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All Journal SAINSMAT bionature UNM Journal of Biological Education Biology Teaching and Learning Jurnal IPA Terpadu Jurnal Biologi Tropis Jurnal Biogenerasi Jurnal Ilmiah Biologi UMA (JIBIOMA) BioEksakta : Jurnal Ilmiah Biologi Unsoed PENGABDI: Jurnal Hasil Pengabdian Masyarakat Jurnal Pengabdian Kepada Masyarakat Patikala SAINSMAT: Jurnal Ilmiah Ilmu Pengetahuan Alam BIO-CONS: Jurnal Biologi dan Konservasi Journal of Science and Education Research Paramacitra : Jurnal Pengabdian Masyarakat Jurnal Abdi Negeriku SMART: Jurnal Pengabdian Kepada Masyarakat JKM: Jurnal Kemitraan Masyarakat Bionature
Halifah Pagarra
State University Of Makassar
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Veterinary Other

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Perbedaan Ekstrak Etanol dan Etil Asetat Daun Lada (Piper nigrum L) terhadap Aktivitas Antimikroba Hartati, H.; Pagarra, Halifah
Sainsmat : Jurnal Ilmiah Ilmu Pengetahuan Alam Vol 7, No 1 (2018): Maret
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (701.292 KB) | DOI: 10.35580/sainsmat7164702018

Abstract

Penelitian ini bertujuan untuk mengetahui perbedaan ekstrak etanol dan ekstrak etil asetat daun lada (Piper nigrum L) terhadap aktivitas antimikroba Staphylococcua aureus, Escherichia coli dan Candida albicans. Metode maserasi telah digunakan untuk mengekstrak daun lada dengan menggunakan dua pelarut yaitu etanol 70% dan etil asetat. Hasil ekstrak selanjutnya dilakukan uji aktivitas antimikroba. Hasil ekstrak etanol daun lada diperoleh rendemen yang lebih tinggi yaitu 24,64% dibandingkan dengan ekstrak etil asetat 9,18%. Ekstrak etanol daun lada memiliki aktivitas antimikroba lebih tinggi dibandingkan ekstrak etil asetat daun lada terhadap bakteri Staphylococcua aureus,dan Escherichia coli tetapi tidak menghambat jamur Candida albicans  pada konsentrasi 10%.
Effect Of Blended Learning On Independence And Learning Outcomes Of Grade Xi Learners Khatimah, Khusnul; Adnan, Adnan; Pagarra, Halifah
Sainsmat : Jurnal Ilmiah Ilmu Pengetahuan Alam Vol 13, No 2 (2024): September
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35580/sainsmat132647482024

Abstract

Research was carried out with the aim of finding out blended learning on the independence and learning outcomes of class XI MAN 1 Makassar City students. A posttest only control design was used in this research, which is a type of quasiexperimental research. Entire class of XI MAN 1 Makassar City, consisting of 12 classes, was used as the population, then selected by random sampling to obtain 4 classes as samples consisting of 3 experimental classes and 1 control class. Implementation of learning in experimental group used an ICT-based MPBK model with blended learning approach, while in the control group used direct instruction learning model with teacher-based learning approach. Data collection on learning independence is non-test instrument in the form of questionnaire and data collection on learning outcomes is test instrument in form of objective and subjective questions. Data results were then analyzed using descriptive statistics followed inferential statistics. Results of the descriptive analysis showed that the experimental group had better independence and learning outcomes than tcontrol group. Results of the inferential analysis used normality tests, homogeneity, hypothesis testing with multivariate analysis of variance tests and further Tukey HSD tests. From hypothesis testing it was found that the significance value was 0.000 < 0.05, so there was influence of blended learning on independence and learning outcomes of class XI MAN 1 Makassar City students. Results of further tests with Tukey HSD for independence and learning outcomes showed that experimental and control groups were in different subset columns so that there were significant differences between groups, which means that statistically blended learning has influence on students' independence and learning outcomes.
Pengembangan Nanoemulsi Ekstrak Daun Kelor (Moringa Oleifera) Sebagai Antioksidan, Antibakteri Dan Antiluka Hidayat, Muh Akbar; Hartati, Hartati; Pagarra, Halifah; Sahribulan, Sahribulan
Sainsmat : Jurnal Ilmiah Ilmu Pengetahuan Alam Vol 14, No 1 (2025): Maret
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35580/sainsmat141671352025

Abstract

This study aims to determine the effect of moringa leaf extract nanoemulsion (Moringa Oleifera Lamk.) on bacterial growth, antioxidant activity and wound healing potential in white rats (Rattus novegicus). The research method includes extraction of Moringa, making nanoemulsion of Moringa leaf extract concentrations of 75, 100 and 125 milligrams. Droplet nanoemulsion using Particle Size Analyzer (PSA), antibacterial with inhibition zone diameter (mm), antioxidant with DPPH (1,1 diphenyl-2-picrylhydrazyl) and measurement of wound healing activity by determining the percentage of wound closure in rats. The study used a completely randomized design (CRD) and Analysis of Variant (ANOVA) test followed by Tukey test. Antioxidant activity obtained IC50 Formula 1 amounted to 157.35 ppm, Formula 2 amounted to 123.40 ppm, Formula 3 amounted to 110.12 ppm, Moringa leaves extract amounted to 58.63 ppm and BHA comparison amounted to 6.84 ppm. Moringa leaf extract and nanoemulsion formula showed good wound healing activity which was faster than the positive control. It is found that moringa leaf extract and nanoemulsion formulation have antibacterial activity against S. aureus and E. coli. The wound healing activity of the nanoemulsion formulation was classified as good in mice with a faster wound healing process than the positive control.
The Effect of Matoa (Pometia pinnata) Leaves Ethanol Extract On Reducing Cholestrol Levels In Male Mice (Mus musculus) Haq, Muhammad Naufal Syaiful; Pagarra, Halifah; Muis, Abd.; Salsabila, Shopia
Sainsmat : Jurnal Ilmiah Ilmu Pengetahuan Alam Vol 14, No 1 (2025): Maret
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35580/sainsmat141720372025

Abstract

This research aims to determine the total phenolic content and antioxidant activity of the ethanol extract of matoa (Pometia pinnata) leaves and their effect on the cholesterol levels of male mice (Mus musculus). To determine the total phenolic content using the Folin-Ciocalteu method and the DPPH method to measure antioxidant activity. The effect of matoa leaf extract on reducing cholesterol levels in mice used a completely randomized design (CRD) with 15 mice divided into 5 treatment groups with 3 replications, namely P1 (Extract 175 mg/kgBW), P2 (Extract 350 mg/kgBW), P3 (Extract 700 mg/kgBW), K+ (Simvastatin 0.10 mg/kgBW), and K- (Na-CMC 1%). Extraction uses the maceration method with 70% ethanol solvent. The total phenolic test results were 26.24872 mgGAE/g. The results of measuring antioxidant activity obtained an IC50 of 1,961 ppm. The results of testing cholesterol levels showed that there was an effect of giving ethanol extract of Matoa (Pometia pinnata) leaves on reducing cholesterol levels in male mice (Mus musculus). Giving ethanol extract of Matoa leaves at a dose of 350 mg/kgBW is effective in reducing cholesterol levels. So it can be concluded that the ethanol extract of Matoa leaves has an effect on reducing cholesterol levels in male mice.
Antibacterial Activity of Pegagan (Centella asiatica) Leaf Extract and Fractions Against Escherichia coli and Staphylococcus aureus Pagarra, Halifah; Saalino, Erlin; Hartati, Hartati
Sainsmat : Jurnal Ilmiah Ilmu Pengetahuan Alam Vol 13, No 2 (2024): September
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35580/sainsmat132643332024

Abstract

Pegagan atau yang dikenal dengan nama Pegagan merupakan tanaman perdu yang mengandung zat gizi dan senyawa aktif yang baik bagi tubuh, karena memiliki khasiat sebagai antibakteri, antivirus, antihipertensi, diuretik dan antiinflamasi. Tanaman ini merupakan sumber senyawa fenolik, flavonoid, triterpenoid, alkaloid dan tanin. Penelitian ini bertujuan untuk mengevaluasi aktivitas antibakteri daun pegagan. Daun pegagan diekstraksi dengan pelarut etanol 70%, kemudian difraksinasi dengan pelarut n-heksana, etil asetat dan metanol. Evaluasi aktivitas antibakteri menggunakan metode difusi cakram pada konsentrasi 5%, 10% dan 15% terhadap Escherichia coli dan Staphylococcus aureus dengan mengukur zona bening yang terbentuk di sekitar kertas cakram. Hasil penelitian menunjukkan bahwa ekstrak etanol 70%, fraksi etil asetat dan fraksi metanol:air memiliki aktivitas antibakteri terhadap kedua bakteri tersebut, sedangkan fraksi n-heksana tidak memiliki aktivitas antibakteri terhadap kedua bakteri tersebut. Ekstrak etanol dengan konsentrasi 5% menunjukkan aktivitas paling efektif dalam menghambat Escherichia coli dengan zona hambat 13,67 ± 0,428 mm dan fraksi metanol:air dengan konsentrasi 5% terhadap Staphylococcus aureus dengan zona hambat 9,35 ± 0,17 mm.Kata kunci: Antibakteri, Centella asiatica, Escherichia coli, Staphylococcus aureus
Co-Authors A. Irma Suryani A. Mushawwir Taiyeb, A. Mushawwir Abd Muis Abd.Muis Achya, Feny Fadillah Adnan Adnan Adnan Adnan Alimuddin Ali Andi Asmawati Azis Andi Faridah Arsal Andi Muflihunna Asham Bin Jamaluddin Asriani Asriani, Asriani Azis, A. Asmawati Dwi Putri Ulan Sari Patongai, Dian Firdaus Daud Haeruddin, Muhammad Ilham Wardana Handayani , Resti Haq, Muhammad Naufal Syaiful HARTATI Hartati Hartati Hartati, H. Hartono Haryani Haryani Hidayat, Muh Akbar Hilda Karim Hiola, Siti Fatmah Hiola, St.Fatmah Idris, Irma Suryani Irzal, Ummul Aulia Ismail . Junda , Muhammad Kamaruddin, Fatmah Khatimah, Khusnul Maisarah, Indah Mu'nisa, A. Mu'nisa, Andi Muhammad Naufal Syaiful Haq Mus, Nurzakiyyah Musawira Mushawwir Taiyeb Nara, Intan Permata Naufal Syaiful Haq, Muhammad Nurhayati B Nurul Aisyah Syachrul, Wulandari Rachmawaty Rachmawaty Rachmawaty, Rachmawaty Randa M, Asty Resti Handayani, Resti Rimba, Lovely Grace Saalino, Erlin Sahribulan, Sahribulan Saleh, Andi Rahmat Salsabila, Shopia Sorry, Elsa Rosyana St. Fatmah Hiola Sumiati Side Syamsiah, Syamsiah Syamsu, Andi Mu'nisa Syawaluddin, Ahmad Taiyeb , Mushawwir Tulutfiah, Besse Afidah Utami, Putri Nurul Wana, Nur Wardhana, Muhammad Ilham Yusminah Hala Yusuf, Yusnaeni