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All Journal Buletin Veteriner Udayana Buletin Udayana Mengabdi Jurnal Veteriner Indonesia Medicus Veterinus Journal of the Indonesian Tropical Animal Agriculture Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) Jurnal Medik Veteriner To Maega: Jurnal Pengabdian Masyarakat Advances in Tropical Biodiversity and Environmental Sciences Journal of Veterinary and Animal Sciences

Luh Made Sudimartini

Laboratorium Farmakologi Dan Farmasi Veteriner, Universitas Udayana

Author-ID : 388109

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Earth & Planetary Sciences Education Environmental Science Immunology & microbiology Medicine & Pharmacology Public Health Veterinary Other

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Pengaruh Konsentrasi dan Lama Perendaman Air Perasan Daun Pegagan terhadap Kualitas Daging Babi Ditinjau dari Uji Organoleptik Putu Henrywaesa Sudipa; Ida Bagus Ngurah Swacita; I Made Sukada; Luh Made Sudimartini; Kadek Karang Agustina
Buletin Veteriner Udayana Vol. 12 No. 2 August 2020
Publisher : The Faculty of Veterinary Medicine, Udayana University

Almost all meat on the market is contaminated by microorganisms. As a result of the contamination of microorganisms, it changes in color, odor, and consistency. This research aims to study the effect of various levels of concentration and soaking time of Pegagan (Centella asiatica L.) leaf juice and to study whether there is an interaction between concentration and soaking time of Centella asiatica L. juice on the quality of pork in terms of the organoleptic test. Soaking pork in the juice of Centella asiatica L. juice is done by inserting each piece of meat into eight glasses, which have been filled with control, 5%, 10%, and 15% concentration juice. Soaking is done for 5 minutes, and 10 minutes then the meat is drained for 15 minutes, then an organoleptic test is performed and analyzed by variance. The results of the concentration had a significant effect (P<0.05) on changes in color, odor, and consistency of meat. While the soaking time had a significant effect (P<0.05) on the smell of meat but no significant effect (P>0.05) on the color and consistency of pork. And also, there is no interaction between concentration and soaking time.

Efek Pemberian Sediaan Salep Ekstrak Daun Binahong secara Dermal pada Luka Insisi Putu Oka Samirana; Luh Made Sudimartini; I Wayan Juli Sumadi; Putu Dessy Wilantari
Buletin Veteriner Udayana Vol. 14 No. 2 April 2022
Publisher : The Faculty of Veterinary Medicine, Udayana University

Luka insisi merupakan luka yang terjadi karena teriris oleh instrumen yang tajam, misalnya luka yang terjadi setelah pembedahan atau operasi. Penelitian ini bertujuan untuk mengetahui efek pemberian sediaan salep ekstrak daun Binahong pada penyembuhan luka insisi. Daun Anredera scandens (L.) Moq. diekstraksi menggunakan etanol 70%, dan ekstraknya dibuat salep dengan basis adeps lanae dan vaselin album. Sebanyak 35 ekor tikus putih betina galur wistar umur 2-3 bulan dengan bobot 200 g dan diaklimatisasi selama satu minggu, dikelompokkan menjadi 7 kelompok perlakuan. Semua kelompok dibuat luka insisi pada bagian punggung sejajar tulang vertebra, kecuali pada kelompok normal. Setiap hari diberikan salep sebanyak dua kali sehari sebanyak 250 mg. Parameter yang diamati dari histopatologi kulit setelah diberikan salep adalah infiltrasi sel radang dan pembentukan kolagen Hasil penelitian menunjukkan bahwa pemberian salep ekstrak etanol daun A. scandens (L.) Moq. menunjukkan bahwa pada hari ke-21 masih terdapat sel radang yang tidak berbeda bermakna (p>0,05) pada semua kelompok dan pada konsentrasi ekstrak 40% terjadi pembentukan kolagen yang berbeda bermakna (p<0,05). Disimpulkan salep ekstrak etanol daun A. scandens (L.) Moq. belum mampu mengurangi sel radang setelah 21 hari perlakuan dan pada konsentrasi 40% menunjukkan pembentukan kolagen paling signifikan.

Pengaruh Pemberian Propolis Terhadap Gambaran Histopatologi Ginjal Tikus Putih yang Diberikan Parasetamol Dosis Tinggi Elti Febilani; I Ketut Berata; Samsuri Samsuri; I Made Merdana; Luh Made Sudimartini
Buletin Veteriner Udayana Vol. 9 No. 1 Pebruari 2017
Publisher : The Faculty of Veterinary Medicine, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (593.432 KB)

The purpose of this study is to determine the effect of propolis on kidney histopathological representation of white rats were given the toxic dose paracetamol. 25 male rats males were used in this study who were divided into 5 groups, control group (P0) without treatment, group 1 (P1) that was given paracetamol doses 250mg/kg, group 2 (P2), group 3 (P3), and group 4 (P4), given paracetamol dose of 250mg / kg and propolis added 0.25 ml (P2), 0.50 ml (P3), and 0.75 ml (P4). Paracetamol and propolis were given orally by mixing it into the water provided ad libitum for 10 days. Then performed a necropsy and kidney were taken aseptically for making of histopathology preparations with hematoxylin eosin (HE) staining. The examined variables were fatty degeneration and necrosis in the proximal tubules of the kidney. Results indicate that fatty degeneration and necrosis were showed in treatment P1, while the entire treatment P2, P3, and P4 show the repair from the damage caused by the paracetamol. Treatment P4 gives the best results in reducing the effects of the paracetamol. Kruskal-Wallis showed a significant difference from fatty degeneration and necrosis of the tested group. From this study it can be concluded that the propolis with dose 0.75 ml giving better protection than 0.25 ml and 0.50 ml dose.

Efektifitas Fraksi Kromotografi Ekstrak Buah Pare (Momordica Charantia) Terhadap Peningkatan Bobot Badan Tikus Kondisi Diabetes Mellitus Cyrilus Jefferson Bour; Luh Made Sudimartini; I Nyoman Suartha
Buletin Veteriner Udayana Vol. 11 No. 2 Agustus 2019
Publisher : The Faculty of Veterinary Medicine, Udayana University

The purpose of this research is to identify the effects the provision of faction chromatography extract of Momordica charantia on the increase in body weight white male diabetes mellitus rats. Momordica charantia extracted using ethanol 70%, then partitioned with n-hexane, and continued with thin layer chromatography, to achieve five factions. 40 white male rats (Rattus novergicus) of 3-4-month-old with 150-200 g of body weight were adapted for two weeks, arranged to eight the treatment groups which each group consists of 5 rats. Every treatment was checked blood glucose levels and the average of body weight on the day -1, 0 (hiperglikemia rats), 4, 11, 18. The condition of diabetes mellitus in every group except the negative control that was made by injecting streptozotocin (STZ) on day 0 at a dose of 45 mg/kg. The results of the study showed that the faction 1 and 5 pare fruit doses 50 mg/kg bb able to increased high significantly weight mice on the day 4th.. equal such as extract ethanol of pare fruit. Faction 2, 3 and 4 pieces pare with the same dosage are able to increase high significantly weight on the day 11th century. In conclusion, the results showed faction treatment 1 and 5 were faster respond of increasing weight compared with other fractions.

Gambaran Darah Anjing Yang Diinjeksi Xilasin-Ketamin Secara Subkutan Rosni Lumban Gaol; I Gusti Ngurah Sudisma; Ida Bagus Komang Ardana; Luh Made Sudimartini
Buletin Veteriner Udayana Vol. 8 No. 1 Pebruari 2016
Publisher : The Faculty of Veterinary Medicine, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (133.247 KB)

This study aims were to observe the effect of repeated injection of xylazine-ketamine subcutaneously to total erythrocytes, hamoglobin and hamatocrit levels of local dogs. Experimental animals used were 24 local dogs aged 1-2 years with a weight of 10-15 kg. The dogs were divided into three groups. First group as control, while group 2 in xylazine-ketamine combination injection with doses (2 and 10 mg / kg) and group 3 was injected xylazine-ketamine separated, with xylazine dose (2 mg / kg) and ketamine with dose (10 mg / kg) subcutaneously. Blood sampling conducted before anesthesia and post-anesthesia (recovery period) through the femoral vein. Examination of total erythrocyte used Neubauer methods, Sahlimethods used for examination of hamoglobin levels and examination of hematocrit used Microhematocrit methods. The results showed that there was no significant difference to total erythrocytes, haemoglobin and hamatocrit levels in treatment repeated injection of xylazine-ketamine combined or separated with the control group. From these results it can be concluded that repeated injections of ketamine with xilasin-xilasin dose (2 mg / kg) and ketamine (10 mg / kg BW) safety specifications to total erythrocytes, hamoglobin and hamatocrit levels and either used as an anesthetic in dogs.

Aktivitas Alanin Aminotransferase Dan Aspartat Aminotransferase Sapi Bali Terinfeksi Fasciola Gigantica Anak Agung Gde Oka Dharmayudha; Ida Bagus Dimas Kusumadarma; Ida Bagus Komang Ardana; Made Suma Anthara; I Wayan Nico Fajar Gunawan; Luh Made Sudimartini; Kadek Karang Agustina
Buletin Veteriner Udayana Vol. 10 No. 1 Pebruari 2018
Publisher : The Faculty of Veterinary Medicine, Udayana University

Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST) are aminotransferase group enzymes which often used as parameters of liver damage. The purpose of this study is to determine the effect of Fasciola gigantica infections in bali cattle on the activity of ALT and AST. The materials used were 60 bali cattle blood samples consisting of 30 samples of blood were infected Fasciola gigantica and 30 blood samples were not infected with Fasciola gigantica. Blood samples were taken at the time of the slaughter placed in non EDTA tube. Data were analyzed using Independent Samples T-Test. The results showed a mean ALT levels in the blood of infected Bali cattle Fasciola gigantica was 78.73 U/L. It was not significant on the increase in ALT levels compared with uninfected bali cattle Fasciola gigantica 57.23 U/L, While the average AST levels in the bali cattle blood which were infected by Fasciola gigantica was 108.43 U/L. It was highly significant increased AST compared with non-infected Bali cattle Fasciola gigantica 78.13 U/L.

Perhatian Pemilik Anjing Dalam Mendukung Bali Bebas Rabies I Nyoman Suartha; Made Suma Anthara; Ni Made Rita Krisna Dewi; I Wayan Wirata; I Gusti Ngurah Kade Mahardika; Anak Agung Gde Oka Dharmayudha; Luh Made Sudimartini
Buletin Veteriner Udayana Vol. 6 No.1 Pebruari 2014
Publisher : The Faculty of Veterinary Medicine, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (47.219 KB)

Penelitian ini bertujuan untuk mengetahui perhatian pemilik anjing dalam mendukung Bali bebas Rabies. Penelitian dilakukan pada bulan Desember 2010, di Desa Kukuh Tabanan, Desa Jagapati Badung, dan Desa Seraya Karangasem dengan jumlah responden sebanyak 500 orang. Cara pengumpulan data yang digunakan dalam penelitian ini adalah wawancara dengan panduan daftar pertanyaan yang ada pada kuisioner. Hasil penelitian menunjukkan bahwa Jumlah kepemilikan anjing dari satu ekor sampai 4 ekor. Masyarakat memelihara anjing sebagian besar dengan tujuan untuk menjaga rumah (77,6%). Perhatian masyarakat pemilik anjing terhadap kesehatan dan perawatan kesehatan anjingnya, dilihat dari memandikan anjing, jumlah pemberian pakan, dan memeriksakan anjingnya ke dokter hewan masih rendah. Anggota keluarga yang sering berinteraksi (memberikan pakan, memandikan) dengan anjing adalah ayah. Responden yang menjawab anjing bisa dipegang pemilik sebanyak 93,6%. Berdasarkan atas jenis kelamin, masyarakat sebagian besar memelihara anjing jantan (84,8%). Anjing yang dipelihara dengan cara dilepas (64%). Kesimpulan dari penelitian ini adalah perhatian masyarakat dalam memelihara anjing dalam upaya mendukung Bali bebas rabies masih rendah. Disarankan perlu dilakukan kegiatan sosialisasi dan edukasi tentang pemeliharaan anjing pada masyarakat.

Efektivitas Vitamin E dan Deksametason pada Otak Tikus Putih Afrizal Choirul Umam; I Ketut Berata; Samsuri Samsuri; I Wayan Sudira; Luh Made Sudimartini; I Made Merdana
Buletin Veteriner Udayana Vol. 10 No. 1 Pebruari 2018
Publisher : The Faculty of Veterinary Medicine, Udayana University

Provision of dexamethasone for the long term and large doses may cause disturbances in the brain. To prevent disruption to the brain, it needs antioxidant such as vitamin E. The aims of this study is to prove the administration of dexamethasone cause interference on white rat brain and determine the effects of vitamin E supplementation in preventing the side effects of dexamethasone in the brains of rats. This study used 25 male rats were divided into 5 groups, namely negative control was only given food and drink, positive control is given dexamethasone at a dose of 0.13 mg/kg bw, P1 given dexamethasone 0.13 mg/kg of body weight and vitamin E at a dose of 100 mg/kg bw, P2 given dexamethasone 0.13 mg/kg bw and vitamin E at a dose of 150 mg/kg bw, P3 given dexamethasone 0.13 mg/kg bw and vitamin E at a dose of 200 mg/kgbw. Treatment was given for 14 days, then the experimental animals necropsied. Brain tissue was taken and processed for making histopathology preparations using hematoxylin-eosin staining. Variables examined include perivascular edema lesions and congestion. The result found a significant difference between negative and positive control. The mean score improvement of brain damage was not significantly different between the treatment P1, P2, and P3. P1 treatment groups showed mean score approached the negative control. The conclusions of this research was the dexamethasone caused histopathological changes to rat brains. Supplementation of vitamin E up to doses of 200 mg /kg of body weight have not been able to reduce the side effects of dexamethasone on the brain.

Kesembuhan Lesi Dermatitis Kompleks dengan Pemakaian Krim Herbal Putu Adrian Junaedi; I Nyoman Suartha; Luh Made Sudimartini
Buletin Veteriner Udayana Vol. 12 No. 1 Pebruari 2020
Publisher : The Faculty of Veterinary Medicine, Udayana University

Dermatitis is a term of inflammation that occurs in the skin, resulting from infection with microorganisms and genetic factors, skin resistance and metabolism. The purpose of this study was to determine the healing of lesions in dogs that suffering from complex dermatitis that were given herbal cream preparations. The herbal cream used is derived from neem, pegagan and soursop plant extracts. This study used 4 dogs divided into 2 groups. Group A was 3 dogs that were given herbal cream preparations for 15 days and Group B was 1 dog as a control without herbal cream. Recovery of lesions was observed starting from day 0 to day 15. The data obtained were tested by the Wilcoxon test and analyzed descriptively. The results showed that in group A which was given herbal cream experienced a cure rate of lesions faster than group B without herbal cream. The administration of herbal cream had a significant effect (P<0.05) on dogs that suffering from complex dermatitis. Conclusion and the administration of herbal creams can accelerate healing of lesions in dogs that suffering from complex dermatitis.

Evaluasi Stabilitas Krim Ekstrak Nimba, Pegagan, dan Sirsak untuk Pengobatan Dermatitis pada Anjing I Nyoman Suartha; Luh Made Sudimartini; Ni Putu Ayu Dewi Wijayanti
Buletin Veteriner Udayana Vol. 13 No. 2 Agustus 2021
Publisher : The Faculty of Veterinary Medicine, Udayana University

This study aims to evaluate the stability of herbal extract creams with a combination of neem leaves, gotu kola, and soursop extract to cure dermatitis complex in dogs., This herb extract has been able to inhibit in vitro the growth of bacteria that cause dermatitis. This research was conducted in the Laboratory of Non-Sterile Formulation and Technology at the Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Udayana University. Cream preparations were made in three formulations; each formulation was evaluated for stability at room temperature. Evaluation of the stability of cream includes organoleptic test, homogeneity test, pH test, adhesion test, spreadability test, and viscosity test. The results showed the cream was stable at room temperature for one month and the stable formula was formula 1. It can be concluded that the herb of formula 1 extract cream was stable at room temperature for one month.

Co-Authors Afrizal Choirul Umam Ainul - Hidayah Amelia Avianti Saritjang Anak Agung Ayu Mirah Adi Anak Agung Gde Jaya Wardhita Anak Agung Gde Jaya Wardhita, Anak Agung Gde Jaya Anak Agung Gde Oka Darmayudha Anak Agung Gde Oka Dharmayuda Anak Agung Gde Oka Dharmayudha Anak Agung Istri Sri Wiadnyani Anak Agung Sagung Kendran Anastasia Bhala Archie Leander Maslim Boro, Saptarima Eka Estiani Cahyaniarta, I Kade Candra Cyrilus Jefferson Bour Desak Nyoman Dewi Indira Laksmi Elsa Hidayati Elti Febilani Fernandes, Nuno Firdaus, Ihsanul Genta Dhamara Adam Putranto Gunawan, I Wayan Nico Fajar Gunawan, I. W. N. F. Heparandita, Ananda Agung Dextra I Gusti Agung Gede Putra Pemayun I Gusti Ketut Suarjana I Gusti Made Krisna Erawan I Gusti Ngurah Bagus Trilaksana I Gusti Ngurah Kade Mahardika I Gusti Ngurah Sudisma I Gusti Putu Tovan Mahottama I GustiKetut Suarjana I Ketut Anom Dada I Ketut Berata I Ketut Puja I Made Agus Wiranata I Made Dira Swantara I Made Kardena I Made Merdana I Made Sukada I Nyoman Suartha I W. F. Gunawan I Wayan Fandhi Wibawa Lostapa I Wayan Gorda I Wayan Juli Sumadi I Wayan Sudira I Wayan Wirata I Wayan Wirata Ida Bagus Dimas Kusumadarma Ida Bagus Komang Ardana Ida Bagus Ngurah Swacita Ida Bagus Oka Winaya Ida Bagus Windia Adnyana Iwan Harjono Utama Jayawardhita, Anak Agung Gde K. K. Agustina Kadek Karang Agustina Ketut Budiasa Komang Sri Gilang Airlangga Laksmi, D. N. D. I Luh Dewi Anggreni Luwis, Jeremy Christian Made Suma Anthara Made Suma Anthara Megariyanthi, Ni Putu Arie Mufa, Romy Muhammad Dary Ni Kadek Eka Widiadnyani Ni Kadek Laura Sastrawan, Ni Kadek Laura Ni Luh Eka Setiasih Ni Luh Putu Kusuma Clara Dewinda Ni Made Rita Krisna Dewi Ni Nyoman Werdi Susari Ni Putu Ayu Dewi Wijayanti Ni Putu Trisna Asih Pratama Putra, I Wayan Dwika Putra, Komang Darma Yudha Putrawan, Baja Sadhayu Putri, Adelia Putri, Ayu Chitra Adhitya Putu Adrian Junaedi Putu Dessy Wilantari Putu Devi Jayanti Putu Henrywaesa Sudipa Putu Oka Samirana Putu Suastika Rahim, M. Andry Rohmandhani, Roby Rosni Lumban Gaol Sakura, Yoakim Wilson Samsuri , Samsuri Samsuri Samsuri Samsuri Saweng, Cikal Farah Irian Jati Sawitajaya, I Made Sewoyo, Palagan Senopati Sitohang, Martina Tiodora Steven Dwi Purbantoro Sukernayasa, I Wayan Sutadisastra, Nisha Aisya Theresia Ene Wayan Herry Gumawan Widyanti, Agnes Indah Wirawan, I Gede Yoana Pratiwi Clara Pakpahan

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