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All Journal Jurnal Sain Veteriner Indonesian Journal of Tropical and Infectious Disease Jurnal Medik Veteriner Journal of Parasite Science Ovozoa: Journal of Animal Reproduction Indian Journal of Forensic Medicine & Toxicology journal of Basic Medical Veterinary Jurnal Riset Rumpun Ilmu Hewani (JURRIH) PCJN Pharmaceutical and Clinical Journal of Nusantara Jurnal Agro Veteriner
Mafruchati, Maslichah
Division Of Veterinary Anatomy, Faculty Of Veterinary Medicine, Universitas Airlangga, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Analysis Of Medicinal Plants On Embryo Development Of Mice (Mus Musculus L.) And White Rats (Rattus Novergicus): A Systematic Review Mafruchati, Maslichah; Makuwira, Jonathan
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 1 No. 01 (2022): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (455.217 KB) | DOI: 10.58549/pcjn.v1i01.4

Abstract

White rats are often used to assess protein quality, toxicity, carcinogenic, and pesticide content of an agricultural food product. M. Musculus mice are rodents that are very easy to breed, and easy to maintain. Embryogenesis is the process of growth and development of the embryo. The purpose of this study was to analyze medicinal plants on the embryonic development of Mice (Mus musculus L) and White Rats (Rattus Novergicus). This method uses a Systematic Review approach which is based on the Preferred Guide to Reporting Items for Systematic Review and Meta-analysis (PRISMA). Total of 700 articles were obtained which then entered the elimination stage resulting in 50 articles on medicinal plants (Mus musculus L) and White Rats (Rattus Novergicus). Based on the results of the study, it can be concluded that the identification of medicinal plants that are toxic to the embryonic development of Mice (Mus musculus L.) White Rats (Rattus Novergicus).
Apis Mellifera Propolis Extract As A Stimulator Of Brain Cell Development (Study On Experimental Animals) Mafruchati, Maslichah; Makuwira, Jonathan
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 1 No. 01 (2022): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (464.011 KB) | DOI: 10.58549/pcjn.v1i01.5

Abstract

Apis mellifera could have potential as cell growth stimulator ability of the propolis. It also expected to increase the growth and proliferation of brain cells. This study aimed to analyze Apis mellifera Propolis Extract as a Stimulator of Brain Cell Development in Experimental Animals. This research is an experimental study using a completely randomized design (CRD) with 6 treatments and 4 replications. The research consisted of making Propolis Extract, Making Media (DMEM Stock Media, Washing Media, Culture and Treatment Media), Brain Cell Isolation and Culture, Observation of Culture Results (Cell Viability, Population Doubling Time, The results found that all treatments with propolis extract showed higher average viability than the control, which had average viability of 86.3%. Based on PDT (Population Doubling Time value), propolis extract has a good effect on brain cell growth, hence increasing cell proliferation. In addition, the confluent brain cells of rats given propolis extract had higher average confluency than those not given propolis extract. Propolis extract can protect neurons from damage by increasing the brain-derivatedneurotrophic factor (BDNF) gene expression in cell line neuron cultures.
Testing Honey on Chicken Embryos as Candidates for Herbal Medicine in Indonesia Mafruchati, Maslichah; Makuwira, Jonathan
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 1 No. 01 (2022): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (470.052 KB) | DOI: 10.58549/pcjn.v1i01.6

Abstract

The nutrients in honey had function as antioxidants. The aim of this study was to testing honey on chicken embryos as candidates for herbal medicine in Indonesia. This study used treatment method, consisting of 6 (six) doses of honey products. The solution volume of each treatment dose was fixed at 10 l/egg via the route to the air bag. At the age of 13 days, embryo morphology and possible abnormalities were observed in all treatments. Each two eggs are cracked. The remainder was continued by incubation in the incubator until day 21. During this time the eggs were observed and the number was recorded to find out which eggs would die and which eggs would hatch at the end of the incubation period. Newborn chicks (DOC) were weighed and observed for possible morphological abnormalities. From the results of the research conducted, it was found that the percentage of viable chicken eggs sprouted after being injected with honey (days 13-21 after inoculation) and the morphology of chicken embryos after being injected with honey. Chicken Embryo Weight and Body Length Measurements were carried out in chicken embryos. The conclusion of the study is that propolis from honey products can be used as herbal medicine.
Co-Authors AA Sudharmawan, AA Adiana Mutamsari Witaningrum Al arif, Mohammad Anam Anugrah, Alvyan Lantang Anwar Ma'ruf Asrar, Siti Iqmallisa Nurrill Bachtiar, Harris Yudhanta Boedi Setiawan Budi Utomo Chusniati, Sri Dewi, Sapna Kurnia Eka Pramyrtha Hestianah Emy Koestanti Sabdoningrum Erma Safitri Fadhli Rahman Fauzi Gandul Atik Yuliani Ginta Riady Hana Eliyani Hani Plumeriastuti Hermin Ratnani IMAM MUSTOFA Ira Sari Yudaniayanti Ismudiono Ismudiono Iwan Sahrial Hamid Iwan Sahrial Hamid Kusnoto Kusnoto, Kusnoto Lestari, Dewi Sri Lokapirnasari, Widya Paramitha Lucia Tri Suwanti, Lucia Tri Luqman, Epy Muhammad Makuwira, Jonathan Meles, Dewa Ketut Mohammad Sukmanadi Mufasirin Muhammad Ilyas Wahyudi Nur, Maysarah Oktavia Praja, Ratih Novita Prastiya, Ragil Angga Rekasni Adallin A/P Morgan A/P Morgan Revina Ayu Septiani Rimayanti Rimayanti Rochmah Kurnijasanti Saputro, Amung Logam Setiawan Koesdarto Shabira, Zahra Sri Hidanah Sri Mulyati Sri Mumpuni Suherni Susilowati Tita Damayanti Lestari Tjuk Imam Restiadi Trilas Sardjito Tyasningsih, Wiwiek Viski Fitri Hendrawan Wahyudi, Nurul Tri Warsito, Sunaryo Hadi Widjiati Widjiati, Widjiati Yeni Dhamayanti