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<![CDATA[PENGARUH PERUBAHAN HIPERPLASIA SEL GOBLET SELAMA 28 HARI PAPARAN ASAP ROKOK DENGAN PEMBERIAN ANTIOKSIDAN SUPEROXIDE DISMUTASE ]]>
<![CDATA[Rivan Virlando Suryadinata]]>;
<![CDATA[Bambang Wirjatmadi]]>;
<![CDATA[Merryana Adriani]]>
<![CDATA[ The Indonesian Journal of Public Health Vol. 11 No. 1 (2016): The Indonesian Journal Of Public Health ]]>
Publisher : <![CDATA[Universitas Airlangga ]]>
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DOI: 10.20473/ijph.v11i1.2016.60-68
<![CDATA[The number of Indonesian smokers in 2013 has reached 36.3% and continues to increase each year. This will directly affect the increase in passive smokers in Indonesia. Harmful free radicals from cigarette smoke inhaled can lead to irritation of the bronchial airways. Irritation of the airways characterized by mucus hypersecretion induced goblet cell hyperplasia of the bronchi. Giving antioxidants superoxide dismutase melon extract with a combination of gliadin (SOD-gliadin) reduces radical that goblet cell hyperplasia in the bronchial airways can be reduced. This study aims to determine the effectiveness of the SOD-gliadin to the decrease of goblet cell hyperplasia of the bronchi. Giving SOD-gliadin carried out for 28 days with exposure to smoke two cigarettes per day using 5 groups: negative control, positive control and 3 treatment groups with different doses (2,25 IU; 4,5 IU; 9 IU). Observation of goblet cell hyperplasia performed on histological preparations with a longitudinal section with four visual field. With the effects of the antioxidant superoxide dismutase melon extract on percentage of goblet cell hyperplasia (ANOVA, p = 0396). It can be concluded supplementation with SOD-gliadin not influence the percentage of goblet cell hyperplasia.Keywords: goblet cell, superoxide dismutase, antioxidants, cigarette, free radical]]>
<![CDATA[EFEK EKSTRAK MELON (Cucumis melo) dan GliadinTERHADAP KADAR Hb DAN HbCO TIKUS WISTAR JANTAN YANG DIPAPAR ASAP ROKOK ]]>
<![CDATA[Yuyun Erlina Susanti]]>;
<![CDATA[Bambang Wirjatmadi]]>
<![CDATA[ The Indonesian Journal of Public Health Vol. 11 No. 1 (2016): The Indonesian Journal Of Public Health ]]>
Publisher : <![CDATA[Universitas Airlangga ]]>
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DOI: 10.20473/ijph.v11i1.2016.78-88
<![CDATA[The exposure of cigarette smoke produce CO bond in hemoglobin. Melon (Cucumis melo) and gliadin contains of antioxidants that prevent tissue damage. The aim of this study was to analyze the difference of hemoglobin and carboxyhemoglobin concentration in male Wistar rats were exposed to cigarette smoke and had been treated melon extract (Cucumis melo) and gliadin. The study was a laboratory experimental design, using Post Test Control Group Design Research and RAL method (Complete Randomize Design). The sample in this study were 25 male Wistar rats aged 3 months. The research was divided into 5 groups with 5 different treatment : control group, the treatment group were given exposure to cigarette smoke, the treatment group were given of cigarette smoke exposure and melon extract (Cucumis melo) and gliadin dose of 3 IU / day, 4.5 IU / day, and 9 IU / day.The subject were divided into 5 groups each treated for 28 day. The sample size used Federer formula. The collection of data was obtained from the results of laboratory tests to hemoglobin and Carboxyhemoglobin. Hb and HbCO data collected and analyzed by Manova test at 95% confidence level. The results showed significant difference in average Hb and HbCO concentration (p-value = 0.000) between male Wistar rats treated and not treated with melon extract (Cucumis melo) and gliadin. Melon extract has an effect on the decline of HbCO concentration due to exposure to cigarette smoke.Keywords:smoke, melon extract, Hb, HbCO]]>
<![CDATA[THE RELATIONSHIP OF KNOWLEDGE, EXPOSURE TO SUNLIGHT, AND CALCIUM INTAKE WITH THE RISK OF OSTEOPOROSIS ]]>
<![CDATA[Erliza Anggraini Firdaus]]>;
<![CDATA[Bambang Wirjatmadi]]>
<![CDATA[ The Indonesian Journal of Public Health Vol. 15 No. 3 (2020): THE INDONESIAN JOURNAL OF PUBLIC HEALTH ]]>
Publisher : <![CDATA[Universitas Airlangga ]]>
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DOI: 10.20473/ijph.v15i3.2020.252-257
<![CDATA[Osteoporosis is a bone disease causing decreased bone density. It often occurs to elderly women. At the age of 50-80 years, 23% Indonesian women were at risk of osteoporosis, and this number would increase to 53% at the age of 70-80 years. This study aimed to identify the relationship of knowledge, calcium intake and exposure to sunlight habits with the risk of osteoporosis. This study used a cross-sectional design involed 26 members of the osteoporosis gymnastic group who had a low and high risk of osteoporosis. Data of food consumption were retrieved from 24-hour food recall. The chi-square analysis shows knowledge level had a relationship with risk of osteoporosis (p=0.047). Exposure to sunlight (p=0.437) and calcium intake (p = 0.187) had a relationship with the risk of osteoporosis. It can be concluded that the level of knowledge had a significant relationship with risk of osteoporosis. Knowledge variable is important to show the community mindset about the dangers and risks of osteoporosis. Therefore, education about osteoporosis is required. Keywords: osteoporosis, knowledge, calcium intake, exposure to sunlight habits.]]>
<![CDATA[Hubungan antara Kecukupan Energi dan Status Gizi dengan Produktivitas Kerja (PT. Timur Megah Steel Gresik Tahun 2019) ]]>
<![CDATA[Himaya Himaya]]>;
<![CDATA[R. Bambang Wirjatmadi]]>
<![CDATA[ Amerta Nutrition Vol. 3 No. 4 (2019): AMERTA NUTRITION ]]>
Publisher : <![CDATA[Universitas Airlangga, Kampus C, Mulyorejo, Surabaya-60115, East Java, Indonesia ]]>
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DOI: 10.20473/amnt.v3i4.2019.269-275
<![CDATA[Background: Laborers have a central role in achieving company goals that cannot be separated from their work productivity factors. Several factors that can improve work productivity in terms of nutrition are energy sufficiency and nutritional status. The difference of energy adequacy and nutritional status of each labor caused differences in works productivity.Objectives: This study aims to analyze the relation between energy adequacy and nutritional status with the productivity of labors in the packing section (setting nuts and bolts) in PT. Timur Megah Steel Gresik. Methods: This study was an observational study with a case-control research design. The sample size used in this study was 38 workers. The sample consisted of case samples and case-control. There are 19 workers with low productivity in the case sample and 19 workers with high productivity in the control sample. Data were analyzed using Spearman correlation.Results: The results of the analysis test showed that there was a relationship between energy adequacy (p<0,001) and nutritional status based on anthropometry (p<0,001) with work productivity, but there was no correlation between nutritional status based on biochemical/hemoglobin level status (p=0.172) with work productivity.Conclusions: There was a significant correlation between energy adequacy and nutritional status by anthropometry with work productivity.ABSTRAKLatar Belakang: Tenaga kerja mempunyai peranan sentral dalam mencapai tujuan perusahaan yang tidak dapat terlepas dari faktor produktivitas kerjanya. Kecukupan energi dan status gizi tenaga kerja yang masing-masing berbeda mengakibatkan adanya perbedaan produktivitas kerja yang dimiliki.Tujuan: Menganalisis hubungan antara kecukupan energi dan status gizi dengan produktivitas pada tenaga kerja laki-laki bagian packing (setting mur dan baut) PT. Timur Megah Steel Gresik.Metode: Penelitian ini merupakan penelitian observasional dengan design penelitian case control. Besar sampel yang digunakan dalam penelitian ini adalah 38 tenaga kerja. Sampel terdiri dari sampel kasus yaitu 19 tenaga kerja dengan produktivitas kurang/rendah dan sampel kontrol yaitu 19 tenaga kerja dengan produktivitas baik/tinggi. Analisis data menggunakan uji korelasi spearman.Hasil: Terdapat hubungan kecukupan energi (p=0,000) dan status gizi berdasarkan antropometri (p=0,000) dengan produktivitas kerja, namun tidak terdapat hubungan status gizi berdasarkan biokimia/status kadar hemoglobin (p=0,172) dengan produktivitas kerja.Kesimpulan: Kecukupan energi dan status gizi (antropometri) yang meningkat dapat meningkatkan produktivitas kerja.]]>
<![CDATA[Perbedaan Besaran Uang Saku Dan Aktivitas Fisik Antara Siswi Gemuk Dan Normal Di SMA Negeri 5 Surabaya ]]>
<![CDATA[Annisa Rizka Oktavianita]]>;
<![CDATA[Bambang Wirjatmadi]]>
<![CDATA[ Amerta Nutrition Vol. 4 No. 3 (2020): AMERTA NUTRITION ]]>
Publisher : <![CDATA[Universitas Airlangga, Kampus C, Mulyorejo, Surabaya-60115, East Java, Indonesia ]]>
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DOI: 10.20473/amnt.v4i3.2020.178-184
<![CDATA[ABSTRACT Background: High food consumption due to spending excess money and low physical activity could increased the risk of overweight.Objectives: This study aimed to analyzed the differences amount of pocket money and physical activity between students with overweight and normal at SMA Negeri 5 Surabaya.Methods: The design of the study was case control involving 52 samples with 26 case sampels for overweight students and 26 control sampels for normal students. Body weight measurements using a digital body scale and height using microtoise, this measurements was done before the research began. The quetioners were to identified data identity, amount of pocket money and physical activity. Data were analyzed using Mann Whitney with p>0.005.Results: Some characteristic of the sampels were based on age groups, parent’s occupation and body mass index. The average age of case sampels was 15 years old and control sampels was 16 years old. The occupation of sampels father from two groups were as employees (53.8% and 57.7%) and entrepreneurs (15.4% and 19.2%). Furthermore the occupation of sampel’s mother from two groups were as house wife (96.2% and 92.3%) and entrepreneurs (3.8%). The test result showed the p value about difference of amount of pocket money was p=0.380 and p<0.001 for physical activity.Conclusions: In conclusion there were no differences of amount of pocket money between the two groups. There were differences about physical activity between the two groups . ABSTRAKLatar Belakang: Tingginya konsumsi makanan akibat pengeluaran uang saku berlebih dan rendahnya aktivitas fisik dapat meningkatkan resiko kegemukan.Tujuan: Untuk menganalisis perbedaan besaran uang saku dan aktivitas fisik antara siswi gemuk dan normal di SMA Negeri 5 Surabaya.Metode: Penelitian ini menggunakan desain studi case control dengan total responden 52 siswi yang terbagi menjadi dua kelompok yaitu 26 siswi kelompok kasus yaitu siswi gemuk dan 26 siswi kelompok kontrol yaitu siswi normal. Dilakukan pengukuran berat badan menggunakan digital scale dan tinggi badan menggunakan microtoise untuk menilai status gizi, pengukuran ini dilakukan pada saat sebelum penelitian dimulai. Wawancara dan pengisian kuesioner guna mengetahui karakteristik dan besaran uang saku beserta aktivitas fisik responden yang diukur bersamaan pada saat pengambilan data. Teknik analisis data menggunakan uji beda Mann Whitney dengan p<0,05.Hasil: Rata-rata usia siswi pada kelompok kasus adalah 15 tahun sedangkan pada kelompok kontrol adalah 16 tahun. Pekerjaan ayah dari kedua kelompok siswi adalah sebagai karyawan swasta (53,8% dan 57,7%) dan wiraswasta (15,4% dan 19,2%). Untuk pekerjaan ibu dari kedua kelompok siswi tersebut ialah ibu rumah tangga (96,2% dan 92,3%) dan wirausaha masing-masing kelompok sebesar 3,8%. Hasil uji beda besaran uang saku adalah p = 0,380 dan hasil dari uji beda aktifitas fisik adalah p < 0,001.Kesimpulan: Tidak terdapat perbedaan besaran uang dan terdapat perbedaan aktivitas fisik antara kelompok kasus dan kontrol. Perlu diadakannya aktivitas fisik tambahan sebagai bentuk pencegahan masalah gizi lainnya. ]]>
<![CDATA[Perbedaan Kecukupan Energi dan Status Gizi Siswa Membawa Bekal dan Tidak Membawa Bekal Ke Sekolah ]]>
<![CDATA[Cindy Claudia Nurulita]]>;
<![CDATA[Bambang Wirjatmadi]]>
<![CDATA[ Amerta Nutrition Vol. 3 No. 4 (2019): AMERTA NUTRITION ]]>
Publisher : <![CDATA[Universitas Airlangga, Kampus C, Mulyorejo, Surabaya-60115, East Java, Indonesia ]]>
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DOI: 10.20473/amnt.v3i4.2019.305-309
<![CDATA[Background: The school age is growth and development era towards adolescence, and if nutritional disorders occur during this period, it will have a major impact on the next life cycle. One of the direct causes the occurrence of nutritional problems is unbalanced meal intake. Since the intake of foods that contain nutrients balanced is essential for growth and development, especially in childhood. One of the messages of a balanced nutritional guidelines for elementary school children that is bringing meal.Objectives: to study the difference of adequacy energy level and nutritional status of students who packed meal from home and not packed meal to schoolMethods: this research was an observational analytical with case control design which was located in Pacarkeling 1 Elementary School Surabaya on March – April 2019. The sample was 34 students in grade 4 and 5, also to the number of each group of 17 students. Sampling method using simple random sampling. The research Variables are adequacy difference of energy, nutritional status, students who bring meal in school. Data was analyzed by independent sample t-test. Data was collected through interview using food recall 2x24 hours, anthropometry data using weight and high measurement. Results: This study showed that there was difference of adequacy energy (p=0.011) and nutritional status (p=0.014) of students who packed meal to school and those who do not bring packed meal to school Conclusions: There was a significance difference between energy needs level and nutritional status of students who packed meal to school and those who do not bring packed meal to school ABSTRAK Latar Belakang: Masa usia sekolah ialah masa tumbuh kembang anak menuju masa remaja sehingga rentan terkena gangguan gizi. Masa usia sekolah memiliki dampak yang cukup besar untuk masa kehidupan selanjutnya. Penyebab utama adanya gangguan gizi ialah konsumsi makanan yang tidak seimbang. Konsumsi makanan yang cukup mengandung zat gizi seimbang yang sangat penting untuk tumbuh kembang anak. Berdasarkan pedoman dari gizi seimbang untuk anak sekolah dasar yaitu membawa bekal makanan ke sekolahTujuan: mempelajari perbedaan kecukupan energi dan status gizi antara siswa membawa bekal dan tidak membawa bekal ke sekolahMetode: Metode penelitian bersifat observasional analitik dengan design case control yang berlokasi di SDN Pacar keling 1 Surabaya pada Maret-April 2019. Total sampel penelitian adalah sebanyak 34 sampel dengan jumlah setiap kelompok sebesar 17 sampel. Pengambilan sampel menggunakan simple random sampling, Variabel penelitian ini yaitu kecukupan energi, siswa membawa bekal dan tidak membawa bekal dan status gizi. Data dianalisis dengan uji independent T-test. pengukuran asupan makanan menggunakan metode wawancara menggunakan recall 2x24 jam dan instrument yang digunakan adalah meliputi timbangan berat badan digital, microtoise dan kuesionerHasil: terdapat perbedaan kecukupan energi (p= 0,014) dan status gizi (p= 0,011) siswa membawa bekal dan tidak membawa bekal.Kesimpulan: Kesimpulan penelitian ini adanya perbedaan yang signifikan pada tingkat kecukupan energi, dan status gizi siswa membawa bekal dan tidak membawa bekal. sebaiknya, anak sekolah terutama sekolah dasar memperhatikan pemilihan jenis makanan sesuai dengan kebutuhan zat gizi dalam sehari. ]]>
<![CDATA[Bone Density Status and Vitamin D and Calcium Concentrations in Pregnant and Non-Pregnant Women ]]>
<![CDATA[Setiarsih, Dini]]>;
<![CDATA[Wirjatmadi, Bambang]]>;
<![CDATA[Adriani, Merryana]]>
<![CDATA[ Makara Journal of Health Research Vol. 20, No. 3 ]]>
Publisher : <![CDATA[UI Scholars Hub ]]>
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<![CDATA[Background: The aim of this study was to analyse differences in bone density and vitamin D and calcium concentrations between pregnant and non-pregnant women. Methods: This was an analytical, cross-sectional study of women aged 30 years or over, residing in the Puskesmas Bangkalan district. The sample population was chosen at random and included 10 pregnant women in their third trimester and 10 non-pregnant women. This observational study consisted of an interview, a blood test, and a 24-hour recall. The concentration of serum vitamin D (25(OH)D) was measured by Gas Chromatography and a Photometric Test measured the concentration of serum calcium. Participant's bone density was measured by bone ultra sonometer. The data was analysed using the Mann-Whitney test and assessed ultraviolet-B exposure, bone density values, and consumption of vitamin D, calcium, energy, and protein. The Student t-test was used to analyse serum vitamin D and calcium concentrations. Results: There were no differences between the groups' serum vitamin D concentrations (p = 0.946). However, there were significant differences between the groups' serum calcium concentrations (p = 0.047) and bone density values (p = 0.019). Conclusions: A high prevalence of vitamin D deficiency (25(OH)D < 50 nmol/L) and insufficiency (25(OH)D < 80 nmol/L) was observed in both groups. The mean serum calcium concentrations and bone density values were lower in pregnant subjects than non-pregnant subjects.]]>
<![CDATA[EFIKASI ANTIOKSIDAN AKAR TERUNG PIPIT (Solanum torvum) TERHADAP KERUSAKAN HATI DENGAN INDUKSI CCL4 PADA Rattus norvegicus: Efikasi Antioksidan Akar Terung Pipit (Solanum torvum) terhadap Kerusakan Hati dengan Induksi CCL4 pada Rattus norvegicus ]]>
<![CDATA[Rivan Virlando Suryadinata]]>;
<![CDATA[Dwi Martha Nur Aditya]]>;
<![CDATA[Ryu Okiku Christina Gunawan]]>;
<![CDATA[Mudita Lestari Utami]]>;
<![CDATA[Bambang Wirjatmadi]]>
<![CDATA[ Amerta Nutrition Vol. 6 No. 1SP (2022): AMERTA NUTRITION SUPPLEMENTARY EDITION Special 2nd Amerta Nutrition Conferenc ]]>
Publisher : <![CDATA[Universitas Airlangga ]]>
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DOI: 10.20473/amnt.v6i1SP.2022.59-63
<![CDATA[Background: Liver disease is still a health problem in the world. In Indonesia, liver disease is dominated by liver cirrhosis. One of the causes of liver damage is an increase in the number of free radicals in the body. This will result in damage and death of liver cells and cause fibrotic tissue. A decrease in the number of liver cells will result in impaired overall liver function. Giving antioxidants can reduce free radicals that enter the body. One of the plants that contain antioxidants is the terung pipit (Solanum torvum). Objectives: This study aims to determine the antioxidant efficacy of terung pipit root (Solanum torvum) against liver damage by CCL4 induction in Rattus norvegicus. Methods: This research is experimental using a Randomized Controlled Trial (RCT) design. The research process was carried out for 11 days by dividing the experimental animals into 6 groups with 5 individuals in each group. Each treatment group will be induced with CCL4 for 5 days and followed by 7 days of administration of terung pipit root (Solanum torvum) with different doses (0.5; 1.0; 1.5 mg/grBB/day). The parameters used are the levels of SGOT-SGPT and bilirubin in the blood. Results: The results showed a decrease in the levels of SGOT-SGPT and bilirubin in the blood in the group given the terung pipit root (p≤0,05). Increasing the dose of terung pipit root administration further decreased the research parameters, although it did not reach the value of the negative control group. Conclusions: The antioxidant content in terung pipit root (Solanum torvum) can decrease in SGOT-SGPT and bilirubin levels in the blood due to liver damage in experimental animals induced by CCL4.]]>
<![CDATA[The Expression Change of Mmp-8 and Collagen Type-2 Intracell in Lung Tissue Due to Electronic Smoke Exposure ]]>
<![CDATA[Suryadinata, Rivan Virlando]]>;
<![CDATA[Wirjatmadi, Bambang]]>;
<![CDATA[Andriani, Merryana]]>;
<![CDATA[Sumarmi, Sri]]>
<![CDATA[ KEMAS: Jurnal Kesehatan Masyarakat Vol 18, No 1 (2022) ]]>
Publisher : <![CDATA[Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang ]]>
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DOI: 10.15294/kemas.v17i2.26557
<![CDATA[The number of electronic smokers has increased annually. Exposure to an electronic cigarette will increase free radicals in the body and result in oxidative stress causing lung tissue damage. The severity degree of lung tissue damage caused by electronic smoke exposure depends on the duration of electronic cigarette smoke exposure, and will affect Matrix Metalloproteinase-8 and collagen type-2 in the cells. The study aims to understand the change degree of Matrix Metalloproteinase-8 and collagen type-2in lung tissue due to electronic cigarette smoke exposure. This study applied the experimental method with a post control group design. The male Wistar rats were used as the animal models in this research to assess cell damage through the Matrix Metalloproteinase-8 expression and collagen type-2 in the lung tissue using immunohistochemical staining. Exposure to electronic smoke cigarettes was given to each group of animal models with the difference in amount and time duration. The expression of Matrix Metalloproteinase-8 indicated a significant increase due to electronic smoke exposure (ANOVA, p=0.000). Meanwhile the expression of collagen type-2 showed a significant decrease because of electronic smoke exposure (ANOVA, p=0.000). Besides, MMP-8 and collagen type-2 manifested relationship existence and strong impact (r=0.948, p=0.000). The negative impact of exposure to electric cigarette smoke causes increased expression of Matrix Metalloproteinase-8 and decreased expression of type-2 collagen in lung tissue.]]>
<![CDATA[The role of zinc sulphate and omega 3 in improving of albumin level on pulmonary tuberculosis patients in Paru Hospital Surabaya 2015 ]]>
<![CDATA[Fara Disa Durry]]>;
<![CDATA[Bambang Wirjatmadi]]>
<![CDATA[ Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 4, No 1 (2015): edisi September 2015 ]]>
Publisher : <![CDATA[Universitas Wijaya Kusuma Surabaya ]]>
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DOI: 10.30742/jikw.v4i1.16
<![CDATA[The epidemiology of Tuberculosis (TB) showed that TB is a disease which is associated with malnutrition. Malnutrition and lacking of certain essential nutrients required by immune system might cause immune function deficiency resulting higher susceptibility to bacterial and viral infections. There is positive correlation between immune system and high nutrient contents, such as Vitamin C, zinc, and antioxidants that brings good effect on infections, including Tuberculosis. One of the efforts conducted to help promoting improving albumin level on pulmonary tuberculosis patients is through zinc and sulphate provision followed by Omega-3 supplementation. This study was conducted in 2015 aimed to analyze the role of Zinc Sulphate Omega-3 provision in improving albumin level on pulmonary tuberculosis patients in Paru Hospital, Surabaya.This study applied randomized study design using Pre-test and Post-test Control group design on patients suffering pulmonary tuberculosis. This study was conducted by administering Zinc Sulphate and Omega-3 on treatment group and placebo on the control group. The samples of this study consisted of 20 pulmonary tuberculosis patients divided into two groups: treatment group and control group. Each group consisted of 10 patients. Statistical analysis was conducted using paired T-test and independent t-test. The results is There were significant differences in albumin level (p = 0.001) in the treatment group before and after supplementation Zinc Sulphate And Omega 3. While in the control group between before and after supplementation Zinc Sulphate And Omega 3 showed no significant differences in body weight (p = 0.224). The conclusions is Zinc Sulphate and Omega 3 plays a role in increasing albumin level respondents. There are significant differences on albumin level before and after supplementation Zinc Sulphate And Omega 3.]]>
