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All Journal Farmaka Majalah Obat Tradisional INDONESIAN JOURNAL OF PHARMACY Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Pendas : Jurnah Ilmiah Pendidikan Dasar SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Kreativitas PKM JURNAL MITRA KENCANA KEPERAWATAN DAN KEBIDANAN JURNAL FARMASI GALENIKA Indonesian Journal of Pharmaceutical and Clinical Research Jurnal Riset Kefarmasian Indonesia Science Midwifery Jurnal Health Sains Jurnal Insan Farmasi Indonesia Reputasi: Jurnal Rekayasa Perangkat Lunak JURNAL PENDIDIKAN INDONESIA: Teori, Penelitian, dan Inovasi Bayani Sciences of Pharmacy Jurnal Farmasi Indonesia Sinergi International Journal of Management and Business Civilization Research: Journal of Islamic Studies Cendikia Pendidikan Zona Education Indonesia Advances in Applied Accounting Research Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Sains dan Kesehatan Proceeding Of International Conference On Education, Society And Humanity Jurnal Farmasi Galenika International Journal of Health, Medicine, and Sports Research Psychologie, Orientation et Conseil
Yani Mulyani
School of Pharmacy, Institute of Technology Bandung. Jl. Ganesa No. 10 Bandung
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Effects of Various Dietary Patterns on Total Cholesterol, Triglycerides, HDL, and LDL in Male Wistar Rats Mulyani, Yani; Kaniawati, Marita; Fajeri, Nur Iman
International Journal of Health, Medicine, and Sports Vol. 3 No. 4 (2025): International Journal of Health, Medicine, and Sports
Publisher : Corespub

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46336/ijhms.v3i4.272

Abstract

Atherosclerosis is a cardiovascular disorder characterized by lipid plaque buildup in arterial walls. Lipid profile is a critical factor in the risk of developing atherosclerosis and is strongly influenced by dietary patterns. This study aimed to investigate the effects of ketogenic, ketofastosis, and high-fat–high-carbohydrate (HFHC) diets on the lipid profile—including total cholesterol, triglycerides, HDL, and LDL—compared to a standard diet in male Wistar rats. Male Wistar rats were divided into four dietary groups: standard, ketogenic, ketofastosis, and HFHC. Each group was fed its respective diet for 30 days. On day 31, lipid profile parameters were measured using an automatic analyzer (COBAS C-311®), and body weight was also recorded. No significant differences were found in body weight or total cholesterol among the groups (p > 0.05). Both ketogenic and ketofastosis diets reduced triglyceride levels, with only the ketofastosis group showing a statistically significant reduction (p < 0.05). The HFHC diet increased triglyceride levels, though not significantly (p > 0.05). All three experimental diets significantly increased HDL levels (p < 0.05), with the ketofastosis diet showing the greatest effect. Additionally, all three diets significantly decreased LDL levels (p < 0.05). Ketogenic, ketofastosis, and HFHC diets positively affected lipid profiles by improving HDL and reducing LDL levels in Wistar rats. Among these, the ketofastosis diet demonstrated the most favorable lipid-modulating effects.
Article review: The role of probiotics in maintaining balance intestinal microbiota on diarrhea infection therapy Solihah, Nurlaella; Mulyani, Yani; Kaniawati, Marita
Science Midwifery Vol 13 No 5 (2025): December: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i5.2165

Abstract

Diarrhea infections are a significant global health problem, especially in developing countries and can be caused by bacterial, viral or parasitic infections. Antibiotics are often given times ineffective in long-term use and risk disrupting the balance of intestinal microbiota. So that probiotics are needed that come from living microorganisms that provide health benefits if consumed in sufficient quantities. Review This article aims to review the role of probiotics in maintaining the balance of intestinal microbiota and their effectiveness in diarrheal infection therapy. Through literature analysis, several probiotic strains such as Lactobacillus and Bifidobacterium have shown their ability to inhibit the growth of pathogens, such as Escherichia coli and Clostridium difficile, through nutrient competition, production of antimicrobial substances, and immune modulation. This article concludes that probiotics have great potential as an additional therapy that is safe, effective and has minimal side effects in treating diarrheal infections. However, further studies are needed to determine the optimal dose, duration of use, and effectiveness of probiotics in various populations and types of diarrhea.
The Impact of Habituation of Spiritual Activities on Social Attitudes and Behaviors of Observational Study Students at SD Muhammadiyah 3 Bandung Mulyani, Yani; Muyassar M, Raihan; Sholiehah, Nurul; Hadiantini, Dian; Rahmawati, Eti; Supala
Zona Education Indonesia Vol. 3 No. 6 (2025): December 2025
Publisher : Yayasan Mentari Madani

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The formation of social attitudes and behaviors among elementary school students requires sustainable and contextual character education strategies. One approach widely implemented in faith-based schools is the habituation of spiritual activities through daily religious routines. This study aims to describe the impact of habituated spiritual activities on students’ attitudes and social behaviors at SD Muhammadiyah 3 Bandung. The study employed a descriptive qualitative approach with an observational study design. Data were collected through participatory observation of students’ spiritual activities and documentation, including activity schedules, school regulations, and archives of religious programs. Data analysis was conducted thematically through data reduction, data display, and conclusion drawing. The findings indicate that the habituation of spiritual activities such as prayers before and after lessons, BTQ/Khas programs, muroja’ah, congregational Dhuha prayer, congregational Zuhur prayer, Qur’anic memorization (tahfidz AlQur’an), and the implementation of the 6S culture (Smile, Greeting, Salutation, Addressing, Politeness, and Courtesy) contributes positively to the development of students’ discipline, responsibility, and prosocial behavior. Scheduled worship routines encourage punctuality, compliance with rules, and more orderly social interactions among students. However, observational findings also suggest that the impact of spiritual habituation is not always linear in relation to students’ engagement in academic learning. Therefore, proportional management and continuous evaluation of spiritual habituation programs are necessary to ensure that character development benefits remain balanced with students’ academic learning needs. Keywords: spiritual habituation, social behavior, elementary school, student attitudes, observational study
Gambaran Pola Penggunaan Antipsikotik Pada Pasien Skizofrenia Di Ruang Rawat Inap Rumah Sakit Jiwa Provinsi Jawa Barat Sutrisno, Entris; Mulyani, Yani; Sodik, Jajang Japar
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 18 No 1 (2026): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v18i1.344

Abstract

Indonesia experiences an alarming increase in mental disorder cases annually. In 2019, the World Health Organization reported that over 20 million individuals worldwide suffer from schizophrenia. Antipsychotic medications are the preferred treatment option for schizophrenia, as they help alleviate psychotic symptoms and reduce the likelihood of developing the disorder. This study aimed to describe the use of antipsychotic drugs in patients with schizophrenia in the inpatient ward of the Mental Hospital of West Java Province. The study employed a non-experimental, descriptive design with retrospective data collection. Secondary data were used for analysis. The research focused on 194 medical records of patients who received antipsychotic treatment between January and December 2020. The study revealed that 56.19% of prescribed antipsychotic drugs were combination medications, while 43.81% were single drugs. The most common combination of antipsychotic drugs was haloperidol-clozapine, accounting for 36.60% of the prescriptions, and risperidone, a single drug, comprised 19.67% of the prescriptions.
EVALUATION OF THE QUALITY OF INDIVIDUAL LEARNING PROGRAMMES (PPI) BASED ON INTEGRATED QUALITY MANAGEMENT FROM THE PERSPECTIVE OF ITQAN VALUES: A SEQUENTIAL EXPLORATORY APPROACH AT SD PLUS AL GHIFARI Ruswandi, Uus; Muslikhin, Muslikhin; Sam'un, Sam'un; Mulyani, Yani; Baihaqi, Mohammad Aqil
Research Psychologie, Orientation et Conseil Vol. 3 No. 1 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/rpoc.v3i1.3166

Abstract

Inclusive education services through Individualized Education Programs (IEP) often struggle with administrative formalities lacking spiritual depth. This study aims to evaluate IEP quality by integrating Total Quality Management (TQM) and the value of Itqan as a solution for the desecularization of Islamic education management. Employing a mixed-methods sequential explanatory design at SD Plus Al Ghifari, data were collected via questionnaires from 66 respondents and in-depth interviews with key informants. Quantitative findings indicate that both TQM and Itqan significantly influence IEP quality, with Itqan providing a dominant contribution (0.528). Qualitative findings reveal that program effectiveness is driven by a culture of muraqabah (divine consciousness) and daily muhasabah (self-reflection), transforming professionalism into a form of worship. In conclusion, integrating transcendental dimensions into modern managerial systems creates a Spiritual Quality Management model that ensures precision and accountability for students with special needs. This study recommends internalizing Islamic work ethics as a primary catalyst for quality assurance in inclusive Islamic educational institutions.
Review article "antifungal activity of black garlic (allium sativum linn) extract against candida albicans fungus" Saifurrohman, Arip; Mulyani, Yani
Science Midwifery Vol 14 No 1 (2026): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2293

Abstract

This study aims to analyze the effectiveness of black garlic extract (Allium satium Linn) on the growth of candida albicans fungus, which is known as an opportunistic pathogen in humans, black garlic produced through the process of heating garlic contains active compounds such as allicin, saponins, flavonoids and tannins that have the potential as antifungals. The method used in this study is a narrative review based on articles published in the last 10 years. The results show that black garlic extract can inhibit the growth of C. Albicans with a significant inhibition zone diameter at certain concentrations. In addition, black garlic has higher antioxidant activity than fresh garlic, making it a safe and effective alternative in the treatment of fungal infections, especially in the context of increasing antifungal resistance. This study recommends the formulation of black garlic in the form of a gel preparation as a safer and more effective preparation for applications in pharmaceutical preparations.
PENGARUH TERAPI FARMAKOLOGI DAN NON-FARMAKOLOGI TERHADAP PENURUNAN NYERI MENSTRUASI PADA MAHASISWI FAKULTAS FARMASI UNIVERSITAS BHAKTI KENCANA BANDUNG Anggriani, Ani; Mulyani, Yani; Pratiwi, Lili Dinda
Jurnal Riset Kefarmasian Indonesia Vol. 3 No. 3 (2021): Jurnal Riset Kefarmasin Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v3i3.156

Abstract

Menstrual pain is a problem that women often complain about in their teens. Menstrual pain (dysmenorrhea) is pain before or during menstruation in the lower abdomen due to uterine cramps. The prevalence of dysmenorrhea in Indonesia is 54% primary dysmenorrhea and 9% secondary dysmenorrhea. Due to the severe pain that is felt during menstruation, 10% of teenage girls are absent from school and work for 3 days each month. This study aims to determine the effect of pharmacological & non-pharmacological therapy on reducing menstrual pain in adolescents. This research is an experimental research with one group pretest-post test design. The research sample used purposive sampling method, with a sample of 76 respondents. Data were analyzed using the Wilcoxon Signed Rank Test & chi-square test. The results showed that the Wilcoxon test with the results of Sig. 0.000<0.05, meaning that there is a difference in the intensity of menstrual pain before & after therapy. So it can be concluded that there is an effect of pharmacological and non-pharmacological therapy on decreasing the intensity of menstrual pain. For the relationship of non-pharmacological therapy Chi-Square test results have a value of Sig. 0.514>0.05, meaning that there is no significant relationship to the intensity of menstrual pain. For the relationship between pharmacological therapy, the results of Sig. 0.019<0.05, meaning that there is a significant relationship with the intensity of menstrual pain in adolescent girls at Bhakti Kencana University, Bandung.
Antidiabetic and Antidyslipidemic Activity of Ethyl Acetate Fraction of Binahong Leaves in Streptozotocin (STZ)-induced Diabetic Rats Mulyani, Yani; Hasimun, Patonah; Apriliyanti, Nida Putri
Majalah Obat Tradisional Vol 31, No 1 (2026)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.100960

Abstract

Diabetes mellitus (DM) is a disease characterized by hyperglycemia and impaired glucose, protein, and fat metabolism due to insulin deficiency or resistance. In type 2 DM, insulin resistance potentially causes dyslipidemia through increased lipolysis and glucose production in the liver as well as reduced glucose absorption into cells. According to previous reports, the prevalence of dyslipidemia is relatively high, ranging from 72-85%. One of the plants that has the potential for antidiabetic and antidyslipidemic is binahong (Anredera cordifolia (Ten.) Steenis). Therefore, this research aims to determine the antidiabetic and antidyslipidemic activity as well as the effective dose of ethyl acetate fraction from ethanol extract of binahong leaves to reduce blood sugar levels, total cholesterol, triglycerides, LDL, IAP, increase HDL levels, and improve the histological profile of the pancreas and aorta. The experiment was conducted curatively using 30 rats divided into 5 treatment groups, namely normal (Na-CMC 0.5%), diabetic group (Streptozotocin 35 mg/kgBW), positive control (Simvastatin 10 mg/kgBW), and the test group given ethyl acetate fraction of ethanol extract at dose 1 (100 mg/kgBW) and 2 (150 mg/kgBW). All groups except normal received streptozotocin induction for 3 days until a diabetic rat model was formed, then the test drug treatment was given for 28 days. Blood sugar levels were measured on days 0, 3, 14, and 28 using a glucometer, and lipid profile levels were measured on days 0 and 28 enzymatically using a microlab 300. The results showed that the ethyl acetate fraction of binahong leaves ethanol extract at a dose of 100 mg/kgBW demonstrated antidiabetic and antidyslipidemic effects. It reduced blood glucose and lipid levels by 36–62% compared to the diabetic group and showed similar results to the positive control. This dose also improved the histological structure of the pancreas and aorta.
Co-Authors Adang Hambali, Adang Agus Sulaeman Aligita, Widhya Amini, Nadia Ushfuri Ani Anggriani, Ani Apriliyanti, Nida Putri Assalam, Sunan Hanif Ihsan Bachrudin, Panji Badrudin Bagus Suryadi, Bambang Baihaqi, Mohammad Aqil Bambang Kelana Simpony Choirunnisa, Zulfy Davronov, Istamkhuja Olimovich dirgahayu, inggrid Elin Yulinah Embas Saraswati, Dewa Ayu Eti Rahmawati Fajeri, Nur Iman Garnadi Jafar, Garnadi Hadiantini, Dian Hasan Basri Hasimun, Patonah Hidayat, Abdilah Alam Hernan I Gusti Agung Ayu Hari Triandini I Ketut Adnyana Ika Kurnia Sukmawati Ilham Suparman, Muhamad Iskandar Jioe, Yulius Isvahanie, Salsha Rifa Jajang Jafar Sodik Jajang Japar Sodik Jamaludin . Khotimah, Nur Intan Husnul Kurnia Sukmawati, Ika Kurniasih, Imas Marita Kaniawati Maulana, Rizka Husnu Melysa, Melysa Muhtadin Mukhlishah Muslikhin Muyassar M, Raihan Mu’atawakil, Raihan Muyassar Nopriyanti, Selly Nugraha, Budy Nugraha, Eka Rahmat Nurswardiana, Hanna Pasha, ED. Yunisa Mega Patonah, Patonah Pratiwi, Lili Dinda Prawestyi, Poety Putriyanti, Al-fira Rahayu, Sri Mulyati Rofi Fahmi, Dede Ruswandi, Uus Saifurrohman, Arip Salam, Mochamad Fadlani Sam'un, Sam'un Sapitri, Wina Sari, Mela Mustika Sholiehah, Nurul Siti Balqis, Salwa Siti Saidah Solihah Sari Rahayu Solihah, Nurlaella Sriwantika, Ika Sumarna, Rendi Supala Sutrisno, Entris Tambunan, Irisanna Utami, Pujani Vitniawati, Vina