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All Journal Smart Medical Journal Jurnal Respirologi Indonesia Majalah Kedokteran Andalas Jurnal Respirasi (JR) Health and Medical Journal Indian Journal of Forensic Medicine & Toxicology Respiratory Science Cermin Dunia Kedokteran
Putra, Andika Chandra
Departemen Pulmonologi Dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Indonesia-RSUP Persahabatan, Jakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Journal : Jurnal Respirologi Indonesia

 1 
Covid-19 Patient Condition at Early Pandemic in Jakarta Andika Chandra Putra; Wiwien Heru Wiyono; Mohammad Fahmi Alatas; Aulya Fairuz; Fransiska Fransiska; Bettia Bermawi; Ratna Moniqa; Hendra Koncoro; Laurentius Aswin Pramono; Maria Edith Sulistio; Ramzi Ramzi; Robert Sinto; Rachmat Hamonangan; C. Krismini Dwi Irianti; JB Endrotomo Sumargono
Jurnal Respirologi Indonesia Vol 41, No 3 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i3.193

Abstract

Background: COVID-19 is a disease caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) that has become a pandemic. It became apparent that COVID-19 transmitting from person to person. The clinical manifestations and characteristics of COVID-19 encompassing from asymptomatic infection until severe pneumonia and death. This study aimed to describe and compare the characteristics between COVID-19 suspected patients and confirmed patients at an early pandemic in Jakarta, Indonesia. Methods: A cross-sectional design was used in this study. Data were collected from March to April 2020 using the electronic health record reporting database, initial laboratory tests, and RT-PCR for SARS-CoV-2 results. There were 58 subjects: 43 COVID-19 confirmed patients and 15 COVID-19 suspected patients. Results: Male was found predominantly in COVID-19 confirmed patients than female. The mean age of confirmed patients was 49,6 years old. Nearly half of the confirmed patients had comorbidities namely hypertension and diabetes mellitus. Fever and cough were the most common presenting symptoms, and they were also found in suspected patients. Confirmed patients tended to have lymphopenia and neutrophilia. Pulmonary infiltrate was the most common feature in both confirmed and suspected patients. Conclusion: There were no significant differences found between COVID-19 confirmed and suspected cases regarding demographic characteristics, comorbidities, presenting symptoms, physical examination results, laboratory tests, and chest x-ray results. COVID-19 confirmed patients had a history of exposure to COVID-19 confirmed patients.
Inflammatory Markers upon Admission as Predictors of Outcome in COVID-19 Patients Budhi Antariksa; Erlina Burhan; Agus Dwi Susanto; Mohamad Fahmi Alatas; Feni Fitriani Taufik; Dewi Yennita Sari; Dicky Soehardiman; Andika Chandra Putra; Erlang Samoedro; Ibrahim Nur Insan Putra Darmawan; Hera Afidjati; Muhammad Alkaff; Rita Rogayah
Jurnal Respirologi Indonesia Vol 41, No 4 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i4.185

Abstract

Background: Coronavirus disease 2019 (COVID-19) may cause dysregulation of the immune system, leading to hyperinflammation. Inflammatory markers can be used to predict in-hospital mortality in COVID-19 patients. This research was aimed to investigate the association between the levels of various inflammatory markers and mortality in COVID-19 patients.Methods: This study was conducted at Persahabatan National Respiratory Referral Hospital, Indonesia. Blood tests were performed upon admission, measuring the C-reactive protein, PCT, leukocyte, differential counts, and platelet count. The outcome measured was the mortality of hospitalized COVID-19 patients. Statistical analysis methods included the Mann–Whitney U test, receiver operating characteristic (ROC) analysis, and area under the curve (AUC) test.Results: Total 110 patients were included, and the laboratory values were analyzed to compare survivors and non-survivors. The non-survivor group had significantly higher leukocyte count, lower lymphocyte count, higher CRP and PCT levels, higher neutrophil-to-lymphocyte ratio (NLR), higher platelet-to-lymphocyte ratio (PLR), and lower lymphocyte-to-CRP ratio. As predictors of mortality, AUC analysis revealed that PCT, CRP, NLR, and PLR had AUCs of 0.867, 0.82, 0.791, and 0.746, respectively.Conclusions: Routine and affordable inflammatory markers tested on admission may be useful as predictors of in-hospital mortality in COVID-19 patients requiring hospitalization.
Indonesian Society of Respirology Position Paper on Lung Cancer Control in Indonesia Andarini, Sita; Santoso, Andintia Aisyah; Arfiansyah, Mochammad Aris; Syahruddin, Elisna; Zaini, Jamal; Putra, Andika Chandra; Kurniawan, Ferry Dwi; Ermayanti, Sabrina; Soeroso, Noni Novisari; Munir, Sri Melati; Infianto, Andreas; Setijadi, Ana Rima; Setyawan, Ungky Agus; Wulandari, Laksmi; Haryati, Haryati; Jasminarti, Ida Ayu; Hidayat, Moulid; Santoso, Arif
Jurnal Respirologi Indonesia Vol 44, No 4 (2024)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v44i4.884

Abstract

Lung cancer is a major health concern in Indonesia due to its increasing prevalence, late-stage diagnosis, younger population, and high mortality. Addressing this issue requires nationwide implementation of comprehensive lung cancer control, which includes risk reduction and prevention strategies, focusing on tobacco control and air pollution mitigation. Screening with low-dose computed tomography (LDCT) and early detection in symptomatic patients, along with TB screening programs and all non-communicable diseases, is strongly recommended to enhance early case findings, treatment effectiveness, and overall patient outcomes. A multidisciplinary team (MDT) approach is important to ensure accurate diagnosis and comprehensive care. Moreover, the integration of palliative care at the early stages of advanced lung cancer is vital, focusing on symptom management and enhancing the quality of life for patients. While national guidelines are available for the diagnosis and treatment of lung cancer, significant disparities in healthcare access remain across Indonesia. Thus, it is essential to improve universal health coverage and referral systems to guarantee equal access to lung cancer care for patients at all levels through advocacy and ease of access.
Pulmonary Hypertension: Understanding the Underlying Anatomy and Physiology of Pulmonary Circulation Amien, Bagus Radityo; Putra, Andika Chandra
Jurnal Respirologi Indonesia Vol 45 No 2 (2025)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v45i2.779

Abstract

The circulatory system has a vital role in fulfilling oxygen demand in tissues and maintaining homeostasis. There are two types of circulatory systems in our body, the systemic and pulmonary circulation. Pulmonary circulation, the critical pathway of blood oxygenation through heart-lung-pulmonary vascular interaction, remains poorly understood despite its central role in the various pulmonary vascular diseases. One of the most prevalent pulmonary vascular diseases is pulmonary hypertension (PH), which is characterized by high mortality and disease progression. A thorough understanding of the physiologic structure and function of pulmonary circulation is essential for diagnosing and treating patients with PH.  Pulmonary blood flow is determined by pulmonary vascular pressure (PVP) and pulmonary vascular resistance (PVR). Lung volume, neural factors (sympathetic and parasympathetic nervous systems), humoral factors (vasoconstrictor and vasodilator), and alveolar hypoxia play an important role in regulating PVR. Alveolar hypoxia triggers hypoxic pulmonary vasoconstriction to maintain the ventilation-perfusion ratio balance. High PVR increases pulmonary arterial pressure (Pa), which is the main pathophysiology of PH. In addition, endothelial dysfunction and vasoactive imbalance also contribute significantly to the pathogenesis of the disease.
Indonesian Society of Respirology Position Paper on Lung Cancer Control in Indonesia Andarini, Sita; Santoso, Andintia Aisyah; Arfiansyah, Mochammad Aris; Syahruddin, Elisna; Zaini, Jamal; Putra, Andika Chandra; Kurniawan, Ferry Dwi; Ermayanti, Sabrina; Soeroso, Noni Novisari; Munir, Sri Melati; Infianto, Andreas; Setijadi, Ana Rima; Setyawan, Ungky Agus; Wulandari, Laksmi; Haryati, Haryati; Jasminarti, Ida Ayu; Hidayat, Moulid; Santoso, Arif
Jurnal Respirologi Indonesia Vol 44 No 4 (2024)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v44i4.884

Abstract

Lung cancer is a major health concern in Indonesia due to its increasing prevalence, late-stage diagnosis, younger population, and high mortality. Addressing this issue requires nationwide implementation of comprehensive lung cancer control, which includes risk reduction and prevention strategies, focusing on tobacco control and air pollution mitigation. Screening with low-dose computed tomography (LDCT) and early detection in symptomatic patients, along with TB screening programs and all non-communicable diseases, is strongly recommended to enhance early case findings, treatment effectiveness, and overall patient outcomes. A multidisciplinary team (MDT) approach is important to ensure accurate diagnosis and comprehensive care. Moreover, the integration of palliative care at the early stages of advanced lung cancer is vital, focusing on symptom management and enhancing the quality of life for patients. While national guidelines are available for the diagnosis and treatment of lung cancer, significant disparities in healthcare access remain across Indonesia. Thus, it is essential to improve universal health coverage and referral systems to guarantee equal access to lung cancer care for patients at all levels through advocacy and ease of access.
Co-Authors Agus Dwi Susanto Agustiyanti, Dian Fitria Ahmad Hudoyo Amien, Bagus Radityo Ana Rima Setijadi Andarini, Sita Anky Zannati Anwar Jusuf Arfiansyah, Mochammad Aris Arif Santoso Aufa, Akhdan Aulya Fairuz Azika, Wira Norman Bahri, Syukrini Bettia Bermawi Budhi Antariksa Budi Haryanto C. Krismini Dwi Irianti Dewi Yennita Sari Elisna Syahruddin Elsye Souvriyanti, Elsye Erdayani, Eva Erlina Burhan Erlina, Andi Ermayanti, Sabrina Fariz, Nurwidya Fasli Jalal Fransiska Fransiska Ginindha Izzati Sabila Gusnanto, Arief Haryati Haryati Hendra Koncoro Hera Afidjati Herjuno Ari Nugroho, Herjuno Ari Hidayat, Moulid Ibrahim Nur Insan Putra Darmawan Idris Idris Ifan Aulia Candra Indra Kusuma Indriawati, Indriawati Infianto, Andreas Isbaniah, Fathiyah Jamsari Jamsari Jasminarti, Ida Ayu JB Endrotomo Sumargono Kurniawan, Ferry Dwi Laksmi Wulandari Laurentius Aswin Pramono Maria Edith Sulistio Mohamad Fahmi Alatas Mohammad Fahmi Alatas Muammar Emir Ananta Muchtiar, Mulyadi Muhamad Rizqy Fadhillah Muhammad Alkaff Noni Novisari Soeroso Pangestu, Hendri Popi Hadi Wisnuwardhani, Popi Hadi Rachmat Hamonangan Ramzi Ramzi RATIH ASMANA NINGRUM Ratna Moniqa Retno Ariza Soeprihatini Soemarwoto Ridwanuloh, Asep Muhammad Rifqatussaadah, Rifqatussaadah Rika Bur Rika Yuliwulandari, Rika Rita Rogayah Robert Sinto Samoedro, Erlang Saniyyah, Zahrah Santoso, Andintia Aisyah Setiawan, Ruby Setyawan, Ryan Haryo Setyawan, Ungky Agus Soehardiman, Dicky Sri Melati Munir Steven Jonathan Sushadi, Pangda Sopha Syazili Mustofa Taufik, Feni Fitriani Tjandra Yoga Aditama Utomo, Ahmad Rusdan H Utomo, Ahmad Rusdan Handoyo wahyuni wahyuni Wawan Abdullah Setiawan Wira Winardi Wiwien Heru Wiyono Wulandari, Ari Sulistyo Yanwirasti Yulia Suciati Zaini, Jamal