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All Journal HAYATI Journal of Biosciences Jurnal Gizi dan Pangan ACTA VETERINARIA INDONESIANA Jurnal Sain Veteriner Majalah Kedokteran Bandung Indonesian Journal of Biotechnology Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Veterinary Sciences) ARSHI Veterinary Letters Jurnal Ilmu dan Teknologi Kayu Tropis Jurnal Kedokteran Hewan Jurnal Veteriner dan Biomedis Current Biomedicine Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Subangkit, Mawar
Sekolah Kedokteran Hewan Dan Biomedis, Institut Pertanian Bogor
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Earth & Planetary Sciences Economics, Econometrics & Finance Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Veterinary

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Journal : Current Biomedicine

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Activity of arabica green coffee bean (Coffea arabica) extract as an immunomodulator in mice (Mus musculus) infected with Staphylococcus aureus Aurellia, Sharon; Subangkit, Mawar; Andriyanto, Andriyanto
Current Biomedicine Vol. 2 No. 1 (2024): January
Publisher : School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/currbiomed.2.1.29-35

Abstract

Arabica green coffee bean is the most widely produced coffee bean in Indonesia. Studies have shown that arabica green coffee beans are rich in polyphenols and antioxidants, stimulating immune cell proliferation. This study investigated the immunomodulatory activity of arabica green coffee beans (Coffea arabica). Thirty mice (Mus musculus) with an average body weight of 30 g were divided into five groups: negative control, positive control, and groups administered arabica green coffee bean powder extract at doses of 0.03, 0.06, and 0.18 mg/30 g BW. It was orally administered once daily for 14 days. On the 15th day, the mice were intraperitoneally injected with non-pathogenic Staphylococcus aureus. After an hour, mice were necropsied for peritoneal fluid collection. Peritoneal fluid was stained with a peripheral blood smear, and the number of macrophages and lymphocytes was observed under a microscope. Data were analyzed using one-way analysis of variance (ANOVA), followed by Tukey’s test. The group administered with 0.18 mg/30 g body weight (BW) dose showed the highest average of macrophage and lymphocytes compared to the negative control group and any other groups. Arabica green coffee bean powder extract was shown to have immunomodulatory activity, with the highest activity observed at a dosage of 0.18 mg/30 g BW.
Hipertrofi sel goblet usus halus ayam kampung asal pasar tradisional Jakarta yang terinfeksi cacing cestoda Jerica, Monica Silva; Tiuria, Risa; Mayasari, Ni Luh Putu Ika; Nugraha, Arifin Budiman; Subangkit, Mawar
Current Biomedicine Vol. 2 No. 2 (2024): July
Publisher : School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/currbiomed.2.2.93-100

Abstract

Latar Belakang: Ayam kampung merupakan salah satu kebutuhan protein hewani yang sering dicari masyarakat. Pemeliharaan ayam kampung dengan sistem dibiarkan lepas menjadi predisposisi terinfeksi oleh parasit gastrointestinal. Tujuan: Penelitian ini bertujuan mengkaji perubahan sel epitel dan hipertrofi sel goblet pada saluran pencernaan ayam kampung yang terinfeksi cacing cestoda Raillietina spp. secara alami. Metode: Penelitian ini menggunakan tujuh preparat arsip histopatologi usus halus ayam kampung yang terinfeksi cacing cestoda. Sampel usus halus ayam kampung diambil dari dua pasar yang berbeda, yaitu pasar Pluit di Jakarta Utara dan pasar Kebayoran Lama di Jakarta Selatan. Hasil: Hasil pengamatan histopatologis pada preparat usus ditemukan deskuamasi epitel vili dan proliferasi sel-sel kripta yang diakibatkan oleh infeksi cacing cestoda. Sel goblet yang mengalami hipertrofi paling banyak ditemukan pada sampel preparat yang diambil dari pasar Kebayoran Lama, Jakarta Selatan (p>0,05). Simpulan: Dapat disimpulkan bahwa deskuamasi vili dan jumlah hipertrofi sel goblet terjadi akibat infeksi cacing cestoda pada mukosa usus halus ayam kampung.
Co-Authors Aditya Primawidyawan Ahmad Faried Alfarisi, Hamzah Alya Mardhotillah Azizah Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Anita Esfandiari Arief Boediono Aulia Andi Mustika Aulia Andri Mustika Aurelia, Sharon Aurellia, Sharon Az Zahra, Shafiyyah Bambang Pontjo Priosoeryanto Berry Juliandi Boenjamin Setiawan Christina Clarice Leksono D R Agungpriyono Deded Sarip Nawawi Deni Noviana Dertina Marni Purba Dewi R Agungpriyono Dian Anggraini Diana Krisanti Jasaputra Dodi Irwan Suparno Drajat Martianto Elpita Tarigan Elpita Tarigan Elpita Tarigan Elpita Tarigan Elpita Tarigan Ermi Girsang Eva Harlina Fitri, Arni Diana Ginting, Chrismis Novalinda Gunanti Gunanti . Hamdika Yendri Hamdika Yendri Hamdika Yendri Putra Hamdika Yendri Putra Hamzah Alfarisi Harry Murti I Nyoman Ehrich Lister I Nyoman Jaya Wistara IETJE WIENTARSIH Indra Bachtiar Irarang, Yusa Itje Wintarsih Jerica, Monica Silva Jurnila Sari Tanjung Kelvin Yaprianto L N Sutardi Leliana Nugrahaning Widi Leliana Widi Leliana Widi Lina Noviyanti Sutardi Lindiawati, Riris Maulana, M Ridha Mayasari, Ni Luh Putu Ika Mustika, Aulia A. Naufal Muharam Nurdin Nopen Meisaroh Nugraha, Arifin Budiman Nur Nabilla, Cintya Prasetyaningtyas, Wahono Puspitasari, Riris Putra, Hamdika Yendri Retno Wulansari Ridi Arif Rimbawan , Rindy Fazni Nengsih Rindy Fazni Nengsih Rindy Fazni Nengsih Risa Tiuria Rita Kartika Sari Sadiah, Siti Siti Sadiah Siti Sa’diah Sri Anna Marliyati Sri Rezeki Supiyani, Atin Surachmi Setiyaningsih Teresa Liliana Wargasetia The Fransiska Eltania Tutik Wresdiyati Vetnizah Juniantito Vetty Ramadhaniah Wahyu Widowati Wasmen Manalu Widi, Leliana Nugrahaning Wildan Mubarok Wiranti, Rahayu Woro Yendri, Hamdika Yusa Irarang Yusa Irarang Yusa Irarang Yusa Irarang