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Pengaruh Asam dan High Energy Milling serta Karakterisasi Zeolit Alam Termodifikasi Mn Anghistra, Pradipta Ditya; Pardoyo, Pardoyo; Subagio, Agus
Greensphere: Journal of Environmental Chemistry Vol 3, No 2 (2023): Volume 3 Issue 2 Tahun 2023
Publisher : Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/gjec.2023.20974

Abstract

Telah dilakukan penelitian pengaruh zeolit alam dengan perlakuan asam dan high enrgy milling serta mengetahui karakter dari zeolit alam termodifikasi Mn. Penelitian ini bertujuan untuk memperoleh zeolit alam termodifikasi Mn dan mengetahui karakter akibat perlakuan asam dan high energy milling. Zeolit yang lolos ukuran 230 mesh dibagi menjadi dua bagian, pertama diberi perlakuan milling sedangkan yang kedua tanpa perlakuan milling. Kedua zeolit diaktivasi dengan HF 1% dan HCl 6M, selanjutnya ditambahkan MnCl2.4H2O 0,5M. Hasil penelitian menunjukkan adanya Mn pada kedua kerangka zeolit. Karakterisasi dengan FT-IR mengindikasikan terjadi dealuminasi ditandai dengan pergeseran bilangan gelombang dari 1049,78 cm-1 menjadi 1095,57 cm-1 dan 1080,14 cm-1 pada masing-masing zeolit dengan perlakuan  milling dan  tanpa milling. Analisis SEM diperoleh morfologi permukaan zeolit berbentuk bulat tak beraturan. Data SAA diketahui luas permukaan, volume pori dan diameter pori zeolit dengan perlakuan milling adalah 80,043 m2/g, 0,165 cc/g, dan 2,882 nm sedangkan zeolit tanpa perlakuan milling berturut-turut 141,946 m2/g, 0,170 cc/g, dan 2,693 nm.
The synthesis of nanosilver and carbamat to control of Anopheles in malaria endemic areas Raharjo, Mursid; Subagio, Agus; Sulistiyani, Sulistiyani
International Journal of Public Health Science (IJPHS) Vol 13, No 1: March 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i1.23453

Abstract

Malaria is a national and global problem that really needs attention and Indonesia is the second highest country with the highest number of cases 304,607 in 2021. The use of insecticides at inappropriate doses causes resistance to targets. The aim of this study was to analyze the toxicity of silver nanoparticles to adult Anopheles mosquitoes in malaria endemic areas as well as to determine the lethal concentration (LC50) and to project effectiveness in the lifetime. This research is experimental and uses a post-treatment with control design which was carried out in 4 stages from 2019-2022, which includes laboratory scale tests (2019), field laboratory scale tests (2020), ecological endemic area scale tests (2021), and lifetime tests (2022). Calculation of LC50 in nanosilver toxicity 5965 mg/l and Calculation of life time projections produces the formula Y=(-) 0.012Ln(X)+0.6933. Absorption of silver nanoparticles into the bodies of Anopheles sp. occurs through the spiracles and attacks the Ache enzyme in the central nervous system thereby stopping the working system of the mosquito which will then die. Nanosilver is a very effective herbal insecticide used as an effort to control malaria cases in endemic areas with the right dose and method. For life time, a dose of 1500 mg/l nanosilver effectively kills 74% of adult Anopheles sp mosquitoes on day 32 and it is projected that on 1 year the efficacy of nanomaterials still has an efficacy of 62%).
Topical Ointment Anredera cordifolia Leaves Ethanolic Extract-Loaded Nanochitosan Promotes Wound Healing in Hyperglycemic Rat Alfatinnisa, Zalfa; Andriyan, Mohammad Wahyu; Saputra, Muhammad Ragil; Astuti, Endah Puji; Sunarno, Sunarno; Isdadiyanto, Sri; Subagio, Agus; Jaya, La Ode Irman
Biosaintifika: Journal of Biology & Biology Education Vol. 16 No. 1 (2024): April 2024
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v15i1.1842

Abstract

Wound healing in hyperglycemia patients is still a challenge in the medical field. Bioactive compounds of binahong leaf extract can support the wound healing process. Nanoencapsulation of the extract can avoid oxidation and optimize drug delivery to target tissues. This study aimed to analyze the effect of nanochitosan encapsulated binahong extract ointment (NEBE/Oint) on the percentage of wound healing, angiogenesis, collagen density, and epithelial thickness in hyperglycemic rats. This study used 80 mg/kg streptozotocin-induced hyperglycemia rats injured in the back area. Rats were divided into P0 (0,9% NaCl), P1 (10% povidone-iodine ointment (PI/Oint)), P2 (10% NEBE/Oint), P3 (20% NEBE/Oint), P4 (30% NEBE/Oint). Phytochemical screening of binahong leaves extract showed positive results for flavonoids, alkaloids, saponins, and tannins. NEBE particle size was 169 nm with a size distribution of 0.2 and a zeta potential value of -40,2 mV. The results showed NEBE ointment had a significant effect when compared with negative control on wound healing hyperglycemic rats. The conclusion is that nanochitosan drug delivery has the potential as an alternative wound treatment. The novelty of this study is the use of nanochitosan to accelerate wound healing in hyperglycemic rats. The results of this study are expected to become a reference for new wound-healing methods in the medical field.
Students’ Habits and Identification of Bacteria on Inanimate Surface of Educational Setting Udijono, Ari; Subagio, Agus; Adi, Mateus Sakundarno; Widjanarko, Bagoes; Fauzi, Muhammad; Kusariana, Nissa; Sutiningsih, Dwi
JURNAL KESEHATAN LINGKUNGAN Vol. 16 No. 4 (2024): JURNAL KESEHATAN LINGKUNGAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkl.v16i4.2024.360-367

Abstract

Introduction: Diponegoro Clinic reported 29.1% of students seek infectious diseases treatment. Student habits in the classroom were thought to play roles in the presence of bacteria. Surfaces of inanimate objects in the classroom were potential source for bacteria. The research objectives were analyzing student’s habits and identifying bacteria on the surface of inanimate objects in the classroom. Methods: Four types of samples, including the surfaces of tables, chairs, flips of air conditioners, and floors were taken from 13 faculties at Universitas Diponegoro. Plate count agar media were used to isolate bacterial colonies, and PCR analysis was performed for DNA extraction and amplification. DNA Sanger sequencing techniques were used for genetic bacterial identification. The online questionnaire was used to assess student habits in the classroom. Two hundred students responded. Results and Discussion: Acinetobacter baumannii and Staphylococcus aureus were found in classrooms. These bacteria were associated with respiratory tract infections. This study revealed that 86.5% were between the ages of 17-21, 60.81% were from outside Semarang City, and 88.33% lived in Semarang City. About 60.81% of respondents studied in health sciences. Furthermore, it was reported that 66.67% of respondents were sick in the last few weeks, attended class despite being sick (72.52%), and coughed and sneezed in class (40.99%). Conclusion: Bacteria associated with respiratory tract infection were found. Students' habits in the classroom were potentially caused by the presence of these bacteria. The use of antibacterial agents could reduce the presence of bacteria on inanimate object surfaces.
Green Synthesis of Silver Nanoparticles as a Wound Healing Agent: a Systematic Review of the Biological Activities Priambodo, Galih; Samekto, Widiastuti; Subagio, Agus; Susanto, Hardhono; Dwiantoro, Luky
Indonesian Journal of Medicine Vol. 8 No. 1 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background:  The implication of nanotechnology includes silver nanoparticles to medical sciences, and has a revolutionary impact on therapeutic and diagnostics management. Many studies reported that silver nanoparticle (AgNPs) application can accelerate the wound healing process. This study aimed to systematically review the biological activities of silver nanoparticles as a wound-healing agent.Subjects and Method:  This article was a systematic review study conducted by searching for articles from online databases such as EBSCO, PubMed, Science Direct, and World Scientific. Populations: laboratory animals; Intervention: green synthesis of silver nanoparticles; Comparison: a standard ointment for wounds such as povidone-iodine, etc; Outcome: wound healing. The independent variable is the green synthesis of silver nanoparticles, and the dependent variable is wound healing. The inclusion criteria for this study were full articles using an experimental study, with the publication year until 2022. The data extraction was focused on the biological activities of silver nanoparticles and reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations for systematic reviews.Results:  A total of 8 articles reviewed in this study were from countries: Egypt, India, Saudi Arabia, Singapore, and China. The green synthesis of AgNPs was accomplished using a natural aqueous extract from leaves such as Azadirachta indica, Tridax procumbens, the combinations of Catharanthus roseus and Azadirachta indica, Scutellaria barbata, the fungus Fusarium verticillioides, or cyanobacterial platforms (ex: Phormidium sp., Synechocystis sp, and arthrospira sp polysaccharides). All studies were animal-based experimental with wounds infected with bacteria and inflicted in regards to the experiment. All trials resulted in favor of the AgNPs ointment treated group compared to the untreated group or the standard ointment group.Conclusion:  Our review suggested that all studies about the efficacy of AgNPs as wound-healing therapy showed positive results.Keywords:  biological activities, silver nanoparticles, wound healing.Correspondence: Galih Priambodo. Faculty of Medicine, Universitas Diponegoro. Jl. Prof. Sudarto, Tembalang, Kec. Tembalang, Kota Semarang, Central Java. Email: g2_37@yahoo.co.id. Mobile: 085229998999.Indonesian Journal of Medicine (2023), 08(01): 100-113https://doi.org/10.26911/theijmed.2023.08.01.10
Collaborative Academic Supervision as an Effort to Optimize Teacher Performance in the Independent Curriculum Subagio, Agus; Waruwu, Marinu; Enawaty, Eny; Halida, Halida
Riwayat: Educational Journal of History and Humanities Vol 7, No 4 (2024): October, Social Issue and Education
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jr.v7i4.41505

Abstract

This study explores the role of collaborative academic supervision in optimizing teacher performance within the framework of the Independent Curriculum. The Independent Curriculum, implemented in Indonesia, emphasizes student-centered learning and encourages teachers to adopt innovative teaching strategies. However, effective implementation requires a supportive environment, where academic supervision plays a crucial role. This research employs a qualitative approach, utilizing interviews and focus group discussions with educators and school administrators from various educational institutions. The findings reveal that collaborative academic supervision fosters a culture of shared responsibility among teachers, enhancing their professional development and instructional practices. Participants reported that engaging in collaborative supervision activities, such as peer observations and joint lesson planning, significantly improved their teaching efficacy and motivation. Furthermore, the study highlights the importance of building strong relationships among educators, as trust and open communication are essential for effective collaboration. The research also identifies challenges, including time constraints and varying levels of commitment among teachers, which can hinder the effectiveness of collaborative supervision. Based on these findings, the study recommends that schools prioritize collaborative academic supervision by providing structured training and allocating time for teachers to engage in these activities. This approach not only improves teacher performance but also contributes to a more dynamic and responsive learning environment for students. Overall, this research underscores the significance of collaborative academic supervision as a strategy to optimize teacher performance and enhance the quality of education within the Independent Curriculum framework.
Improved Thermal Stability of Silica Nanofluids Using Anionic Surfactants for Enhanced Oil Recovery Applications Rowi, Khasan; Ngadiwiyana, Ngadiwiyana; Subagio, Agus
Jurnal Kimia Sains dan Aplikasi Vol 28, No 5 (2025): Volume 28 Issue 5 Year 2025
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jksa.28.5.244-251

Abstract

Silica nanoparticles have shown great potential in the oil and gas industry sector, especially in applications for enhanced oil recovery. Silica nanofluids are widely used in EOR applications because they are inexpensive, easy to synthesize, environmentally friendly, can be surface modified, and provide high oil recovery rates. However, silica nanofluids have drawbacks in thermal stability and salinity at high temperatures, adversely affecting their application in oil reservoirs. In this paper, the effects of a surfactant sulfonate compound (SPU11) and a co-surfactant sulfosuccinate compound (SPU22) on the thermal stability of silica nanofluids at temperatures ranging from 60 to 100°C were investigated. Next, the silica nanofluids were analyzed for particle size using a particle size analyzer (PSA), wettability using a sessile drop contact angle, and oil recovery capacity using a core flooding test. The results showed that the silica nanofluid with 0.3% SPU11 and 0.3% SPU22 surfactant showed good thermal stability below 80°C for 3 months in 3 wt% brine; PSA analysis showed that the aggregate diameter was 52.86 nm; wettability analysis showed that the silica nanofluid had a contact angle of 60.8° to 36.6° and the core flooding results of silica nanofluid showed an oil in place recovery (OOIP) of 9.7%.
Implementation of Change Management by the Principal at the Driving School at State Senior High School 1 Segedong Subagio, Agus
Riwayat: Educational Journal of History and Humanities Vol 8, No 3 (2025): July, Social Studies, Educational Research and Humanities Research.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jr.v8i3.47733

Abstract

"Senior High School 1 Segedong faces challenges in managing change to improve the quality of education, particularly in dealing with resistance to new policies and limited resources. This study aims to analyze how the school principal implements change management in the Sekolah Penggerak (Driving School) Program at the school. A qualitative approach with a case study method was used to gather data through interviews, observations, and documentation. The results of the study indicate that effective communication is key to overcoming barriers to change, followed by enhancing the skills of educators and providing adequate motivation. Additionally, continuous evaluation supports the successful implementation of change, although resistance from some parties still exists. The positive impact of this change management is reflected in the transformation of the school culture, improved teacher performance, and better student learning outcomes. In conclusion, effective change management can create a more dynamic and adaptive educational environment at Senior High School 1 Segedong."
Penerapan Metode Material Requirement Planning Pada Sistem Informasi Persediaan Bahan Baku Pupuk Dolomite Dan Pupuk Calsium Di CV. Sambong Margo Utomo Subagio, Agus; Mashuri, Chamdan
Inovate Vol 7 No 2 (2023): Maret
Publisher : Fakultas Teknologi Informasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33752/inovate.v7i2.4117

Abstract

Fertilizer production activities require planning an adequate supply of raw materials to meet production needs so as not to experience shortages and excess stocks of raw materials. This research was conducted in the warehouse CV. Sambong Margo Utomo who experienced problems in the stock of raw material supplies due to the limited storage space they had and the data processing was still manual. The objectives to be achieved in this research are (1) To design an information system for the supply of raw materials for dolomite and calcium fertilizers (2) To build inventory system software using Material Requirement Planning (MRP) (3) To implement Material Requirement Planning (MRP) in planning the need for raw materials for fertilizer in CV. Sambong Margo Utomo. The results of this study, namely the Material Requirement Planning (MRP) method can be applied to an information system for the supply of raw materials for dolomite and calcium fertilizers in CV. Sambong Margo Utomo and testing of raw material inventory planning in January 2018 - December 2018 resulted in the frequency of orders, inventory costs and safety stock for each raw material. Keywords – Information System, Raw Material Inventory, Material Requirement Planning
Co-Authors Adi Darmawan Agung Cahyono Agus Setyawan Ahmad Aviv Mahmudi Alfatinnisa, Zalfa Andriyan, Mohammad Wahyu Anghistra, Pradipta Ditya Annisa Fadillah Ari Udijono Aslam Fatkhudin Bagoes Widjanarko Bayu Surarso Della Widya Puspita Djalal Er Riyanto Dwi Sutiningsih Dwiantoro, Luky Edy Supriyanto Eko Hidayanto Endah Puji Astuti, Endah Puji Eny Enawaty Erma Prihastanti Febio Dalanta Galih Priambodo, Galih Hadi Endrawati Halida Halida Hardhono Susanto Hella Arofah Hendri Widiyandari Hendri Widiyandari Hendri Widyandari Heri Sutanto Hermin Pancasakti Kusumaningrum Horasdia Saragih I Gusti Ngurah Antaryama I Nurhasanah Iis Nurhasanah Imam Misbach Indras Marhaendrajaya Indri Yuliastuti, Indri Jatmiko Endro Suseno Jaya, La Ode Irman Joko Sudarto Khasan Rowi Khasan Rowi M F Taftiari M. Imam Taufiq Maman Budiman Maman Budiman Marinu Waruwu Mashuri, Chamdan Mateus Sakundarno Adi, Mateus Sakundarno Maulidanir Rohman Metri Setyaningsih Metri Setyaningsih Moch. Abdul Mukid Moehamad Barmawi Moehammad Barmawi Mohammad Muhriz Muhammad Fauzi Muhammad Iskandar Zulkarnain Muhammad Nur Muhammad Zainuri Mursid Raharjo Musni Ahyani Musni Ahyani, Musni Mustafid Mustafid Ngadiwiyana M.Si. S.Si. Ngurah Ayu Ketut Umiati Nissa Kusariana Pardoyo Pardoyo Pardoyo, Pepen Arifin Pepen Arifin Priyono Priyono Priyono, R Hidayatuloh R. Yudianti Redemtus Heru Tjahjana Rike Yudianti Rike Yudianti Rini Budihastuti Ririn Sulpiani Rizky Bimanda Sakti Romi Buana Puja Pangestu Saputra, Muhammad Ragil Satriyo Adhy Silviana Silviana Siti Nandiyah, Siti Skolastika Dara Sabatini Sri Eny Suharini, Sri Eny Sri Isdadiyanto Sri Widodo Agung Suedy Subhan Subhan Subhan, Sudarno Sudarno Sudarto, Joko Sukirno Sukirno Sukirno Sukirno SULISTIYANI SULISTIYANI Sunarno Sunarno Tatang Wahyudi Tatang Wahyudi, Tatang Tri Windarti Udi Harmoko Vincensius Gunawan S.K. Weni Safitri Widianingsih Widianingsih Widiastuti Samekto Yohana Maya Kartikaratri Yundari, Yundari Yuvita Muliastuti