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All Journal Jurnal Sains dan Teknologi Medical Laboratory Technology Journal Health Notions Meditory : The Journal of Medical Laboratory IRJE (Indonesian Research Journal in Education) Jurnal Analis Kesehatan International Journal of Natural Science and Engineering Jurnal Kesehatan Jurnal Farmamedika (Pharmamedica Journal) Performance : Jurnal Bisnis dan Akuntansi Jurnal Pengabdian Kepada Masyarakat (JPKM) Tabikpun Jurnal Pengabmas Masyarakat Sehat Jurnal Pengabdian Masyarakat Sasambo Muhammadiyah Medical Journal Jurnal Pengabmas Masyarakat Sehat JURNAL SKALA HUSADA: THE JOURNAL OF HEALTH JURNAL TUNAS PENDIDIKAN Jurnal Bintang Pendidikan Indonesia SAUJANA : Jurnal Perbankan Syariah dan Ekonomi Syariah PEDAGOGIC: Indonesian Journal of Science Education and Technology Jurnal Ilmu Sosial dan Humaniora Jurnal Info Kesehatan Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
Nur Habibah
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Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : medical laboratory technology journal

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The Efficacy of Green Grapefruit (Vitis Vinifera L) Extracts on Reducing Blood Glucose in a Diabetic Rat Model Habibah, Nur; Rofi'ah, Lisa Khofidatur; Bekti, Heri Setiyo; Dewi, Ni Nyoman Astika; Wilankrisna, Luh Ade; Posmaningsih, Dewa Ayu Agustini
Medical Laboratory Technology Journal Vol. 10 No. 2 (2024): December
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v10i2.606

Abstract

Diabetes mellitus (DM) is a chronic disease in which the pancreas cannot produce enough insulin hormone or when the body cannot use the insulin hormones properly. Green grapes contain flavonoids, anthocyanins, tannins, phenolic acids, and resveratrol and are high in antioxidants that are beneficial in lowering blood glucose levels. This study aims to determine the effectiveness of green grapefruit (Vitis vinifera L) extract in reducing blood glucose levels in a diabetic rat model. This research is a true experiment with a post-test-only control group design, using 24 male Wistar white rats aged 8-12 weeks and weighing 130-200 grams. The rats were divided into three groups: the positive control (I), green grapefruit extract (II), and normal group (III). The results showed that green grapefruit extract effectively reduced blood glucose levels in experimental animals by a percentage of 98.4%. The Independent T-Test showed a value of ρ>0.05 (0.533), so there was no significant difference in glucose levels between green grapefruit extract and positive control. This study concludes that green grapefruit extract was effective at 98.4% in reducing blood glucose levels in the diabetic rat model, compared to the positive control. The promising results of this study need to be continued by establishing a standardized optimal dose, assessing long-term effects, and implementing clinical trials to evaluate efficacy and safety.
Co-Authors Agustina, Praditya Ayu Ahmad Ridhoh Amanda, Futri Anak Agung Sri Agung Aryastuti Apdoludin Apdoludin, Apdoludin Aprilia Maulina Aprilia, Indri Ayu Arjani, I A Made Sri Arjani, Ida Ayu Made Sri Arneni, Ni Putu Gita Assyfa Ramadhina Ayucahyani, Anisya Septia Burhannuddin Claudia Marpaung Cokorda Dewi Widhya Hana Sundari Definingsih Yuliastuti Dela Rahmadani Desak Made Lestari Dewi Dewa Ayu Agustini Posmaningsih Dewi, Kadek Eliana Kesuma Dewi, Ni Km Ayu Kusuma Dewi, Ni Nyoman Astika Dewi, Ni Nyoman Astika Dwi Agustini, Desak Gede Fanani, Moch. Rizkhal Gejir, I Nyoman Gusti Ayu Marhaeni Guswita, Reni Handriyani, Kadek Ayu Tia Surya Hasana, Tasya Heri Setiyo Bekti I Gusti Agung Ayu Dharmawati I Gusti Ayu Sri Dhyanaputri I Nyoman Jirna, I Nyoman I Nyoman Purna I Wayan Jana I Wayan Karta I Wayan Karta I Wayan Mustika I Wayan Suardana Idazufina Idazufina Indrasari, Dewa Ayu Ratna Putri Kurniawan, Bayu Surya Kurniawan, Surya Bayu Kusumajaya, Anak Agung Ngurah Lely Ika Mariyati Leonel Hernandez, Leonel Lestari, renda Lisa Anjani, Ni Putu Lola Malihah Luh Ade Wilan Krisna Luh Ade Wilankrisna Manurung, Kiki Fatmalawati Mastra , Nyoman mastra, nyoman Maulia Asma Mayumi, Ni Kadek Sintya Merdekawati, Fusvita Mochamad Choirul Hadi Nadia Bismi Hafifah Nadilla Indriani Nasution Ni Nyoman Suindri Ni Wayan Rika Kumara Dewi Niluwih, Komang Deatriasa Pakerti Noviar, Ganjar Nugraheni, Clarissa Maheswari Setyo Laily Oktavia, Diana Posmaningsih, Dewa Ayu Agustini Pradnya Yasa, Ni Putu Candra Dewi Puji Aulia Rahmi Purnamasyah, Ika Putra, Anak Agung Ngurah Dwi Tisna Adi Putri Nadila Aswa Rahmadani, Najma Meutya Rakhmawati, Aprilia Ratih , Gusti Ayu Made Ratih, Gusti Ayu Made RIDHO KURNIAWAN, RIDHO Rinawati, Luh Putu Rindi, Oktavelendi Dhaneta Graha Ritonga, Dalilah Bazliah Rofi'ah, Lisa Khofidatur Savitri, Ni Putu Ayu Dani Shri Ayu Purnami Mahastuti Sopar Sri Anafarhanah, Sri SRI RAHAYU Subadra, Oemeria Shitta Suciati, Nabila Sudarmanto, I Gede Sudiantara, Ketut Sujaya, I Nyoman Suryaningsih, Putu Ayu Susila, Rismayanti Suyasa, I Nyoman Gede Suyasa, Ida Bagus Oka Swastini, I Gusti Agung Ayu Putu Usiono Usiono Vinenthy, Luh Putu Intan Visva Wilankrisna, Luh Ade Yudistia, Maghrisya Putri Zulham Siregar