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All Journal Jurnal Fitofarmaka Indonesia As-syifaa Jurnal Farmasi Jurnal Review Pendidikan dan Pengajaran (JRPP) Pharmaceutical Sciences and Research (PSR) Jurnal Farmasi Indonesia Celebes Journal of Community Services Jurnal Sains dan Kesehatan Makassar Natural Product Journal MPSJ
Virsa Handayani
Universitas Muslim Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Social Sciences Other

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UJI TOKSISITAS EKSTRAK ETANOL BATANG KAYU WOLE WOE TERHADAP LARVA Artemia salina Leach MENGGUNAKAN METODE Brine Shrimp Lethality Test (BSLT) Virsa Handayani; Safriani Rahman; Andi Nur Alam Amaliah
As-Syifaa Jurnal Farmasi Vol 14, No 2 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i2.901

Abstract

The Wole Woe plant is one of the plants that is empirically used as traditional medicine by the Weda community in Central Halmahera Regency. The stem part of the Wole Woe plant is used to treat various diseases. This study aims to determine the toxicity of Wole Woe logs using the Brine Shrimp Lethality Test (BSLT) method. This research was started by extracting Wole Woe logs using ethanol 70% solvent with the reflux method and then carried out phytochemical screening which showed that Wole Woe logs contained alkaloids, flavonoids, saponins, triterpenoids, and tannins compounds. Toxicity testing of Wole Woe wood stem ethanol extract against Artemia salina Leach larvae was divided into 5 test groups, namely 4 treatment groups (concentrations of 250 ppm, 500 ppm, 750 ppm, and 1000 ppm) and 1 control or comparison group (sea water). Each concentration was made in 3 vials containing 10 larvae of Artemia salina Leach. Observations were made by looking at the mortality of Artemia salina Leach larvae after 24 hours of treatment. The results of the study can be seen through probit analysis by calculating the LC50 value. The LC50 of the ethanol extract of Wole Woe logs is 453.942 ± 59.564 g/mL. This indicated that the ethanolic extract of Wole Woe logs had a toxic effect on Artemia salina Leach larvae because the LC50 value was< 1000 ppm
Standarisasi Ekstrak Etanol Buah Bintaro (Cerbera odollam Gaertn.) Sebagai Obat Tradisional Rezki Amriati Syarif; Virsa Handayani; Alfirah Angraeni
Jurnal Fitofarmaka Indonesia Vol 9, No 2 (2022): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v9i2.592

Abstract

This research was conducted with the aim of examining the utilization of bintaro fruit extract (Cerbera odollam Gaertn.) as a traditional medicine that meets quality standards, so that the extract standardization process was carried out by determining specific and non-specific parameters.Based on the enormous potential of the Bintaro plant as a natural ingredient that can be used as traditional medicine, it is necessary to standardize the Bintaro fruit extract to determine the quality and safety of the extract raw materials used to support health. The research was conducted by determining the standardization of data on the determination of specific and non-specific parameters. The specific parameters that have been carried out include the identity of the extract, organoleptic test, the content of water soluble compounds 19.7%, the content of ethanol soluble compounds 6.96%, the content of positive extract compounds containing alkaloids, flavonoids, terpenoids, tannins and saponins. Non-specific parameters that have been carried out include drying shrinkage of 0.197%, moisture content of 2.124%, total ash content of 3.65%, acid soluble ash content of 1.3%, metal contamination of Pb and Cd 0.02 µg/g, microbial contamination of ALT bacteria. 0 colonies and 20 colonies of yeast. The results of the study met the standardization of extract quality.The data that will be obtained is expected to be additional information about the ethanolic extract of bintaro fruit (Cerbera odollam Gaertn.) that meets quality standards as traditional medicine, so as to maintain consistency and uniformity of efficacy and keep active compounds consistently measurable between treatments, and can maintain safety on consumers.
Ethnopharmacy Study of Herbal Medicine as Antihypertension in Simbang District Selpida Handayani; Abd. Malik; Nurul Ilmi Mufidah; Risda Waris; Virsa Handayani; Reski Amriati Syarif; Dedy Putra Wahyudi
Jurnal Fitofarmaka Indonesia Vol 9, No 3 (2022): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION)
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v9i3.914

Abstract

Empirically, the Indonesian people have used medicinal plants to cure various diseases. Ethnopharmaceutical studies were carried out as an effort to maintain knowledge of medicinal plants in the community, especially in Simbang District. This study aims to obtain data and information related to medicinal plants used as antihypertensives by the community in Simbang District, Maros Regency. This study was a survey study using a descriptive observational method where sampling uses purposive sampling techniques through interviews and questionnaire distribution. The results obtained were 17 species, 15 families and 16 genera that were used as antihypertensives. Plant parts used as antihypertensives were leaves, fruits, seeds, rhizomes and tubers. The way to use antihypertensive medicinal plants by the community in Simbang District was to be eaten and drunk by processing boiled, brewed, grated and ground.
Postprandial Bioassay and Radical Scavenging on n-Hexane Fraction of Cordia myxa L. Leaf Virsa Handayani; Aktsar Roskiana Ahmad; Nur Rezky Khairun Nisaa; La Hamidu; Ahmad Najib
Jurnal Fitofarmaka Indonesia Vol 9, No 3 (2022): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION)
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v9i3.917

Abstract

Cordia myxa L. is empirically used as an antidiabetic medication. The aim of this study is to determine the in-vivo effect of Cordia myxa L. n-hexane fraction on reducing blood sugar levels and their relationship with the anti-free-radical activity assay using DPPH (1,1-diphenyl-2-Picrylhydrazyl). The n-hexane fraction of Cordia myxa L. was used as a sample in the post-prandial assay which was analyzed using the ANOVA statistical test followed by Post-Hoc test. The results showed that there were significant in the extract using a 500 mg dose. In the anti-free-radical test using DPPH (1,1-diphenyl-2-Picrylhydrazyl) at maximum wavelength of 516 nm, 16.49 µg /mL IC50 value was obtained. For comparison, Quercetin with IC50 0.13 µg/mL was used. This shows that the sample has strong anti-free radical inhibitory potential ranged from 10 µg/mL to 50 µg/mL. The data from the calculation showed that there is a correlation between its effect of lowering high blood sugar level and anti-free radical activity
PENETAPAN KADAR FENOLIK EKSTRAK METANOL RUMPUT POLYGALA (POLYGALA PANICULATA L.) DENGAN METODE KLT-DENSITOMETRI Aktsar Roskiana ahmad; Dwiyanti Puspitasari; Virsa Handayani
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 12 No. 1 (2020): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (292.933 KB) | DOI: 10.35617/jfionline.v12i1.67

Abstract

Polygala grass (Polygala paniculata L.) is a plant that grows a lot in the Enrekang area, South Sulawesi. Polygala grass (Polygala paniculata L.) belongs to the Polygalaceae family which is widely used by the community as a medicine to treat wound. This study aims to determine the phenolic content in the methanol extract of polygala grass (Polygala paniculata L.). Methanol extract of polygala grass (Polygala paniculata L.) was obtained by maceration method with methanol P as solvent. Chemical component analysis used thin layer chromatography (TLC) method which was marked by the appearance of stains. The determination of phenolic content of methanol extract of polygala grass (Polygala paniculata L.) using the TLC-Densitometry method. The results showed that the phytochemical test on the methanol extract of polygala grass (Polygala paniculata L.) was positive for 35.280 µg of phenolic compounds.
Aktivitas Larvasida Ekstrak Daun Bintaro (Cerbera odollam Gaertn.) Terhadap Larva Nyamuk Aedes aegypti Virsa Handayani; Rezki Amriati Syarif; Aktsar Roskiana Ahmad; Andi Afifah Amdar
Jurnal Fitofarmaka Indonesia Vol 10, No 2 (2023): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v10i2.940

Abstract

Bintaro Leaf (Cerbera odollam Gaertn) contains alkaloids, flavonoids, saponins and tannins that have the potential as larvicides. The study aimed to determine the mortality rate of Aedes aegypti mosquito larvae after administration of Bintaro leaf extract as indicated by the LC50 value. The extract was obtained by maceration method. The yield of Bintaro Leaf (Cerbera odollam Gaertn)extract was 6.03%. This study used 180 mosquito larvae (Aedes aegypti) instar III, divided into test solutions made with 4 concentrations (10,000 ppm, 1000 ppm, 100 ppm and 50 ppm), positive control using Abate and negative control using Aquadest. Observations were made after 24 hours of treatment. The results of the larvacide test showed that the Bintaro leaf extract was effective as a larvicidal as indicated by the LC50 value of 21.170 g/mL 1000 g/mL.  
Analisis Kadar Total Flavonoid Ekstrak Etanol Kulit Pisang Cavendish (Musa paradisiaca var. Sapientum) Menggunakan Metode Spektrofotometri Uv-Vis: Analysis of Total Flavonoids in the Ethanol Extract of Cavendish Banana Peel (Musa paradisiaca var. Sapientum) Using the Spectrophotometry Uv-Vis Method Nur Rezky Khairun Nisaa; Abd. Malik; Virsa Handayani
Jurnal Sains dan Kesehatan Vol. 5 No. 2 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i2.1810

Abstract

Cavendish banana (Musa paradisiaca var. Sapientum) is a type of banana that is widespread in various tropical countries and is used by the community as a food source. Bananas have the ability to increase the body's ability to absorb nutrients and can help maintain the lining of cells in the intestine. This is because the content contained in bananas is short chain fatty acid compounds. According to research banana peel is rich in flavonoids. The purpose of this study was to determine the levels of total flavonoids in ethanol extract peel Cavendish Banana (Musa paradisiaca var. Sapientum). Qualitative analysis performed by the method thin layer chromatography (TLC) which is characterized by the appearance of fluoresences yellow stains in UV 366 with using AlCl3 & Sitroborat. Determination of total flavonoid content by UV-Vis spectrophotometry method using regular standard measured at a wavelength of 410 nm. The results showed that the levels of flavonoids in Cavendish banana peel that is 1,643%. Keywords: Cavendish Banana, Ethanol extract, flavonoid content Abstrak Pisang cavendish (Musa paradisiaca var. Sapientum) adalah salah satu jenis pisang yang tersebar luas di berbagai Negara tropis dan dimanfaatkan oleh masyarakat sebagai sumber pangan. Pisang memiliki kapabilitas dalam meningkatkan kemampuan tubuh dalam menyerap nutrisi dan mampu membantu memelihara lapisan sel yang berada di usus. Hal tersebut karena kandungan yang terdapat di dalam buah pisang yaitu senyawa asam lemak rantai pendek. Kulit Pisang cavendish kaya akan senyawa flavonoid. Tujuan dari penelitian ini adalah untuk menentukan kadar flavonoid total pada ekstrak etanol kulit Pisang cavendish (Musa paradisiaca var. Sapientum). Analisis kualitatif dilakukan dengan metode kromatografi lapis tipis (KLT) yang ditandai dengan adanya penampakan noda dengan fluoresensi kuning pada UV 366 menggunakan AlCl3 & noda fluoresensi kuning kehijauan pada UV 366 menggunakan Sitroborat. Penetapan kadar flavonoid totalnya dengan metode spektrofotometri UV-Vis menggunakan standar rutin yang diukur pada panjang gelombang 410 nm. Hasil penelitian menunjukan bahwa kadar flavonoid pada kulit Pisang cavendish yaitu 1,643%. Kata Kunci: Pisang cavendish, ekstrak etanol, flavonoid
Manisan MKS “Pendekatan Produksi dan Manajerial” Ahmad, Aktsar Roskiana; Murfat, Zulkifli; Handayani, Virsa
Celebes Journal of Community Services Vol. 3 No. 2 (2024): Juni - November
Publisher : STIE Amkop Makassar, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Manisan buah adalah salah satu camilan atau makanan pendamping yang banyak diminati warga makassar. Salah satu pelaku usaha pembuat manisan di makassar adalah UKM manisan MKS. Tujuan kegiatan ini adalah memberikan pendampingan produksi dan tata kelola managerial kepada UMKM sehingga produksi dan profit dapat meningkat. Metode kegiatan ini melalui beberapa pendekatan yaitu metode pelatihan metode pelatihan, metode bimbingan teknis dan pendampingan, metode pendekatan fasilitasi dan media, pendampingan produksi, pelaksanaan monitoring dan evaluasi. Dari hasil kegiatan dapat disimpulkan bahwa perlunya pendampingan produksi dan managerial pada UMKM sehingga dapat membantu peningkatan produksi, mutu dan profit.
Nugget Sosis Tuna Pencegah Stunting dan Inovatif Menaikkan Nilai Ekonomis Ikan Tuna di Desa Sanrobone Kabupaten Takalar Handayani, Virsa; Ahamd, Aktsar Roskiana; Batara, Andi Surahman
Celebes Journal of Community Services Vol. 3 No. 2 (2024): Juni - November
Publisher : STIE Amkop Makassar, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37531/celeb.v3i2.1786

Abstract

Nugget Sosis Tuna adalah produk pangan olahan yang terbuat dari daging ikan tuna yang diolah menjadi bentuk nugget atau sosis. Produk ini dirancang untuk menjadi sumber protein yang bergizi dan mudah dikonsumsi, terutama bagi anak-anak. Ikan tuna, yang kaya akan protein dan omega-3, memiliki potensi besar untuk dijadikan bahan baku dalam pembuatan makanan bergizi yang tidak hanya lezat tetapi juga mampu memenuhi kebutuhan gizi anak-anak. Nugget Sosis Tuna tidak hanya berfungsi sebagai pencegah stunting, tetapi juga berperan dalam meningkatkan nilai ekonomis ikan tuna di daerah tersebut. Dengan memanfaatkan sumber daya lokal, produk ini diharapkan dapat memberikan manfaat ekonomi bagi masyarakat setempat, meningkatkan pendapatan para nelayan, dan memperkuat ketahanan pangan. Melalui pendekatan inovatif ini, diharapkan Desa Sanrobone dapat mengurangi angka stunting sambil mendorong perkembangan ekonomi lokal yang berkelanjutan. Pengabdian ini, akan mengkaji potensi Nugget Sosis Tuna sebagai solusi gizi, serta dampaknya terhadap perekonomian masyarakat desa, yang pada akhirnya akan memberikan kontribusi positif bagi kualitas hidup dan kesejahteraan masyarakat Desa Sanrobone.
Uji Toksisitas Ekstrak Kulit Buah Tanaman Jeruk Purut (Citrus hystrix DC.) Dengan Menggunakan Metode Brine Shrimp Lethality Test (BSLT) Isti Aprilyanie; Virsa Handayani; Rezki Amriati Syarif
Makassar Natural Product Journal (MNPJ) April 2023
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Kaffir lime peel extract (Citrus hystrix DC.) contains flavonoids and alkaloids still rarely used as medicine; however, its toxicity is lack of the research until now. The research aimed to determine the effects of toxicity in the extracts by Brine Shrimp Lethality test (BSLT). The extraction used maceration and infusion. The former used ethanol of 70% with the thick extract of 3.81 mg and the letter used aquadest with the dried extract of 2.77 mg. The screening-was conducted by observing the color change in the extract and obtained the toxicity effects at the concentration of 1 ppm, 3 ppm, 5 ppm, 7 ppm, and 9 ppm by obtaining LC50 values for both the ethanol extract of 0.98 ppm and water extract of 1.20 ppm. The results showed that the water and ethanol extracts of kaffir lime peel had toxic properties.
Co-Authors -, Auliawati A Amaliah Dahlia Abd. Malik Abd. Malik Abd. Malik ABD. MALIK Abdul Rasyid, Faradiba Abdullah Mahmud Ahamd, Aktsar Roskiana Ahmad Najib Ahmad, Akstar Roskiana Ahmad, Aktsar Roskiana Alfirah Angraeni AMINAH Andi Afifah Amdar Andi Amaliah Dahlia Andi Fenny Nurvadillah Andi Nur Alam Amaliah Anisa, Rianti Asfar, Akbar Asni Amin Asriani Suhaenah Dedy Putra Wahyudi Dwiyanti Puspitasari Fadliyah, Nurfadhilah Fauzan, Muh. Alif Noor Ganoko, Marwan Ahmad Gazali, Anggun Hamidu, La Hamsinah Harti Widiastuti Hasnaeni hasnaeni, Hasnaeni HM, Nur Rahmah Isti Aprilyanie Kamase, Jeni Miswati Sudir, Miswati Murfat, Moh Zulkifli Murfat, Zulkifli Nadya, Alifah Rifa Nur Rezky Khairun Nisaa Nurfadillah Nurfadillah Nurlinda Nurlinda Nurul Hasanah Nurul Ilmi Mufidah PRAHAYU, ADE CAHYA Putri, Andra Audina Rais Razak, Rais Reski Amriati Syarif Rezki Amriati Syarif Rezki Amriati Syarif Rezki Amriati Syarif Risda Waris Risda Waris Risda Waris, Risda Safriani Rahman Safriani Rahman, Safriani Selpida Handayani Selpida Handayani, Selpida Sudarman Suriyanti Tadjuddin Naid Tonang, Maswa Ruslan Umasangaji, Ria Fitriani Zainal Abidin