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All Journal Indonesian Journal of Urology Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education Berkala Kedokteran Majalah Obstetri dan Ginekologi Sari Pediatri Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Journal of Maternal and Child Health Jurnal Ilmu Kedokteran dan Kesehatan JURNAL ETIKA KEDOKTERAN INDONESIA eJournal Kedokteran Indonesia Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)

Budi Wiweko

Departemen Obstetri Dan Ginekologi, Fakultas Kedokteran, Universitas Indonesia

Author-ID : 419518

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Published : 38 Documents Claim Missing Document

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Articles

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The Outcome on Conservative Surgical Treatment of Adenomyosis Wiweko, Budi; Legiantuko, Ario; Kemal, Achmad; Pratama, Gita; Situmorang, Herbert; Sumapraja, Kanadi; Natadisastra, Muharam; Hestiantoro, Andon
Indonesian Journal of Obstetrics and Gynecology Volume 4, No. 4, October 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To understand the outcome on conservative surgical treatment of adenomyosis. Methods: A retrospective cohort study followed for 2 years from 2010 to 2012 of women with adenomyosis were diagnosed by transvaginal sonography and confirmed histologically. Subjects divided into women who were treated by adenomyosis resection (with/without Osada’s technique) and who were underwent hysterectomy. Results: After the surgery, as many as 40 patients (81.63%) did not feel any pain (VAS 0), and 9 patients (18.37%) still felt pain. For the fertility outcome, we had 8 patients (20.51%) getting pregnant naturally without any fertility intervention. Two patients (5.13%) had successfully conceived by IVF. According to the type of surgery, from 8 natural pregnancy, 7 patients (87.50%) was underwent conventional resection of adenomyosis and 1 patients (12.50%) underwent Osada’s procedures. Two patients who were conceived by IVF, both of them were underwent Osada’s resection. Conclusion: Adenomyosis resection both conservative or Osada’s procedures actually has a better outcome for relieving pain; therefore, some patients can still have a child. Keywords: adenomyosis resection, conventional resection, infertility, Osada’s procedure

Anti Müllerian Hormone as a Predictor of Metabolic Syndrome in Polycystic Ovary Syndrome Wiweko, Budi; Susanto, Cynthia A.
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 2, April 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To evaluate whether Anti Müllerian Hormone (AMH) can be used as a predictor of metabolic syndrome in Polycystic Ovarian Syndrome (PCOS).Methods: This cross-sectional study was conducted in Yasmin Clinic, Dr. Cipto Mangunkusumo General Hospital Jakarta between June and December 2012. Forty-one patients diagnosed with PCOSbased on Rotterdam Criteria were enrolled. Secondary were was taken from medical record..Results: A total of 22 subjects were involved in this study. Mean AMH level in the metabolic syndrome group is compared to the non-metabolic syndrome group (10.72 ± 6.23 ng/ml vs 7.97 ± 4.50ng/ml, p=0.12). AMH was strongly associated with HDL, triglyceride and insulin resistance (r-value of -0.29, 0.23, and 0.21 respectively, p < 0.05).Conclusion: AMH can be used as a predictor of metabolic syndrome in PCOS.[Indones J Obstet Gynecol 2017; 5-2: 83-86]Keywords: anti müllerian hormone, metabolic syndrome, polycystic ovarian syndrome

EFFICACY OF SURGICAL SPERM RETRIEVAL IN AZOOSPERMIC PATIENT AND ITS CONTRIBUTION TO IN VITRO RERTILIZATION PROGRAM Gde Sanjaya, I Putu; Birowo, Ponco; Rasyid, Nur; Sini, Ivan Rizal; Wiweko, Budi
Indonesian Journal of Urology Vol 22 No 2 (2015)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v22i2.186

Objective: This study was made to evaluate efficacy and success rate of Percutaneous Epididymal Sperm Aspiration (PESA), Microsurgical Epididymal Sperm Aspiration (MESA), or Testicular Sperm Extraction (TESE) in azoopsermic patients, and evaluate IVF program’s pregnancy rate by comparing methods of sperm retrieval. Material & method: A descriptive retrospective study to azoospermic patients undergone PESA, MESA or TESE and IVF program in Bunda Hospital Jakarta and Cipto Mangunkusumo Hospital Jakarta in 2011–2012. The data were collected from patients’ medical records and IVF program’s database. Results: There were 146 azoospermic patients with mean age 38.97 ± 7.35 years. Viable sperm was found in 46 patients (31.5%) by PESA and 47 patients (32.2%) by MESA and TESE. The IVF program was followed by 72 patients. Sperm was retrieved by PESA in 43 patients (59.7%) and TESE in 29 patients (40.3%). Pregnancy was achieved in 18 patients in PESA group (25%) and 15 patients (20.8%) in TESE group. Conclusion: Sperm can be retrieved from azoospermic patients by PESA, MESA or TESE, and there was good success rate in pregnancy rate of IVF program by using surgically retrieved sperm.

Premature Rupture of Membrane Outcome Determinants in Reproductive Age Women Zakirah, Sarah Chairani; Eyanoer, Putri Chairani; Azali, Chairul Nurdin; Wiweko, Budi
Journal of Maternal and Child Health Vol. 5 No. 4 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (34.211 KB)

Background:

Differences in Age and Body Mass Index of Women with Polycystic Ovary Syndrome Attending in Vitro Fertilization (IVF) Program Roselina Panghiyangani; Husnul Khatimah; Dwi Anita Suryandari; Budi Wiweko; Mala Kurniati
Berkala Kedokteran Vol 15, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Nutritional status in this case BMI in women is very important in relation to infertility problems in women of reproductive age. Polycystic ovary syndrome (PCOS), is a reproductive problem with hormonal disorders. Infertility Female with PCOS is associated with anovulation, high LH and hyperandrogenism. The purpose of this study was to analyze differences in age and body mass index (BMI) of PCOS women undergoing in vitro fertilization (IVF). This was an observational analytic study. The subjects of the study were women aged 30-40 years who undergoing IVF-assisted fertilization program at Yasmin Clinic - RSCM Kencana who was diagnosed as PCOS. As a comparison are women 30-40 years who have infertility problems but not PCOS who underwent IVF-assisted fertilization program. Women diagnosed with PCOS based on the Rotterdam 2003 consensus definition, and reinforced with ultrasound examinations that show polycystic ovary symptoms. Diagnosis is performed by a specialist in Obstetrics and Gynecology. Age data is taken from medical record and IMT data is calculated based on formula body weight/height2. Data analysis was done by unpaired t test. Mean age of study subjects: 32.21 ± 0.99 years female PCOS and 32.80 ± 0.516 years of non-PCOS group of women, unpaired t-test results were not significantly different (p> 0.05). Mass Index PCOS group 24.425 ± 0.585 Kg/m2 and 22.840 ± 0.494 Kg/m2 non-PCOS group, unpaired t-test results were significantly different (p <0.05). Conclusion of this research was in the PCOS women group had significantly higher BMI rates than the group non PCOS woman.

Profil Asupan Minum pada Anak Prasekolah di Daerah Urban dan Rural di Indonesia dan Faktor-faktor yang Memengaruhinya Titis Prawitasari; Bernie Endyarni Medise; Diana Sunardi; Dewi Friska; Erfi Prafiantini; Rizki Yusrini Pohan; Budi Wiweko
Sari Pediatri Vol 22, No 4 (2020)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp22.4.2020.236-42

Latar belakang. Asupan minum yang kurang akan berdampak terhadap performa fisik dan kognitif serta dapat menimbulkan manifestasi klinis, seperti pusing, lesu, dan gangguan konsentrasi. Anak memiliki proporsi cairan tubuh yang lebih tinggi dibandingkan dewasa. Hingga saat ini belum ada data mengenai kecukupan asupan minum anak prasekolah di Indonesia.Tujuan. Mengetahui kecukupan asupan minum anak prasekolah di daerah urban dan rural di Indonesia.Metode. Penelitian dengan desain potong lintang dilakukan pada bulan Januari-Maret 2016 di Jakarta dan Maluku pada anak usia 36-72 bulan. Perhitungan jumlah cairan dilakukan dengan mencatat jumlah yang diminum dalam 7 Day-Fluid Diary Record. Asupan minum total ditentukan berdasarkan jumlah yang dikonsumsi dari semua kategori dan sesuai dengan angka kecukupan gizi (AKG) 2019.Hasil. Sebanyak 585 anak mengikuti penelitian ini dengan median asupan minum adalah 1133,1 (85-2991,4) mL/hari dan jenis asupan paling tinggi adalah air putih. Subjek yang tinggal di daerah urban mempunyai faktor risiko lebih rendah untuk mengalami asupan minum yang kurang (RR=0,580; 95%IK: 0,418-0,807; p=0,001). Demikian pula semakin muda usia subjek, maka semakin kecil kemungkinan untuk mengalami kejadian asupan minum yang kurang (RR =0,497; 95%IK: 0,356-0,694; p=0,000).Kesimpulan. Rerata asupan minum anak usia prasekolah di Indonesia sedikit lebih rendah dari anjuran AKG. Anak prasekolah berusia â‰¥54 bulan dan anak yang tinggal di area rural lebih berisiko mengalami kekurangan asupan minum.

Fertility Preservation: Save Our Hope for the Future Itâ€™s Time to Rethink... Budi Wiweko
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 4, October 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Ovarian Tissue Vitrification as a Method for Ovarian Preservation in Women with Cancer: an Analysis of Granulose Cell Apoptosis Budi Wiweko; Huthia Andriyana; Achmad Aulia
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 2, April 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To obtain the effective method of ovarian function preservation with granulose cell apoptosis assessment. Ovarian tissue vitrification became a method for ovarian function preservation in women with cancer. This technique can be done anytime without delay on cancer therapy both in prepubertal and unmarried patient. It can also store many primordial follicles. Ovarian tissue vitrification study is still limited to animal test and there are no data about apoptosis assessment after ovarian vitrification in human ovary. Method: This quasi experimental study was held in Department of Obstetrics and Gynecology Faculty of Medicine University of Indonesia - Dr. Cipto Mangunkusumo General Hospital and Fatmawati Hospital Jakarta from March 2012 to May 2015. Ovaries from thirteen women between 31 and 37 years old who underwent oophorectomy with gynecological indication were examined. Result: There was no morphological difference between follicles from fresh and warmed-vitrified ovaries. The mean protein Bax expression on the fresh ovaries assessed in the form of H-score was 1.66 (SD 0.14) compared with 1.68 (SD 0.13) on the warmedvitrified group (p=0.165). The mean protein Bcl-2 expression on the fresh ovaries examined in the form of H-score was 1.73 (SD 0.10) compared with 1.71 (SD 0.10) on the warmed-vitrified group (p=0.068). Conclusion: Ovarian tissue vitrification does not affect the Bax and Bcl-2 expression on human ovary. [Indones J Obstet Gynecol 2016; 4-2: 88-92] Keywords: apoptosis, bax, Bcl-2, ovarian tissue vitrification

Relation between CYP17 Polymorphism and Hyperandrogenemia in Polycystic Ovarian Syndrome Budi Wiweko
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 1, January 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (62.763 KB)

Objectives: To find 5-untranslated region polymorphism of CYP17 gene and its connection with hyperandrogenemia in polycystic ovarian syndrome. Methods: A cross sectional descriptive study with consecutive random sampling method. Body mass index, ovarian morphology by ultrasonography, fasting insulin level, fasting blood glucose level, 17-hydroxyprogesterone level, total testosterone level, serum hormone binding globulin level, and CYP17 gene polymorphism in 45 subject with PCOs and 45 control subject who attend Yasmin clinic of Cipto Mangunkusumo General Hospital with menstruation problems were measured. CYP17 gene polymorphism was evaluated using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method with MspA1 restriction enzyme. Results: In PCOs group, the genotype distribution were; 11.1% subject with genotype CC, 71.1% subject with genotype TC and 17.8% subject was wild type TT. In non PCOs group, the genotype distribution for CC, TC and TT respectively were 13.3%, 46.7% and 40%. There was significant difference between both group in distribution of TC and TT genotype, with p value 0.013. Frequencies of allele c and allele t in PCOs group were 47% and 53%. In non PCOs group, frequency of allele c and t were 37% and 63%. There were tendency for higher frequency of allele c in the PCOs group but the difference was not statistically significant. Median FAI value for genotype CC homozygote, TC heterozygote and TT homozygote in PCOs group respectively were; 6.82 (6.07 - 8.23); 5.59 (0.25 -21.45) and 4.74 (3.48 - 8.88). There was tendency for increase FAI value in PCOs group corresponds to variant allele, but the result was not statistically different. Conclusion: There were higher proportion of CC homozygote and TC heterozygote genotype in PCOs patient with tendency of increasing FAI value. [Indones J Obstet Gynecol 2011; 35-1: 3-7] Keyword: polycystic ovarian syndrome, free androgen index, CYP17 polymorphism

Not only embryo quality but also Endometrial Thickness Contributes to IVF outcome: a retrospective study of all IVF cycles in Yasmin Clinic, Jakarta, Indonesia Budi Wiweko
Indonesian Journal of Obstetrics and Gynecology Volume. 34, No. 1, January 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (35.141 KB)

Objective: To study the endometrial thickness and embryo quality during In Vitro Fertilization (IVF) cycles in predicting IVF outcome. Methods: This retrospective study involved 206 infertile patients undergoing 218 IVF cycles in Yasmin Clinic, Dr. Cipto Mangunkusumo National Referral Hospital, Jakarta, Indonesia. All IVF cycles were performed from January 2005 until May 2009. The outcome of this study is the clinical pregnancy following IVF cycles. The endometrial thickness was measured on the day of human chorionic gonadotrophin (hCG) administration. The number of embryos that developed â‰¥ 8 cells on cleavage II represented as the embryo quality. Results: There were 51 among 218 cycles (23.4%) resulted in pregnancy. The endometrial thickness on day of hCG administration was significantly higher in pregnant group compared to non-pregnant group (11.49Â±1.97 mm versus 10.13Â±1.93mm; p

Co-Authors Achmad Aulia Achmad K. Harzif Achmad K. Harzif Achmad K. Harzif Achmad Kemal Achmad Kemal Harzif Ade Jamal Agustina, Elizabeth Ahmad Aulia Aldri Frinaldi Ali Akbar Septiandri Andon Hestiantoro Anto Satriyo Nugroho Aprilia Asthasari Siregar Aria Kekalih Arief Budiono Ario Legiantuko Ariyati, Ira Asmarinah Atha Luthfi Aulia, Achmad Azali, Chairul Nurdin Azharul Yusri Bagastoro, Aswan Bernie Endyarni Medise Bram Pradipta Caroline G. Puspita Chiprion, Ariel Timy Christopher Yo, Edward Cynthia A. Susanto Dewi Ananta Hakim Dewi Friska Diana Sunardi Dwi A. Suryandari Dwi A. Suryandari Dwi Anita Suryandari Eliza Mansyur Endy M. Moegni Erfi Prafiantini Fadlika Harinda Faradina, Anindita Abigail Gita Pratama Hari Kurniawan, Riyan Hartanto Bayuaji Hartanto Bayuaji Herbert Situmorang Herbert Situmorang Huthia Andriyana Huthia Andriyana I Putu Gde Sanjaya, I Putu Indah S. Widyahening Irzanti, Alisha Nurdya Ivan Rizal Sini, Ivan Rizal Joedo Prihartono Judi Januadi Endjun Kanadi Sumapradja Kemal, Achmad Khatimah, Husnul Kurniati, Mala Legiantuko, Ario Luluk Yunaini Luthfi, Atha Mala Kurniati Melva Louisa Mila Maidarti Mohammad Baharuddin Muharam Natadisastra Muharam Natadisastra Muharam Natadisastra, Raden Muharam, R Mushlihani Mushlihani Mutia, Heidi Dewi Nur Rasyid Nurbaeti, Putri Nurdya Irzanti, Alisha Panghiyangani, Roselina Ponco Birowo Prini Diandara Garinasih Pudji Sari Puspawardani, Aisyah Retno Puspita Eka Wuyung Putri Chairani Eyanoer, Putri Chairani R. Muharam Rahmad Mulyadi, Rahmad Raymond R. Tjandrawinata Raymond Surya Retno A. Werdhani Rizki Yusrini Pohan Robert H. Purwaka, Robert H. Sarah Chairani Zakirah Sayogo, Atikah Silvana, Vita Suratih, Ni Made Desy Susanto, Cynthia A. Tita Yuningsih Titis Prawitasari, Titis Trinovita Andraini Ummah, Nafi'atul Veinardi Madjid Vita Silvana Winnugroho Wiratman, Manfaluthy Hakim, Tiara Aninditha, Aru W. Sudoyo, Joedo Prihartono Wisnu Jatmiko Yanfaunnas, Atika Mahira Yo, Edward Christopher Yurnadi Yurnadi Zakirah, Sarah Chairani

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