Garuda - Garba Rujukan Digital

p-Index From 2020 - 2025

2.036

P-Index

This Author published in this journals

All Journal Microbiology Indonesia Indonesian Journal of Urology Jurnal Berkala Epidemiologi Indonesian Journal of Tropical and Infectious Disease Belitung Nursing Journal J-Dinamika: Jurnal Pengabdian Kepada Masyarakat JURNAL KESEHATAN MERCUSUAR Majalah Biomorfologi (Biomorphology Journal) CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Jurnal Pengabdian Masyarakat dalam Kesehatan International Islamic Medical Journal Narra J Jurnal Ilmiah Kesehatan (JIKA) Makara Journal of Health Research

Juniastuti Juniastuti

Department Of Microbiology, Medical Faculty, Universitas Airlangga, Surabaya Indonesia-Japan Collaborative Research Center For Emerging And Re-emerging Infectious Diseases Institute Of Tropical Disease, Universitas Airlangga, Surabaya, Indonesia

Author-ID : 293836

Religion Humanities Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

Published : 20 Documents Claim Missing Document

Claim Missing Document

Articles

1 2

HEMATOLOGY PROFILES AND DISEASE SEVERITY OF PEDIATRIC DENGUE VIRUS INFECTION AT A TERTIARY HOSPITAL IN SURABAYA, INDONESIA Annisa Fira Salsabila; Juniastuti; Dominicus Husada; Dwiyanti Puspitasari
Majalah Biomorfologi Vol. 34 No. 1 (2024): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v34i1.2024.1-9

Highlights Dengue virus infections exhibit a spectrum of clinical manifestations, ranging from asymptomatic cases to severe disease, with the potential for fatalities if not managed effectively. Hematology factors significantly contribute to the severity of dengue virus infection. Abstract Background: The escalating incidence of dengue cases in Surabaya, Indonesia, underscores the imperative to comprehend the hematology profiles and disease severity in pediatric patients affected by dengue virus infections (DVI). As the prevalence of DVI continues to surge, understanding the nuanced clinical manifestations becomes paramount for effective management and mitigation of the disease burden. Objective: This study aimed to characterize the hematology profiles and the disease severity of dengue virus infections (DVI) among pediatric patients hospitalized at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia throughout 2019. Material and Method: A retrospective descriptive cross-sectional study was conducted using secondary data from medical records. Pediatric patients aged six months to 18 years were enrolled. A total sampling method comprised 67 patients meeting the inclusion criteria. Result: Severe thrombocytopenia was most commonly observed in dengue hemorrhagic fever (DHF) III cases (36.4%), while leukopenia was predominant in DF cases (42.2%). High hematocrit levels were more prevalent in DHF III cases (27.3%), and high hemoglobin levels were most frequently identified in DHF II and DHF III cases (33% in each case). Significant differences in DVI severity were observed in platelets and hemoglobin levels (p=0.0002 and p=0.0066, respectively) but not in leukocyte and hematocrit levels. Conclusion: Mild thrombocytopenia was prevalent in Dengue Fever (DF), while severe thrombocytopenia was most prevalent in Dengue Hemorrhagic Fever (DHF) grade III. Leukopenia was prominent in DF patients, and platelets and hemoglobin levels varied across severity of DVI. These findings provide insights for improved clinical management and diagnostic criteria refinement.

HEPATITIS B SEROLOGY PROFILES ON CHILDREN AGED 1–13 YEARS OLD IN SUMENEP, MADURA Putera, Edward M; Marcia, Dian; Firdarini, Itja; Amin, Mochamad; Juniastuti, Juniastuti; Purwono, Priyo B; Utsumi, Takako; Lusida, Maria I
Indonesian Journal of Tropical and Infectious Disease Vol. 3 No. 2 (2012)
Publisher : Institute of Topical Disease Universitas Airlangga

Background: Hepatitis B virus (HBV) which was acquired during perinatal or childhood would promote hepatocellular carcinoma with even higher percentage than that which was acquired during adult age. That is why HBV represents a serious public health threat for children. HBV vaccination has been integrated into national expanded programme on immunization (EPI) since 1997. The aimof they study is to investigate the prevalence of HBV among children who were born after 1997 in Sumenep. Material and Methods: a total of 102 children who were born after 1997 were enrolled in this study. All children were admitted in the Emergency Room and Pediatric Ward of dr. H. Moh Anwar General Hospital for some reasons. Written informed consents were obtained from parents/guardians of all the children. Study protocol was reviewed and approved by the Ethics Committees. All of these cases were examined for hepatitis B surface antigen (HBsAg), antibody to HBsAg (Anti-HBs), and antibody to hepatitis B core antigen (Anti-HBc). Result and Discussion: Overall, 6 (5.88%) of 102 samples were positive for HBsAg, 51 (50.00%) of 102 samples were positive for anti-HBs, and 49 (48.04%) of 102 samples were positive for anti-HBc. All the children were born after 1997. Conclusion: HBsAg rate is still high even after universal vaccination program, acquired protective antibodies against hepatitis B surface antigen were sufficient, but there is a suspicion for occult hepatitis B infections (OBI). A further study to confirm OBI is needed.

THE PREVALENCE OF HUMAN IMMUNODEFIENCY VIRUS-1 (HIV-1) SUBTYPES AND TRANSMISSION METHOD AMONG HIV/AIDS INFECTION PATIENT IN TULUNGAGUNG, EAST JAVA INDONESIA Ardianto, Achmad; Khairunisa, Siti Qamariyah; Kotaki, Tomohiro; Witaningrum, Adiana Mutamsari; Qushay, M.; Juniastuti, Juniastuti; Rahayu, Retno Pudji; Widiyanti, Prihartini; Utomo, Budi; Lusida, Maria Inge; Nasronudin, Nasronudin
Indonesian Journal of Tropical and Infectious Disease Vol. 5 No. 5 (2015)
Publisher : Institute of Topical Disease Universitas Airlangga

The rapid epidemic growth of HIV is continuing in Indonesia. There are some factors which have influenced the spreading of this epidemic in Indonesia, such as the poor awareness to avoid unsafe free sex attitude and the sharing of needles and syringes among intravenous drug users (IDUs). The sexual transmission of HIV has also apparently increased in Tulungagung. Commercial sex workers play a significant role in the spread of HIV in Tulungagung. People in Tulungagung have worked at other countries as Indonesian migrants. This condition can cause the increase number of HIV-1 case and the possibility of genetic variation (subtype) HIV-1 in Tulungagung. This research is aimed to analyze the subtype and to determine estimation of transmission mode on infected patient of HIV-1 and AIDS who came to Seruni clinic Dr. Iskak hospital in Tulungagung. 40 HIV?AIDSpatients were interviewed to determine the subtype and the transmission mode. The results showed that 14 of 40 plasma samples (35%) were successfully to amplified and sequenced. OverallCRF01-AE wereidentified as predominant subtype among HIV/AIDS patients in Tulungagung. Based on individual information, 31 of 40 subjects (77%) were heterosexual transmission.

Characteristics Environmental and Anopheles Larva Species In High And Low Clinical Malaria Cases In The Landak District of West Kalimantan Province Bariyah, Khairul; Utomo, Budi; Subekti, Sri; Sustini, Florentina; Juniastuti, Juniastuti; Fathmawati, Fathmawati; Arwati, Heny
Indonesian Journal of Tropical and Infectious Disease Vol. 9 No. 3 (2021)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v9i3.10419

Malaria remains a health problem in Indonesia. West Kalimantan is a malaria endemic area with high and lowincidence. Landak District is one of the malaria endemic area. Malaria cases were found in the areas around illegalgold mining and oil palm plantations. The aims of this study were to describe the characteristics of the breeding sitesand species of Anopheles larvae found in high malaria cases area, namely Amboyo Utara Village and low clinicalmalaria cases, area namely Mandor Village. This research is a descriptive research with cross sectional design. Thesamples were Anopheles larvae collected with Accidental sampling technique in the breeding sites. Environmentalcharacterization of breeding sites were physical characteristic including water temperature and sun exposure,chemical characteristic including water pH and salinity, and biological characteristics including water biota. Theresults of this study ware environmental characteristics that have the potential to breed Anopheles mosquitoes inAmboyo Utara Village, including water temperature 26-30ï‚°C, shandy, water pH 5.0-7.6, salinity 0.2-1.0 ppt, biotaswater hyacinth, grass and tadpole. The Mandor village, water temperature 29-30 ºC, shandy, pH of 6.9-8.0, salinity of0.5 ppt, water biota grass. Anopheles species found in Amboyo Utara village were larvae of An. vagus (94.30%), An.tessellatus (3.42%), An. subpictus (1.62%), An. indefinitus (0.81%) and An. maculatus (0.81%). Characteristics ofbreeding sites in Mandor village were larvae of An. maculatus (11.11%), An. subpictus (3.70%), and An. vagus(85.18%). The conclusion of this study was that di erent species found at breeding sites with di erent environmentalcharacteristics in both high and low malaria areas in Landak District, West Kalimantan Province.

EPIDEMIOLOGY OF ROTAVIRUS INFECTION IN CHILDREN UNDER FIVE YEARS IN DR. SOETOMO HOSPITAL, SURABAYA (2015-2019): Gambaran Epidemiologi Kasus Infeksi Rotavirus Pada Balita di RSUD Dr. Soetomo Pada Tahun 2015-2019 Ana Bilah, Aisah Nur; Dinana, Zayyin; Maharani, Aussie Tahta; Fitria, Anisa Lailatul; Juniastuti; Athiyyah, Alpha Fardah; Darma, Andy; Gunadi Ranuh, I Gusti Made Reza; Sudarmo, Subijanto Marto; Yamani, Laura Navika
Jurnal Berkala Epidemiologi Vol. 12 No. 3 (2024): Jurnal Berkala Epidemiologi (Periodic Epidemiology Journal)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbe.V12I32024.255-262

Background: Diarrhea is the first cause of death for children under five years of age worldwide. In Indonesia, diarrhea cases due to rotavirus infection tend to be detected throughout the year. Purpose: The study was to determine the epidemiology of diarrhea cases due to rotavirus infection of pediatric patients in Dr. Soetomo Hospital, Surabaya based on the variables of person, place, and time. Methods: This type of research uses both descriptive and quantitative methods. The samples used were cases of rotavirus infection in toddlers in Dr. Soetomo Hospital, Surabaya in 2015–2019. Results: From 2015 to 2019, there were about 110 cases (31.98%) of acute diarrhea caused by rotavirus infection at Dr. Soetomo Hospital, Surabaya. The findings revealed that the majority of rotavirus infections (42.73%) occurred in children aged 6-11 months followed 12-23 months (35.45%) and were male (56.36%). The highest cumulative incidence was observed in August 2018 and February 2029, with a value of 1,0. Rotavirus infection was most common among children living in Gubeng sub-District, with 19 cases (17.27%). Conclusion: Epidemiological studies of rotavirus infection by person, place, and time reveal the distribution of disease cases and enable targeted interventions to respond to the disease.

Pemberdayaan Guru Yayasan Pendidikan Al Khairaat Yogyakarta pada Penanggulangan Antimicrobial Resistance: dari UNAIR untuk Indonesia Wahyunitisari, Manik Retno; Koendhori, Eko Budi; Endraswari, Pepy Dwi; Purwono, Priyo Budi; Juniastuti, Juniastuti; Wiqoyah, Nurul; Sardjono, Lindawati Alim; Vermasari, Naritha; Muna, Nafdzu Makhmudatul; Setiawan, Firman; Lindarto, Wira Widjaya; Widyatama, Fikri Sasongko
J-Dinamika : Jurnal Pengabdian Masyarakat Vol 9 No 3 (2024): Desember
Publisher : Politeknik Negeri Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25047/j-dinamika.v9i3.5481

Antibiotics are compounds created by microorganisms to live by destroying their competitors. Antibiotics are commonly used without a prescription to treat symptoms caused by non-bacterial infections. Antibiotic resistance is a global problem. Continuous education is needed by agents of change to overcome this problem. Community service collaboration between the Department of Microbiology-Parasitology, FK Unair, and the Department of Microbiology, Faculty of Medicine, Public Health, and Nursing, Gadjah Mada University with partnerships for the goals teachers from the Al Khairaat Yogyakarta educational foundation, aim to provide an understanding of the proper use of antibiotics. The initial target of transfer of knowledge was successfully measured by increasing participants' post-test results.

Risk Factors of Catheter-Associated Urinary Tract Infections in Hospitalized Patients in Internal Medicine Ward of Tertiary Referral Hospital in Indonesia Hana; Asmarawati, Tri Pudy; Juniastuti
Jurnal Medis Islam Internasional Vol 7 No 1 (2025): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v7i1.6974

Introduction: Urinary Tract Infection (UTI) is the most common type of nosocomial infection. An increase of 80% of nosocomial urinary tract infections is caused by the usage of urinary catheters. Previous studies have found that inpatients are more susceptible to UTI than outpatients. Objective: The Objective of this study is to assess the prevalence and risk factors for internal medicine patients at tertiary referral hospitals in Surabaya with Catheter Associated Urinary Tract Infections (CAUTI). These findings may aid in strategies to minimize CAUTI occurrences. Methods: This study was a single-center cross-sectional study that obtained data from medical records. Data samples were tested using Chi-Square to find a correlation between UTI and age, gender, length of stay, and underlying disease or comorbidities with a p-value of p<0,05. Results: The proportion of patients who experienced CAUTI during May 2020-May 2021 was 32.8%. The characteristics of the sample in this study were in the age range of 28 to 78 years with an average of 54 years. There were four male patients and 17 female patients in the CAUTI group. The p-values for age, gender, duration of hospitalization, and underlying disease or comorbidities were 0.465 (p>0.05); 0.064 (p>0.05); 0.146 (p>0.05); and 0.064 (p>0.05). Conclusions: There was a reduction in the prevalence of CAUTI from 2018 compared to 2020-2021. There were no variables that were significantly associated as risk factors for CAUTI.

Helicobacter pylori sabA, hopQ and hom genotypes as potential genetic biomarkers for gastric mucosal inflammation Hunowu, Ramdan; Fauzia, Kartika A.; Alfaray, Ricky I.; Dewi, Selva R.; Juniastuti, Juniastuti; Yamaoka, Yoshio; Miftahussurur, Muhammad
Narra J Vol. 5 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i2.1917

Helicobacter pylori infection drives heterogeneous gastric pathologies, yet genotype-phenotype correlations in diverse populations remain underexplored. The aim of this cross-sectional study was to investigate the associations between H. pylori virulence genotypes (sabA, hopQ, hom family) and histopathological severity in gastric mucosa among 113 Indonesian dyspepsia patients (mean age: 49.6 years; male predominance: 64.6%). Whole-genome sequencing characterized virulence genotypes, while histopathological grading system using the Updated Sydney System assessed inflammation, atrophy, and bacterial density in the antral and corporal gastric regions. Phylogenetic analysis elucidated strain relatedness. Key genotype frequencies included sabA "on" (40.6%, 43/106), hopQ type I (53.7%, 43/80), and homCL (82.4%, 75/91). Statistical analysis revealed sabA "on" status significantly associated with elevated antral bacterial density (odds ratio (OR) 2.70 and 95% confidence interval (95%CI) 1.10–6.60, p=0.027). The homC variants (homCL/homCS) demonstrated robust associations with chronic inflammation severity (OR: 3.04; 95%CI: 0.99–9.36, p=0.046) and atrophy progression (OR: 4.78; 95%CI: 1.00–22.86, p=0.035), in contrast to the hopQ genotype, which showed no histopathological association. These findings indicated that sabA and homC as critical determinants of gastric microenvironment modulation, potentially through sabA-mediated colonization efficiency and homCL-babA synergistic interactions. While histological profiles predominantly indicated mild atrophy, widespread severe chronic inflammation signals latent progression risks.

Profiles of Deceased Patients with Coronavirus Disease 2019 (COVID-19) and Multidrug-Resistant Bacterial Coinfections at an Indonesian Tertiary Hospital Firmansyah, Joedhistira Bayu; Rusli , Musofa; Juniastuti; Septyawati, Ratna
Current Internal Medicine Research and Practice Surabaya Journal Vol. 6 No. 2 (2025): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v6i2.53649

Introduction: Antibiotic use in coronavirus disease 2019 (COVID-19) patients reached 70% during the pandemic, potentially inducing the invasion of multidrug-resistant organisms (MDROs). This study analyzed patients who died from COVID-19 with MDRO coinfections at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Methods: We conducted a retrospective descriptive study of 120 deceased COVID-19 inpatients from January to December 2021. The inclusion criteria required: (1) positive MDRO cultures from ≥2 specimens, and (2) resistance to ≥1 agent across ≥3 antimicrobial categories. Patients with incomplete records or no antibiotic therapy were excluded. The data were presented using descriptive statistics to characterize patient demographics, microbiological profiles, and antimicrobial resistance patterns. Results: The patients were predominantly male (60%), aged 41–80 years (78.33%), and hospitalized for 8–30 days (53.44%). The microbiological examinations revealed blood cultures as the main specimen source (43.10%), followed by sputum (27.59%), urine (19.40%), pus (7.33%), and cerebrospinal fluid (2.59%). The prevalent isolates varied by specimen type: coagulase-negative staphylococci (51%) in blood, Pseudomonas spp. in pus (17.65%), Klebsiella spp. in sputum (26.69%), and Escherichia coli in urine (37.78%). The cerebrospinal fluid cultures showed an equal distribution of Gram-negative bacilli, Gram-positive bacilli, and Gram-positive cocci (33.33% each). Conclusion: This study characterizes the profiles of fatal COVID-19 cases with MDRO coinfections, demonstrating a predominance of older male patients with prolonged hospitalization. The identified resistance patterns and pathogen distribution, notably coagulase-negative staphylococci in blood, highlight the importance of improved infection surveillance and antibiotic stewardship to minimize the risk of coinfection in the future. Highlights: 1. While existing studies have examined multidrug-resistant organism (MDRO) coinfections in COVID-19 globally, this work offers a valuable standalone characterization of a high-risk subgroup in Indonesia, where resistance patterns arising from antimicrobial use during the pandemic created unique clinical challenges. 2. This study provides comprehensive data on the mortality of COVID-19 patients with MDRO coinfections at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, enhancing medical personnel's awareness of MDRO bacterial transmission and informing improvements in antibiotic stewardship programs within hospitals.

Risk Factors of Acute Gastroenteritis and the Implementation of Community-Based Total Sanitation in Banyuwangi, Indonesia: A Cross-sectional Study Al Karina, Citra; Juniastuti, Juniastuti; Utomo, Budi; Mertha Adnyana, I Made Dwi
Makara Journal of Health Research
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Background: In Banyuwangi Regency, Indonesia, diarrhea remains a major health problem, even though the community-based total sanitation (CBTS) program has been implemented for ten years. This household survey study aimed to identify the risk factors of acute gastroenteritis (AGE) and to evaluate the implementation of CBTS in Banyuwangi Regency. Methods: A cross-sectional study was conducted in Banyuwangi Regency. Characteristic data from patients with AGE were collected from the two primary healthcare working areas, followed by collecting data of their family members and CBTS in their houses. Data were obtained through interviews and direct observation. The CBTS evaluation results were analyzed descriptively, while risk factors were analyzed statistically using Chi-square and logistic regression tests. Results: Data were collected from 278 individuals across 96 families. Age and educational level were significantly associated with AGE. Individuals aged ≥19 years were less likely to have AGE (p < 0.001, OR = 0.385, 95% CI = 0.228-0.651). Most households had poor CBTS facilities of handwashing (76.0%), garbage (80.2%), and liquid waste disposal (88.5%). Conclusion: Age and education level were identified as individual risk factors for AGE. Most households had three poor facilities of CBTS. These findings might be considered in public health interventions to reduce AGE incidence in Banyuwangi Regency.

Co-Authors A.A. Ketut Agung Cahyawan W Achmad Ardianto, Achmad Adhiningsih, Yunita Ratri Adiana Mutamsari Witaningrum Adnyana , I Made Dwi Mertha Ahmad Suryawan Al Karina, Citra Alfaray, Ricky I. Alpha Fardah Athiyyah Ana Bilah, Aisah Nur Andy Darma Annisa Fira Salsabila Asmarawati, Tri Pudy Budi Utomo Desi Fitriani Dewi, Selva R. Dian Marcia, Dian Doddy M. Soebadi Dominicus Husada Dwiyanti Puspitasari, Dwiyanti Eduardus Bimo Aksono Herupradoto Edward M Putera, Edward M Eko Budi Koendhori, Eko Budi Faisal Faisal Fathmawati Fathmawati Fatimah Arief Fauzia, Kartika A. Fedik Abdul Rantam Firmansyah, Joedhistira Bayu Fitria, Anisa Lailatul Florentina Sustini HAK HOTTA HAK HOTTA Hana Heny Arwati Herman Kosasih HERNOMO ONTOSENO KUSUMOBROTO Hunowu, Ramdan I Gusti Made Reza Gunadi Ranuh Ilma Dzurriyyatan Toyyibah Itja Firdarini, Itja Khairul Bariyah, Khairul Laura Navika Yamani Lindarto, Wira Widjaya M. Qushay, M. Maharani, Aussie Tahta Maria I Lusida, Maria I Maria Inge Lusida MARIA INGE LUSIDA MARIA INGE LUSIDA MOCHAMAD AMIN MOCHAMAD AMIN Mochamad Yusuf Alsagaff MOCHAMMAD THAHA Moses Tende Stephens Muhammad Faizi Muhammad Miftahussurur Muna, Nafdzu Makhmudatul Musofa Rusli Nasronudin Nasronudin Nur Rochmah Nurul Wiqoyah, Nurul Pepy Dwi Endraswari, Pepy Dwi Peter Chilaque Dossen Prihartini Widiyanti Priyo B Purwono, Priyo B Priyo Budi Purwono Retno Handajani Retno Pudji Rahayu Rusli , Musofa Sardjono, Lindawati Alim Septyawati, Ratna Setiawan, Firman Siti Qamariyah Khairunisa, Siti Qamariyah SOETJIPTO . SOETJIPTO . Sri Subekti Sudarmo, Subijanto Marto Sukmawati Basuki Sulistiawati Sunaryo Hardjowijoto TAKAKO UTSUMI TAKAKO UTSUMI Takako Utsumi Taufik Indrawan Tomohiro Kotaki, Tomohiro Vermasari, Naritha Wahyunitisari, Manik Retno Widyatama, Fikri Sasongko YOSHIHIKO YANO YOSHIHIKO YANO Yoshio Yamaoka, Yoshio YOSHITAKE HAYASHI YOSHITAKE HAYASHI Yunita Ratri Adhiningsih Zayyin Dinana

Title

Found 20 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 20 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 20 Documents
Search