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Journal : EnviroScienteae

PENGARUH LAMA PAJANAN LOGAM BERAT KADMIUM (Cd) TERHADAP KADAR KALSIUM (Ca) DAN KADAR FOSFAT PADA TULANG TIKUS PUTIH (Rattus novergicus) Erliyanti, Emmi; Mahreda, Emmy Sri; Triawanti, Triawanti; Suhartono, Eko
EnviroScienteae Vol 11, No 2 (2015): EnviroScienteae Volume 11 Nomor 2, Agustus 2015
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/es.v11i2.1627

Abstract

This study aimed to analyze the long exposure to Cadmium (Cd) on the levels of calcium and phosphate bone white mice. This study uses a white rat bone exposed and unexposed Cd were 24 male rats were divided into 4 groups for 0, 2, 4 and 6 weeks. After the surgery and then measured levels of calcium and phosphate bone white mice. The results showed that there were significant differences in the levels of Ca between control and treatment groups. White rat bone Ca levels decreased respectively 118,067 mg/gram of bone; 87,267 mg/gram of bone; 39,667 mg/gram of bone and 13,067 mg/gram bone at weeks 0, 2, 4 and 6. The results of statistical tests performed by Kruskal-Wallis (p=0.000; p<0.05), it is stated that long exposure to Cd can significantly reduce levels of Ca in the bones of mice. This happens due to a decrease in absorption in the intestine Cd Cd compete with, so that the levels of Ca in bones decreased. In addition the research also showed levels of phosphate bone consecutive weeks 0, 2, 4 and 6 is equal to 335,583 mg/L; 258,583 mg/L; 251,833 mg/L and 208,667 mg/L. Results of statistical tests performed by Kruskal-Wallis (p=0.116; p>0.05), which means that exposure to Cd can not lower phosphate levels significantly due to the reciprocal relationship between Ca and P which resulted in secretion of parathyroid hormone so the bone does not release phosphate in the number of great. Thus concluded that exposure to heavy metals cadmium (Cd) for 6 weeks can reduce bone calcium white mice, but have not been able to reduce levels of phosphate bone white mice significantly.
Co-Authors A.A. Ketut Agung Cahyawan W Adi Nugroho Aditya Rizky Arief Rahman Agung Ary Wibowo Airalngga, Dimas Ikhsan Al-Audhah, Nelly Alexandra, Francisca Diana Aliyah Zahirah Putri Armelin, Armelin ary yunanto Askandar Tjokroprawiro Asnawati Asnawati Athiya Nadifa Azma Rosida Bambang Setiawan Chaerany, Annisa Fitria Dewi Rahayu Dewiarianti, Dewi Didik Dwi Sanyoto Didik Dwi Sanyoto Didik Dwi Sanyoto Didik Dwi Sanyoto Dimas Ikhsan Airlangga Dimas Ikhsan Airlangga Dwi Setyohadi Dwi Setyohadi, Dwi Dwiputra Tesan Panenga, Dwiputra Tesan Eko Suhartono Emmy Sri Mahreda Erliyanti, Emmi Ermina Istiqomah, Ermina Fadhilah, Syaiful Fakhrurazzy Fakhrurazzy, Fakhrurazzy Fakhrurrazy Fakhrurrazy Faradhiba Tantri Lemba Farida Heriyani Faturrahman, Muhammad Syauqi Fitria, Yanti Frethernety, Agnes Fujianti, Annisa Gastin Gabriel Jangkang Gastin Gabriel Jangkang Ginting, Nabilla Syafirah Br. Hartoyo , Edi Hasanah, Sophia Hendra Nur&#039;amin Hendriyono, Franciscus Xaverius Herawati Herawati Hidayat Sujuti Hidayatullah Hidayatullah Husaini Husaini Hutapea, Lowisa Kristina Ida Yuliana Ika Kustiyah Oktaviyanti Indriani Adhaini Gusasi Irfan Maulana, Irfan Istiana Istiana Istiana Istiana Juhairina Juhairina Juhairina, Juhairina Lena Rosida Limantara, Sherly M Rasjad Indra M, Satriyandi Mariyatul Mariyatul, Mariyatul Ma’ruf, Muhamad Adi Meitria Syahadatina Noor Meitria Syahadatina Noor Mohammad Bakhriansyah Muhammad Agung Perdana Muhammad Azra Inan Abdillah Muhammad Reyhan Firdaus Muthmainah, Noor Muthmainah, Noor Nastiti, Titis Nathan Aditya Willyanto Nathania Hosea Nelly Al Audhah Nelly Al Audhah Nia Kania Noor , Meitria Syahadatina Novita Ningtyas, Novita Nur Qamariah Nur Qomariah Nur Qomariah Nurul Hidayah NURUL HIDAYAH Nuryandi Khairunanda, Nuryandi Olivia Dewi Rianti, Olivia Dewi Pratama, Muhammad Noor Aditya Prenggono, Muhamad Darwin Rahmadayanti, Tyas Ningrum Rakhmawati, Yuli Rini, Kusuma Hati Purnama Rizky Mutiara Lestari, Rizky Mutiara Robiana M. Noor, Robiana M. Rosadi, Muhammad Alghifari Roselina Panghiyangani Rosihan Adhani, Rosihan Sadiqi , Muhammad Abdan Sanyoto, Didik Dwi Skripsiana, Nika Sterina Suryono, Didik Dwi Syaiful Fadhilah Syamsul Arifin Taupiek Rahman, Taupiek Tika Nurullita, Tika Tyas Ningrum Rahmadayanti Ulfah, Fahrina Umi Mardiyati Vory Vory Xena Asterina Susilo Yanti Fitria Yunita Sari Yunus, Muhammad Alif