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All Journal Farmaka INDONESIAN JOURNAL OF PHARMACY Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Pendas : Jurnah Ilmiah Pendidikan Dasar SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Kreativitas PKM JURNAL MITRA KENCANA KEPERAWATAN DAN KEBIDANAN JURNAL FARMASI GALENIKA Indonesian Journal of Pharmaceutical and Clinical Research Jurnal Riset Kefarmasian Indonesia Science Midwifery Jurnal Health Sains Jurnal Insan Farmasi Indonesia Reputasi: Jurnal Rekayasa Perangkat Lunak JURNAL PENDIDIKAN INDONESIA: Teori, Penelitian, dan Inovasi Bayani Sciences of Pharmacy Sinergi International Journal of Management and Business Civilization Research: Journal of Islamic Studies Cendikia Pendidikan Zona Education Indonesia Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Sains dan Kesehatan Proceeding Of International Conference On Education, Society And Humanity Jurnal Farmasi Galenika International Journal of Health, Medicine, and Sports
Yani Mulyani
School of Pharmacy, Institute of Technology Bandung. Jl. Ganesa No. 10 Bandung
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AKTIVITAS ANTIINFEKSI EKSTRAK ETANOL TANAMAN FAMILI ASTERACEAE TERHADAP BAKTERI DAN JAMUR PATOGEN Mulyani, Yani; Kurnia Sukmawati, Ika; Bagus Suryadi, Bambang
JURNAL FARMASI GALENIKA Vol 7 No 1 (2020): Jurnal Farmasi Galenika Volume 7 No. 1
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v7i1.172

Abstract

Penyakit infeksi merupakan salah satu permasalahan kesehatan khususnya di negara berkembang dan terus meningkat dari tahun ke tahun. Peningkatan ini dikarenakan adanya resistensi obat, peningkatan infeksi oportunistik, dan infeksi jamur sistemik sehingga diperlukan alternatif baru untuk menanggulangi penyakit tersebut, salah satunya dengan penggunaan obat dari bahan alam yaitu tanaman famili Asteraceae. Famili Asteraceae sudah banyak digunakan secara tradisional di Kalimantan sebagai obat luka, selain itu banyak penelitian mengenai kajian aktivitas antimikroba dan kandungan senyawa aktif antimikroba yang terdapat pada tanaman tersebut. Penelitian ini bertujuan untuk mengetahui aktivitas tanaman famili Asteraceaeyaitu insulin, sambung nyawa, bandotan, sembung dan afrika terhadap bakteri Escherichia coli, Salmonella thypi, Vibrio cholera, Staphylococcus aureus, Streptococcus pyogenes, Bacillus cereus, dan jamur Candida albicans, Trichophyton mentagrophytes, Microsporum gypseum, Aspergillus niger, Microsporum canis, dan Malassezia furfur. Pengujian dilakukan dengan menentukan konsentrasi hambat minimum (KHM) dari ekstrak etanol daun dari kelima tanaman tersebut dengan metode difusi agar. Studi lanjut dilakukan dengan menentukan aktivitas antijamur dari ekstrak dengan KHM terbaik dengan melihat kurva pertumbuhan yang diperoleh dari penentuan time killing. Hasil menunjukkan bahwa ekstrak dengan aktivitas terbaik adalah ekstrak daun afrika terhadap jamur Trichophyton mentagrophytes (KHM = 0,025 mg/mL) dan terhadap bakteri Streptococcus pyogenes (KHM 0,75 mg/mL). Berdasarkan pengujian time killing, ekstrak tersebut memiliki aktivitas bakteriostatik dan fungistatik sampai konsentrasi 8 KHM.
KEKAKUAN ARTERI PADA HIPERTENSI YANG DIINDUKSI L-NAME Hasimun, Patonah; Mulyani, Yani; Choirunnisa, Zulfy
JURNAL FARMASI GALENIKA Vol 8 No 3 (2021): Jurnal Farmasi Galenika Vol 8 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v8i3.197

Abstract

Latar belakang: Hipertensi merupakan salah satu faktor risiko penyakit kardiovaskular. Prevalensi hipertensi di dunia sekitar 15-20% yang diperkirakan akan terus meningkat. Telah dilaporkan bahwa kegagalan kontrol hipertensi dengan obat disebabkan karena ketidakmampuan obat dalam memperbaiki kekakuan arteri walaupun mencapai target penurunan tekanan darah. Model hewan diperlukan untuk mempelajari mekanisme patofisiologi dan target obat untuk mengatasi hipertensi dan kekakuan arteri. Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruh pemberian L-NAME terhadap tekanan darah, kekakuan arteri dan kadar NO (nitrit oksida). Metode: Penelitian ini dilakukan pada tikus Wistar jantan sebanyak 10 ekor dibagi secara acak menjadi 2 kelompok yang terdiri dari kelompok normal, kelompok induksi (L-NAME 40 mg/kg). Parameter yang diukur secara non invasif dan in vitro untuk mengetahui kadar NO pada serum. Hasil: Induksi L-NAME 40 mg/kg selama 28 hari meningkatkan tekanan darah, kekakuan arteri, menurunkan kadar NO serum yang berbeda bermakna terhadap kelompok normal. Kesimpulan: L-NAME menginduksi hipertensi yang disertai dengan kekakuan arteri.
REVIEW : PERBANDINGAN ANTARA TERAPI ANTIBIOTIK LEVOFLOXACIN JANGKA PENDEK DOSIS TINGGI DENGAN DOSIS REGIMEN KONVENSIONAL PADA PASIEN PNEUMONIA Putriyanti, Al-fira; Mulyani, Yani; Isvahanie, Salsha Rifa
Farmaka Vol 22, No 3 (2024): Farmaka (November)
Publisher : Fakultas Farmasi, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/farmaka.v22i3.56684

Abstract

Pneumonia merupakan infeksi saluran pernapasan bawah yang menyebabkan inflamasi pada alveoli paru-paru. Penyebab pneumonia salah satunya oleh bakteri streptococcus pneumoniae. Pengobatan yang tepat dan cepat sangat penting untuk mengurangi morbiditas dan mortalitas yang terkait dengan penyakit ini. Pengobatan pneumonia bakterial sering melibatkan penggunaan antibiotik, dengan levofloxacin sebagai salah satu pilihan utama karena spektrum aktivitasnya yang luas. Namun, durasi optimal terapi antibiotik masih menjadi perdebatan, apakah terapi jangka pendek atau jangka panjang lebih efektif dalam mempercepat pemulihan pasien. Penelitian ini bertujuan untuk membandingkan efektivitas terapi antibiotik levofloxacin jangka panjang dan jangka pendek dalam masa waktu pemulihan pasien dengan pneumonia bakterial. Data dari berbagai studi klinis dan penelitian observasional dari tahun 2014 hingga 2024 dianalisis untuk mengevaluasi durasi optimal terapi dalam hal penyembuhan klinis, risiko kekambuhan, dan pengembangan resistensi antibiotik. Hasil penelitian menunjukkan bahwa terapi jangka pendek seringkali sama efektifnya dengan terapi jangka panjang dalam mencapai penyembuhan klinis, dengan keuntungan tambahan berupa pengurangan risiko efek samping dan resistensi antibiotik. Namun, terapi jangka panjang mungkin diperlukan untuk kasus dengan keparahan lebih tinggi atau komorbiditas tertentu untuk memastikan eradikasi patogen sepenuhnya. Temuan ini mengindikasikan bahwa durasi terapi antibiotik harus disesuaikan dengan kondisi klinis spesifik pasien untuk mencapai hasil optimal.
Inquiry-Based Learning Strategy As An Effort To Increase Learning Interest In ISMUBA At MI Muhammadiyah 2 Bandung Mulyani, Yani; Mu’atawakil, Raihan Muyassar; Hidayat, Abdilah Alam Hernan; Salam, Mochamad Fadlani
Civilization Research: Journal of Islamic Studies Vol 4 No 2 (2025): Civilization Research: Journal of Islamic Studies
Publisher : PT. Student Rihlah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61630/crjis.v4i2.113

Abstract

This research aims to describe the implementation of the Inquiry-Based Learning (IBL) strategy, analyze teachers' and students' perceptions, and identify supporting and inhibiting factors in increasing learning interest in ISMUBA at MI Muhammadiyah 2 Bandung. A qualitative approach was used, with data collected through in-depth interviews, observations, and documentation involving ISMUBA teachers, students in grades 4–6, and the principal. The results show that IBL was implemented through discussions, case studies, role-playing, and field practice, creating an active, contextual, and enjoyable learning environment. Teachers and students had positive perceptions, feeling more enthusiastic, confident to express opinions, and better understanding Islamic teachings and Muhammadiyah history. Supporting factors include school management support, teacher competence, and a collaborative school culture, while inhibiting factors involve limited modules, varied student characteristics, time constraints, and limited facilities. The novelty lies in applying IBL to ISMUBA by integrating Islamic and Muhammadiyah values, and the implication is to strengthen value-based active learning policies to develop noble-character Muhammadiyah cadres.
Kajian Etnofarmakologi Pemanfaatan Tanaman Obat Oleh Masyarakat Di Kecamatan Dawuan Kabupaten Subang Provinsi Jawa Barat: Ethnopharmacology Study of utilization medicinal plant by Society in Dawuan sub-district Subang Regency West Java Province Mulyani, Yani; Hasimun, Patonah; Sumarna, Rendi
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 6 No. 1 (2020): (March 2020)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (672.716 KB) | DOI: 10.22487/j24428744.2020.v6.i1.13572

Abstract

Barat bertujuan untuk mengetahui jenis-jenis tumbuhan yang berkhasiat sebagai obat tradisional, bagian tumbuhan yang dapat digunakan sebagai bahan dalam pengolahan obat tradisional, cara menyiapkan, dosis yang digunakan dan cara menggunakan dalam pengobatan tradisional. Metode penelitian yang digunakan adalah survei eksploratif dan metode observatif, melalui wawancara semi-struktural dengan 81 responden menggunakan kuesioner yang meliputi nama penyakit, nama lokal tanaman, bagian tanaman yang dimanfaatkan, lokasi tumbuh dan cara membuatnya. Setiap tanaman yang digunakan untuk pengobatan dideterminasi dan dibuat herbarium. Hasil penelitian menunjukkan tanaman obat yang dimanfaatkan oleh masyarakat dan berhasil dideterminasi di Kecamatan Dawuan terdapat 40 spesies tanaman obat dari 27 famili. Famili Euforbiaceae merupakan tanaman yang paling banyak digunakan, dengan tingkat pengetahuan masyarakat tentang pemanfaatan obat sangat baik. Tanaman obat paling banyak digunakan berasal dari kebun dari bagian daun , dengan proses pengolahan dengan cara direbus dengan air dan digunakan dengan cara diminum
INTERNALISASI NILAI-NILAI MARDHATILLAH DALAM PEMBENTUKAN KARAKTER SISWA DI SD IT ALAM GARUT Sapitri, Wina; Mulyani, Yani; Rofi Fahmi, Dede; Assalam, Sunan Hanif Ihsan; Hambali, Adang; Basri, Hasan
Pendas : Jurnal Ilmiah Pendidikan Dasar Vol. 10 No. 02 (2025): Volume 10, Nomor 02 Juni 2025 publish
Publisher : Program Studi Pendidikan Guru Sekolah Dasar FKIP Universitas Pasundan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23969/jp.v10i02.27976

Abstract

This research aims to explore the process of internalizing mardhatillah values in shaping students' character at SD IT Alam Garut. Using a qualitative case study approach, data were collected through in-depth interviews, participant observation, and document analysis involving school principals, teachers, students, and parents. The findings reveal that the internalization process takes place through exemplary behavior by teachers, consistent religious routines, integration of values into the curriculum, and the establishment of a value-based school culture. Students exhibit positive character traits such as honesty, responsibility, discipline, and empathy, which are rooted in spiritual awareness. However, challenges arise in sustaining these values outside the school due to limited parental involvement and inconsistent reinforcement at home. The school leadership plays a crucial role in ensuring that the vision of mardhatillah remains the foundation of educational programs and institutional policies. Overall, the internalization of mardhatillah values at SD IT Alam Garut contributes effectively to the development of students’ character, although it requires stronger synergy between school and family to maintain consistency in students’ moral behavior across contexts. Keywords: mardhatillah values, character education, internalization;
THE EFFECTIVENESS OF BIOSYNTHESIZED ZnO NANOPARTICLES AS ANTIBACTERIALS: A LITERATURE REVIEW Nopriyanti, Selly; Mulyani, Yani
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 10 No 3 (2025)
Publisher : Universitas Muhammadiyah Ahmad Dahlan Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v10i3.1712

Abstract

One of the human infections caused by bacteria is digestive tract infection, some of these bacteria include S.typhi, E.coli, S.dysenteriae. Antibiotics are required to treat infectious diseases caused by microbes; however, most antibiotics cause resistance to these microbes. To avoid this, researchers are interested in developing plant-derived antibiotics. This review aims to evaluate the antibacterial effectiveness of ZnO nanoparticles synthesized from plant extracts or microorganisms and their antibacterial activity against gram-positive bacteria (B. Cereus & S. Aureus) and gram-negative bacteria (E. Coli, K. Pneumonia & S. Thypi).  From this review, it can be concluded that ZnO nanoparticles have significant antibacterial activity against gram-negative bacteria. This antibacterial effectiveness is influenced by the particle size, ZnO-NPs concentration, and environmental conditions, such as pH and temperature. However, further studies are needed to determine the effectiveness of biosynthesized ZnO nanoparticles and their activities other than antibacterials. Keywords: Zinc Oxide Nanoparticles, Nanoparticles, Antibacterial, Biosynthesis, Green Synthesi 
EFFECTIVENESS OF THE MERDEKA TEACHING PLATFORM (PMM) AS A MEDIA FOR TEACHER PROFESSIONAL DEVELOPMENT IN DRIVE SCHOOLS Mulyani, Yani; Maulana, Rizka Husnu; Badrudin, Badrudin
PROCEEDING OF INTERNATIONAL CONFERENCE ON EDUCATION, SOCIETY AND HUMANITY Vol 2, No 2 (2024): Third International Conference on Education, Society and Humanity
Publisher : PROCEEDING OF INTERNATIONAL CONFERENCE ON EDUCATION, SOCIETY AND HUMANITY

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This research aims to analyze the effectiveness of the Merdeka Mengajar Platform (PMM) as a medium for developing teacher professionalism in Sekolah Penggerak. The study was conducted in several Sekolah Penggerak in the Sindangwangi District of Majalengka Regency, involving teachers and school principals as the main participants. A qualitative approach with a case study method was used to explore in-depth data related to the experiences, perceptions, and impact of PMM usage on teacher professional competence. The research findings indicate that PMM significantly contributes to supporting the development of pedagogical and managerial competencies of teachers, especially through its integrated continuous development features. However, its effectiveness is influenced by factors such as technology access, user motivation, and school institutional support. This research recommends strengthening PMM usage training and improving supporting infrastructure to optimize the benefits of this platform in supporting the Sekolah Penggerak program
Ethyl Acetate Fraction of Gynura procumbens Mitigates Hyperglycemia, Dyslipidemia, and Tissue Damage in Streptozotocin-Induced Diabetic Rats Mulyani, Yani; Kaniawati, Marita; Aligita, Widhya; Nugraha, Eka Rahmat
Sciences of Pharmacy Volume 4 Issue 4
Publisher : ETFLIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0404371

Abstract

Dyslipidemia is a lipid metabolism disorder frequently associated with diabetes mellitus and known to increase cardiovascular risk. Although Gynura procumbens has been reported to possess antidiabetic and antidyslipidemic properties, studies focusing on the specific effects of its ethyl acetate fraction remain limited. This study investigated the therapeutic potential of the ethyl acetate fraction of ethanol extract from G. procumbens in streptozotocin-induced diabetic rats, particularly its impact on blood glucose, lipid profiles, and histological changes in pancreatic and aortic tissues. Thirty rats were randomly assigned to six groups: normal control, diabetic control, glibenclamide, simvastatin, and extract-treated groups at 100 and 150 mg/kg body weight. After 28 days of treatment, the 150 mg/kg dose significantly reduced blood glucose by 61.3%, total cholesterol by 42.1%, triglycerides by 47.3%, and LDL by 55.0%, while increasing HDL by 6.3% compared to diabetic control (p < 0.05). Histological analysis demonstrated regeneration of pancreatic β-cells and improvement of vascular structure in the aorta. These findings suggest that the ethyl acetate fraction of G. procumbens may serve as a promising natural agent for managing diabetes and dyslipidemia.
ZUHUD DAN GAYA HIDUP BERKELANJUTAN MENURUT TINJAUAN SUFISTIK DAN PSIKOLOGI ISLAM Mulyani, Yani; Rahayu, Solihah Sari; Jamaludin, Jamaludin
Jurnal Pendidikan Indonesia : Teori, Penelitian, dan Inovasi Vol 5, No 5 (2025): Jurnal Pendidikan Indonesia : Teori, Penelitian, dan Inovasi
Publisher : Penerbit Widina, Widina Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59818/jpi.v5i5.1956

Abstract

Zuhud is not merely understood as physical detachment from worldly possessions but rather as an inner release from excessive dependence on material pleasures. In the context of modern life, which is dominated by materialism and consumerism, zuhud provides an alternative conscious lifestyle that balances worldly needs with ultimate spiritual goals. This article aims to examine the concept of zuhud within classical Sufi traditions and to explore its relevance to sustainable living in contemporary society. The study employs a library research method with Sufi and Islamic psychological (nafsiyological) approaches. The findings reveal that zuhud encompasses significant spiritual, psychological, and social dimensions. Spiritually, zuhud fosters transcendental awareness; psychologically, it contributes to self-control and mental well-being; and socially, it promotes simplicity, solidarity, and sustainability in resource utilization. Thus, zuhud can be recontextualized as an ethical and spiritual framework to address the value crisis, psychological pressures, and ecological challenges of modern society.ABSTRAKZuhud tidak sekadar dimaknai sebagai sikap menjauhi dunia secara fisik, tetapi lebih pada pelepasan ketergantungan batin terhadap kenikmatan materi yang berlebihan. Dalam konteks kehidupan modern yang sarat dengan materialisme dan konsumerisme, nilai-nilai zuhud menghadirkan alternatif gaya hidup berkesadaran yang mampu menyeimbangkan kebutuhan duniawi dan ukhrawi. Artikel ini bertujuan untuk mengkaji konsep zuhud dalam tradisi tasawuf klasik serta mengeksplorasi relevansinya terhadap gaya hidup berkelanjutan di era kontemporer. Penelitian menggunakan metode studi pustaka dengan pendekatan sufistik dan psikologi Islam (nafsiyologis). Hasil kajian menunjukkan bahwa zuhud memiliki dimensi spiritual, psikologis, dan sosial yang signifikan. Pada dimensi spiritual, zuhud menumbuhkan kesadaran transendental; pada dimensi psikologis, ia berkontribusi dalam pengendalian nafsu serta kesehatan mental; dan pada dimensi sosial, ia mendorong pola hidup sederhana, solidaritas, serta keberlanjutan dalam pemanfaatan sumber daya. Dengan demikian, zuhud dapat direkontekstualisasikan sebagai kerangka etis dan spiritual untuk menghadapi krisis nilai, tekanan psikologis, dan tantangan ekologis masyarakat modern.
Co-Authors Adang Hambali, Adang Agus Sulaeman Aligita, Widhya Amini, Nadia Ushfuri Ani Anggriani, Ani Assalam, Sunan Hanif Ihsan Bachrudin, Panji Bagus Suryadi, Bambang Bambang Kelana Simpony Choirunnisa, Zulfy Davronov, Istamkhuja Olimovich dirgahayu, inggrid Elin Yulinah Embas Saraswati, Dewa Ayu Eti Rahmawati Fajeri, Nur Iman Garnadi Jafar, Garnadi Hadiantini, Dian Hasan Basri Hasimun, Patonah Hidayat, Abdilah Alam Hernan I Gusti Agung Ayu Hari Triandini I Ketut Adnyana Ika Kurnia Sukmawati Ilham Suparman, Muhamad Iskandar Jioe, Yulius Isvahanie, Salsha Rifa Jajang Jafar Sodik Jamaludin . Khotimah, Nur Intan Husnul Kurnia Sukmawati, Ika Kurniasih, Imas Marita Kaniawati Maulana, Rizka Husnu Melysa, Melysa Muhtadin Mukhlishah Muyassar M, Raihan Mu’atawakil, Raihan Muyassar Nopriyanti, Selly Nugraha, Budy Nugraha, Eka Rahmat Nurswardiana, Hanna Pasha, ED. Yunisa Mega Patonah, Patonah Pratiwi, Lili Dinda Prawestyi, Poety Putriyanti, Al-fira Rahayu, Sri Mulyati Rofi Fahmi, Dede Salam, Mochamad Fadlani Sapitri, Wina Sari, Mela Mustika Sholiehah, Nurul Siti Balqis, Salwa Siti Saidah Solihah Sari Rahayu Solihah, Nurlaella Sriwantika, Ika Sumarna, Rendi Supala Sutrisno, Entris Tambunan, Irisanna Utami, Pujani Vitniawati, Vina