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All Journal International Journal of Public Health Science (IJPHS) ACTA VETERINARIA INDONESIANA Jurnal Sain Veteriner Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Kesehatan Lingkungan indonesia Jurnal Ilmu Dasar e-Journal Pustaka Kesehatan Jurnal Kesehatan Masyarakat Althea Medical Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Majalah Geografi Indonesia Jurnal Kesehatan Jurnal Kesehatan Andalas Folia Medica Indonesiana Damianus Journal of Medicine Journal of Agromedicine and Medical Sciences Jurnal Media Gizi Indonesia (MGI) JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health) Majalah Kedokteran Sriwijaya Universa Medicina Jurnal Bioteknologi & Biosains Indonesia (JBBI) Journal Of Vocational Health Studies Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Al-sihah: The Public Health Science Journal Jurnal Medik Veteriner SRIWIJAYA JOURNAL OF MEDICINE Journal of Health Sciences JHECDs: Journal of Health Epidemiology and Communicable Diseases JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Berita Kedokteran Masyarakat JEBIMAN: Jurnal Ekonomi, Bisnis, Manajemen dan Akuntansi Jember Medical Journal (JMJ) Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery) ASPIRATOR - Journal of Vector-Borne Diseases Studies
Bagus Hermansyah
Departemen Parasitologi, Fakultas Kedokteran Universitas Jember, Jalan Kalimantan 37 Kampus Tegal Boto, Jember, Jawa Timur 68121
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Control & Systems Engineering Earth & Planetary Sciences Environmental Science Health Professions Immunology & microbiology Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Stall Sanitation Associated with Cryptosporidium sp. Infection on Calf and Cattle Farmer Ramadhani, Rafindra; Nurdian, Yudha; Rachmawati, Dwita Aryadina; Utami, Wiwien Sugih; Armiyanti, Yunita; Hermansyah, Bagus; Rahardjo, Angga Mardro
Jurnal Medik Veteriner Vol. 5 No. 2 (2022): October
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol5.iss2.2022.178-187

Abstract

Increasing the cattle population can increase the amount of the waste. Poor management of cage sanitation has the risk of causing a decrease in the health conditions of cattle farmers, such as: diarrhea, nausea, vomiting, and itching, as many as 50% of cattle with diarrhea are infected with Cryptosporidium sp. The highest infection of Cryptosporidium sp. in cattle found in calves. The calf can excrete 1í—1010 oocysts of Cryptosporidium sp. per day. Cryptosporidium sp. also has the potential to cause zoonotic infections that are transmitted from animals to humans. The study aims was to determine the relationship between stall sanitation and Cryptosporidium sp. to calf and cattle farmer. The type of this research was analytic observational with a cross sectional approach conducted in Jatian Village, Pakusari, Jember during October 2021 - March 2022. The primary data was obtained through interviews and observations. The feces of calves and cattle farmer were collected and examined using sedimentation method and modified Ziehl-Neelsen (MZN) staining method. The statistical test used is the chi-square test. The results showed that the prevalence of Cryptosporidium sp. in calves by 14,3% and on cattle farmer by 4,8%. The bivariate analysis showed that that stall location and waste handling were associated with Cryptosporidium for calf (p≤0.05), and there were no variables that were significantly related to infection in cattle farmers (p>0,05). Cryptosporidium sp. in calves and humans can be caused by several factors, such as environmental factors and hosts. Preventive measures such as maintaining a clean environment including cowshed sanitation and personal hygiene need to be taken to reduce the risk of Cryptosporidium infection from calves to humans, and vice versa.
Correlation between Sanitation of Cow Stalls on Flies Density and Cryptosporidium sp. Manifestations Drajad, Rahadinda Mutia Dhamar; Nurdian, Yudha; Astuti, Ida Srisurani Wiji; Utami, Wiwien Sugih; Armiyanti, Yunita; Hermansyah, Bagus
Jurnal Medik Veteriner Vol. 6 No. 1 (2023): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol6.iss1.2023.21-28

Abstract

The purpose of this study was to determine the correlation of stall sanitation on fly density and Cryptosporidium sp. presence on housefly. This study type was observational with a cross sectional approach in Jatian Village, Pakusari District, Jember Regency on December 2021 - February 2022. Data type was primary data that obtained using interview and observation. The correlation test that used was contingency coefficient test. The results showed that 77,5% of the stall had high fly density. Prevalence of Cryptosporidium sp. on housefly was 10%. Statistical analysis showed that cattle manure handling affected fly density (p≤0,05) with low correlation (r=0,384), meanwhile air vents affected Cryptosporidium sp. presence on housefly (p≤0,05) with low correlation (r=0,359). Farmers were suggested to keep the stall sanitation optimal to prevent Cryptosporidium transmission to humans.
Risk Factor Analysis of Cryptosporidium sp. Contamination in Dairy Cow Milk in Jember, Indonesia Sa'bani, Begawan; Hermansyah, Bagus; Sofiana, Kristianningrum Dian; Armiyanti, Yunita; Utami, Wiwien Sugih
Jurnal Medik Veteriner Vol. 7 No. 1 (2024): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol7.iss1.2024.177-186

Abstract

This study aimed to determine the factors influencing Cryptosporidium sp. contamination in dairy cow milk in Jember. This study used an observational analytic design with a cross-sectional approach. The number of samples in this study was 30 cow farmers, using a purposive sampling technique. Data sources were obtained from questionnaire interviews, observation sheets, and laboratory examination results of milk samples. Data were then analyzed using univariate, bivariate, and multivariate analysis. Bivariate analysis used the Kruskal-Wallis comparison test, and multivariate analysis used the logistic regression test. The results showed Cryptosporidium sp. contamination in the milk of dairy cows by 6.7%. Most of the cow farmers in Jember had sufficient knowledge (40%), milking hygiene was categorized as sufficient (70%), and equipment sanitation was sufficient (66.7%). The statistical analysis showed no significant relationship between farmers' knowledge and equipment sanitation and Cryptosporidium sp. contamination (p > 0.05). There was a significant relationship between milk hygiene and Cryptosporidium sp. contamination in dairy cow milk in Jember (p < 0.05). In conclusion, milking hygiene was a risk factor affecting Cryptosporidium sp. contamination in dairy cow milk in Jember.
The 32 kDa Outer Membrane Proteins of Klebsiella pneumoniae Acts as A Bacterial Adhesin Agustina, Dini; Shodikin, M. Ali; Nugraha, Bima Setia Sandya; Mufida, Diana Chusna; Suswati, Enny; Hermansyah, Bagus
Jurnal ILMU DASAR Vol 23 No 2 (2022)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/jid.v23i2.25435

Abstract

Klebsiella pneumoniae is a bacterium that often causes infection in the human body. At present K. pneumoniae can resist some of the antibiotics it has associated with modification of one of the virulence factors possessed by K. pneumoniae. One virulence factor of K. pneumoniae as pathogen bacteria is Outer Membrane Protein (OMP). The study of adhesin factors in K. pneumoniae involving hemagglutinin and adhesin proteins that have been found in the OMP 20 kDa and 40 kDa, but there is still no research that discusses the role of 32 kDa OMP as a hemagglutinin protein and adhesin. The purpose of this study is to determine the role of 32 kDa outer membrane of K. pneumoniae as hemagglutinin and adhesin proteins. After isolation of Outer Member Protein (OMP) from the K. pneumoniae, which then carried out a hemagglutination test using mice erythrocyte cells and adhesion test using mice enterocyte cells. The results of the hemagglutination test using mice erythrocyte cells obtained the highest hemagglutination titer for the molecular weight of 32 kDa in titers 1/4. The adhesion index with dilution titer has a significant relationship, with a conversion coefficient of 0,813 which means the dilution titer with the OMP adhesion index has a strong relationship with the direction of a positive relationship. The regression test results obtained an R-value of 0,813 which shows a strong relationship, while the R2 value is 66.1%. Conclusion in this study is 32 kDa outer membrane proteins of K. pneumoniae acts as a bacterial adhesin.
Increased Interleukin-4 in Farmers With Ascariasis in Rural Jember Rahmadhan, Adiz Dwiputra; Armiyanti, Yunita; Hermansyah, Bagus; Helianti, Dina; Nurdian, Yudha
Jurnal ILMU DASAR Vol 22 No 1 (2021)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/jid.v22i1.15921

Abstract

Ascaris lumbricoides is nematode which often infest human in the world. The infestation of A. lumbricoides in the human will trigger the formation of Th2 immune responses through increased interleukin-4 released by innate immune cells. Th2 immune response generates B lymphocyte cells to produce IgE antibodies to eliminate A. lumbricoides. Therefore, IL-4 is a marker of Th2 immune response. The purpose of this study was to determine the prevalence of ascariasis and an increase of IL-4 in planters infested with A. lumbricoides as a marker of Th2 immune response. Our study was observational analytic with cross sectional design. 230 planters who were willing to be involved in the study gave stool samples for the diagnosis of ascariasis. 20 people who were positive for ascariasis and 20 people who were negative selected randomly for blood plasma samples. IL-4 levels in blood plasma were measured using ELISA. Differences in IL4 levels between positive and negative ascariasis were analyzed by the Mann Whitney statistical test with p value ≤ 0.05. The prevalence of ascariasis among planters in rural area of Jember was 16,52% which was included low prevalence. Univariate analysis showed that the mean and median levels of IL-4 ascariasis were greater than those of healthy planters. Mann Whitney test results showed that there were differences in levels of IL-4 between ascariasis and healthy planters (p≤0.05). Increased levels of IL-4 in planters with ascariasis indicate that A. lumbricoides infection triggers the formation of Th2 immune response as a mechanism for eliminating A. lumbricoides. Keywords: Interleukin-4, A. lumbricoides, Th2 immune response.
EOSINOPHILIA AS A PREDICTOR MORBIDITY OF SOIL- TRANSMITTED HELMINTHIASES AMONG WIDODAREN PLANTATION WORKERS IN JEMBER Primadana, Aditya; Nurdian, Yudha; Agustina, Dini; Hermansyah, Bagus; Armiyanti, Yunita
Journal of Vocational Health Studies Vol. 3 No. 2 (2019): November 2019 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (301.887 KB) | DOI: 10.20473/jvhs.V3.I2.2019.47-52

Abstract

Background: Helminthiasis is a neglected tropical disease and still remain a health problem in tropical and sub-tropical countries, including Indonesia. According to WHO, approximately 1,5 billion people or 24% of the world's population, are infected with Soil-Transmitted Helminth (STH). Morbidity is directly related to the intensity of STH infestation. Some of the studies shown a significant correlation between eosinophilia and helminthiasis. Eosinophilia on the blood smear examination may be used as a marker of STH infestation. Purpose: to determine the correlation between Soil-Transmitted Helminthiases and eosinophilia as a predictor of morbidity of STH infestation among Widodaren Plantation Workers in Jember. Method: This observational analytical study use the Kato-Katz method to determine infestation of STH and its intensity measured by egg count per gram stool (EPG). Blood smear examination stained with Giemsa conduct to determine eosinophil count. Result: Prevalence of STH infestation was 22,7% (15/66). Ascaris lumbricoides infection was 13,6% (9/66) and Hookworm infection was 4,5% (3/66). There is mixed infection between A. lumbricoides and Hookworm, the prevalence was 4,5%% (3/66). All of the infection intensity was light. The prevalence of eosinophilia was 27,2% (18/66). There was a significant correlation between STH infection and eosinophilia (P=0,000) but, there was a very weak correlation between the intensity of STH infection and eosinophilia (r=0,281; p=0,258). Conclusion: The prevalence of STH infection among Widodaren Plantation Workers is 22,7% and predominated by A. lumbriocides. There is a positive correlation between intensity of STH infection and eosinophilia as predictor morbidity of STH infection with very weak power.
Combination Therapy for Cryptosporidiosis in Immunocompromised Patients Wiwien Sugih Utami; M.S. Irham Rozaq; Laksmi Indreswari; Cholis Abrori; Bagus Hermansyah
Folia Medica Indonesiana Vol. 60 No. 4 (2024): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/fmi.v60i4.60340

Abstract

Cryptosporidium sp. is a gastroenteritis-causing pathogen that may increase mortality and morbidity in immunocompromised patients. Diarrhea is a common problem among acquired immunodeficiency syndrome (AIDS) patients, with 30–60% of patients in developed countries and 90% in developing countries affected. The prevalence of cryptosporidiosis is 3–5% of the global population, with 14.42% of those affected being immunocompromised. There is currently no vaccine available to prevent cryptosporidiosis, while nitazoxanide monotherapy is ineffective in eradicating the organism in immunocompromised hosts and malnourished children. This study aimed to determine the most effective combination therapy for cryptosporidiosis in immunocompromised patients. This study used a systematic review design and implemented eligibility criteria for the literature search across PubMed, ScienceDirect, Epistemonikos, Google Scholar, Nature, Springer, and John Wiley databases. The search utilized specific keywords and Boolean operators, i.e., “Cryptosporidium,” OR “cryptosporidiosis,” AND “combination therapy,” OR “combination treatment,” AND “immunocompromised.” Two cohort studies and two case reports were selected, three of which used a nitazoxanide and azithromycin combination as the intervention, whereas only one cohort study used a nitazoxanide and fluoroquinolone combination. The studies comprised 54 samples from post-kidney transplantation patients and one sample from an acute lymphoblastic leukemia (ALL) patient. The nitazoxanide and fluoroquinolone combination showed superior outcomes than the nitazoxanide and azithromycin combination. The stool clearance was significantly lower with nitazoxanide monotherapy than the nitazoxanide and fluoroquinolone combination (OR=0.65, 95% CI=0.34–0.92, p=0.01). However, it was non-significantly lower with the nitazoxanide and azithromycin combination compared to monotherapy (OR=0.27, 95% CI=0.01–5.77, p=0.24). Nitazoxanide monotherapy exerted a significantly lower effect than the nitazoxanide and fluoroquinolone combination in stopping diarrhea symptoms (OR=0.45, 95% CI=0.21–0.81, p=0.004). In conclusion, a combination therapy using nitazoxanide and fluoroquinolone for cryptosporidiosis in immunocompromised patients offers more favorable outcomes compared to monotherapy, particularly in stopping diarrhea and enhancing stool clearance.
DAMPAK GLOBALISASI EKONOMI TERHADAP PERDAGANGAN INTERNASIONAL DI PASCA PANDEMI (2020-2024) Tutiana Bayati; Tiara Ajeng Dewita; Sri Rahmanita; Raissa Puan Andrina; Bagus Hermansyah; Dwita Sakuntala
JEBIMAN : Jurnal Ekonomi, Bisnis, Managemen dan Akuntansi Vol. 3 No. 2 (2025): In Press MARET
Publisher : CV. ADIBA AISHA AMIRA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This study aims to analyze the impact of economic globalization on international trade during the COVID-19 pandemic period (2020-2024). Using a qualitative method based on literature and previous empirical studies, the research examines changes in international trade patterns, the challenges faced by countries, and the adaptive strategies implemented to address global challenges. The data used in this study were sourced from scholarly articles published between 2020 and 2024. The findings indicate that economic globalization has persisted despite various challenges arising from the pandemic, with technology and trade policies serving as key determinants. This study highlights the importance of flexible trade policy adaptations to enable countries to remain competitive in the global market.
Soil-Transmitted Helminth Infection and Macronutrient Intake among Stunted Toddlers in Panti Sub-district, Jember Ghaiska Najma Amnur; Yunita Armiyanti; Irawan Fajar Kusuma; Leersia Yusi Ratnawati; Wiwien Sugih Utami; Bagus Hermansyah
Media Gizi Indonesia Vol. 20 No. 1 (2025): MEDIA GIZI INDONESIA (NATIONAL NUTRITION JOURNAL)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v20i1.74-80

Abstract

Soil-transmitted helminth (STH) infections are one of the most common infectious diseases in the developing world, with prevalence rates as high as 65%. STH infections generally affect the digestive system, which can reduce appetite and nutrient absorption. This study aimed to determine the association between STH infection and macronutrient intake in stunted toddlers aged 12-36 months in Panti Sub-district, Jember Regency. This study used observational analysis method with cross-sectional approach. The total number of subjects was 83 stunted toddlers. Data on STH infection were collected through fecal examination and 2x24 hour food recall questionnaire to assess their macronutrient intake. The results of the study showed that the prevalence of STH was 4.8% with species identified in the examinations such as Ascaris lumbricoides (2.4%) and hookworm (2.4%). The majority of macronutrient intake was considered sufficient for protein (77.1%), deficit for carbohydrate (94%) and fat (77.1%). Bivariate analysis using the contingency coefficient correlation test showed that there was no significant correlation between STH infection and macronutrient intake. Based on the results of this study, macronutrient intake may be influenced by other factors such as the role of parents in preparing nutritious food, economic status, and mild degree of infection. However, the underlying mechanism remains unclear and should be further investigated.
Hubungan Infeksi Soil-Transmitted Helminths (STH) dengan Angka Kejadian Tuberculosis (TB) pada Balita Stunting di Kecamatan Rambipuji Ayundasari, Asti; Hermansyah, Bagus; Nurmaida, Eny; Utami, Wiwien Sugih; Armiyanti, Yunita; Sulistyaningsih, Erma
Jurnal Kesehatan Andalas Vol. 13 No. 2 (2024): July 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i2.2386

Abstract

Infection is one of the factors associated with stunting. The relationship between stunting and infection can have reciprocal effects. Stunting can increase the risk of infection. Conversely, infections such as Soil-Transmitted Helminths (STH) and Mycobacterium tuberculosis (M. tuberculosis) can also increase the risk of stunting. Objective: To analyzed the correlation between STH infection and the incidence of tuberculosis (TB) in stunting toddlers. Methods: The subjects of this study were 108 stunting toddlers obtained from a simple random sampling method. It was conducted from May 2023 to March 2024 in several villages within the Rambipuji District of Jember Regency, including Gugut, Rambigundam, Pecoro, and Kaliwining. The statistical analysis used in this study was the contingency coefficient test. Results: Findings revealed that the occurrence of STH infection with TB in stunting toddlers was 0%. Conclusion: There is no statistically significant relationship between STH infection and the incidence of TB in stunting toddlers in the Rambipuji District, Jember Regency.Keywords: soil-transmitted helminths, tuberculosis, stunting
Co-Authors Achmad Maududie Achmad Nazalal Furqon Adilah Julinar Irianti Afifatun Hasanah Agustina Tri Endharti Ahmad Hasbi Al-Muzaky Alfianti, Nita Angga Mardro Raharjo Ardyansyah, Rizky Robeth Arifin, Mochammad Samsul Asis Fitriana Ayundasari, Asti Azham Purwandhono Aziz, Ayu Munawaroh Billy Jusup Kurniawan Brillian Adexa Yudinda Burhan, Niniek Cholis Abrori, Cholis Cicih Komariyah Desi Dwi Cahyani Diana Chusna Mufida Dicky Setiawan Didi Candradikusuma Didi Candradikusuma Dina Helianti Dinda Ayu Wanodya Supriatiningsih Dini Agustina Drajad, Rahadinda Mutia Dhamar Dwita Aryadina Dwita Aryadina Rachmawati Dwita Sakuntala Edda Rachmadenawanti El Milla, Kardiana Izza Ellen Ocktavironita Elvia Rahmi Marga Putri Enny Suswanti ENNY SUSWATI Eny Nurmaida Epafroditus Sanjaya Adiguna Erfan Efendi Erma Sulistyaningsih Erma Sulistyaningsih Febrianti, Zahrah Fitri, Nadya Eka Ghaiska Najma Amnur Habib Mustofa Habibi, Ali Hanu Neda Septian Heni Fatmawati Hidayat Sujuti Ida Srisurani Wiji Astuti Ika Rahmawati Sutejo Indra Samudra Rahmat Irawan Fajar Kusuma Ivan Iqbal Baidowi Jauhani, M. Afiful Jauhar Firdaus Josef Sem Berth Tuda Kesy Sasta Handani Kristianningrum Dian Sofiana Kusiyanto Taslim, Fitranda Lailatis Shofia Laili, Nikmatul Laily Nurhayati Laksmi Indreswari Laksmi Indreswari Leersia Yusi Ratnawati Loeki Enggar Fitri M. Ali Shodikin M.S. Irham Rozaq Made Masagung Kawiartha Mash’ab Zirrun Al-Qomah Muhammad Afiful Jauhani Muhammad Alif Taryafi Muhammad Dimas Arya Candra Permana Muhammad Ryznar Faisal Nur Luqmani Nabila Putri Anissa Nexia Nevarachell Onny Amirsyah Nidya Husna Kholidah Niniek Burhan Nita Alfianti Nugraha, Bima Setia Sandya Nurmaida, Eny Nurul Furqooniyah Pangestu, Ahmad Yudho Hadi Pralampita, Pulong Wijang Primadana, Aditya Putra, Muhamad Dwi Eka Putri, Elvia Rahmi Marga Qintar Layallia Faza Rahardjo, Angga Mardro Rahmadhan, Adiz Dwiputra Rahmi, Aulya Raissa Puan Andrina Ramadhani, Rafindra Rena Normasari Rezza Putri Mahartika Risyanto, Chusnul Aulia Arisny Putri Sa'bani, Begawan Sakinah, Elly N Salsabila, Yuna Annisa Salsabilla, Safira Putri Nur Samsul Arifin Saputra, Antonius Dwi Sarah Andriani Selly Silfana Liensa septa surya wahyudi, septa surya Shabri, Hammam Arif Shodikin, M Ali Shodikin, M. Ali Shofia, Lailatis Siti Zulaikha Sri Rahmanita Sugiyanta Sugiyanta Supangat Supangat Syamsuddin, Alif Fazduani Tiara Ajeng Dewita Tristianti, Farmitalia Nisa Tuda, Josef Sem Berth Tutiana Bayati Umar Zein Wiwien Sugih Utami Wiwin Sugih Utami Wulandari, Lindi Priyantika Tri Yoga Setyo Yonas Hadisubroto Yudha Nurdian Yuli Hermansyah Yuli Hermansyah Yuli Rahmantia, Vania Yuna Annisa Salsabila Yunita Armianti Yunita Armiyanti Zahrah Febianti Zulaikha Rizqina Rahmawati