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All Journal Buletin Ilmiah Nagari Membangun Oto Rhino Laryngologica Indonesiana Majalah Kedokteran Andalas JMB : Jurnal Manajemen dan Bisnis Indonesian Journal of Global Health research Jurnal Ilmu Kesehatan Indonesia (JIKSI) Community Services and Social Work Bulletin All Fields of Science Journal Liaison Academia and Sosiety Innovative: Journal Of Social Science Research Jurnal Kedokteran Hewan West Science Interdisciplinary Studies West Science Interdisciplinary Studies Jurnal Riset Ilmiah Jurnal Pengabdian Masyarakat Jurnal Sains, Teknologi dan Kesehatan Bioma : Jurnal Ilmiah Biologi
Adrial Adrial, Adrial
Fakultas Kedokteran Universitas Padang
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Gambaran Histopatologi Limpa Mencit (Mus Musculus Balb/C) yang Diinfeksi dengan Plasmodium Berghei Hendriani, Intania Dwiputri; Adrial, Adrial; Machmud, Rizanda; Hasmiwati; Yenita; Nita Afriani
Majalah Kedokteran Andalas Vol. 48 No. 1 (2025): MKA January 2025
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v48.i1.p37-45.2025

Abstract

Objective: to determine the histopathological picture of the spleen of mice (Mus musculus Balb/C) infected with Plasmodium berghei which has been immunized with An. sundaicus salivary gland extract. Method: This type of research is a descriptive study with a quantitative approach. This research was conducted at the Histology Laboratory of the Faculty of Medicine, Andalas University, from March 2023 to September 2024. Result: research on the histopathological picture of the spleen of mice Mus musculus Balb / C infected with Plasmodium berghei showed the number of spleen cell megakaryocytes in the control group with an average of 2.63 per field of view, in the pellet extract group 2.23 per field of view and in the supernatant extract group 2.13 per field of view. Conclusion: the average megakaryocyte cells in the spleen were the highest in mice injected with the control group and the average megakaryocyte cells in the spleen were the lowest in mice injected with the supernatant extract group.
Potential of Bioactive Compounds from Gambier (Uncaria Gambir Roxb.) in Modulating Cognitive Function: A Scoping Review Yusuf, Rahmi Novita; Adrial, Adrial; Desmawati, Desmawati; Lipoeto, Nur Indrawaty
Indonesian Journal of Global Health Research Vol 7 No 4 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i4.5936

Abstract

Aging is a process of diminishing tissue capacity for self-repair and maintenance of normal structure and function, leading to vulnerability to injury and damage. The high incidence of neurodegenerative diseases coincides with increased life expectancy in the elderly. An unavoidable negative effect of neurodegenerative diseases is the potential to cause cognitive decline. Gambier (Uncaria gambir Roxb.), containing 90% catechin, is a traditional plant with potential to enhance cognitive function. This scoping review aims to map existing research on the potential of bioactive compounds from gambier in modulating cognitive function, based on research articles in journals from the last 10 years in the PubMed, PMC, Google Scholar, and Google Scholar databases (2014-2024). The research was conducted by collecting research data from the last 10 years, totaling 12 articles. Among these, 4 articles met the inclusion criteria, focusing on the potential of bioactive compounds from gambier in modulating cognitive function. The article screening was conducted systematically using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) as 1 a guideline, followed by screening based on inclusion and exclusion criteria. This scoping review found potential for bioactive compounds from gambier in modulating cognitive function, as evidenced by increased Montreal Cognitive Assessment (MoCA) scores, decreased levels of Beta Amyloid (Aβ), Microtubule-Associated Protein Tau (MAPT), Malondialdehyde (MDA) levels, and increased Brain-Derived Neurotrophic Factor (BDNF). The potential of catechin, the primary bioactive compound in gambier, which possesses antioxidant, anti-inflammatory, and neuroprotective effects, yields beneficial results in enhancing cognitive function in the elderly.
Hubungan Pengetahuan dengan Tindakan Pencegahan terhadap Toksoplasmosis pada Mahasiswa Fakultas Kedokteran UNAND Swandi, Khairfani; Rusjdi, Selfi Renita; Burhan, Ida Rahmah; Adrial, Adrial; Irramah, Miftah; Fadila, Zurayya
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 1 (2024): Maret 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i1.1058

Abstract

Latar belakang: Toksoplasmosis merupakan penyakit asimtomatik yang tersebar di seluruh dunia. Sampai saat ini, Toksoplasmosis termasuk dalam kelompok Neglected Tropical Diseases (NTD’s). Seroprevalensi toksoplasmosis beberapa daerah di Indonesia tergolong cukup tinggi. Tingkat higienitas masyarakat di Indonesia juga tergolong rendah. Oleh karena itu, mahasiswa perlu memiliki pengetahuan dan tindakan pencegahan yang baik sebagai langkah awal untuk menurunkan risiko terinfeksi toksoplasmosis. Objektif: Mengetahui hubungan pengetahuan dengan tindakan pencegahan terhadap toksoplasmosis pada mahasiswa Fakultas Kedokteran Universitas Andalas. Metode: Penelitian ini merupakan penelitian model analitik cross sectional. Pengumpulan data dilakukan melalui kuesioner. Pemilihan sampel menggunakan metode stratified random sampling dari mahasiswa/I program studi Pendidikan Dokter Fakultas Kedokteran Universitas Andalas Angkatan 2019 dan 2020. Analisis data dilakukan dengan menggunakan uji chi-square Hasil: Hasil penelitian didapatkan bahwa 143 responden memiliki pengetahuan baik terkait toksoplasmosis dan 146 responden menerapkan tindak pencegahan yang baik terhadap toksoplasmosis. Kesimpulan: Kesimpulan yang didapatkan bahwa tidak terdapat hubungan antara pengetahuan dengan tindakan pencegahan terhadap toksoplasmosis pada mahasiswa Fakultas Kedokteran Universitas Andalas. Kata kunci: toksoplasmosis, Toksoplasma gondii, pengetahuan, tindak pencegahan
Gambaran Kelainan Refraksi di Poliklinik Mata RSUP Dr. M. Djamil Padang Tahun 2021 Dzulkifli, Dzulkifli; Hidayat, Muhammad; Liza, Rini Gusya; Vitresia, Havriza; Adrial, Adrial; Fadrian, Fadrian
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 1 (2024): Maret 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i1.1207

Abstract

Latar belakang: Kelainan refraksi merupakan tidak tepatnya cahaya jatuh di retina yang diakibatkan panjang aksial mata serta kekuatan optik yang terganggu. Ametropia adalah kondisi cahaya tidak dapat difokuskan di retina tanpa bantuan akomodasi karena adanya kelainan refraksi pada mata. Terdapat tiga jenis kelainan refraksi, yaitu miopia, hipermetropia, serta astigmatisme. Objektif: Tujuan penelitian ini adalah untuk mengetahui gambaran kelainan refraksi di Poli Mata RSUP Dr. M. Djamil Padang. Metode: Penelitian ini merupakan penelitian deskriptif observasional melalui studi kasus dengan mengumpulkan data rekam medis pasien kelainan refraksi di Poliklinik Mata RSUP Dr. M. Djamil Padang periode 1 Januari 2021 – 31 Desember 2021 dengan mata yang didiagnosis kelainan refraksi yang memenuhi kriteria inklusi dan ekslusi sebanyak 110 pasien. Seluruh variabel dianalisis dengan analisis univariat. Hasil: Hasil penelitian menunjukkan 85 pasien didiagnosis astigmatisme, dengan 50 pasien didiagnosis miopia, serta 8 pasien didiagnosis hipermetropia. Pasien kelainan refraksi dengan kelompok usia terbanyak adalah pada rentang 10-19 tahun (31.82%) dengan mayoritas perempuan (67.27%). Gejala klinis terbanyak adalah pandangan kabur (100%). Berdasarkan tingkatannya pasien miopia terbanyak adalah miopia tinggi (70.73%), hipermetropia terbanyak adalah hipermetropia rendah (76.92%), lalu astigmatisme miopia kompositus merupakan jenis astigmatisme terbanyak (83.01%). Visus pasien kelainan refraksi sebelum dan sesudah dikoreksi terbanyak adalah kelompok mild – no visual impairment (39.54%) & (94.09%). Kesimpulan: Gambaran dari pasien kelainan refraksi pada penelitian ini rentang usia 10-19 tahun merupakan kelompok usia terbanyak serta perempuan mengalami kelainan refraksi lebih banyak dari laki-laki. Dengan miopia derajat tinggi merupakan miopia terbanyak. Hipermetropia derajat rendah merupakan yang terbanyak. Serta astigmatisme miopia kompositus merupakan kelompok astigmatisme terbanyak. Keluhan umum terbanyak adalah pandangan kabur. Kategori visus terbanyak sebelum dan sesudah dikoreksi adalah kategori mild – no visual impairment. Kata kunci: miopia, hipermetropia, astigmatisme
PHYSIOLOGICAL RESPONSES OF FEMALE BEEF CATTLE AGAINST PEATLAND MICROCLIMATE STRESS IN CENTRAL KALIMANTAN Adrial, Adrial; Priyanto, Rudy; Salundik, Salundik; Yani, Ahmad; Abdullah, Luki
Jurnal Kedokteran Hewan Vol 17, No 2 (2023): June
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v17i2.29115

Abstract

This study aimed to evaluate the physiological response of female beef cattle to peatland microclimate stress in Central Kalimantan. This study used direct observation on small holder beef cattle farm. Microclimate data on 41 units cattle barns and physiological parameters of female cattle were collected in the morning, at noon and in the afternoon. The physiological parameter measurements involved 215 female beef cattle, consisting of 119 Bali and 96 crossbred cattle with different physiological stages including pregnant cows, lactating cows, dry cows, heifers and calves. The microclimate condition within cattle barns on peatland of Central Kalimantan is not the comfort zone for beef cattle. It is characterized by high air temperature and relative humidity, and low wind speed, which result in high temperature humidity index (THI). The barn with gable roof type and asbestos materials gave the lowest THI. This Microclimate caused heat stress to beef cattle reared on the peatlands, indicated by the high rectal temperature, heart rate, respiratory rate, and heat tolerance coefficient, although it was still categorized as mild to moderate stress. Bali cattle showed better physiological responses to microclimate stress than crossbred cattle. Pregnant crossbred cows were the most susceptible to peatland microclimate stress.
Hubungan Kejadian Infeksi Blastocystis sp dengan Profil Leukosit Darah Pada Penderita Kanker Kolorektal Zulmitra, Elsa; Nofita, Eka; Suchitra, Avit; Adrial, Adrial; Rofinda, Zelly Dia; Masnadi, Nice Rachmawati
Innovative: Journal Of Social Science Research Vol. 5 No. 3 (2025): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v5i3.19469

Abstract

Penelitian ini dilakukan dengan tujuan guna mengkaji hubungan hubungan antara infeksi Blastocystis sp dengan profil leukosit darah pada pasien yang menderita kanker kolorektal. Jumlah sampel yang digunakan sebanyak 22 sampel, yang dilaksanakan di RSUP Dr. M. Djamil Padang. Hasil Penelitian ini menyatakan bahwa dalam 22 pasien penyakit kanker kolorektal paling banyak ditemui pada lelaki dibandingkan wanita, dengan rata-rata umur 50,6 tahun. Sebesar 27,3% ditemukan pada pasien kanker kolorektal yang terkena infeksi Blastocystis sp. Rata-rata nilai leukosit pada pasien yang terkena infeksi Blastocystis sp pada penyakit kanker kolorektal sebanyak 9.792/mm3 dengan p value 0,9. Rata-rata jenis basofil / eosinophil / neutrofil / limfosit / monosit pada pasien yang terkena infeksi Blastocystis sp pada penyakit kanker kolorektal sebanyak 0/3/0/72/21/8, sedangkan pada pasien yang tidak terkena infeksi Blastocystis sp sebanyak 0/2/0/66/14/8 dengan p value lebih dari 0,05. Dengan demikian, hasil akhir dalam penelitian ini menyatakan bahwa tidak adanya hubungan antara infeksi Blastocystis sp dengan profil leukosit darah pada pasien yang menderita kanker kolorektal.
HUBUNGAN STATUS IMUNISASI BCG DENGAN MORTALITAS DAN DERAJAT SEVERITAS MENINGITIS TUBERKULOSIS ANAK DI RSUP DR. M. DJAMIL PADANG PERIODE 2018 – 2021 Nixon, Poety Elberta Husna; Lestari, Rahmi; Intan, Shinta Ayu; Amelin, Fitrisia; Ermayanti, Sabrina; Adrial, Adrial
SINERGI : Jurnal Riset Ilmiah Vol. 2 No. 6 (2025): SINERGI : Jurnal Riset Ilmiah, Juni 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v2i6.1314

Abstract

Objective: This study aims to determine the relationship between BCG immunization status with mortality and severity of TB meningitis in children at RSUP Dr. M. Djamil Padang. Method: This study used a cross-sectional design in children with TB meningitis and used the Kolmogorov-Smirnov and Chi-Square statistical tests. Sampling using total sampling technique with a total sample of 58 people. Data obtained from the medical records of RSUP Dr. M. Djamil Padang in 2018 – 2021. Result: This study shows that most pediatric TB meningitis patients with the condition are women (53%), aged 0-4 years (48%), good nutritional status (40%), not in direct contact with TB patients (74%), received BCG immunization (55%), severe degree (59%), and alive (76%). There is a relationship between BCG immunization status and degree of severity (p=0.046) and mortality (p=0.047) of pediatric TB meningitis patients at RSUP Dr. M. Djamil Padang in 2018 – 2021. Conclusion: The conclusion of this study is that there is a relationship between BCG immunization status and the degree of severity and mortality of TB meningitis in children at RSUP Dr. M. Djamil Padang in 2018 – 2021.
PENYULUHAN PENYAKIT INFEKSI KECACINGAN DAN GIARDIASIS TERHADAP ANAK BALITA STUNTING DI KELURAHAN KAMPUNG BARU NAN XX KECAMATAN LUBUK BEGALUNG KOTA PADANG Adrial, Adrial; Irawati, Nuzulia; Hasmiwati, Hasmiwati; Nurhayati, Nurhayati; Rusjdi, Selfi Renita; Nofita, Eka; Wardiyah, Husnil
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 7 No. 4 (2024)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v7i4.615

Abstract

Stunting is a condition of growth failure in toddlers due to chronic malnutrition and chronic infections, including worm infections and giardiasis. Kampung Baru Nan XX Village, Lubuk Begalung District, Padang City, is one of the areas with a high stunting rate. Education related to the prevention and treatment of this infectious disease is needed to improve public understanding in order to break the chain of causes of stunting. This counseling activity aims to improve public knowledge, especially mothers of toddlers, about the relationship between worm infections and giardiasis with stunting and preventive measures. The methods used are interactive lectures and discussions. The counseling involved mothers of toddlers and integrated health post cadres in the area. From the examination of 20 feces samples of toddlers in this area, no positive cases of worm infections and giardiasis were found. The results of this activity showed a good understanding of the participants regarding the importance of environmental sanitation, personal hygiene, and providing nutritious food to children. This counseling is effective in increasing public awareness regarding worm infections and giardiasis as risk factors for stunting. Follow-up activities can be carried out in the form of monitoring and providing nutritional interventions to support sustainable stunting prevention in this region.
Gambaran kasus epistaksis di IGD RSUP Dr. M. Djamil Padang periode 2018-2022 Irfandy, Dolly; Adrial, Adrial; Sariwati, Siska; Asyari, Ade; Nofita, Eka; Anggraini, Fika Tri
Oto Rhino Laryngologica Indonesiana Vol. 54 No. 2 (2024): VOLUME 54, NO. 2 JULY - DECEMBER 2024
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v54i2.675

Abstract

Background: Epistaxis is a common case that occurs in Ear Nose Throat (ENT) Department. Epistaxis can be managed independently, but mortality and morbidity rates will increase if it occurs in children, elderly, and patient with systemic conditions. Purpose: To understand epistaxis in terms of patient age, gender, risk factor, bleeding location, treatment, and age distribution based on etiology and risk factors. Method: A descriptive retrospective study, using secondary data from medical records of patients with chief complaints of epistaxis at the emergency installation of Dr. M. Djamil General Hospital in Padang, from 2018 to 2022. Result: The study found 329 patients who came with chief complaints of epistaxis. Epistaxis mostly found at age above 45 years old. Most cases happen in males (64.1%). The most common etiology and risk factors found were hypertension (21.4%). Most frequent bleeding location found in the anterior part (80.5%). Most epistaxis patients were treated with nasal compression (26.4%). The most common causes of epistaxis in children were mechanical trauma, in young adults fractures of the maxillofacial region, and hypertension in elderly. Conclusion: Epistaxis can occur in all age groups and can occur spontaneously or accompanying a disease. The etiology and risk factors of epistaxis vary based on age groups. Epistaxis is treated according to the cause. Keywords: epistaxis, age, risk factors, treatment   ABSTRAK Latar belakang: Epistaksis merupakan kasus yang sering terjadi di bagian THT. Epistaksis dapat ditangani secara mandiri, namun angka mortalitas dan morbiditas akan meningkat jika terjadi pada anak-anak, lansia, dan pasien dengan kondisi sistemik. Tujuan: Untuk mengetahui gambaran epistaksis ditinjau dari usia pasien, jenis kelamin, faktor risiko, lokasi perdarahan, penanganan, dan distribusi usia berdasarkan etiologi dan faktor risiko. Metode: Studi deskriptif retrospektif dengan menggunakan data sekunder dari rekam medis pasien dengan keluhan utama epistaksis di Instalasi Gawat Darurat RSUP Dr. M. Djamil di Padang, dari 2018-2022. Hasil: Penelitian menemukan 329 pasien yang datang dengan keluhan utama epistaksis. Epistaksis paling banyak ditemukan pada usia di atas 45 tahun. Sebagian besar kasus terjadi pada laki-laki (64,1%). Etiologi dan faktor risiko yang paling banyak ditemukan adalah hipertensi (21,4%). Lokasi perdarahan yang paling sering ditemukan di bagian anterior (80,5%). Sebagian besar pasien epistaksis ditangani dengan kompresi hidung (26,4%). Penyebab epistaksis yang paling sering ditemukan pada anak-anak adalah trauma mekanik, pada dewasa muda fraktur pada daerah maksilofasial, dan hipertensi pada lansia. Kesimpulan: Epistaksis dapat terjadi pada semua kelompok usia dan dapat terjadi secara spontan atau menyertai suatu penyakit. Etiologi dan faktor risiko epistaksis bervariasi berdasarkan kelompok usia. Penatalaksanaan epistaksis dilakukan sesuai dengan penyebabnya. Overview of epistaxis cases in emergency installation. Kata kunci: epistaksis, usia, faktor risiko, tatalaksana
The Role of Transportation Accessibility and Public Facilities on Tourism Experience in Tourist Destinations in Central Java Adrial, Adrial; Sulistiyono, Arief; Khazinatul Khaeriah, RD. Hera Merdeka
West Science Interdisciplinary Studies Vol. 4 No. 01 (2026): West Science Interdisciplinary Studies
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/wsis.v4i01.2595

Abstract

This study investigates the influence of transportation accessibility and public facilities on the tourist experience in tourist destinations in Central Java, Indonesia. A quantitative research approach was employed using survey data collected from 200 tourists. The research instrument was a structured questionnaire measured using a five-point Likert scale. Transportation accessibility and public facilities were examined as independent variables, while tourist experience served as the dependent variable. Data analysis was conducted using the Statistical Package for the Social Sciences (SPSS) version 25, applying descriptive analysis, validity and reliability tests, and multiple linear regression analysis. The results indicate that transportation accessibility has a positive and significant effect on tourist experience, demonstrating that ease of access, transportation availability, and connectivity contribute substantially to tourists’ overall perceptions. Public facilities also show a positive and significant effect, highlighting the importance of adequate amenities such as sanitation, parking, signage, and information services in enhancing comfort and satisfaction. Furthermore, both variables simultaneously explain a substantial proportion of the variance in tourist experience. These findings underline the importance of integrated transportation systems and well-maintained public facilities in improving tourist experience and strengthening destination competitiveness in Central Java.
Co-Authors Abdul Rohim, Abdul Ade Asyari ahmad yani Aliya, Lisana Shidiqqin Amelin, Fitrisia Ananda, Abi Awfa Rahman Desmawati Desmawati Dian Pertiwi Dolly Irfandy Dzulkifli, Dzulkifli Elmatris Sy Endrinaldi , Endrinaldi Ermayanti, Sabrina Fadila, Zurayya Fadita, Puteri Ayudia Fadrian, Fadrian Fika Tri Anggraini Hanggara, Muhammad Azzel Hanum, Fathiya Juwita Hasibuan, Imron Martua Hasmiwati Hendriani, Intania Dwiputri Husnil Wardiyah Ida Rahmah Burhan Intan, Shinta Ayu Jamsari Jamsari Julizar Julizar Kartini, Raden Asri Khazinatul Khaeriah, Rd. Hera Merdeka Lestari, Rahmi Lily Syukriani Luki Abdullah Masnadi, Nice Rachmawati Miftah Irramah Mubarok, Khairil Muhammad Hidayat Netti Suharti, Netti Nita Afriani Nixon, Poety Elberta Husna Nur Indrawaty Lipoeto Nuranissa, Dinda Widy Nurhayati Nurhayati Nursyafi, Fauzan Syarif Nuzulia Irawati Prameswary, Canticha Aulia Rini Gusya Liza, Rini Gusya Rizanda Machmud Rudy Priyanto Salundik Sariwati, Siska Selfi Renita Rusjdi Suchitra, Avit Sulistiyono, Arief Swandi, Khairfani Utami Mayfa Rahmania Vitresia, Havriza Yaslinda Yaunin Yenita . Yulistini, Yulistini Yuniar Lestari Yustini Alioes yusuf, rahmi novita Zelly Dia Rofinda Zulmitra, Elsa