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Journal : Journal Of Carbazon

The antinematicidal activity of vitamin E and its derivatives on Sterinernema feltieae Khairan, Khairan; Idroes, Rinaldi; Murniana, Murniana; Diah, Muhammad
Journal of Carbazon Vol 1, No 2 (2023): December 2023
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v2i1.35776

Abstract

Vitamin E is found naturally in some foods, and also available as a dietary supplement. "Vitamin E" is the fat-soluble compounds with distinctive antioxidant activities. The vitamin E acts as an antioxidant, which protects cell membranes. Sterinernema feltieae was selected as a test organism is because this organism is a complex organism and can be used as a model for whole organisms. The objective of this study is to evaluate the activity of vitamin E and its derivatives on Sterinernema feltieae. The results showed that the derivative of vitamin E (C37H55NO3) was most active against S. feltiae with the LD50 value was 207.77 M, followed by vitamin E (C29H50O2) with the LD50 value was 209.09 M. These results indicated that derivative of vitamin E (C37H55NO3) exerts more potent toxicity than vitamin E against Sterinernema feltieae.
Garlic Mixed Olive Oil Cream Formulation and Its Activity Against A Clinical Isolate of Staphylococcus aureus Khairan, Khairan; Zahraty, Ifrah; Idroes, Rinaldi
Journal of Carbazon Vol 1, No 1 (2023): June 2023
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jokarbazon.v1i1.32825

Abstract

Garlic or Allium sativum is known containing of organosulphur compounds. These compounds are known have potential as antimicrobial, antivirus, and anticancer. The purpose of this study is to determine the activity of garlic mixed olive oil (GMO2) cream against the clinical isolate of Staphylococcus aureus and its evaluation by observing the organoleptic, homogeneity, pH, spread ability, stickiness, and viscosity. The result showed that GMO2 was able to inhibit the growth of Staphylococcus aureus bacteria at concentrations of 25 and 50 mg/ml. Meanwhile, the formulation of GMO2 cream at concentration 25 mg/ml was done by poisoned food method showed no activity against clinical isolate of Staphylococcus aureus. In this study, vanishing cream was used as negative control. The evaluation of GMO2 cream at concentration of 25 mg/mL has stability in organoleptic and homogeneity after the cycling test. The pH value of GMO2 cream was approximately equal to vanishing cream. The results of spread ability and stickiness tests indicated that GMO2 cream had the spreading and sticking strength which satisfied with the standard cream in range 5-7 and 4 respectively. The viscosity value of GMO2 cream were decreased after the cycling test. The stability test result showed that of GMO2 cream was stable after the cycling test.
Co-Authors Abd Rahman, Sunarti Ahmad Sodiq, Ahmad Ahmad, Khairunnas Aini, Hanipah Aisya, Mauly Rahadatul Akmal Muhni Akyuni, Qurrata Alfia, Reni Septri Amalia Sutriana Amanda, Rosi Arini, Musfira Asep Rusyana Aulina, Aulina Azzahra, Putri Badriyah, Qurotul Boy M. Bachtiar Claus Jacob, Claus Deliana, Fitri Diah, Muhammad Diana Setya Ningsih, Diana Eko Suhartono El-Shazly, Mohamed Essy Harnelly Estevam, Ethiene Castellucci Faddillah, Vira Fajar Fakri FARADILLA, FARADILLA Fauzi, Fazlin M. Fikrinda Fikrinda Ghazi Mauer Idroes Gholib Gholib, Gholib Harahap, Saima Putri Hasbi, Salsa Yubila Hery Widijanto Hewindati, Yuni Tri Hifnalisa Hifnalisa Hilda Maisyarah, Hilda Idroes, Ghalieb Mutig Idroes, Ghazi M. Idroes, Ghifari Maulana Illian, Didi Nurhadi Isnaini, Nadia Iswahyudi Jannah, Rizka Auliatul Karl Herbert Schaefer, Karl Herbert Kartini Hasballah KAZWAINI, KAZWAINI Kemala, Pati Khalijah Awang Kusumo, Fitranto Lala, Andi Lubis, Vanizra F. Mahdi Abrar Mahmani, Sri Maulana, Addrian Maulana, Aga Maulydia, Nur B. Maulydia, Nur Balqis Medyan Riza Mirda, Erisna Mohd Fauzi, Fazlin Mubaraq, Farhil Muhammad Bahi Muliadi Ramli Munawita, Munawita Munira, Alya Murniana Murniana Musdalifah, Annisa Musvira, Intan Nabila, Fiki Farah Nadirah, Siti Nasrudin Ningsih, Diana S. Nova Eriana, Cut Noviandy, Teuku R. Nurul Husna Patwekar, Mohsina Prasetio, Rasi Purwaendah, Elisa Rahman, Sunarti Abd Rawanita, Mesi Rina Sriwati Rinaldi Idroes Risyad, Syukri Rizki, Risnanda Farzia Roslizawaty Roslizawaty, Roslizawaty Salaswati, Salaswati Salsabila, Indah Sari, Fadia Siregar, Tongku N. Soleman, Soleman Sreeramanan Subramaniam Suhendrayatna Suhendrayatna Suryawati Suryawati Syafruddin Syafruddin Syahputra, Nanda Syamsiar, Syamsiar Teuku Rizky Noviandy Thahar, Aufa Sabrina Thomas Schneider, Thomas Triana Hertiani Trina E. Tallei, Trina E. TRINA EKAWATI TALLEI Wasistha, Nurainun Intan Zahraty, Ifrah Zahriah, Zahriah Zubaidah R, Zubaidah Zuchra Helwani, Zuchra Zulfadli Zulfadli