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The Paradox of Negative Antibody Screening and Positive Crossmatching: Implications for Transfusion Safety in a Developing Country Suryanto; Adang Muhammad Gugun
Open Access Indonesian Journal of Medical Reviews Vol. 5 No. 6 (2025): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v5i6.811

Abstract

Modern antibody screening is a pillar of transfusion safety, intended to prevent hemolytic reactions. However, its ultimate effectiveness, particularly in diverse populations within developing nations where abbreviated crossmatch protocols are not feasible, remains a critical question. This study investigates the "safety gap" between negative screening results and final patient-donor compatibility, aiming to quantify the incidence of serological incompatibility detected by mandatory crossmatching in a tertiary hospital in Indonesia. A descriptive, cross-sectional study was conducted from March to June 2024 at the Blood Bank of PKU Muhammadiyah Yogyakarta Hospital. A total of 299 donor-recipient pairs were analyzed via total sampling. Donor units were screened for irregular antibodies using an automated Column Agglutination Technology (Gel Test) with comprehensive three-cell panels. Subsequently, major and minor crossmatches for all pairs were performed using a Gel Test-based Indirect Antiglobulin Test (IAT) incubated for 15 minutes at 37°C. All 299 donor samples (100%) yielded negative results for irregular antibodies during screening. However, the final crossmatch revealed serological incompatibilities. Major crossmatching (patient serum vs. donor cells) identified incompatibility in 4 cases (1.34%). Minor crossmatching (donor serum vs. patient cells) showed a significantly higher rate of incompatibility, found in 21 cases (7.03%). The predominant blood component transfused was Packed Red Cells (91.97%). In conclusion, the findings demonstrate a significant paradox where a substantial rate of serological incompatibility is only detected by the final crossmatch. This study quantitatively confirms that antibody screening alone is insufficient to guarantee blood compatibility. These results challenge the safety of adopting abbreviated crossmatch protocols in this setting and affirm that the physical crossmatch remains an indispensable, non-negotiable safeguard. This provides critical, region-specific evidence for strengthening hemovigilance systems and reinforcing transfusion policies in Indonesia and other resource-limited nations.
Pengabdian Masyarakat Diaplikasikan dalam Yayasan Darul Falah Tulungrejo Pare Kediri Azizah, Salsa Nur; Bagas, Mafaza; Suryanto
IKHLAS: Jurnal Pengabdian Dosen dan Mahasiswa Vol. 3 No. 3 (2024): IKHLAS: Jurnal Pengabdian Dosen dan Mahasiswa
Publisher : Indra Institute Research & Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58707/ikhlas.v3i3.1048

Abstract

This service aims to analyze the role of the Darul Falah Al-Qur'an Education Park (TPQ) in Tulungrejo Village, Pare, Kediri in forming the character of students through mentoring, continuous training and advice in forming religious, independent and communicative character in children through learning activities and internalization of Islamic values. TPQ plays an important role through habituation activities to foster positive religious character from an early age based on Islamic teachings. Achieving success in learning depends on the material presented and the methods used in learning. But in this case it is definitely not an easy thing. The problem in this case is the lack of human resources and the lack of consistency when implementing learning methods.
EFFECT OF STATIC THERMAL TENSIONING AND PREHEATING ON ANGULAR DISTORTION IN FCAW WELDED SS400 STEEL CORNER JOINTS Susilo, Sugeng Hadi; yudiyanto, eko; Setiawan, Agus; Khambali, Khambali; Suryanto; Alauddin, Falih
Logic : Jurnal Rancang Bangun dan Teknologi Vol. 24 No. 2 (2024): July
Publisher : Unit Publikasi Ilmiah, P3M, Politeknik Negeri Bali

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31940/logic.v24i2.39-48

Abstract

FCAW welding is an automated welding process that employs a wire roll electrode to melt metal, using flux or powder within the electrode's core for protection. A common issue with FCAW welding is the occurrence of angular distortion and alterations in the length and width dimensions, particularly in thin plate iron materials, due to residual stresses from the welding process. This research aims to assess the impact of static thermal tensioning, preheating, and their combination on angular distortion in SS400 steel corner joints during FCAW welding, considering heat input during welding. True experimental research methodology was employed, with variations in preheating temperatures of 200°C, 250°C, 300°C, static thermal tensioning at 150°C, 200°C, 250°C, transient thermal tensioning at 150°C, 200°C, 250°C, and a reference method with no treatment to determine the welding approach that minimizes angular distortion. The material used was 3mm thick SS400 steel. Data analysis was performed using Minitab 18 software and the One-Way Anova method. The research results indicate a significant influence of static thermal tensioning, preheating, and their combination on angular distortion. The optimal welding methods identified are preheating-static thermal tensioning at 89°55', preheating-transient thermal tensioning at 89°50', static thermal tensioning at 150°C at 89°45', transient thermal tensioning at 150°C at 89°40', and preheating at 200°C at 89°35'.
Makna Marga bagi Mahasiswa Suku Batak sebagai Identitas Diri di Perantauan Hutasoit, Dame Triulina; Suryanto
ILMU PSIKOLOGI Vol 12 No 2 (2025)
Publisher : Fakultas Psikologi Universitas Yudharta Pasuruan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35891/jip.v12i2.5960

Abstract

Marga merupakan tanda pengenal dan identitas khas pada masyarakat suku Batak yang memiliki peran penting dalam kehidupan sosial, termasuk bagi mahasiswa Batak yang merantau. Penelitian ini bertujuan untuk memahami peran marga dalam membentuk identitas diri mahasiswa Batak di perantauan. Pendekatan yang digunakan adalah kualitatif dengan metode fenomenologi. Subjek penelitian berjumlah dua orang yang dipilih berdasarkan kriteria tertentu. Data dikumpulkan melalui wawancara dan observasi, kemudian dianalisis dengan tahapan pengumpulan data teks, initial coding, kategorisasi tema, penghitungan frekuensi, interpretasi makna, dan penyajian temuan. Hasil penelitian menunjukkan bahwa marga berperan sebagai social identity, communal cohesion, collective pride, moral cognition, esteem needs, dan self-expression. Temuan ini memperkuat pemahaman bahwa marga merupakan elemen penting dalam pembentukan identitas sosial mahasiswa Batak di lingkungan multikultural.
Co-Authors Adang Muhammad Gugun Adang Muhammad Gugun, Adang Muhammad Agung Trilaksono Agus Setiawan Alauddin, Falih Albert Almira, Anissa Putri Amaluddin Sope Anggraeni, Rosmita Apriliani, Angeline Paskaria Ardian Rizal Aris Budiarto Azizah, Salsa Nur Bagas, Mafaza Basuki, Dewy Beti Pudyastuti Budy Wiryawan Cholid Tri Tjahjono Candra Dadang Dally Dewi Latifatul Ilma Eko Yudiyanto Emanauli Evi Gravitiani, Evi Faisal Akhmal Muslikh Fita Sari, Fita Ghazyarda Aqilah Setya Hasriati Nasution Helman Nur Yusuf Hikmawan Wahyu Sulistomo Hutasoit, Dame Triulina Ika Setyo Rini Ilmi, Iva Nur Iqnatius Tri Hagiyatno Irfan Yulianto Isnubroto, Danang Junaidi Junaidi Junun Sartohadi Khambali, Khambali Lestari, Eviadi lukman Nulmunir Mahiswara Margettya Marjabessy, Mutiara Melyawati Mifetika Lukitasari Moh. Afnan Rahmaturrahman Mohamad Natsir Mohammad Saifur Rohman Mudrajat Kuncoro Mukhsin, Moh. Mu’awanah, Isnin Aulia Ulfah Nahdhia, Nadhifatun Nayla, Muthia Rahman Nugroho, Septiawan Nurlinda Parmasari, Damairia Hayu Permana, Sofiyan Muji Regi Fiji Anggawangsa Reko Priyonggo Rekso Negoro, Widigdo Retno Widodo Dwi Pramono Rindy Permana, Annes Rodli, Muhammad Rosmala, Mila Ashri Rozany, Farida Rubai, Windri Lesmana Saad, Asmadi Santi, Dyan Evita Sari, Fipit Nurika Sembiring, Rahmat Widya Setyaji, Hajar sintara, sindu Suartana, Dewa Putu Sudewi Sukamta Sukamta sultan Sumardi Susilawati, Delis Susilo, Sugeng Hadi Taruna Shafa Arzam, Taruna Shafa Watmah, Sri Werdiningsih, Wiwik Wulansari, Oktufiani Dwi Yoli Anathasia Yulisti, Maharani Yuristi Mahardika, Yesika Yusfaneti