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All Journal Jurnal Sain Veteriner Indonesian Journal of Tropical and Infectious Disease Jurnal Medik Veteriner Journal of Parasite Science Ovozoa: Journal of Animal Reproduction Indian Journal of Forensic Medicine & Toxicology journal of Basic Medical Veterinary Jurnal Riset Rumpun Ilmu Hewani (JURRIH) PCJN Pharmaceutical and Clinical Journal of Nusantara Jurnal Agro Veteriner
Mafruchati, Maslichah
Division Of Veterinary Anatomy, Faculty Of Veterinary Medicine, Universitas Airlangga, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Crataegus Oxyacantha Based on Bioinformatics Studies and Toxicity Test on The Chicken Embryo Maslichah Mafruchati
JURNAL RISET RUMPUN ILMU HEWANI Vol. 4 No. 2 (2025): Oktober : JURRIH: JURNAL RISET RUMPUN ILMU HEWANI
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrih.v4i2.7938

Abstract

Hawthorn extract has been used for ameliorating cardiac disorders and pulmonary hypertension. The main chemical constituents of hawthorn flavonoid extract (HFE) include flavonoids (1-2%), oligomeric proanthocyanidins (1-3%), and other bioactive components (e.g., triterpene acids, organic acids, sterols, and cardioactive amines). These compounds are reported to have many pharmacological effects, including neuroprotective, hepatoprotective, cardioprotective, and nephroprotective effects. This study was aimed the analysis Crataegus oxyacantha based on a bioinformatic study and toxicity test on the chicken embryo. This method consisted of analysis of the three-dimensional structure of Crataegus oxyacantha Protein, Epitope and Allergen Proteins, Crataegus oxyacantha Proteins that were antigens and toxins and toxicity test on the chicken embryo. The results of research conducted on 3 three-dimensional structures of Crataegus oxyacantha protein, GQME value and QmeanDisCo value. In addition, this study also obtained the results of proteins that are epitope, antigenic, non-allergenic and non-toxic and toxicity test on the chicken embryo was 250 ng/egg..Morphological description of the embryo on the 21st day after injection, at a concentration of 250 ng of Crataegus oxyacantha /egg product, an abnormal embryological picture was obtained. Chicken Embryo Weight and Body Length Measurements were carried out in chicken embryos. Need research for other species of plant.
Achillea millefolium Based on Bioinformatics Studies and Toxicity Test on The Chicken Embryo Maslichah Mafruchati
JURNAL RISET RUMPUN ILMU HEWANI Vol. 4 No. 2 (2025): Oktober : JURRIH: JURNAL RISET RUMPUN ILMU HEWANI
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrih.v4i2.7939

Abstract

In Iranian Traditional Medicine, some herbs like Achillea millefolium, commonly known as yarrow, are implicated as appetite enhancers. However, there is not enough research evidence to prove their actual effect. Achillea millefolium is a dicot which belongs to the family Asteraceae. The purpose of this study was the analysis Achillea millefolium based on a bioinformatic study and toxicity test on the chicken embryo. This research method consisted of conversion of nucleotides into amino acids, analysis of the three-dimensional structure of Achillea millefolium protein, epitope and Allergen Proteins, antigens and toxins and toxicity test on the chicken embryo. In addition, this study also obtained the results of proteins that are epitope, antigenic, non-allergenic and non-toxic and toxicity test on the chicken embryo was 250 ng/egg.. Morphological description of the embryo on the 21st day after injection, at a concentration of 250 ng of Mentha piperita/egg product, an abnormal embryological picture was obtained. Chicken Embryo Weight and Body Length Measurements were carried out in chicken embryos. Need research for other species of plant.
Effect of Moringa oleifera Lam. Leaf Extract on Sperm Motility and Abnormality in White Rats (Rattus norvegicus) Exposed to Cigarette Smoke: An In Vivo Experimental Study Bachtiar, Harris Yudhanta; Mafruchati, Maslichah; Yudaniayanti, Ira Sari; Restiadi, Tjuk Imam; Utomo, Budi; Plumeriastuti, Hani
Jurnal Sain Veteriner Vol 43, No 3 (2025): Desember
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.106028

Abstract

Background: CSE has been shown to induce oxidative stress, negatively impacting sperm quality and morphology by decreasing motility and increasing abnormalities. Moringa oleifera Lam. leaves are rich in flavonoids and other antioxidants that may counteract the harmful effects of free radicals. Objectives: This study aimed to investigate the effect of Moringa oleifera leaf extract on sperm motility and abnormality in male white rats (Rattus norvegicus) exposed to cigarette smoke. Method: This true experimental study used a completely randomized design. Twenty-five male rats were divided into five groups: negative control (K−), positive control (K+), and three treatment groups (P1, P2, P3) receiving oral administration of Moringa leaf extract at graded doses (13, 26, and 52 mg/kg BW) for 14 days, along with daily exposure to cigarette smoke. Results: Results showed that group P3 (52 mg/kg BW) had significantly higher sperm motility compared to the positive control and was statistically comparable to the negative control (p<0.05). Furthermore, sperm abnormality in group P3 decreased significantly, approaching the normal range. Conclusion: In conclusion, the administration of Moringa oleifera leaf extract at a dose of 52 mg/kg BW effectively preserved sperm motility and reduced abnormality in white rats exposed to cigarette smoke. These findings support the potential of Moringa oleifera as a phytotherapeutic agent to protect reproductive health against oxidative stress.
Co-Authors AA Sudharmawan, AA Adiana Mutamsari Witaningrum Al arif, Mohammad Anam Anugrah, Alvyan Lantang Anwar Ma'ruf Asrar, Siti Iqmallisa Nurrill Bachtiar, Harris Yudhanta Boedi Setiawan Budi Utomo Chusniati, Sri Dewi, Sapna Kurnia Eka Pramyrtha Hestianah Emy Koestanti Sabdoningrum Erma Safitri Fadhli Rahman Fauzi Gandul Atik Yuliani Ginta Riady Hana Eliyani Hani Plumeriastuti Hermin Ratnani IMAM MUSTOFA Ira Sari Yudaniayanti Ismudiono Ismudiono Iwan Sahrial Hamid Iwan Sahrial Hamid Jonathan Makuwira Kusnoto Kusnoto, Kusnoto Lestari, Dewi Sri Lokapirnasari, Widya Paramitha Lucia Tri Suwanti, Lucia Tri Luqman, Epy Muhammad Makuwira, Jonathan Meles, Dewa Ketut Mohammad Sukmanadi Mufasirin Muhammad Ilyas Wahyudi Nur, Maysarah Oktavia Praja, Ratih Novita Prastiya, Ragil Angga Rekasni Adallin A/P Morgan A/P Morgan Revina Ayu Septiani Rimayanti Rimayanti Rochmah Kurnijasanti Saputro, Amung Logam Setiawan Koesdarto Shabira, Zahra Sri Hidanah Sri Mulyati Sri Mumpuni Suherni Susilowati Tita Damayanti Lestari Tjuk Imam Restiadi Trilas Sardjito Tyasningsih, Wiwiek Viski Fitri Hendrawan Wahyudi, Nurul Tri Warsito, Sunaryo Hadi Widjiati Widjiati, Widjiati Yeni Dhamayanti