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EFFECTIVENESS OF THE MERDEKA TEACHING PLATFORM (PMM) AS A MEDIA FOR TEACHER PROFESSIONAL DEVELOPMENT IN DRIVE SCHOOLS Mulyani, Yani; Maulana, Rizka Husnu; Badrudin, Badrudin
PROCEEDING OF INTERNATIONAL CONFERENCE ON EDUCATION, SOCIETY AND HUMANITY Vol 2, No 2 (2024): Third International Conference on Education, Society and Humanity
Publisher : PROCEEDING OF INTERNATIONAL CONFERENCE ON EDUCATION, SOCIETY AND HUMANITY

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This research aims to analyze the effectiveness of the Merdeka Mengajar Platform (PMM) as a medium for developing teacher professionalism in Sekolah Penggerak. The study was conducted in several Sekolah Penggerak in the Sindangwangi District of Majalengka Regency, involving teachers and school principals as the main participants. A qualitative approach with a case study method was used to explore in-depth data related to the experiences, perceptions, and impact of PMM usage on teacher professional competence. The research findings indicate that PMM significantly contributes to supporting the development of pedagogical and managerial competencies of teachers, especially through its integrated continuous development features. However, its effectiveness is influenced by factors such as technology access, user motivation, and school institutional support. This research recommends strengthening PMM usage training and improving supporting infrastructure to optimize the benefits of this platform in supporting the Sekolah Penggerak program
Ethyl Acetate Fraction of Gynura procumbens Mitigates Hyperglycemia, Dyslipidemia, and Tissue Damage in Streptozotocin-Induced Diabetic Rats Mulyani, Yani; Kaniawati, Marita; Aligita, Widhya; Nugraha, Eka Rahmat
Sciences of Pharmacy Volume 4 Issue 4
Publisher : ETFLIN Publishing House

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0404371

Abstract

Dyslipidemia is a lipid metabolism disorder frequently associated with diabetes mellitus and known to increase cardiovascular risk. Although Gynura procumbens has been reported to possess antidiabetic and antidyslipidemic properties, studies focusing on the specific effects of its ethyl acetate fraction remain limited. This study investigated the therapeutic potential of the ethyl acetate fraction of ethanol extract from G. procumbens in streptozotocin-induced diabetic rats, particularly its impact on blood glucose, lipid profiles, and histological changes in pancreatic and aortic tissues. Thirty rats were randomly assigned to six groups: normal control, diabetic control, glibenclamide, simvastatin, and extract-treated groups at 100 and 150 mg/kg body weight. After 28 days of treatment, the 150 mg/kg dose significantly reduced blood glucose by 61.3%, total cholesterol by 42.1%, triglycerides by 47.3%, and LDL by 55.0%, while increasing HDL by 6.3% compared to diabetic control (p < 0.05). Histological analysis demonstrated regeneration of pancreatic β-cells and improvement of vascular structure in the aorta. These findings suggest that the ethyl acetate fraction of G. procumbens may serve as a promising natural agent for managing diabetes and dyslipidemia.
ZUHUD DAN GAYA HIDUP BERKELANJUTAN MENURUT TINJAUAN SUFISTIK DAN PSIKOLOGI ISLAM Mulyani, Yani; Rahayu, Solihah Sari; Jamaludin, Jamaludin
Jurnal Pendidikan Indonesia : Teori, Penelitian, dan Inovasi Vol 5, No 5 (2025): Jurnal Pendidikan Indonesia : Teori, Penelitian, dan Inovasi
Publisher : Penerbit Widina, Widina Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59818/jpi.v5i5.1956

Abstract

Zuhud is not merely understood as physical detachment from worldly possessions but rather as an inner release from excessive dependence on material pleasures. In the context of modern life, which is dominated by materialism and consumerism, zuhud provides an alternative conscious lifestyle that balances worldly needs with ultimate spiritual goals. This article aims to examine the concept of zuhud within classical Sufi traditions and to explore its relevance to sustainable living in contemporary society. The study employs a library research method with Sufi and Islamic psychological (nafsiyological) approaches. The findings reveal that zuhud encompasses significant spiritual, psychological, and social dimensions. Spiritually, zuhud fosters transcendental awareness; psychologically, it contributes to self-control and mental well-being; and socially, it promotes simplicity, solidarity, and sustainability in resource utilization. Thus, zuhud can be recontextualized as an ethical and spiritual framework to address the value crisis, psychological pressures, and ecological challenges of modern society.ABSTRAKZuhud tidak sekadar dimaknai sebagai sikap menjauhi dunia secara fisik, tetapi lebih pada pelepasan ketergantungan batin terhadap kenikmatan materi yang berlebihan. Dalam konteks kehidupan modern yang sarat dengan materialisme dan konsumerisme, nilai-nilai zuhud menghadirkan alternatif gaya hidup berkesadaran yang mampu menyeimbangkan kebutuhan duniawi dan ukhrawi. Artikel ini bertujuan untuk mengkaji konsep zuhud dalam tradisi tasawuf klasik serta mengeksplorasi relevansinya terhadap gaya hidup berkelanjutan di era kontemporer. Penelitian menggunakan metode studi pustaka dengan pendekatan sufistik dan psikologi Islam (nafsiyologis). Hasil kajian menunjukkan bahwa zuhud memiliki dimensi spiritual, psikologis, dan sosial yang signifikan. Pada dimensi spiritual, zuhud menumbuhkan kesadaran transendental; pada dimensi psikologis, ia berkontribusi dalam pengendalian nafsu serta kesehatan mental; dan pada dimensi sosial, ia mendorong pola hidup sederhana, solidaritas, serta keberlanjutan dalam pemanfaatan sumber daya. Dengan demikian, zuhud dapat direkontekstualisasikan sebagai kerangka etis dan spiritual untuk menghadapi krisis nilai, tekanan psikologis, dan tantangan ekologis masyarakat modern.
Analisis Efektivitas Biaya Pengobatan Medis pada Pasien Glaukoma Primer Sudut Terbuka dengan Kombinasi Obat Latanoprost-Betaxolol dengan Latanoprost-Timolol di Rumah Sakit Mata Cicendo: Analysis of the Cost Effectiveness of Medical Treatment in Patients with Primary Open-Angle Glaucoma Treated with a Combination of Latanoprost-Betaxolol and Latanoprost-Timolol at Cicendo Eye Hospital Utami, Pujani; Saidah, Siti; Mulyani, Yani
Jurnal Sains dan Kesehatan Vol. 7 No. 6 (2025): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v7i6.2553

Abstract

Glaucoma is the second leading cause of blindness after cataracts and is permanent. Glaucoma therapy involves the use of prostaglandin analogues, adrenergic blocking agents, or a combination of both. Various therapeutic issues related to cost have been identified when considering combination drugs and their effectiveness. This study aims to determine the use of glaucoma drugs combination medications that are most cost-effective for patients at Cicendo Eye Hospital using latanoprost, latanoprost+betaxolol, and latanoprost+timolol. The study design is a retrospective descriptive observational study with a pharmacoeconomic analysis approach using outpatient medical records. The most commonly used combination medications belongs to the prostaglandin analog and adrenergic blocking agent class, namely latanoprost+timolol (74.51%), latanoprost+betaxolol (17.65%), and latanoprost (7.84%). The combination of latanoprost+timolol 0.5% is considered the most cost-effective therapy for Open-Angle Glaucoma with an ACER value of Rp 11,853 and an ICER of Rp 41,003.58. Keywords:          Cost-Effectiveness Analysis, Glaucoma, Combination Drugs   Abstrak Glaukoma merupakan penyebab kebutaan kedua terbanyak setelah katarak dan bersifat permanen. Terapi glaukoma adalah dengan pengobatan golongan analog prostaglandin, adrenergic blocking agent, termasuk kombinasi keduanya. Ditemukan berbagai permasalahan terapi terkait sisi biaya dengan melihat obat kombinasi dan keefektifannya. Penelitian ini bertujuan untuk mengetahui penggunaan obat glaucoma kombinasi yang paling cost-effective pada pasien di RS Mata Cicendo dengan terapi latanoprost, latanoprost+betaxolol, latanoprost+timolol. Desain penelitian ini adalah observasi retrosfektif deskriptif  dengan pendekatan analisis farmakoekonomi dari data rekam medik pasien rawat jalan. Obat kombinas yang paling banyak digunakan adalah golongan Analog prostaglandin & adrenergic blocking agent yaitu latanoprost+timolol (74,51%), latanoprost+betaxolol (17,65%) dan latanoprost (7,84%). Kombinasi latanoprost+timolol 0,5%  dinilai sebagai terapi paling cost-effective untuk Glaukoma Sudut Terbuka dengan nilai ACER sebesar Rp 11.853 dan ICER Rp 41.003,58. Kata Kunci:         Analisis Efektifitas Biaya, Glaukoma, Obat kombinasi
Analisis Hubungan Polifarmasi Dengan Potensi Interaksi Obat Pada Peresepan Pasien Diabetes Melitus Tipe 2 Mulyani, Yani; Siti Balqis, Salwa; Sutrisno, Entris; Anggriani, Ani
JURNAL FARMASI GALENIKA Vol 11 No 2 (2024): Jurnal Farmasi Galenika Vol 11 No 2
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v11i2.332

Abstract

The IDF estimates that the prevalence of diabetes mellitus based on age will continue to increase from 2021 to 2045 (24.0% vs 24.7%). Patients with diabetes mellitus have comorbidities that result from elevated blood glucose levels, leading to polypharmacy and potential drug interactions. This study aims to determine the percentage of drug interactions and the relationship between polypharmacy and the potential for drug interactions in patients with type 2 diabetes mellitus at RSU Rama Hadi Purwakarta. The study was conducted using a cross-sectional, retrospective method, analyzing prescriptions of patients with type 2 diabetes mellitus at RSU Rama Hadi from September 1 to 30, 2022. Prescriptions were identified for interaction types and severity using drugs.com, Medscape, and Stockley's Drug Interaction Handbook, 9th edition, with results analyzed using Fisher's exact test. The study found that patients aged 56-65 years (40.1%) were more likely to suffer from type 2 diabetes mellitus, with females having a higher incidence compared to males (70.7% vs 29.3%). Among 147 prescriptions, 97% had drug interactions, with moderate severity predominating (97.8%), and pharmacodynamic interactions being the most common (76%). Fisher's exact test revealed a p-value of 0.001 (p < 0.005). Thus, it can be concluded that there is a significant relationship between polypharmacy and the potential for drug interactions in the prescriptions of type 2 diabetes mellitus patients at the pharmacy department of RSU Rama Hadi Purwakarta.
Review of medication therapy management provided by pharmacists to hypertension and diabetes patients in Indonesia Nurswardiana, Hanna; Mulyani, Yani; Patonah, Patonah
Science Midwifery Vol 12 No 2 (2024): June: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v12i2.1596

Abstract

Non-communicable diseases (NCDs) cause around 74% of deaths in the world, two of which are caused by hypertension and diabetes, which are chronic diseases. In general, it is characterized by high morbidity, polypharmacy and long-term treatment. This causes poor treatment compliance in the majority of respondents and has an impact on increasing disease complications, morbidity, mortality and treatment costs. Pharmacist intervention in managing NCDs has developed through a systematic, comprehensive medication management model approach such as the Medication Therapy Management (MTM) approach. This MTM model is designed to improve clinical outcomes from therapy, increase appropriate drug use, resolve treatment-related problems, improve respondents' quality of life and can provide good efficiency in avoiding risk factors for disease complications. This review was prepared to serve as comprehensive reference material regarding PTM. The method used is collecting scientific articles from national and international sources. The results obtained show that the MTM approach is an excellent pharmacist practice model in providing comprehensive pharmaceutical services for NCDs, especially hypertension and diabetes. The interventions that pharmacists can provide are comprehensive counseling by evaluating clinical results, compliance, knowledge, quality of life, perception of illness.
Literature study: Relationship between pharmacist's "pharmaceutical care" and achievement of blood pressure targets in hypertension patients Sriwantika, Ika; Mulyani, Yani; Patonah, Patonah
Science Midwifery Vol 12 No 3 (2024): August: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v12i3.1615

Abstract

Hypertension is defined by persistently elevated arterial blood pressure. The Seventh Report of the Joint National Committee (JNC VII) on Detection, Evalution, and Treatment of High Blood Pressure explains that hypertension is a condition where there is an increase in blood pressure in the arteries above 140/90 mmHg. The general goal of hypertension treatment is to reduce mortality and morbidity associated with hypertension. Mortality and morbidity are related to target organ damage. Reducing risk is the main goal of hypertension therapy, and the choice of drug therapy is significantly influenced by evidence showing risk reduction. The target blood pressure value recommended in JNC VII for most patients is < 140/90 mm Hg, patients with diabetes < 130/80 mm Hg and patients with chronic kidney disease < 130/80 mm Hg. One part of the therapeutic management of hypertensive patients to achieve therapeutic goals is through pharmaceutical care (Pharmaceutical care). Counseling as an implementation of the concept of pharmaceutical care (pharmaceutical care) aims to provide additional knowledge about drugs and treatment with the hope of providing patients with an understanding of the role of drugs in curing their disease. This review summarizes the results of research on the effect of pharmacist intervention on achieving blood pressure targets for hypertensive patients by searching international and national published scientific journals from the last year 2010- 2021 via electronic databases in the form of Pubmed, ScienceDirect and Google Scholar.
Sistem Informasi Penerimaan Peserta Didik Baru Pada SMK MA’ARIF NU Banjarsari Kabupaten Ciamis Berbasis Web Mulyani, Yani; Kelana Simpony, Bambang; Ilham Suparman, Muhamad
Reputasi: Jurnal Rekayasa Perangkat Lunak Vol. 4 No. 2 (2023): November 2023
Publisher : LPPM Universitas Bina Sarana Informatika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31294/reputasi.v4i2.2463

Abstract

Teknologi memegang peranan penting dalam mendukung kegiatan pembelajaran. Misalnya dengan adanya teknologi dapat mempermudah proses belajar mengajar karena siswa dapat dengan mudah mengakses internet, informasi pendidikan dari berbagai sumber juga tersedia untuk memperluas wawasan siswa dan guru. SMK Ma’arif NU Banjarsari meliputi informasi mengenai sekolah dan PPDB (Penerimaan Peserta Didik Baru), PPDB adalah salah satu agenda tahunan penerimaan murid di setiap jenjang sekolah metode pendaftaran sekolah melalui daring, sedangkan PPDB di SMK Ma’arif NU Banjarsari belum terkomputerisasi masih dilakukan secara manual yang mengharuskan calon siswa dan siswi mendatangi sekolah untuk mendaftar. Tujuan dari penelitian ini adalah mempermudah tenaga pendidik dalam mendata calon siswa, meningkatkan pengetahuan tenaga pendidik dan calon siswa dalam bidang teknologi khusus PPDB Online, mempermudah calon siswa dalam mengisi PPDB, mengenalkan teknologi kepada tenabga pendidik, calon siswa dan orang tua siswa serta masyarakat luas tentang PPDB Online. Metode penelitian ini menggunakan Rapid Application Development (RAD) atau rapid prototyping adalah model proses pembangunan perangkat lunak yang tergolong dalam teknik inkremental (bertingkat). Hasil dari penelitian ini menghasilkan website PPDB SMK Ma’arif NU Banjarsari sehingga memudahkan tenaga pendidik dalam mendata calon siswa yang terdaftar serta memudahkan calon siswa dan orang tua siswa dalam menginput data untuk mendaftar.
Edukasi Program A, B, C, D, E, Cegah Stunting Menyiapkan Generasi Unggul, Berdaya Saing Sejak Masa Kandungan pada Kader Kota Bandung Sutrisno, Entris; Mulyani, Yani; Rahayu, Sri Mulyati; Vitniawati, Vina; Darajat, Agus Miraj; Amini, Nadia Ushfuri; Pasha, ED. Yunisa Mega; Khotimah, Nur Intan Husnul
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 7, No 3 (2024): Volume 7 No 3 2024
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v7i3.12814

Abstract

ABSTRAK Generasi unggul dan berdaya saing merupakan visi Indonesia, sehingga pemberantasan stunting merupakan target utama dalam upaya pencapaian visi ini.  Stunting berdampak merugikan pada anak karena dapat menyebabkan lambatnya perkembangan otak (kognitif), fisik dan risiko serangan penyakit, hal ini akan berefek pada masyarakat secara umum sehingga penting untuk ditangani. Tujuan Program pengabdian masyarakat ini adalah meningkatkan pengetahuan pada kader dalam menyiapkan generasi unggul dan berdaya saing dengan pencegahan stunting sejak dini dari masa kandungan. Metode Pelaksanaan pengabdian masyarakat program edukatif dengan menggunakan penyuluhan (Pendidikan Kesehatan) guna meningkatkan pengetahuan kader. Adanya program ini dapat meningkatkan pengetahuan kader bagaimana mencegah stunting sejak dalam masa kandungan. Kader dapat menerapkan Langkah pencegahan stunting dan selanjutnya mensosialisasikan pada masyarakat umum tentang (A) Aktif minum Tablet Tambah Darah (TTD), (B) Bumil teratur periksa kehamilan minimal 6 kali, (C) Cukupi konsumsi protein hewani, (D) Datang ke Posyandu setiap bulan, (E) Eksklusif ASI 6 bulan. Dengan pemahaman tentang ABCDE diharapkan dapat menciptakan Generasi unggul berdaya saing yang Sehat dan Bebas dari Stunting. Program ini berhasil dalam meningkatkan pengetahuan kader tentang cegah stunting dengan ABCDE, sehingga disarankan agar kader dapat ikut serta dalam mempromosikannya kepada masyarakat dan dapat mengurangi kejadian stunting. Kata Kunci: Stunting, Kader, Generasi Unggul, ABCDE  ABSTRACT A superior and competitive generation is Indonesia's vision, so eradicating stunting is the main target in efforts to achieve this vision. Stunting has a detrimental impact on children because it can cause slow brain (cognitive) and physical development and the risk of disease attacks, this will have an impact on society in general so it is important to address it. This community service program is to increase knowledge among cadres in creating a superior and competitive generation by preventing stunting from an early age from the womb. Method of implementing community service: educational program using counseling (Health Education) to increase cadres' knowledge. This program can increase cadres' knowledge of how to prevent stunting from the womb. Cadres can implement steps to prevent stunting and further socialize to the general public about (A) Actively drinking Blood Supplement Tablets (TTD), (B) Pregnant women regularly having pregnancy checks at least 6 times, (C) Sufficient consumption of animal protein, (D) Coming to the Posyandu every month, (E) Exclusive breast milk for 6 months. By understanding ABCDE, it is hoped that we can create a superior, competitive generation that is healthy and free from stunting. This program was successful in increasing cadres' knowledge about stunting prevention with ABCDE, so it is recommended that cadres can participate in promoting it to the community and can reduce the incidence of stunting. Keywords: Stunting, Cadre, Superior Generation, ABCDE
Antimicrobial Activities and Mechanism of Action of Petiveria alliacea Stem Extract Mulyani, Yani; Ika Kurnia Sukmawati; Jajang Jafar Sodik
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 1 No. 1 (2018): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1106.564 KB) | DOI: 10.32734/idjpcr.v1i1.209

Abstract

Abstract. This research aimed to determine the antimicrobial activity of ethanol extract of Petiveria alliacea stem (EEPS) against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Candida albicans. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined by perforation and broth micro dilution methods. Study on the mechanism of action of EEPS was conducted by molecular docking and Scanning Electron Microscopy (SEM) techniques. The results showed that EEPS had an inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Candida albicans with MIC values of 256, 128, 256, 512 µg/ml, consecutively. These values are included in to the medium category. Through the process of molecular docking, the best interaction was observed between S-benzyl-L-cysteine sulfoxide with penicillin-binding protein receptor of Pseudomonas aeruginosa characterized by free energy change (ΔG) of 4.32 kcal/mol, and the Ki value of 682.16 μM. Four folds of MIC of the EEPS caused changes in the morphology of Pseudomonas aeruginosa. EEPS possessed antimicrobial activities against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Candida albicans. Keywords: Antimicrobial Activity, Molecular Docking, Petiveria alliacea, SEM.