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All Journal Journal of Mathematical and Fundamental Sciences MPI (Media Pharmaceutica Indonesiana) Pharmascience Jurnal Kajian Ilmiah Kesehatan Dan Teknologi (JKIKT) Jurnal Biomedika CERATA Jurnal Ilmu Farmasi Jurnal Pengabdian Kepada Masyarakat (Mediteg) Budimas : Jurnal Pengabdian Masyarakat International Journal of Clinical Inventions and Medical Sciences (IJCIMS) Borneo Journal Of Pharmascientech Jurnal Pengabdian UNDIKMA Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Kesehatan (JIKA) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Pengabdian Ilung (Inovasi Lahan Basah Unggul) Jurnal Bakti Untuk Negeri Sinteza CERATA Jurnal Pengabdian Masyarakat Panacea Borneo Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Pharmacon: Jurnal Farmasi Indonesia Jurnal Sains dan Kesehatan Jurnal Kesehatan Qamarul Huda
Normaidah, Normaidah
Program Studi Pendidikan Profesi Apoteker, Fakultas Matematika Dan Ilmu Pengetahuan Alam, Universitas Lambung Mangkurat, Banjarbaru, Indonesia
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : Sinteza

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Bioactive Compound Profiling of Ethyl Acetate Fraction from Oil Palm (Elaeis guineensis Jacq.) Leaves using Liquid Chromatography High Resolution Mass Spectrometry (LC-HRMS) Setiawan, Deni; Hadi, Samsul; Mahdi, Nur; Mardiati, Nurul; Normaidah; Hadiah Akbar, Nabila; Rasyid Ridha, Muhammad; Apriliany, Fitri
Sinteza Vol. 5 No. 2 (2025): August
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v5i2.30147

Abstract

Oil palm leaves could yield various health benefits, potentially leading to innovative applications in natural remedies, supplements, and dietary products. Targeted extraction and sophisticated analytical methods have become necessary for investigating bioactive compounds in plant materials. The combination of liquid chromatography and high-resolution mass spectrometry (LC–HRMS) makes for a potent technique for analyzing a wide range of metabolites, allowing for the precise and sensitive identification of various plant compounds. This investigation aimed to examine the active compounds in the ethyl acetate fraction of Elaeis guineensis leaves using LC–HRMS to identify potential new avenues for drug research. The simplicia was extracted by completely immersing 500 g of granules in acetone for three days. The crude extract was fractionated with n-hexane, ethyl acetate, and n-butanol solvents to separate components according to their polarity. The ethyl acetate part was analyzed using LC–HRMS with specific settings, including a temperature of 30°C and a gas flow rate of 11.01 L/min. The extract yield from dense oil palm leaves was 32.5 g, equivalent to 6.5%. Subsequently, the components were separated by fractionating the complete yield. The n-hexane fraction yield was 7.085 g or 21.83%, the ethyl acetate fraction yield was 3.38 g or 10.4%, the n-butanol fraction yield was 8.84 g or 27.2%, and the remaining fraction yield was 3.93 g or 12.1%. In conclusion, oil palm leaves are a prospective source of zingerol compounds, suggesting potential to be used as an alternative to rhizomes.
Co-Authors Adinda Dwina Hadiastuti Agung Sriyono Agustina, Ni Kadek Ayu Akbar, Nabila Hadiah Akhirullah, Muhammad Maulana Aldiana Astuti Alfisyahr, Nurul Hikmah Amalia Khairunnisa Amalia Khairunnisa Amalia Khairunnisa, Amalia Amalia Khirunnisa Amalia Risna Anna Khumaira Sari Anna Khumaira Sari Arnida Arnida Asa, Raudatul Jannah Audya Rahmah Bayu Bakti Angga Santoso Buih, Putri Helena Junjung Chatarina Umbul Wahyuni DENI SETIAWAN Dewi Kartika Dewi Kartika Dewi Ramadhani Difa Intannia DINA HARDIYANTI Dina Noor Kamali Edy Meiyanto Elma Stasya Endang Wahyuningsih Erika Nur Aisyah Fadlilaturrahmah Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fhirda Azhari Fitri Apriliany, Fitri Gema Yulan Dahnis Hayatun Izma Henni Selvina Henny Maryani Herningtyas Nautika Lingga Humairah Humairah Ikhwan Rizki, Muhammad Indah Hairunisa Izma, Hayatun Jauhar Latifah Khairunnisa Khoirunnisa Muslimawati Khumaira Sari, Anna Kurniasari, Winda Tri Laura Sarwo Liling Triyasmono Linda Permata Sari Malahayati, Siti Maslia Rahmah Maulidya Najahidin Melindawati, Vina Mia Fitriana Muhammad Ikhwan Rizki Muhammad Irfan Rosyadi Muhammad Itqan Mazdadi Muhammad Rasyid Ridha Muthi Ikawati Mutia Mawaddah Normilawati Nur Mahdi Nurramadhani A. Sida Nurul huda Nurul Mardiati Pratiwi, Endah Agustia Qory Rahmat Nazri Rahmah, Indah Noor Rahmah, Maslia Rahmat Ramadhani Rahmatullah, Satrio Wibowo Rahmawati, Nanda Hesti Ramadhani, Muhammad Irfan Ratna Asmah Susidarti Ratnapuri, Prima Happy Rezka Fajar Ramadhan Ricky Desrianto Risye Hendry Ronalisa Ronalisa Rosiana Aryani Rusdiana Rusdiana Samsul Hadi Samsul Hadi Saputra, Adryan Maulana Sholikhah Deti Andasari Silviana, Mega Sindwi Rinanda Sari Siti Nur Oktavia Sofia Sutomo Sutomo Sutomo Sutomo Syifa Auliani Syifa Auliani Sylvan Septian Ressandy Tangkas, Hansel Hens Viogenta, Pratika Wasilah Winsa Wira Wijaya Yopie Kusuma Kurniawan