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All Journal BIOTIK: Jurnal Ilmiah Biologi Teknologi dan Kependidikan Jurnal Biologi Tropis Jurnal Gizi Kerja dan Produktivitas Jurnal Ilmiah Agribios JAGO TOLIS : Jurnal Agrokompleks Tolis TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora Abdimas Indonesian Journal Journal of Applied Plant Technology Journal of Tropical Pharmacy and Chemistry Jurnal Farmasi Galenika Jurnal Kesehatan Tujuh Belas (Jurkes TB)
Pamungkas, Barolym Tri
Program Studi Apoteker, Fakultas Farmasi, Universitas Mulawarman, Kalimantan Timur, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Antioxidant Activity in Pharmaceutical Biotechnology Products in The Form of Formulations and Preparations of Telang Flower Kombucha Hand Soap (Clitoria ternatea L) Maigoda, Tonny Cortis; Hariadi, Hari; Triyono, Agus; Rezaldi, Firman; Sugiono, Sugiono; Saifullah, Ipul; Munir, Misbakhul; Kurniawan, Maskun; Rohmatulloh, Rizal; Yenny, Ratna Fitry; Pamungkas, Barolym Tri; Amin, Suseno; Judiono, Judiono
Jurnal Biologi Tropis Vol. 24 No. 2 (2024): April - Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i2.7195

Abstract

Free radicals need to be handled and even prevented so that they are not exposed to the skin, especially the hands. One solution to preventing the exposure of free radicals to the skin of the hands is to wash your hands with herbal soap which is made from the active ingredient of telang flower kombucha. Telang flower kombucha was designed as an active ingredient in the formulation and hand washing soap preparation in this research has been proven as a pharmaceutical biotechnology product in warding off free radicals. This research was designed by making a formulation and preparation of telang flower kombucha hand washing soap at concentrations of 20%, 30% and 40% then measuring it using UV-Vis spectrophotometry. Based on statistical analysis, especially post hoc analysis of pharmaceutical biotechnology products in the form of formulations and preparations of telang flower kombucha hand washing soap at a concentration of 40%, it is significantly different from 20% and 30% as a source of antioxidants.
FORMULASI DAN UJI ANTIDIARE SEDIAAN PATCH TRANSDERMAL EKSTRAK DAUN SENGGANI (Melastoma malabathricum L.) TERHADAP KELINCI Winata, Hanafis Sastra; Abadi, Hafizhatul; Leny, Leny; Andry, Muhammad; Ngete, Ani Florida; Yudianto, Tri; Nurjanah, Ayu; Pamungkas, Barolym Tri; Gumilar, Roni
AGRIBIOS Vol 22 No 2 (2024): November
Publisher : Program Studi Agribisnis Fakultas Pertanian

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36841/agribios.v22i2.5494

Abstract

One plant that has been used for traditional medicine with good results is Melastoma (Melastoma malabatricum L.). The plant known as Melastoma has three active compounds: tannins, saponins, and flavonoids. Melastoma leaves work well to cure diarrhoea. Adhesive patches with medication applied topically are called transdermal patches. Melastoma leaf extract transdermal patch formulations were utilised in this study, which employed laboratory experimental techniques. The potential of Melastoma leaf extract transdermal patch preparation formula as an antidiarrheal for rabbits was the subject of the study. Concentrations of extract: 10%, 20%, and 30%. Organoleptic testing, pH tests, weight uniformity tests, moisture tests, thickness tests, and fold resistance tests were the preparatory assessment parameters that were conducted. The characteristics of the antidiarrheal test were timing of diarrhoea occurrences, consistency of the stool, frequency of diarrhoea, and length of diarrhoea, all of which were monitored for six hours. The evaluation of the Melastoma leaf extract transdermal patch formulation demonstrated a significant difference, namely <0.05, according to the results of the ANOVA data analysis. The antidiarrheal test parameters had a significant difference between each concentration, namely <0.05, according to the findings of the ANOVA data analysis. The conclusions was possible to use a transdermal patch formulation of Melastoma leaf extract (Melastoma malabathricum L.) at a 30% concentration to prevent diarrhoea by making stools softer.
UJI DAYA HAMBAT PERTUMBUHAN JAMUR PATOGEN DERMATOFITA SPESIES Trycopyton mentagrophytes dan Trycophyton rubrum DARI EKSTRAK ETANOL 96% BUNGA KECOMBRANG Octaviana Dyah Oentari; Andri Tri Cahyono; Usman Setiawan; Barolym Tri Pamungkas; Sinta Wisma Sari
Jurnal Kesehatan Tujuh Belas (Jurkes TB) Vol. 3 No. 1 (2021): November 2021
Publisher : Sekolah Tinggi Ilmu Kesehatan Tujuh Belas, Karanganyar, JAwa, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Dermatophytes are a skin disease caused by mycosis or fungi found on the skin. This fungus has the potential to grow in tropical environments and high humidity. Indonesia is a part of the country that has a tropical environment and high humidity, so it has the potential for disease and skin infections caused by pathogenic fungi. Trycophyton mentagrophytes and Trycophyton rubrum are pathogenic fungi that can cause dermatophytes. Long-term use of synthetic drugs causes resistance to the fungus and also irritation of the skin organs, so traditional treatments need to be reaffirmed which have been used for generations. One traditional or herbal-based treatment is to use kecombrang flowers which are extracted through 96% ethanol. This is because the phytochemical content of the kecombrang plant has been proven to have various pharmacological activities, especially in inhibiting the growth of pathogenic fungi. This research aims to provide the latest scientific information regarding the growth inhibitory power of pathogenic fungi from 96% ethanol extract of kecombrang flower plant organs in inhibiting the growth of the two test pathogenic fungi. This resistance test was carried out using the well method. The results of this research have proven that the ethanol extract of kecombrang flowers correlates positively and comprehensively as an antidermatophyte and it can be concluded that a concentration of 15% is the optimal treatment as an antidermatophyte
Aktivitas Antibakteri Fraksi Etil Asetat Daun Sirsak (Annona muricata L.) Terhadap Staphylococcus aureus dan Escherichia coli Secara In Vitro Pamungkas, Barolym Tri; Yulita, Victoria; Ibrahim, Arsyik
JURNAL FARMASI GALENIKA Vol 13 No 1 (2026): Jurnal Farmasi Galenika Volume 13 No 1
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v13i1.437

Abstract

The widespread emergence of antimicrobial resistance has intensified the search for plant-derived antibacterial agents as therapeutic alternatives. Soursop (Annona muricata L.) is widely recognised in Indonesian ethnomedicine as a plant effective against infections, owing to its rich and diverse secondary metabolite profile. This study was designed to examine the growth-inhibitory capacity of the ethyl acetate leaf fraction of soursop against pathogenic bacteria Staphylococcus aureus and Escherichia coli in vitro, while concurrently identifying the fraction concentration producing the greatest inhibitory effect. Antibacterial testing employed the agar diffusion disc technique at three fraction concentrations: 10%, 20%, and 40% (w/v). The resulting inhibition zone diameters were subjected to one-way ANOVA and Duncan's Multiple Range Test. All concentrations successfully suppressed the growth of both test organisms; the maximum inhibition was recorded at 40%, with mean inhibition zone diameters of 4.49 mm for S. aureus and 4.06 mm for E. coli. Statistical analysis confirmed a highly significant treatment effect (Fcount = 21.02; p<0.01). Accordingly, the ethyl acetate fraction of soursop leaves demonstrates dose-dependent antibacterial potential worthy of further development.
Co-Authors Abadi, Hafizhatul Agus Triyono Agustiansyah, Lucky Dita Andri Tri Cahyono Angga Cipta Narsa Ash Siddiq, Muhammad Nuzul Azhim Ayu Safitri Ayu Safitri Badawi, Satriani Bahar, Zulhaerana Erni Suminar Fahrul Rozi Fajar Hidayanto, Fajar Gumilar, Roni Hari Hariadi Hari Hariadi, Hari Ibrahim, Arsyik Ipul Saifullah, Ipul Saifullah Judiono Judiono Kurniawan, Maskun Leny Leny, Leny Lucky Dita Agustiansyah M. Fariz Fadillah M. Fariz Fadillah M. Fariz Fadillah Mardianto Maigoda, Tonny Cortis Majiding, Chaidir Masyhuri Maritha, Vevi Maskun Kurniawan Maskun Kurniawan Misbakhul Munir Misbakhul Munir, Misbakhul Munir Mochammad Imron Awalludin Moelyono Muktiwardojo Muhammad Andry Muhammad Irfan Ngete, Ani Florida Novi Ayuwardani, Novi Ayuwardani Nurjanah, Ayu Octaviana Dyah Oentari Raisa Fadila Ratna Fitri Yenny, Ratna Fitri Ratna Fitry Yenny, Ratna Fitry Yenny Rifkarosita Putri Ginaris Rizal Rohmatulloh, Rizal Rohmatulloh Rohmatulloh, Rizal Saifullah, Ipul Sinta Wisma Sari Sugiono Sugiono Sugiono Sugiono, Sugiono Sugiono Suseno Amin, Suseno Susiyanti Susiyanti Syariful Mubarok Tina Rostinawati Trisnawati, Desi Usman Setiawan Vevi Maritha Vevi Maritha, Vevi Maritha Winata, Hanafis Sastra Yenny, Ratna Fitry Yudianto, Tri Yulita, Victoria