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DEVELOPMENT AND VALIDATION OF A HPLC METHOD FOR DETERMINATION AND QUANTIFICATION OF RUBRAXANTHONE IN STEM BARK EXTRACT OF MANGOSTEEN Meri Susanti; Dwisesaria Irma Lena; Dachriyanus Dachriyanus
Indonesian Journal of Pharmacy Vol 25 No 4, 2014
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (940.042 KB) | DOI: 10.14499/indonesianjpharm25iss4pp237

Abstract

Rubraxanthone is one of antibacterial  and antioxidant compound which is isolated from stem bark of mangosteen (Garcinia mangostana Linn.). The precise method for analysis of plant constituents is normally a reverse-phase high performance liquid chromatographic (RP-HPLC). Development and validation of a RP-HPLC method for chromatographic separation was carried out on a reversed-phase column Shimadzu ®  Shimp-pack VP – ODS (4.6x250mm) using an isocratic mobile phase of  0.4% formic acid - acetonitrile at  a flow rate 1mL min-1, and detection was  with a UV detector. The linearity of  the proposed method was found in the range of 2.5-25μg/mL-1 with regression coefficient 0.999. Intraday precision studies showed the relative standard deviation ≤1.58% and  inter-day ≤3.20%. Accuracy of the method was determined by a recovery study conducted at 3 different levels, and the average recovery was 102.18%. The Limit of Detection Limit of Quantitation (LOQ) and were 0.47 and 1.56μg/mL-1.The contents of rubraxanthon in the crude was 0.23±0.07%w/w.
Farmakokinetika dan Bioavailability Senyawa Golongan Santon Revew Komprehensif Meri Susanti
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 2 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (223.776 KB) | DOI: 10.51887/jpfi.v8i2.780

Abstract

The use of herbs for treating various ailment dates back several centuries. Evidence-based verification of the efficacy of Herbal medicines is still frequently lacking. Of particular interest is the question of bioavailability to assess to what degree and how fast compounds are absorbed after administration of herbal. Of further interest is the elucidation of metabolic pathways, and the assessment of elimination routes and their kinetics. These data become an important issue to link data from pharmacological assays and clinical effects. A better understanding of the pharmacokinetics and bioavailability of phytopharmaceuticals can also help in designing rational dosage regimens. To provide provide a detailed picture on ADME parameters (absorption, distribution, metabolism, and excretion) of some xanthone active compound, this article reviews the pharmacokinetic profile of 7 xanthones bioactive compound from the year 2009 onward.
Program Layanan Konsultasi Psikologis pada Penyintas Long Covid-19 Diny Amenike; Egha Febrianingsih; Sylvia Dewiriza; Haznaz Dhiya Ulhaq Z.N.; Cikita Aidha Putri; Rozi Sastra Purna; Dwi Puspasari; Septi Mayang Sarry; Nila Anggreiny; Meria Susanti; Amatul Firdausa Nasa; Siska Oktari; Yantri Maputra; Tri Rahayuningsih; Fitria Rahmi; Mafaza Mafaza; Izzanil Hidayati; Liliyana Sari
Warta Pengabdian Andalas Vol 29 No 2 (2022)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.29.2.94-100.2022

Abstract

Survivors of Covid-19 can still experience symptoms such as being still infected with a virus known as Long Covid-19. Covid-19 survivors with long Covid-19 experience physical and psychological disorders. Psychological disorders include cognitive disorders, memory loss, anxiety, sleep disorders, quality of life disorders, and work problems. This problem will undoubtedly impact individual productivity, so it is necessary to carry out a "Long Covid-19 Hotline". This activity aims to provide health services to Covid-19 survivors to overcome their Post-Covid conditions. The Psychologist Team of Psychology Study Program and Respiration and Pulmonology Medical Faculty Universitas Andalas conducted this activity by telephone in September and October 2021. Activities were carried out by providing psychological consultation or further recommendations for participants' psychological complaints. The results of the psychological condition of participants using Generalized Anxiety Disorder (GAD) 7 screening tools showed that the highest complaints were anxiety at 46%, insomnia at 24%, difficulty concentrating at 13%, and depression at 9% and stress at 8%. As for the follow-up results after the consultation, 90% of participants' psychological complaints were reduced, 89% of participants had made follow-up recommendations, and 100% of participants felt this activity was beneficial. Based on a survey of Covid-19 survivors, their psychological condition improved after conducting a Long Covid-19 Hotline.
The construction of emotional competency test kits for preschoolers Meria Susanti; Maria Goretti Adiyanti
INSPIRA: Indonesian Journal of Psychological Research Vol 3 No 2 (2022): Vol. 3 No. 2 December 2022
Publisher : Institut Agama Islam Negeri Langsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32505/inspira.v3i2.4975

Abstract

Emotional competence is one of the essential abilities to be possessed by children. Children with good emotional competence will be able to understand their emotions toward themselves or others well. This competence will help children adjust to and interact well in their social environment. This study aims to develop an emotional competency test kit for preschoolers. The items on this test kit are based on the theory of emotional competence presented by Denham. This test kit consists of eight-story scenarios that trigger the appearance of emotions in the child. The validity test on this test tool used expert judgment on 17 people consisting of early childhood care and education practitioners, child psychologists, parents, and Master of Professional Psychology students in Education, with the results of the analysis using Aiken’s V. Aiken’s V analysis results, obtained a validity coefficient of 0.71-0.95. Meanwhile, the results of the analysis of the test kit trial of 96 subjects obtained a reliability coefficient of emotional competency test kits of 0.801. This study showed that this test kit has good validity and reliability and can be used to measure emotional competence in preschoolers.
Kepercayaan Diri Generasi Z Indonesia Memasuki Dunia Kerja: Gambaran Self-Perceived Employability Amatul Firdausa Nasa; Meria Susanti; Lala Septiyani Sembiring; Rahmi Fahmy; Meifal Rusli; Tri Rahayuningsih; Siska Oktari; Yosea Kurnianto
Jurnal Ilmu Perilaku Vol 6 No 2 (2022): Jurnal Ilmu Perilaku
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jip.6.2.188-205.2022

Abstract

Technological advances bring transformation in employment, such as the shift of work towards digitalization. The covid-19 pandemic has also encouraged increasing technology use at work. The impact of this phenomenon is reducing the need for human resources, which increases competition in the world of work. Generation Z is a generation that currently and will face this change where they are required to have more skills so they able to compete to get and maintain their jobs.. Self-perceived employability measures individual perceptions of their ability to get and keep jobs later. This study aims to get an overview of the level of self-perceived employability in Generation Z in Indonesia by involving 1157 college students in their third and fourth years. The data was collected from 23 provinces spread across western, central, and eastern Indonesia using the online platform. The results showed that most Generation Z in Indonesia have high (67%) and moderate levels of self-perceived employability (32%). In addition, it was also found that some factors can impact increasing students' views of their employability skills. The factors are being active in organizations on campus and off campus (freelance, entrepreneurship), English proficiency (active and passive), and the Career Center in Higher Education. Keywords: World of Work, Generation Z, Indonesia, Perceived Employability
Parents Perceptions on School Readiness: Descriptive Study Meria Susanti; Izzanil Hidayati; Nila Anggreiny; Yantri Maputra
International Journal of Science and Society Vol 5 No 4 (2023): International Journal of Science and Society (IJSOC)
Publisher : GoAcademica Research & Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54783/ijsoc.v5i4.823

Abstract

The purpose of this study is to explore the parents’ perceptions on Children’s School Readiness. The open-ended question was administered to 116 parents in Padang, Padang Panjang, Bukittinggi, and Sawahlunto, West Sumatera. Content analyses were used to categorize all the response from participants. Overall this study found that 84% participants’ think that school readiness are very important for children to enter elementary school, 15% said that it’s important, and 1% quite important. Most of the reasons are because school readiness helps children to be success in elementary school. Looking more closely about their perception on school readiness, participants think that school readiness is related to cognitive ability (27%), social skill (17%), emotional competence (14%), sufficient age (11%), physical development (11%). Another response is related to financial readiness and motivation. This finding indicated that many parents considered that cognitive ability such reading skill as one of significant factor for children to enter elementary school.
Family Psychological Resistance from Batobo Cultural Perspective Yantri Maputra; Lady Diana Yusri; Meria Susanti; Qolbi Khoiri
Jurnal Psikologi Islam dan Budaya Vol 6, No 2 (2023): JPIB : Jurnal Psikologi Islam dan Budaya
Publisher : Faculty of Psychology, Sunan Gunung Djati Islamic State University of Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/jpib.v6i2.14903

Abstract

This research aims to look at the cultural values of batobo, one of the Minangkabau cultures, in building family psychological resistance. The research method used qualitative approach with a descriptive phenomenological design. Data was collected through group interviews with 2 batobo groups and in-depth interviews with 3 community leaders selected through purposive sampling techniques. Data analysis using Nvivo 10.0 software. The results show that the batobo cultural values obtained in building family psychological resistance are: (i) form good individual characteristics such as flexibility, cohesiveness, (ii) make members have a favorable view of the future, (iii) live a more meaningful life by feeling happy with what they have, and (iv) have religious beliefs. These results indicate that batobo culture can increase people's psychological resistance. These results can encourage the community to continue to maintain batobo culture so that it can become an approach to creating a society that has psychological resistance.
Evaluating factors affecting the readiness of children entering elementary school: the perspective of elementary school teachers Izzanil Hidayati; Meria Susanti; Nila Anggreiny; Yantri Maputra
Jurnal JPSD (Jurnal Pendidikan Sekolah Dasar) Vol 10, No 1 (2023): MAY
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26555/jpsd.v10i1.a26077

Abstract

Children who are ready to participate in learning at elementary school can be seen from various components, namely basic abilities, social, emotional, communication, age, and independence. This study aims to determine the problems that exist in children when entering elementary school.  This study used a quantitative method with a descriptive quantitative design. The subjects in this study are 104 elementary school teachers (84 public; 20 private). The measuring instrument in this study uses an open questionnaire containing questions about the problems encountered by elementary school teachers regarding the readiness of children to enter elementary school. The results showed that the problems encountered by primary school teachers who teach first-grade students in terms of school readiness could be divided into three categories: (1) basic abilities of children refer to a child's abilities that can support independence in learning (cognitive); (2) social abilities are defined by a child's ability to form friendships with classmates, collaborate, and play with peers; and (3) parental support associated with the presence of parents in accompanying the child's learning process and meeting the child's psychological needs and facilities. Thus, children who are ready for school are assessed from their cognitive abilities and other important aspects.
Initial Ability of Students' Science Literacy on Optical Material in Senior High School SUSANTI, MERI; Sari, Silvi Yulia
PILLAR OF PHYSICS EDUCATION Vol 16, No 3 (2023)
Publisher : Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/14930171074

Abstract

Science literacy is one of the keys to facing the development of today's era. The importance of science literacy ability makes Indonesia take part in assessments conducted by international institutions. Based on the report of the international study conducted by PISA, it shows that the science literacy of students in Indonesia is still low and still far from the average international score. The purpose of this study was to determine the initial ability of students' science literacy on the material of optical devices in senior high school. This research used a descriptive method with a quantitative approach with a sample of 31 students in senior high school. The results of this study indicate that the average value of students' science literacy in the aspects of context, competence, and knowledge aspects is still low. The results of the context aspect research on personal, local, and global indicators obtained average scores of 47.75, 18.27, and 25.68. While the competency aspect on indicators of explaining scientific phenomena, evaluating and designing research, and interpreting data and scientific evidence obtained an average value of 28.57, 32.04, and 29.08, while the knowledge aspect on content, procedural, and epistemic indicators obtained an average value of 42.67, 32, and 16.53. Thus, there is a need for learning designs that apply science knowledge in life that can improve science literacy ability and assessment instruments to evaluate related science literacy ability.
HUBUNGAN KEEFEKTIFAN PEMBERIAN ASI DENGAN DERAJAT IKTERIK BAYI HIPERBILIRUBINEMIA FISIOLOGIS DI RUANGAN PERINATOLOGI RSU BINA KASIH MEDAN Ningtiyas, Meiga Puji; Manurung, Mei Juita; Nita, Melda; Bangun, Mentari Wahyunta Br; Susanti, Meri; Nababan, Tiarnida
(Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) Vol 8, No 1 (2023):
Publisher : Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37887/jimkesmas.v8i1.32132

Abstract

AbstrakHiperbilirubinemia merupakan salah satu masalah yang serius dan sering ditemukan pada bayi baru lahir yang dapat menyebabkan kesakitan, kecatatan dan kematian pada neonatal. Hiperbilirubin pada bayi baru lahir merupakan penyakit yang disebabkan oleh penimbunan bilirubin dalam jaringan tubuh sehingga kulit, mukosa, dan sklera berubah warna menjadi kuning. Hiperbilirubinemia fisiologis tidak memerlukan penanganan yang khusus, namun dengan pemberian minum yang sering dan sedini mungkin dapat menurunkan kadar bilirubin dalam tubuh bayi baru lahir. Makanan dan minuman yang terbaik  pada bayi baru lahir ialah air susu ibu atau sering disebut dengan ASI. Dengan keefektifan pemberian ASI dapat menghindari terjadinya hiperbilirubin pada bayi baru lahir. Semakin sering frekuensi pemberian ASI maka semakin besar penurunan kadar biliirubin pada bayi yang mengalami hiperbilirubinemia. Penelitian ini bertujuan untuk mengetahui keefektifan pemberian ASI eksklusif ibu postpartum, derajat ikterik bayi hiperbilirubinemia fisiologis serta mengetahui hubungan keefektifan pemberian ASI dengan derajat ikterik bayi hiperbilirubinemia fisiologis di ruangan perinatologi RSU Bina Kasih Medan Tahun 2022. Jenis penelitian ini ialah penelitian kuantitatif menggunakan rancangan survey analitik pendekatan cross sectional. Sampel dalam penelitian ini ialah seluruh orang tua dan bayi yang mengalami hiperbilirubinemia fisiologis di RSU Bina Kasih Medan tahun 2022 sebanyak 30 sampel. Hasil uji statistic dengan iji chi square, didapatkan nilai p-value sebesar 0,000 dimana lebih kecil dari 0,05 (0,000<0,05), sehingga dapat kita artikan terdapat hubungan keefektifan pemberian ASI dengan derajat ikterik bayi hiperbilirubinemia fisiologis di Ruangan Perinatologi RSU Bina Kasih Medan Tahun 2022. Diharapkan dengan penelitian ini dapat memberikan informasi bahwa keefektifan pemberian ASI sangat penting dan bermanfaat karena selain sebagai nutrisi juga dapat mempengaruhi  derajat ikterik bayi hiperbilirubinemia fisiologis.Kata Kunci : Hiperbilirubinemia, Fisiologis, ASI, Ikterik
Co-Authors Amatul Firdausa Nasa Andar Indra Sastra Anggreiny, Nila Angraini, Atika Ledia Annisa Fitriani, Annisa Anshori, Putra Anugrah, Raffli Dwi Ar, Rosmita Ariandi, M. Satriadi Aulia, Said Reza Bangun, Mentari Wahyunta Br Br Saragih, Zanariah Busihat, Busihat Cikita Aidha Putri Dachriyanus Dania, Ira Aini Destiniar Destiniar, Destiniar Dewi Pangestuti Diny Amenike Dira Hefni Dwi Puspasari Dwisesaria Irma Lena Efrisnal, Dodi Egha Febrianingsih Erlinda Erlinda Fahmy, Rahmi Fatma Sri Wahyuni Fatsiwi Nunik Andari Fitria Rahmi Hariko, Rezki Haznaz Dhiya Ulhaq Z.N. Hildayani Ibarra, Florante Isna Mulyani Izzanil Hidayati Julianita, Diani Kurniawati kusmiarti, reni Lady Diana Yusri lala septiyani sembiring, lala septiyani Liliyana Sari Lina, Liza Fitri Mafaza Mafaza Mamnun, Hairo Manurung, Mei Juita Mardha Akhsanita Maria Goretti Adiyanti Mayang Sari Ayu Meifal Rusli Nasril, Nasril Nasution, Halimah Thania Netrawati, Netrawati Neviyarni, Neviyarni Nila Anggreiny Nila Angreiny Ningtiyas, Meiga Puji Nita, Melda Nur Ahyani Oktaria, Selly Putra, Deddy Prima Putra, Deddy Prima Qolbi Khoiri Rahma, Dinda Saufia Rangkuti, Irmayanti Rizqillah Pasaribu, Saadatur Rozi Sastra Purna Sabiruddin, Sabiruddin Salsabila, Cantika Sari, Siti Kemala Septi Mayang Sarry Shasitharan Raman Kutty Silvi Yulia Sari Siska Oktari Sufyarma Marsidin Suhatri Suhatri Surya Akbar Sylvia Dewiriza Tiarnida Nababan Tri Rahayuningsih Wahyu Widodo Wahyu, Haifa Yantri Maputra Yeni Karneli Yohannes Alen Yosea Kurnianto