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All Journal Jurnal Ilmiah Farmasi Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Pharmaciana: Jurnal Kefarmasian Jurnal Farmasi Andalas Jurnal Sains dan Teknologi Farmasi Jurnal Riset Kimia INDONESIAN JOURNAL OF PHARMACY Science and Technology Indonesia JOPS (Journal Of Pharmacy and Science) JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Ilmu Kedokteran dan Kesehatan JFIOnline Jurnal Ilmu Kefarmasian Indonesia Jurnal Farmasi Higea Majalah Farmasetika JPK: Jurnal Proteksi Kesehatan Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Pharmaceutical And Biomedical Sciences Journal (PBSJ) Medical Sains : Jurnal Ilmiah Kefarmasian Journal of Pharmaceutical and Sciences. Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Erizal Zaini
Departemen Farmasetik, Fakultas Farmasi, Universitas Andalas, Padang 25163
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Journal : Jurnal Riset Kimia

 1 
KARAKTERISASI FISIKOKIMIA DAN LAJU DISOLUSI DISPERSI PADAT IBUPROFEN DENGAN PEMBAWA POLIETILENGLIKOL 6000 Zaini, Erizal; Rahmi Nofita, Rahmi x; -, Salman; Kurniati, Irna
Jurnal Riset Kimia Vol 4, No 1 (2010): September
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v4i1.63

Abstract

 Solid dispersions of the antiinflamation drug ibuprofen and polyethylene glycol 6000 (PEG 6000) were prepared by the melting method in order to increase the dissolution rates of this poorly water-soluble compound. The temperature/composition phase diagram of binary system was analyzed by termal analysis hot-stage microscopy, showing an eutectic formation. Polarized light hot stage microscopy and X-ray-powder diffraction confirmed, that solid dispersion technique decrease the crystalliny of ibuprofen after melting and solidifying of a 4/6 (w/w) mixture of ibuprofen and polyethylene glycol 6000 respectively, which the results enhanced dissolution rates compared to the physical mixtures and ibuprofen intact. However, no such chemical interactions in the solid state were confirmed by FTIR spectra which showed the presence of ibuprofen crystalline in solid dispersion.   
MANUFACTURE OF PLASTICS FILM CONTAINING OF POLYSTIRENE, POLYCAPROLACTONE, POLY(3-HIDROKSIBUTYRATE-CO-3- HIDROXYVALERATE) AND BIODEGRADATION STUDY IN OCEAN WATER Dewi, Asiska Permata; Zaini, Erizal; Djamaan, Akmal
Jurnal Riset Kimia Vol 7, No 2 (2014): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v7i2.167

Abstract

 ABSTRACTThe manufacture of a biodegradable plastics film containing of polymer synthetic polystyrene(PS) and biopolymer of polycaprolactone (PCL), poly(3-hydroxybutyrate-co-3-hydroxyvalerate)[P(3HB-ko-3HV)] and biodegradation study in ocean water has been carried out. Plastics filmcontaining of PS/PCL/P(3HB-ko-3HV) produced by blending techniques followed by solventcasting with ratios were of 100/0/0, 95/5/0, 95/0/5, 90/5/5, 85/10/5, 85/5/10. This testing wasconducted based on immersion test method recommend by American Society for Testing andMaterials. Poly blend plastics film PS/PCL/P(3HB-ko-3HV) were characterized by tensilestrength, thermal properties and SEM analysis. The profiles of the rate biodegradation view byweight reduction of the tested plastic film for 1-7 weeks period. Tensile strength analysisshowed the decreasing of tensile strength with the addition of P(3HB-ko-3HV). Thermalanalysis showed a decreasing in the melting point with the addition of PCL and P(3HB-co-3HV). SEM micrograph showed the destruction occurred and erosion at surface of plastic filmduring observation time. The rate of biodegradation showed that increasing of PCL and P (3HBco-3HV) in a mixture of plastic film, so biodegradation increased.Keywords: polystyrene, polycaprolactone, poly(3-hidroxybutyrate-co-3-hydroxyvalerate),biodegradation, film plastic.
KARAKTERISASI FISIKOKIMIA DAN LAJU DISOLUSI DISPERSI PADAT IBUPROFEN DENGAN PEMBAWA POLIETILENGLIKOL 6000 Erizal Zaini; Rahmi x Rahmi Nofita; Salman -; Irna Kurniati
Jurnal Riset Kimia Vol. 4 No. 1 (2010): September
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v4i1.63

Abstract

 Solid dispersions of the antiinflamation drug ibuprofen and polyethylene glycol 6000 (PEG 6000) were prepared by the melting method in order to increase the dissolution rates of this poorly water-soluble compound. The temperature/composition phase diagram of binary system was analyzed by termal analysis hot-stage microscopy, showing an eutectic formation. Polarized light hot stage microscopy and X-ray-powder diffraction confirmed, that solid dispersion technique decrease the crystalliny of ibuprofen after melting and solidifying of a 4/6 (w/w) mixture of ibuprofen and polyethylene glycol 6000 respectively, which the results enhanced dissolution rates compared to the physical mixtures and ibuprofen intact. However, no such chemical interactions in the solid state were confirmed by FTIR spectra which showed the presence of ibuprofen crystalline in solid dispersion.   
MANUFACTURE OF PLASTICS FILM CONTAINING OF POLYSTIRENE, POLYCAPROLACTONE, POLY(3-HIDROKSIBUTYRATE-CO-3- HIDROXYVALERATE) AND BIODEGRADATION STUDY IN OCEAN WATER Asiska Permata Dewi; Erizal Zaini; Akmal Djamaan
Jurnal Riset Kimia Vol. 7 No. 2 (2014): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v7i2.167

Abstract

 ABSTRACTThe manufacture of a biodegradable plastics film containing of polymer synthetic polystyrene(PS) and biopolymer of polycaprolactone (PCL), poly(3-hydroxybutyrate-co-3-hydroxyvalerate)[P(3HB-ko-3HV)] and biodegradation study in ocean water has been carried out. Plastics filmcontaining of PS/PCL/P(3HB-ko-3HV) produced by blending techniques followed by solventcasting with ratios were of 100/0/0, 95/5/0, 95/0/5, 90/5/5, 85/10/5, 85/5/10. This testing wasconducted based on immersion test method recommend by American Society for Testing andMaterials. Poly blend plastics film PS/PCL/P(3HB-ko-3HV) were characterized by tensilestrength, thermal properties and SEM analysis. The profiles of the rate biodegradation view byweight reduction of the tested plastic film for 1-7 weeks period. Tensile strength analysisshowed the decreasing of tensile strength with the addition of P(3HB-ko-3HV). Thermalanalysis showed a decreasing in the melting point with the addition of PCL and P(3HB-co-3HV). SEM micrograph showed the destruction occurred and erosion at surface of plastic filmduring observation time. The rate of biodegradation showed that increasing of PCL and P (3HBco-3HV) in a mixture of plastic film, so biodegradation increased.Keywords: polystyrene, polycaprolactone, poly(3-hidroxybutyrate-co-3-hydroxyvalerate),biodegradation, film plastic.
Co-Authors -, Salman Adhitya Jessica Agusri Boestari Agustina, Annisa Akmal Djamaan Amri Bakhtiar Andarifera, Alya Zahira Annisa Agustina Aprilianti, Hizra Dwi Arif, Zhafira Asiska Permata Dewi Asiska Permata Dewi Asiska Permatadewi Auzal Halim Auzal Halim Azhoma Gumala Azzahra, Cindy Maynia Ben, Elfi Sahlan Deni Anggraini Deni Noviza Dhea Sultana Lutfiyah DINI HANIFA, DINI Dwi Setyawan Ellyza Nasrul Elpa Giovana Zola Elsa Badriyya Elvi Rahma Yulisman Elvita Sari Fadhila, Muthia Fauzi Saputra Fauziah, Gusrina Fifi Harmely Firdaus, Wahyu Alfath Friardi Ismed Gaesari, Sherly Rahmah Gaesari, Sherly Rahmah Ghiffari, Habibie Deswilyaz Hansen Nasif Haq AH, Ahdi Dinil Hasmiwati Helen Sonita Henny Lucida Hulwa Salsabila Ihsan, Ikhwanul Ima Kurniati Irna Kurniati Jessica, Adhitya Kiki Rizky Wirza Kurniati, Irna Lili Fitriani Mai Efdi Maria Dona Octavia Melanny Ika Sulistyowaty Melisa Melisa Melzi Octaviani Mohd Amin, Mohd Cairul Iqbal Muhammad Taher Muthia Fadhila Mutiara Zulkarnaini Najmi Hilaliyati Netty Novitasari Nova Syafni Novica Sari Prameswari, Putu Pradnya Mimba Raden Joko Kuncoroningrat Susilo Rahmadasmi, Nola Rahmadevi Rahmi Nofita Rahmi Yosmar Rahmi Yosmar Resva Meinisasti Revila, Gusti Reza Safitri Rifka Naura Rini Agustin Rini Agustin Rizky, Fattihatul Rosaini, Henni Rose Intan Perma Sari Rustini Rustini Rustini Rustini S, Agnes Saafrida Saafrida Saafrida Saafrida Saafrida Salman - Salman - Salman Salman Salman Umar Sari, Elvita Sayyidina, Fasqina Simbolon, Clara Alverina Sundani N. Soewandhi Sundani N. Soewandhi, Sundani N. Syofyan Syofyan SYUKRAN HAMDENI Syukriati Chaira Tahta Amrillah Trisfa Augia Try Andy Sahputra Try Andy Sahputra Usman, Hendrizal Uswatul Hasanah Uswatul Hasanah, Uswatul Verlia Nisrina Putri Vike Zulia Putri Vina Oktavia Yeni Novita Sari Yeyet C. Sumirtapura Yufri Aldi Yuliza, Sukma Yuska Noviyanty Zahara Gayo Zidan, Sabry A. H. Zulhadjri Zulhadjri