Article Per Year (5 Year)
p-Index From 2021 - 2026
4.197
P-Index
This Author published in this journals
All Journal Indonesian Journal of Tropical and Infectious Disease The Indonesian Biomedical Journal Paediatrica Indonesiana Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Jurnal Kreativitas PKM Jurnal Respirasi (JR) Biomolecular and Health Science Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Majalah Biomorfologi (Biomorphology Journal) Jurnal Layanan Masyarakat (Journal of Public Service) Cardiovascular and Cardiometabolic Journal (CCJ) Indian Journal of Forensic Medicine & Toxicology Neurona Folia Medica Indonesiana
Yetti Hernaningsih
Clinical Pathology Department, Dr. Soetomo Hospital Surabaya
Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Earth & Planetary Sciences Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 49 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : The Indonesian Biomedical Journal

 1 
Lactiplantibacillus plantarum IS-10506 Enhances Tight Junction Integrity in Bronchial Epithelium: An Experimental Study Fetarayani, Deasy; Soegiarto, Gatot; Surono, Ingrid Suryanti; Endaryanto, Anang; Athiyyah, Alpha Fardah; Hernaningsih, Yetti; Fauziah, Dyah; Sudiana, I Ketut; Utomo, Budi; Prakoeswa, Cita Rosita Sigit
The Indonesian Biomedical Journal Vol 16, No 2 (2024)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v16i2.2995

Abstract

BACKGROUND: Airway epithelium constitutes the initial structural defense against inhaled allergens, with its integrity primarily maintained through the formation of tight junctions (TJ) consisting of claudins, occludins, and zonula occludens (ZO). Currently, the effects of probiotics on airway TJ remain unclear. Therefore, this study was conducted to explore the impact of Lactiplantibacillus plantarum IS-10506, a native probiotic from Indonesia, on bronchial epithelial TJ in a mouse model of allergic airway inflammation.METHODS: Twenty-four BALB/c mice were randomly assigned to three groups: negative control, positive control subjected to Dermatophagoides pteryonissinus (Der p) sensitization and challenge, and treatment group exposed to Der p and administered L. plantarum IS-10506 since one week before sensitization up to three weeks after. The expression levels of claudin-18, occludin, and ZO-1 were investigated through immunohistochemistry analysis and quantified based on the immunoreactive score (IRS). RESULTS: The results of this study demonstrated that L. plantarum IS-10506 significantly enhanced the expressions of claudin-18, occludin, and ZO-1 (p<0.05).CONCLUSION: These findings underscore the probiotic's role in fortifying the integrity of airway TJ.KEYWORDS: allergic inflammation, probiotic Lactiplantibacillus plantarum, immunology, respiratory system, tight junction, occludin, claudin, zonula occludens
Co-Authors -, Regina Rania Cahya Kusumaningrum Adil Dinata Simangunsong Agil Saputra Alfino Validita Sidiq Ali Hasan, Zulfikar Alifadiningrat, Dianira Hanum Febia Almira, Naufalia Ghina Alpha Fardah Athiyyah Amalia, Yustisia Anang Endaryanto Andi Cahyadi Andrianto Andy Cahyadi Aprianto, Koko Ardhi, Mohammad Saiful Arifa Mustika Arifa Mustika Arifoel Hajat Armayani, Erawati Aryati Aryati Aulia, Fauqa Arinil Awalia Awaliah Baiq Nasha Islaeli Bintoro, Siprianus Ugroseno Yudho Budi Utomo Chelssi Gloria Tessari Cita Rosita Sigit Prakoeswa Citra Amaniah Anhar Danny Meganingdyah Primartati Deasy Fetarayani Desty Indah Sari Dwiyanti Puspitasari, Dwiyanti DYAH FAUZIAH, DYAH Elvan Dwi Widyadi Elvan Dwi Widyadi Endang Retnowati Endang Retnowati Endang Retnowati Erawati Armayani Esti Rohani Farida Nur’Aini Fauqa Arinil Aulia Fita Triastuti Gatot Soegiarto Hanik Badriyah Hidayati,* Mohammad Hasan Machfoed,* Kuntoro,** Soetojo,*** Budi Santoso,**** Suroto,***** Budi Utomo****** Hans Kristian Nugraha, Hans Kristian Hartono Kahar, Hartono Hasan, Helmia Heny Arwati I Dewa Gede Ugrasena Indrasari, Yulia Indriastuti, Endah INGRID SURYANTI SURONO Ire Puspa Wardhani Jusak Nugraha Juwita, Syntia Tanu Kezia Warokka Putri Koko Aprianto Kusuma, Edward Putra Kusumaningrum, Regina Rania Cahya Lazuwardi, Rasya Azka Lefi, Achmad Meiti Muljanti, Meiti Mia Ratwita A Mia Ratwita Andarsini Mochammad Reza Desianto MOCHAMMAD THAHA Muhlisa, Nurul Musholli Himmatun Nabilah Nadya Rinda Eka Rana Narazah Mohd Yusoff Nastasya Nunki Nathalya Dwi Kartikasari Ni Made Rindra Hermawathi Notopuro, Paulus Budiono Novi Ersanto Nugraha, Hans K Nunki, Nastasya Nur‘ Aini, Farida Prasetiyanti, Rinta Puspa Wardhani Puspa Wardhani, Soebagijo Adi Puspitasari, Yessy Putri Rahayu Rahmi Rusanti Rahmi Rusanti, Rahmi RINI RINI Rinta Prasetiyanti Romadhon, Pradana Zaky Rusli, Musofa Ryzky Widi Atmaja Ryzky Widi Atmaja S.Pd. M Kes I Ketut Sudiana . Sellynastiti, Sarah Triwinar Shinta Lungit Ambaringrum Sidarti Soehita Siti Khaerunnisa Soeprapto Ma’at Sri Ratna Dwiningsih Suprapto Ma&#039;at Ma&#039;at Suprapto Ma’at Syntia TJ Tanzilia, May Fanny Teguh Satrio Thengkano, Irwanto Ugroseno Ugroseno Uli Mas'uliyah Indarwati Ummi Maimunah Veithzal Rivai Zainal Wardhani, Puspa Widaninggar Rahma Putri Widodo Widodo Widodo Widodo Widodo Widodo Widodo Widodo Wulyansari Wulyansari Yanuari Primariawan, Relly Yosua Butar Butar Yulia Nadar Indrasari Yusuf, Moch Zaky Firmawan El-Hakim