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Antioxidant Activity in Pharmaceutical Biotechnology Products in The Form of Formulations and Preparations of Telang Flower Kombucha Hand Soap (Clitoria ternatea L) Maigoda, Tonny Cortis; Hariadi, Hari; Triyono, Agus; Rezaldi, Firman; Sugiono, Sugiono; Saifullah, Ipul; Munir, Misbakhul; Kurniawan, Maskun; Rohmatulloh, Rizal; Yenny, Ratna Fitry; Pamungkas, Barolym Tri; Amin, Suseno; Judiono, Judiono
Jurnal Biologi Tropis Vol. 24 No. 2 (2024): April - Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i2.7195

Abstract

Free radicals need to be handled and even prevented so that they are not exposed to the skin, especially the hands. One solution to preventing the exposure of free radicals to the skin of the hands is to wash your hands with herbal soap which is made from the active ingredient of telang flower kombucha. Telang flower kombucha was designed as an active ingredient in the formulation and hand washing soap preparation in this research has been proven as a pharmaceutical biotechnology product in warding off free radicals. This research was designed by making a formulation and preparation of telang flower kombucha hand washing soap at concentrations of 20%, 30% and 40% then measuring it using UV-Vis spectrophotometry. Based on statistical analysis, especially post hoc analysis of pharmaceutical biotechnology products in the form of formulations and preparations of telang flower kombucha hand washing soap at a concentration of 40%, it is significantly different from 20% and 30% as a source of antioxidants.
FORMULASI DAN UJI ANTIDIARE SEDIAAN PATCH TRANSDERMAL EKSTRAK DAUN SENGGANI (Melastoma malabathricum L.) TERHADAP KELINCI Winata, Hanafis Sastra; Abadi, Hafizhatul; Leny, Leny; Andry, Muhammad; Ngete, Ani Florida; Yudianto, Tri; Nurjanah, Ayu; Pamungkas, Barolym Tri; Gumilar, Roni
AGRIBIOS Vol 22 No 2 (2024): November
Publisher : Program Studi Agribisnis Fakultas Pertanian

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36841/agribios.v22i2.5494

Abstract

One plant that has been used for traditional medicine with good results is Melastoma (Melastoma malabatricum L.). The plant known as Melastoma has three active compounds: tannins, saponins, and flavonoids. Melastoma leaves work well to cure diarrhoea. Adhesive patches with medication applied topically are called transdermal patches. Melastoma leaf extract transdermal patch formulations were utilised in this study, which employed laboratory experimental techniques. The potential of Melastoma leaf extract transdermal patch preparation formula as an antidiarrheal for rabbits was the subject of the study. Concentrations of extract: 10%, 20%, and 30%. Organoleptic testing, pH tests, weight uniformity tests, moisture tests, thickness tests, and fold resistance tests were the preparatory assessment parameters that were conducted. The characteristics of the antidiarrheal test were timing of diarrhoea occurrences, consistency of the stool, frequency of diarrhoea, and length of diarrhoea, all of which were monitored for six hours. The evaluation of the Melastoma leaf extract transdermal patch formulation demonstrated a significant difference, namely <0.05, according to the results of the ANOVA data analysis. The antidiarrheal test parameters had a significant difference between each concentration, namely <0.05, according to the findings of the ANOVA data analysis. The conclusions was possible to use a transdermal patch formulation of Melastoma leaf extract (Melastoma malabathricum L.) at a 30% concentration to prevent diarrhoea by making stools softer.