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All Journal Medula Wikrama Parahita : Jurnal Pengabdian Masyarakat Jurnal Kreativitas PKM Jurnal Literasiologi PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Jamu Indonesia JK Unila (Jurnal Kedokteran Universitas Lampung) Jurnal Mandala Pengabdian Masyarakat Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Jurnal Buana Farma Indonesian Journal of Biological Pharmacy Sains Medisina FASKES : Jurnal Farmasi, Kesehatan, dan Sains Jurnal Farmasi SYIFA Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Jurnal Praba: Jurnal Rumpun Kesehatan Umum Indonesian Journal of Jamu JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai
Oktoba, Zulpakor
Universitas Lampung
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POTENSI TANAMAN HERBAL SEBAGAI STIMULAN SISTEM SARAF PUSAT: LITERATURE REVIEW ARTICLE Suri, Nurma; Oktoba, Zulpakor; Yulianti, Mega Intan
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.960

Abstract

Energy drinks are consumed as supplement to increase energy and reduce fatigue. Herbal medicine has proven reduce fatigue in the body. This literature review aims to determine the types of herbal medicine that have properties as stimulants. This study used descriptive methode using the Population-Intervention-Controling-Outcome Framework. A literature search on studies published in the period 2012-2022 on the Google Scholar and Pub-Med using the keywords: stimulant, central nervous system, tonic, and herbal. Articles that cannot be accessed in full and herbal medicine that are not original from Indonesia will be excluded as samples. There were 1937 articles obtained based on the keywords used, a total of 91 articles met the inclusion criteria and 60 articles were excluded. Based on 30 articles reviewed, there are 31 types of herbal medicines that can increase stimulants with the most family is zingiberaceae and piperaceae. The combination of plant has a better stimulant effect than using the single plants. In vivo test method with the swimming endurance test as the most widely used. Flavonoid, alkaloid and terpenoid compounds are most likely to be effective as stimulants which have the same mechanism with caffeine through inhibition of Adenosine A1 receptors. This study shows there are 31 herbal medicine that have the potential to increase stimulants. Secondary metabolites which stimulant effects are flavonoids, alkaloids and terpenoids
Review: Efektivitas Daun Nangka Sebagai Antibakteri Purba, Gemi Sabrina; Oktoba, Zulpakor; Soleha, Tri Umiana; Adjeng, Andi Nafisah Tendri
Sains Medisina Vol 3 No 1 (2024): Sains Medisina
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/snsmed.v3i1.489

Abstract

Infeksi merupakan masalah kesehatan yang dapat berdampak buruk bagi kesehatan. Biasanya, penyakit infeksi diobati dengan antibiotik, tetapi penyalahgunaan antibiotik yang umum terjadi dapat menyebabkan resistensi, membuat bakteri menjadi tidak peka terhadap pengobatan tersebut. Nangka (Artocarpus heterophyllus Lam.) ialah salah satu tanaman yang sering dimanfaatkan oleh masyarakat sebagai obat tradisional untuk mengobati beragam penyakit akibat infeksi bakteri. Dalam review artikel ini dibahas mengenai komposisi metabolit sekunder yang terkandung dalam daun nangka guna memahami kemajuan riset terkait potensi daun nangka yang berfokus pada eksplorasi senyawa-senyawa bioaktif yang berperan dalam aktivitas antimikroba. Metode yang digunakan yaitu studi literatur dengan data yang didapat berasal dari artikel dengan alat pencarian informasi literature Google Scholar dan PubMed dengan rentang tahun 2017 sampai 2023. Hasil didapat dan disimpulkan bahwa ekstrak daun nangka mengandung senyawa-senyawa aktif seperti flavonoid, tanin, dan saponin. Escherichia coli, Salmonella typhi, Staphylococcus aureus, dan Propionibacterium acnes merupakan contoh bakteri yang perkembangbiakannya terhambat secara signifikan oleh ketiga senyawa yang diteliti.
Ethnopharmacy Study of Medicinal Plants Lampung Tribe in Pekon Tabuan Island, District Cukuh Balak, Tanggamus Regency, Lampung Province Oktoba, Zulpakor; Adjeng, Andi Nafisah Tendri; Romulya, Ari Irawan
Jurnal Jamu Indonesia Vol. 9 No. 1 (2024): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v9i1.286

Abstract

People in the Indonesian archipelago have long used medicinal plants as an alternative disease treatment. Tabuan Island is an area in Cukuh Balak District, Tanggamus Regency, Lampung Province, where most people are Lampung Peminggir /Pesisir tribe who still practice empirical medicine with local wisdom. Ethnopharmacy studies on Tabuan Island in the Lampung tribe have never been conducted and published. The study aimed to explore the knowledge of local communities regarding the types of medicinal plants for the search and development of new medicines. This research method includes area studies and descriptive studies in the form of ethnopharmacognosy-ethnopharmacology approaches in the Tabuan island community in 4 (four) villages or Pekon namely Pekon Sawang Balang, Pekon Suka Banjar, Pekon Kuta Kakhang, and Pekon Karang Buah used participatory observation methods and open interviews. The results showed that the Lampung Peminggir ethnic group on Tabuan Island still maintains ethnopharmaceutical traditions by utilizing plants used as medicine in 36 families of 76 species to treat diseases used singly or as a concoction accompanied by jampi. The most widely used plant families are Fabaceae, Zingiberaceae, Malvaceae, Meliaceae, and Poaceae. These medicinal plants in the Fabaceae family are most widely used to remedy mouth ulcers and skin problems such as tinea versicolor, ringworm, itching, acne, dandruff, diarrhea, and diabetes. Leaves are the most widely used plant parts, as much as 49.52%, and the least used plant parts are herbs, thallus, and fungi, while most of these plants are obtained in the garden. The most common way of processing medicinal plants is by stewing.
Article Review: Faktor-Faktor Yang Berhubungan Dengan Kejadian VAP (Ventilator-Associated Pneumonia) Pada Pasien Icu Yang Menggunakan Ventilator Mekanik Az Zahra, Ghina Nazhifah; Pardilawati, Citra Yuliyanda; Junando, Mirza; Oktoba, Zulpakor
Jurnal Farmasi SYIFA Vol 3 No 1 (2025): Jurnal Farmasi SYIFA
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/jfs.v3i1.609

Abstract

Ventilator-Associated Pneumonia (VAP) merupakan infeksi nosokomial pada saluran pernafasan yang terjadi pada pasien di ruang rawat intensif. Kejadian VAP dapat dipengaruhi oleh beberapa faktor risiko, antara lain: lama penggunaan ventilator mekanik, umur, perawatan oral hygiene, intubasi, komorbid, serta sedasi. VAP menjadi salah satu masalah kesehatan yang harus dihadapi oleh pasien dan tenaga kesehatan, khususnya pada pasien kritis terkait meningkatnya prevalensi kejadian morbiditas dan mortalitas akibat VAP. Article review ini bertujuan untuk dapat mengetahui faktor-faktor yang berhubungan dengan kejadian Ventilator-Associated Pneumonia (VAP) pada pasien ICU. Artikel ini diharapkan dapat memberikan wawasan baru dalam upaya pencegahan dan pengelolaan VAP. Studi ini menggunakan metode article review yang didapatkan melalui pencarian Google Scholar dan PubMed dengan kata kunci “Faktor Faktor yang Berhubungan dengan Kejadian VAP pada Pasien ICU yang menggunakan ventilator mekanik” berdasarkan kriteria inklusi. Hasil dari article review pada 8 artikel diketahui bahwa faktor faktor yang memengaruhi kejadian VAP pada pasien ICU yang menggunakan ventilator mekanik adalah banyak terjadi pada pasien yang berusia rentan, menggunakan ventilator mekanik lebih dari 48 jam, serta perilaku oral hyginie. Selain itu terdapat beberapa faktor lainnya yaitu jenis kelamin, pendidikan, intubasi, komorbid kejadian VAP, skor CPIS (Clinical Pulmonary Infection Score), sedasi, cuci tangan, dan pembedahan.
Analisis Aktivitas Antioksidan Ekstrak Daun Katang-Katang (Ipomea pes caprae) dengan Metode DPPH : Literature Review Tsania Zahra Taslima; Zulpakor Oktoba; Atri Sri Ulandari; Muhammad Iqbal
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 1 (2025): Januari : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i1.594

Abstract

Free radicals are reactive molecules that contribute to oxidative stress, triggering cellular damage and leading to degenerative diseases such as cancer, diabetes, and cardiovascular diseases. Antioxidants are required to neutralize free radicals and protect the body from oxidative damage. The leaves of Ipomoea pes-caprae (L.) R. Br. contain secondary metabolites, such as flavonoids and phenolics, which have potential antioxidant activity. This article aims to analyze the antioxidant activity of Ipomoea pes-caprae leaf extract using the DPPH method. The study employed a literature review approach using Google Scholar with specific keywords and 13 articles met the inclusion criteria with a  publication range from 2015 to 2025. The findings indicate that the extraction method and type of solvent significantly affect the effectiveness of antioxidant activity. Maceration and Soxhlet extraction methods were effective in isolating active compounds, particularly flavonoids and phenolics, while polar solvents such as ethanol and methanol produced better results compared to non-polar solvents. Antioxidant strength, determined by IC50 values, ranged from very strong to very weak. Therefore, it can be concluded that selecting the appropriate extraction method and solvent is crucial to maximizing the antioxidant potential of Ipomoea pes-caprae leaves as a natural antioxidant source for health and pharmaceutical applications.  
Potensi Aktivitas Antidiabetes Berbagai Jenis dan Varian Tanaman Mangga (Mangifera spp.) Agnes Monica Murisla; Zulpakor Oktoba; Femmy Andrifianie; Ramadhan Triyandi
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 2 (2025): April : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i2.595

Abstract

Diabetes mellitus is a chronic disease with a significantly increasing global prevalence, especially in developing countries. Current treatments use synthetic antidiabetic drugs that are generally expensive and have various side effects. This study aims to examine the potential of mango plants (Mangifera spp.) as antidiabetic agents through a systematic literature review. Literature searches were conducted through the electronic databases PubMed and Google Scholar using the keywords "Mangifera/mango" and "antidiabetic". From the search results, 25 relevant articles were obtained for further review, consisting of 15 articles on in vitro testing and 10 articles on in vivo testing. The search results identified 17 mango plant variants worldwide that have been shown to have antidiabetic activity. Each mango species has unique characteristics and different nutritional content and bioactive compounds. Various parts of the mango plant, including leaves, fruits, seeds, and bark, contain bioactive compounds such as flavonoids, tannins, saponins, and terpenoids. These compounds contribute to antidiabetic activity through several mechanisms, namely inhibition of α-glucosidase and α-amylase enzymes, increased insulin sensitivity, and reduced blood glucose levels. Mango plant secondary metabolites are not only effective, but also have the potential to be an alternative antidiabetic treatment that is more affordable and safe compared to synthetic drugs. It can be concluded that Mangifera spp. has great potential to be developed as an innovative diabetes therapy. Further research through clinical trials is needed to confirm its effectiveness as an antidiabetic agent.
Literature Review: Manfaat Tradisional, Kandungan Fitokimia, Aktivitas Farmakologis, dan Potensi Pengembangan Sediaan Antibakteri dari Tumbuhan Kakao (Theobroma cacao L.) Agaphe Suluh Brahmantio; Ramadhan Triyandi; Zulpakor Oktoba; Femmy Andrifianie; Muhammad Iqbal
Jurnal Praba : Jurnal Rumpun Kesehatan Umum Vol. 3 No. 2 (2025): Juni : Jurnal Praba : Jurnal Rumpun Kesehatan Umum
Publisher : STIKES Columbia Asia Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62027/praba.v3i2.362

Abstract

The cacao plant (Theobroma cacao L.) has long been used in traditional medicine and has been proven to contain phytochemical compounds such as polyphenols, flavonoids, alkaloids, and tannins, which exhibit pharmacological activities, including antioxidant, anti-inflammatory, and antibacterial properties. This study aims to review the potential development of antibacterial formulations based on cacao extract through a literature review. The method used is a qualitative descriptive analysis of national and international journals published in the last 10 years. The review results indicate that extracts from cacao seeds, fruit peels, and leaves are effective in inhibiting the growth of various pathogenic bacteria, both Gram-positive and Gram-negative. Various formulations such as gels, creams, lotions, soaps, toothpaste, and mouthwash have been developed with promising results. The utilization of the cacao plant as an antibacterial agent in pharmaceutical formulations holds great potential as a natural alternative in the healthcare field while also adding value to cocoa industry by-products.
Pendampingan Pembuatan Mykunas (Gummy Kulit Nanas) dalam Rangka Pemanfaatan Limbah Kulit Nanas di Pekon Gunung Terang, Kecamatan Bulok, Kabupaten Tanggamus Provinsi Lampung: Assistance in Making Mykunas (Pineapple Peel Gummy) in the Context of Utilizing Pineapple Peel Waste in Pekon Gunung Terang, Bulok District, Tanggamus Regency, Lampung Province Afriyani, Afriyani; Ulandari, Atri Sri; Oktoba, Zulpakor; Suri, Nurma
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 5 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i5.8837

Abstract

Utilization of Pineapple Peel (Ananas comosus L.) waste into jelly candy products for dental health. This PKM activity aims to socialize the Farmer Group community that pineapple peels can be utilized and processed into gummy candy, which is effective in improving dental health. Pineapple skin is rich in bromelain, vitamin C, cysteine protease, and phytochemical compounds in the form of alkaloids, phenols, tannins, flavonoids, saponins, and carbohydrates. Pineapple skin also contains a rich source of vitamin C and manganese, which can help fight inflammation in the gums and tissues. Manganese helps in the development, strengthening, and repair of bones and teeth. Bromelain and Vitamin C in pineapple skin have the potential to be developed into pharmaceutical products. The method used is focus group discussion (FGD) by presenting theory in lectures, completing pre-test and post-test questionnaires, and interactive questions and answers. The results of the analysis based on the results of the pre-test and post-test questionnaires showed that there was a slight increase in participants' understanding after taking the test. The average percentage of participants' pre-test was 78.12%, while the average percentage of post-test was 78.33%. Utilizing pineapple peel waste in gummy candy is effective in improving dental health and opening up business opportunities for the community. Pineapple skin, which is rich in bromelain and vitamin C, has not previously been utilized optimally. With this assistance, the Pekon Gunung Terang community can process pineapple peel waste into products that are valuable and beneficial for health and the local economy.
Studi Etnofarmasi Tumbuhan Berkhasiat Obat Suku Lampung Di Pekon Margakaya Kecamatan Pringsewu Kabupaten Pringsewu Novriana, Dina; Oktoba, Zulpakor; Oktarlina, Rasmi Zakiah; Triyandi, Ramadhan
Indonesian Journal of Biological Pharmacy Vol 4, No 3 (2024): IJBP (Desember)
Publisher : Department of Biological Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Etnofarmasi merupakan  ilmu hubungan antara kebiasaan sebuah kelompok masyarakat yang ditinjau dari farmasetiknya.  Untuk mempertahankan pengetahuan pengobatan tradisional khususnya suku Lampung, maka perlu dilakukan pendokumentasian dengan pendekatan etnofarmasi. Jenis penelitian ini observasional deskriptif  melalui pendekatan kuantitatif, dengan teknik pengambilan sampel yakni snowball sampling melalui wawancara dengan metode total sampling. Data diolah secara kuantitatif melalui perhitungan indeks nilai budaya atau ICS. Sebanyak 40 spesies tumbuhan dari 28 famili dimanfaatkan sebagai obat oleh suku Lampung di Pekon Margakaya. Tumbuhan yang paling banyak digunakan yaitu dari famili Zingiberaceae diantaranya kunyit (Curcuma longa), temulawak (Curcuma xanthorrhiza), kencur (Kaemferia galanga), jahe (Zingiber officinale), dan lengkuas (Alpinia galanga). Cara pemanfaatan tumbuhan obat yaitu direbus, ditumbuk, konsumsi langsung, dan diparut. Berdasarkan perhitungan ICS, tumbuhan yang memiliki nilai budaya paling tinggi yaitu kunyit (Curcuma longa) dengan nilai 90 kriteria signifikansi tinggi. Semakin tinggi nilai ICS maka semakin tinggi nilai budaya seperti halnya kunyit yang dipakai oleh masyarakat suku Lampung
Perbedaan Antara Tingkat Kepuasan Pasien Layanan Kefarmasian di Puskesmas Induk Natar dan Puskesmas Rajabasa Indah Lani Hartanti; Rasmi Zakiah Oktarlina; Zulpakor Oktoba; Asep Sukohar
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 3 (2025): Juli : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i3.787

Abstract

Background: Pharmaceutical services at primary health centers (puskesmas) play a vital role in supporting the quality of primary healthcare services. However, patient satisfaction with these services varies, influenced by factors such as service quality and demographic characteristics of the patients. In Lampung Province, the Induk Natar and Rajabasa Indah primary health care centers have different regional characteristics, which may influence patients perceptions and satisfaction with pharmaceutical services. Methods: This study employed an analytical observational method with a cross-sectional design. Samples were selected using systematic accidental sampling, with 100 respondents from each primary health care centers. Quantitative data were collected using the Servqual questionnaire and patient sociodemographic characteristics. Data were analyzed using the Mann-Whitney test and the Chi-Square test. Result: The reliability dimension showed the highest satisfaction level in both Induk Natar primary health care centers (90.10%) and Rajabasa Indah primary health care centers (94.05%). Conversely, the tangible dimension had the lowest satisfaction levels, with 88.60% in Induk Natar primary health care centers and 92.08% in Rajabasa Indah primary health care centers. A significant difference in patient satisfaction levels was found between the two health centers. However, no significant correlation was found between patient characteristics (age, gender, education, and occupation) and satisfaction levels (p-value > 0.05). Conclusion: Rajabasa Indah primary health care centers demonstrated a higher level of patient satisfaction compared to Induk Natar primary health care centers. A significant difference in satisfaction levels between the two centers was confirmed by the Mann-Whitney test.
Co-Authors Adrifianie, Femmy Afna Nur Afni Palogan Afriyani Afriyani Afriyani, Afriyani Agaphe Suluh Brahmantio Agnes Monica Murisla Ali, Nur Fitriana Muhammad Ambarwati, Endah Andi Nafisah Andrifianie, Femmy Ari Irawan Ari Irawan Ari Irawan Ari Wahyuni Asep Sukohar Asep Sukohar Athallah, Muhammad Muzhafar Athallah, Muhammad Muzhaffar Atri Sri Ulandari Az Zahra, Ghina Nazhifah Bayu Anggileo Pramesona Ciptaningrum, Sekar Rahmasari Ratna Endah Ambarwati Evy Afriyani Femmy Andrifianie Helmi Ismunandar Ihsanti Dwi Rahayu Ilyas Prabamukti Junando, Mirza Kurniawaty, Evi Lani Hartanti Mallarangeng, Andi Nafisah Tendri Adjeng Mega, Sri Wulan Muhammad Iqbal Mutiara Nauli Br. Sitinjak Novriana, Dina NUR AFRIYANI Parabi, Muhammad Iqbal Pardilawati, Citra Yuliyanda Purba, Gemi Sabrina Putu Ristyaning Ayu Rahmadhita, Elmira Rahmasari, Sekar Ramadhan Triyandi Ramadhan Triyandi Ramadhina, Farrasyifa Ramdini, Dwi Aulia Rani Himayani Rasmi Zakiah Oktarlina Risti Graharti Romulya, Ari Irawan Sangging, Putu Ristyaning Ayu Suharmanto Suri, Nurma T. Adjeng, Andi Nafisah Tri Umiana Soleha Triyandi, Ramadhan Tsania Zahra Taslima Wardhana, Donny Kesuma Widodo, Alya Rahmah Winnugroho Wiratman, Manfaluthy Hakim, Tiara Aninditha, Aru W. Sudoyo, Joedo Prihartono Yulianti, Mega Intan