherichia coli (30 isolates), 43 isolates showed multi-drug resistant organisms; Escherichia coli ESBL 23 isolates, Klebsiella pneumoniae ESBL 3 isolates, Klebsiella oxytoca ESBL 2 isolates and Methilcillin Resistance Staphylococcus aureus 5 isolates. Conclusion: The most common causative agent in bacterial sepsis was gram-positive bacteria. The major isolated gram-positive bacteria are Staphylococcus hominis and gram-negative bacteria were Escherichia coli. The species of multi-drug resistant organisms found are Methilcillin-Resistant Staphylococcus aureus (MRSA), Escherichia coli ESBL, Klebsiella pneumonia ESBL and Klebsiella oxytoca ESBL. Among the patients with multi-drug resistant organism infection, Escherichia coli ESBL were the most prevalent one.
Diare Akut pada Balita di Puskesmas Tanah Kali Kedinding Surabaya Yunita Ratri Adhiningsih; Alpha Fardah Athiyyah; Juniastuti Juniastuti
Jurnal Ilmiah Kesehatan (JIKA) Vol. 1 No. 2 (2019): Volume 1 Nomor 2 Desember 2019
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (333.492 KB) | DOI: 10.36590/jika.v1i2.31

Abstract

Diarrhea is a disease that still be a health problem in the world, including Indonesia. The number of cases of diarrhea in children under five in East Java had increased in prevalence from 6.6% in 2013 to 10.7% in 2018. Deaths in diarrhea usually occurred as a result of severe dehydration which 70% -80% of them were children under-5 years. This study aimed to know the characteristics of children under-5 years who had acute diarrhea at Tanah Kali Kedinding Primary Health Care in September 2018 - January 2019. This type of research was a descriptive study, where the results was only a picture, using a cross-sectional approach. Statistical analysis was performed to describe the characteristics of each patient by using a frequency descriptive test. The results of this study found that in September 2018 - January 2019, of 116 children under-5 years suffering from acute diarrhea in the Tanah Kali Kedinding Health Care, Surabaya, most of them were females, within 1-2 years, had exclusive breastfeeding, had parents with the last education graduated from high school and family income under minimum of wage in Surabaya. It is hoped that this research will become a source of information for the Government and Primary Health Care to reduce the incidence of acute diarrhea.
EMPOWERMENT OF DIABETES MELLITUS PATIENT DURING COVID-19 PANDEMIC ERA THROUGH ONLINE GATHERING Nur Rochmah; Sukmawati Basuki; Fatimah Arief; Muhammad Faizi; Faisal Faisal; Juniastuti Juniastuti; Herman Kosasih
Jurnal Pengabdian Masyarakat Dalam Kesehatan Vol. 4 No. 2 (2022): OCTOBER 2022
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jpmk.v4i2.37884

Abstract

Introduction: In the COVID-19 pandemic, social restriction and lock-down policies were implemented. It has far-reaching implications in many sectors of life including health, particularly in patients with chronic diseases, one of which is Type-1 Diabetes Mellitus (T1DM). The purpose of this community service in the form of online gathering is to facilitate patients to ask questions and consult with pediatricians, due to the limitations of patients to consult directly due to the pandemic. Methods: Community service is conducted online for T1DM patients or their relatives on Sunday, September 26, 2021, from 12.00 - 13.30 WIB. The Community service was divided into several stages, including before, during, and after the online gathering.  The T1DM patients or their relatives are participants in this community services. The topic are types of Diabetes Mellitus, clinical presentation, disease progression, the diagnostic process, and its management therapy of type 1 diabetes mellitus. Results: The community service was attended by 54 parents of T1DM patient. The online gathering goes smoothly, without being constrained by something. During the online gathering, subjects actively participate in every session during the online gathering. Several questions were asked by the participants and answered well by the speakers. Conclusion: This community services activities allow participant to be able to ask question about their problem according to diabetes mellitus. Participants can consult online with pediatricians. This online gathering has a limited time, so participants can be divided into several breakout rooms with several accompanying pediatricians, so that the QnA session can be done optimally.
The Prevalence and Subtype Distribution of Hepatitis C Virus Infection among Hemodialysis Patients in a Private Hospital in Surabaya, Indonesia MOCHAMAD AMIN; JUNIASTUTI .; TAKAKO UTSUMI; YOSHIHIKO YANO; MOCHAMAD YUSUF; MOCHAMMAD THAHA; PRIYO BUDI PURWONO; RETNO HANDAJANI; SOETJIPTO .; HAK HOTTA; YOSHITAKE HAYASHI; MARIA INGE LUSIDA
Microbiology Indonesia Vol. 6 No. 4 (2012): December 2012
Publisher : Indonesian Society for microbiology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (837.539 KB) | DOI: 10.5454/mi.6.4.5

Abstract

The prevalence of hepatitis C virus (HCV) infection has been as high as approximately 80% in patients with maintenance hemodialysis in public hospitals in Indonesia. However, the prevalence in private hospitals has not been examined yet. The aim of  this study was  to  investigate  the prevalence of anti-HCV antibody and  the subtype distribution in patients with hemodialysis in a private hospital in Surabaya, Indonesia. Sera were obtained from 41 hemodialysis patients in a private hospital in Surabaya. The positive prevalence of anti-HCV antibody was carried out by  the enzyme-linked  immunosorbent assay (ELISA). Anti-HCV-positive sera were subjected  to  reverse transcription-PCR (RT-PCR) to detect HCV RNA and then direct sequencing. The HCV subtype was examined by phylogenetic analysis. Twenty five patients (61%) out of 41 were positive for anti-HCV antibody, and HCV-RNA was detected in 19 patients. The positive prevalence of anti-HCV antibody was 7.7% (one out of 13 patients) among patients who had undergone hemodialysis  for  less  than one year, whereas  it was 85.7%  (24 out of  28  patients)  among  patients who  had  undergone  hemodialysis  for  over  one  year.  Phylogenetic  analysis revealed HCV-1a  (52.6%) was  the most common  subtype,  followed by 1b  (15.8%), 1c  (15.8%), 2a  (5.3%), and 3k (5.3%). In conclusion,  the prevalence of HCV  infection among hemodialysis patients  in a private hospital was as high as  that  in general hospitals. The predominant subtype was HCV-1a, which  is  in accordance with  the previous studies  in general hospitals  in Surabaya,  Indonesia.
The potential risk components and prevention measures of the Ebola virus disease outbreak in Liberia: An in-depth interview with the health workers and stakeholders Moses Tende Stephens; Juniastuti; Sulistiawati; Peter Chilaque Dossen
Belitung Nursing Journal Vol. 10 No. 1 (2024): January - February
Publisher : Belitung Raya Foundation, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33546/bnj.3069

Abstract

Background: The Ebola virus, a highly infectious and deadly pathogen, has posed a significant public health threat in West Africa for several decades. Liberia is one of the most severely affected countries. Healthcare personnel, including nurses, are on the front lines of patient care, and their perspectives are invaluable in understanding the challenges that arise during outbreaks, especially in implementing prevention measures. Objective: This study aimed to explore the potential risk components and prevention measures of the Ebola virus disease (EVD). Methods: This study used an exploratory descriptive qualitative design. Five stakeholders, ten doctors and five nurses who had suffered from EVD during the outbreak in Liberia participated in semi-structured interviews to provide their experience and comprehensive perspectives on EVD. Data were collected from February 2022-August 2023. NVivo 12 plus was used for inductive thematic analysis. Results: Six themes and several subthemes emerged: 1) transmission modes (body contact, body fluid, sexual intercourse, traditional burial), 2) funeral attendance (traditional practices and crowded gatherings), 3) community-led prevention (promoting good hygiene practices, increasing awareness, contact tracing, and surveillance), 4) Ebola virus vaccine (false sense of security, potential side effects, and limited data), 5) challenges in implementing prevention measures (inadequate health infrastructures, difficulty of tracing infected people, lack of resources, and cultural-social barriers), 6) Liberia’s health systems (a weak, underfunded, fragile health infrastructure, lack of health facilities and shortage of health workers). Conclusion: Several potential risk components contributing to the EVD outbreak should be a public concern. Strengthening the current healthcare system supported by local community and international aid providers (multidisciplinary teams) is needed to anticipate behavioral problems and to improve the efficacy of the prevention measures appropriate to the conditions in Liberia. Accordingly, the nurses’ compliance with the recommended prevention practices is necessary.
Co-Authors A.A. Ketut Agung Cahyawan W Achmad Ardianto, Achmad Adhiningsih, Yunita Ratri Adiana Mutamsari Witaningrum Adnyana , I Made Dwi Mertha Ahmad Suryawan Al Karina, Citra Alfaray, Ricky I. Alpha Fardah Athiyyah Ana Bilah, Aisah Nur Andy Darma Annisa Fira Salsabila Asmarawati, Tri Pudy Budi Utomo Desi Fitriani Dewi, Selva R. Dian Marcia, Dian Doddy M. Soebadi Dominicus Husada Dwiyanti Puspitasari, Dwiyanti Eduardus Bimo Aksono Herupradoto Edward M Putera, Edward M Eko Budi Koendhori, Eko Budi Faisal Faisal Fathmawati Fathmawati Fatimah Arief Fauzia, Kartika A. Fedik Abdul Rantam Firmansyah, Joedhistira Bayu Fitria, Anisa Lailatul Florentina Sustini HAK HOTTA HAK HOTTA Hana Heny Arwati Herman Kosasih HERNOMO ONTOSENO KUSUMOBROTO Hunowu, Ramdan I Gusti Made Reza Gunadi Ranuh Ilma Dzurriyyatan Toyyibah Itja Firdarini, Itja Khairul Bariyah, Khairul Laura Navika Yamani Lindarto, Wira Widjaya M. Qushay, M. Maharani, Aussie Tahta Maria I Lusida, Maria I MARIA INGE LUSIDA MARIA INGE LUSIDA Maria Inge Lusida MOCHAMAD AMIN MOCHAMAD AMIN Mochamad Yusuf Alsagaff MOCHAMMAD THAHA Moses Tende Stephens Muhammad Faizi Muhammad Miftahussurur Muna, Nafdzu Makhmudatul Musofa Rusli Nasronudin Nasronudin Nur Rochmah Nurul Wiqoyah, Nurul Pepy Dwi Endraswari, Pepy Dwi Peter Chilaque Dossen Prihartini Widiyanti Priyo B Purwono, Priyo B Priyo Budi Purwono Retno Handajani Retno Pudji Rahayu Rusli , Musofa Sardjono, Lindawati Alim Septyawati, Ratna Setiawan, Firman Siti Qamariyah Khairunisa, Siti Qamariyah SOETJIPTO . SOETJIPTO . Sri Subekti Sudarmo, Subijanto Marto Sukmawati Basuki Sulistiawati Sunaryo Hardjowijoto TAKAKO UTSUMI Takako Utsumi TAKAKO UTSUMI Taufik Indrawan Tomohiro Kotaki, Tomohiro Vermasari, Naritha Wahyunitisari, Manik Retno Widyatama, Fikri Sasongko YOSHIHIKO YANO YOSHIHIKO YANO Yoshio Yamaoka, Yoshio YOSHITAKE HAYASHI YOSHITAKE HAYASHI Yunita Ratri Adhiningsih Zayyin Dinana