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Dwi Wahyuni
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TOKSISITAS EKSTRAK TERPURIFIKASI DAUN PULUTAN (Urena lobata L.) FRAKSI ETANOL TERHADAP MORTALITAS LARVA NYAMUK Aedes Aegypti Indah Atika Amalia; Dwi Wahyuni; Kamalia Fikri
saintifika Vol 23 No 2 (2021)
Publisher : FKIP Universitas Jember

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Abstract

Dengue hemorrhagic fever (DHF) is a disease that is a major public health problem throughout the world. Indonesia is one of the countries with the largest dengue cases in the world. One of the largest dengue cases in Indonesia is in East Java Province whic h reached 5,733 cases. Dengue fever is transmitted to humans through the Aedes aegypti mosquito infected with the dengue virus. The way to control DHF is to control the vector, namely by breaking the mosquito life cycle using selective and safe biological larvicides. Plants that have potential as biological larvicides are pulutan ( Urena lobata L.) especially the leaves. Pulutan leaves are used as biological larvicides through an extract purification process. This study aims to determine the toxicity of puri fied extract of pulutan leaf ( Urena lobata L.) ethanol fraction on mortality of Aedes aegypti mosquito larvae. Toxicity based on WHO standard (2002), was determined by LC 50 of purified extract of pulutan leaf ethanol fraction on mortality of Aedes aegypti mosquito larvae. Results Based on probit analysis using the Minitab 14 application software, the LC 50 value was 905,36 5 ppm with a lower limit of 810 , 626 ppm and an upper limit o f 992 , 277 ppm. According to this study, purified extract of pulutan leaf ethanol fraction was toxic to Aedes aegypti mosquito larvae and had a larvicidal effect
PERBEDAAN TOKSISITAS EKSTRAK DAUN SIRIH (Piper betle L.) DENGAN EKSTRAK BIJI SRIKAYA (Annona squamosa L.) TERHADAP LARVA NYAMUK Aedes aegypti L. Dwi Wahyuni; Intania Loren
saintifika Vol 17 No 1 (2015)
Publisher : FKIP Universitas Jember

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Abstract

Dengue Fever is a public health problem that is more widespread endemic area for morbidity is high enough into something that must be addressed immediately.The way to solve this desease chemically can make this mosquito becomes resistant. To solve this problem, it needs to find an alternative way in which it can be a natural insecticide that is safe like compounds that comes from Piper betle leaves and Annona squamosa seed. The active compounds of Piper betle leaves that are mixed with the active compounds of Annona squamosa seeds can be used as bioinsecticide. Piper betle leaves contain the active compounds of saponin, alkaloid, flavonoid and tannin, while Annona squamosa seeds contain theactive compounds of annonacin, squamocin, asimisin and alkaloid. This research aimsed to investigate the toxicity of themixture of the Piper betle leaves extract and Annona squamosa seeds againet Aedes aegypti mosquito larvae and tocompare the toxicity of the extract mixture and single extract. The method of this research used complete random design bythree repetitions. The concentratios used were 300, 600, 900, 1200 and 1500 ppm for Piper betle leaves extract and 5, 10, 50, 70 and 100 ppm for Annona squamosa seeds extract with aquades asthe control. The data were analyzed by using probit analysis to determine the LC50. The LC50 score of the Piper betle leaves extract was 910,38 ppm and the LC50 of the Annona squamosa seeds extract was 20,62 ppm. This result showed that toxicity of Piper betle leaves extract with different Annona squamosa seeds which was toxicity is higher than the toxicity of Piper betle leaves extract.
POTENSI ANTAGONIS BAKTERIA SERRATIA MARCESSCENS TERHADAP BAKTERI STREPTOCOCCUS PYOGENESIS DAN BAKTERI VIBRIO CHOLERA SECARA IN VITRO Muhammad Efendi; Dwi Wahyuni; Imam Mudakir
saintifika Vol 18 No 2 (2016)
Publisher : FKIP Universitas Jember

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Abstract

In indonesia, infection diseases are a very high problem among the public, one the common infectious diseases suffered by the Indonesian community is imflamtion of the tonsils caused by Streptococcus pyogenesis and Cholera caused by Vibrio cholera. The use of chemical antibiotics will have a negative impact in health, so necessary alternative replecement of natural antibiotics by Serratia mercescens can pruduce prodigiosin. This reseacrh was to test the potential of Serratia mercescens antagonist against Streptococcus phyogenesis and Vibrio cholera in vitro, using Completely Randomized Design with one treatment factor from Serratia mercescens bacteria concentration. The concentration used was 30μm for each bacterial suspension and added positive control in the form of chloramphenicol and negative control of aquades, each of which was repeated 3 repititions. The results were analyzed using one-way ANOVA and continued D- test. The result showed that Serratia mercescens had blocked inhibitability of Streptococcus phyogenesis bacteria with an average resistance of1.1033mm and on Vibrio cholera with an average resistance of 1.2233mm.
Toksisitas Ekstrak Terpurifikasi dengan N-heksan Buah Kecubung (Datura metel L.) terhadap Mortalitas Larva Nyamuk Aedes aegypti Aditya Rico Armyandi; Dwi Wahyuni; Kamalia Fikri
saintifika Vol 24 No 1 (2022)
Publisher : FKIP Universitas Jember

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Abstract

Infectious diseases caused by animal vectors are currently still a health problem in the world even in Indonesia, especially the Aedes aegypti mosquito which is the vector for the spread of dengue fever. Chemical control is still a priority for the community, such as the use of abate. Continuous use of abate can cause resistance to the Aedes aegypti mosquito to the next generation and pollute water conditions. One of the control solutions can be done with natural insecticides such as amethyst fruit (Datura metel L.). The purpose of making purified extracts is to remove unnecessary impurities and get a larger content of active compounds and increase the concentration of active compounds. The concentration of amethyst extract (Datura metel L.) used was a concentration of 100 ppm, 500 ppm, 1000 ppm, 1500 ppm, 1gr abate as a positive control and aquades as a negative control. The amount of Lethal Concentration-50 (LC50) purified extract of amethyst fruit (Datura metel L.) with n-hexane was 494.987 ppm. The active compound content of amethyst fruit (Datura metel L.) in the n-hexane fraction after a phytochemical screening test was carried out was positive for alkaloids, steroids, terpenoids and tannins. The toxicity of the purified extract with n-hexane of amethyst (Datura metel L.) against Aedes aegypti mosquito larvae within 24 hours is considered toxic because it has an LC50 value of less than 1000 ppm.
Toksisitas Ekstrak Terpurifikasi Daun Buas-Buas (Premna serratifolia L.) terhadap Mortalitas Larva Nyamuk Culex sp. Ulmiyatul Alifiah Zahroh; Dwi Wahyuni; Mochammad Iqbal
saintifika Vol 24 No 1 (2022)
Publisher : FKIP Universitas Jember

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Abstract

Culex sp. is a vector of filariasis. Vector control mostly uses chemical insecticides which have a negative impact. Buas-buas plants (Premna serratifolia L.) are one of the plants that have the potential as an alternative to the use of chemical insecticides that have been widely used (as botanical insecticides). Buas-buas leaves (Premna serratifolia L.) contain alkaloids, flavonoids, saponins, and tannins. This study aimed to test the toxicity of the purified extract of buas-buas leaf (Lethal concentration 50) on the mortality of Culex sp. larvae with an exposure time of 24 hours. Serial concentrations of purified extract used were 850, 1350, 1850, 2350, and 2850 ppm with four repetitions. Each treatment used 20 Culex sp. late three to early four instars. Toxicity testing of Culex sp. gives an LC50 result of 1799.77 ppm..
TOKSISITAS GRANULA EKSTRAK BUAH JERUK NIPIS (Citrus aurantifolia L.) TERHADAP MORTALITAS BERUDU (Phyrinoidis aspera) Renny Ria Fitriani; Dwi Wahyuni; Kamalia Fikri
saintifika Vol 19 No 2 (2017)
Publisher : FKIP Universitas Jember

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Abstract

Granules extract of clime fruit (Citrus aurantifolia L.) is a biolarvasida in eradicating Aedes aegypti mosquito larvae L. Granules extract of lime fruit (Citrus aurantifolia L.) can kill mosquito larvae because its content of limonoida, tannin, flavonoid, and volatile oil. The compound is lethal to the larvae which will enter the body of the larvae of the Aedes aegypti L. mosquito which disrupts the systems in its body. The purpose of this article is to determine the safety of lime fruit (Citrus aurantifolia L.) extract granules on non-target animals, namely tadpoles. Tadpole has the same habitat with mosquito larvae so it is done safety test of citrus fruit extract granule (Citrus aurantifolia L.). Tadpole is a larval phase in Amphibi that continues to experience morphological development in water. The initial phase of tadpoles growth is a phase of adaptation to its habitat. Individuals who can not adapt well will experience a faster death. The research method used is laboratory experimental. The analysis used is ANOVA. The independent variables in this study were the variety of granules extract concentration of citrus fruit (Citrus aurantifolia L.). Tadpole mortality became the dependent variable in this study. Tadpole mortality is characterized by tadpoles collapsing at the time of administration of granules. The results showed that the lime extract granules (Citrus aurantifolia L.) proved safe.
Formulation and Antibacterial Activity of Porang (Amorphophallus muelleri Blume) Extract Gel Against Propionibacterium acne Nurshalati Tahar; Dwi Wahyuni; Rabiatul Adawiyah; Khaerani; Munifah Wahyuddin
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol. 6 No. 1 (2023)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v6i1.38744

Abstract

Introduction: The increase in bacterial resistance to antibiotics provides an opportunity to obtain antibacterial compounds from natural ingredients. Porang is a plant belonging to the Araceae family that has potential against Propionibacterium acne. Aims: This study aims to determine the effectiveness of the preparation of porang tuber extract gel against Propionibacterium acne. Methods: The porang were extraction by maceration using ethanol. The extract porang were made gel with various concentration and evaluation their stability and antibacterial activity using disc diffusion method. Result: The hedonic test showed no significant differenece each of formula and stable during storage in two weeks. On the other hand, only formula F2 and F3 can inhibit of Propionibacterium acnee. Conclusion: The porang extract can made of gel and good stability. The formula F2 and F3 have antibacterial activity.
Pengaruh Kompensasi Dan Tunjangan Terhadap Efektivitas Kinerja Babinsa Kodim 1613/Sumba Barat Yuliansa Fitra; Dwi Wahyuni
Bridging Journal of Islamic Digital Economics and Management Vol. 1 No. 1 (2023): November
Publisher : Al-Shobar Publisher, Yayasan Islam Al-Shobar Rawaurip

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Abstract

Artikel ini bertujuan untuk menganalisis pengaruh kompensasi dan tunjangan terhadap efektivitas kinerja Babinsa. Babinsa merupakan anggota TNI AD yang ditempatkan di tingkat desa/kelurahan, bertugas dalam pembinaan wilayah aspek geografi, demografi dan kondisi sosial serta mendukung program pemerintah daerah di wilayah tersebut. Artikel ini disusun dengan mengumpulkan data dari Babinsa yang bertugas di Kodim 1613/Sumba Barat dan menggunakan metode analisis regresi untuk menguji hubungan antara kompensasi, tunjangan, dan kinerja Babinsa. Hasil penelitian menunjukkan bahwa kompensasi yang adil dan memadai serta tunjangan yang cukup berpengaruh positif terhadap kinerja Babinsa. Kompensasi dan tunjangan yang memadai dapat meningkatkan motivasi dan dedikasi Babinsa dalam melaksanakan tugasnya. Selain itu, tunjangan yang sesuai juga dapat memberikan mereka sumber daya yang diperlukan untuk menjalankan tugas-tugasnya dengan efektif. Artikel ini diharapkan memberikan kontribusi dalam memahami pentingnya kompensasi dan tunjangan dalam meningkatkan kinerja Babinsa. Implikasi dari penelitian ini adalah pentingnya pemerintah dan institusi terkait untuk memperhatikan dan memberikan kompensasi dan tunjangan yang sesuai kepada Babinsa demi meningkatkan kinerja dan efektivitas mereka dalam menjalankan tugas-tugasnya di tingkat desa/kelurahan.kompensasi dan tunjangan dalam meningkatkan kinerja Babinsa. Implikasi dari penelitian ini adalah pentingnya pemerintah dan institusi terkait untuk memperhatikan dan memberikan kompensasi dan tunjangan yang sesuai kepada Babinsa demi meningkatkan kinerja dan efektivitas mereka dalam menjalankan tugas-tugasnya di tingkat desa/kelurahan.
Asuhan Keperawatan Pada Pasien Diabetes Mellitus Tipe II Dengan Pemberian Intervensi Terapi Relaksasi Otot Progresif Terhadap Penurunan Kadar Glukosa Darah Di Ruang Cempaka RSUD Kabupaten Tangerang Novita Sariayu Sitompul; Meynur Rohmah; Dwi Wahyuni
DIAGNOSA: Jurnal Ilmu Kesehatan dan Keperawatan Vol. 2 No. 1 (2024): Februari,: Jurnal Ilmu Kesehatan dan Keperawatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59581/diagnosa-widyakarya.v2i1.2766

Abstract

Background: Type 2 diabetes mellitus is a metabolic disorder characterized by an increase in blood sugar due to decreased insulin secretion by pancreatic beta cells or insulin resistance. Difficulty controlling blood sugar levels is a problem experienced by every person with type 2 diabetes mellitus. Several reasons cause uncontrolled blood sugar levels, such as the patient not wanting to exercise, poor diet and negligence in treatment. Management of diabetes mellitus can be done with non-pharmacological therapy in the form of physical exercise. Physical activity will make the body's metabolism work more optimally which will result in blood glucose levels being controlled so that holistic treatment is needed. One of the non-pharmacological physical exercise therapies that can be given to diabetes mellitus sufferers is progressive muscle relaxation techniques. Research method: Implementing Progressive Muscle Relaxation Therapy in Type II Diabetes Mellitus patients to reduce Blood Glucose Levels. Research results: The results of implementation and evaluation for 3 days with Progressive Muscle Relaxation Therapy intervention showed objective and subjective changes in Type II Diabetes Mellitus patients as well as changes in blood glucose levels before and after being given Progressive Muscle Relaxation Therapy. Conclusion: There is a decrease in Blood Glucose Levels after Progressive Muscle Relaxation Therapy.
Asuhan Keperawatan Pada Pasien Diabetes Melitus Dengan Intervensi Terapi Senam Kaki Diabetes Terhadap Penurunan Gejala Neuropati Diabetik Muhamad Saifudin; Meynur Rohmah; Dwi Wahyuni
DIAGNOSA: Jurnal Ilmu Kesehatan dan Keperawatan Vol. 2 No. 1 (2024): Februari,: Jurnal Ilmu Kesehatan dan Keperawatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59581/diagnosa-widyakarya.v2i1.2773

Abstract

Background: Diabetes Mellitus is a heterogeneous disorder characterized by increased glucose levels in the blood. Insulin, a hormone produced by the pancreas, controls glucose levels in the blood by regulating its production and storage (Smeltzer and Bare, 2019). Diabetes Mellitus occurs if the pancreas produces little or no insulin so that the sufferer is forever dependent on external insulin, or if the pancreas continues to produce insulin but the body develops immunity to its effects. Diabetic neuropathy is nerve damage caused by increased blood glucose, which results in decreased blood circulation to cells and decreased nerve cell function. Initial symptoms are paresthesia (prickling, tingling or increased sensitivity) and burning (especially at night). As neuropathy increases, the feet feel numb (numb). Decreased sensitivity to pain and temperature puts neuropathy sufferers at risk of experiencing injury and infection in the feet without knowing it (Smeltzer and Bare, 2019). Foot exercises are activities or exercises carried out by Diabetes Mellitus patients which aim to improve blood circulation so that nutrition reaches the tissues more smoothly, strengthen small muscles, calf muscles and thigh muscles, and overcome the limited joint movement often experienced by Diabetes Mellitus sufferers. Method: The method for writing this final scientific paper is a literature review by examining journals that discuss the effect of diabetic foot exercises on reducing neuropathy symptoms in Diabetes Mellitus sufferers. Results: Based on the results of the implementation carried out by the author, namely encouraging patients to carry out routine extremity movements, namely by carrying out diabetes foot exercise therapy for three consecutive days from 09 to 11 January 2024, differences were found between conditions before and after implementation. The patient data before implementation was that the patient said both feet often felt tingling, the patient said both feet sometimes felt like they were numb, the results of scoring symptoms of diabetic neuropathy were 4, while the patient data after implementation was that the patient complained of tingling both times and feeling like numbness. begins to decrease and the results of scoring symptoms of diabetic neuropathy have decreased, namely to a value of 2, so it can be concluded that there is an influence of diabetic foot exercise therapy on reducing symptoms of diabetic neuropathy in diabetes mellitus sufferers. This is in accordance with the journal that the author studied, namely according to Febrina Angraini S, 2020.
Co-Authors AA Sudharmawan, AA Abd. Rozak Adila Noor Rifa Aditya Rico Armyandi Aditya Rico Armyandi Agustin Syamsianah Ali Syahbana Andi Tenri Sumpala Aris Kastori Frawarna Armaini Armaini Cahyo Tri Atmojo Denny Adrian Nurhuda Deta Mediana, M. Sang Gumilar Panca Putra Deta Mediana, Nita Anggraini Dian Prima Agustina Diemroh Ihsan Dini Aisyafahmi Dwi Arfinanta Edy Soesanto Elfian Zulkarnain Esti Ambar Widyaningrum Evi Kurniawati Fahimul Amri Faizatun Ni’mah Hajar Syifa Fiarani, Hajar Syifa Fiarani Harini Harini Herry Suswanti Djarot Hidayati, Wiwin Sri Humam Humam Ida Kristianingsih Iis Nur Asyiah Imam Mudakir Indah Atika Amalia Indah Atika Amalia Indah Istanti Indrawati Indriyani Indriyani Intania Loren Iyung Cahyono Johanes Parasian John Friadi Kamalia Fikri Karsih Kaslam, Kaslam Khaerani Kholidaziah, Kholidaziah KRISNA KHARISMA PERTIWI Kusriani Prasetyowati La Ode Nggawu La Ode Sidu Marafat Laily Maftuhah Lidia Rosaria Lina Susilowati Luh Putu Ratna Sundari M. Rafli Ishamuddin M. Thery Kesuma Pratama MEIDEZELLA Mey Nurrohmah meynur rohmah Mochammad Iqbal Muhamad Saifudin Muhammad Efendi Muhammad Ilham Kurniawan Muhammad W Pambudi Muhammad Yusuf Pawellangi Munifah Wahyuddin Nadia Pramasari Nila Firmalia Noval Alfiyan Jaya Novita Kumalasari Novita Sariayu Sitompul Nurida Ulin Ni’mah Nurshalati Tahar Nursuci Islamiyah NURUL ISTIQOMAH Petrus Geroda Beda Ama Petrus Geroda Beda Ama Puji Lestari, Tri Rabiatul Adawiyah Rachmita Mustika Putri Rachmita Mustika Putri Renny Ria Fitriani Renny Ria Fitriani Risma Karlina Putri Rita Hayati Rosa J. Hesturini Rosa Juwita Hesturini Sartika Komalasari Siti Murdiyah Slamet Hariyadi Sri Pujiati Suciati Sudarisman Sugiyarto Sugiyarto Suryadi Suswadi Ulmiyatul Alifiah Zahroh Ulmiyatul Alifiah Zahroh Wahyu Anugrah Wenti Dwi Febriani Yeni Gumiati Yuliansa Fitra Yuly Diyan Nur Fajriyah Yuni Purnamasari YUYUN KURNIAWATI Yuyun Kurniawati Zailani , Rinawati