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All Journal Jurnal Kedokteran Syiah Kuala Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Althea Medical Journal Jurnal Berkala Epidemiologi Berkala Ilmu Kesehatan Kulit dan Kelamin Folia Medica Indonesiana Jurnal NERS Indonesian Journal of Tropical and Infectious Disease Jurnal Media Gizi Indonesia (MGI) The Indonesian Biomedical Journal Science and Technology Indonesia Journal Of Vocational Health Studies Amerta Nutrition JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Jurnal Pengabdian Masyarakat dalam Kesehatan Indian Journal of Forensic Medicine & Toxicology Medicosphere Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)

Erwin Astha Triyono

Department Of Internal Medicine, Faculty Of Medicine, Universitas Airlangga, Surabaya, Indonesia

Author-ID : 508768

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Earth & Planetary Sciences Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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PROTEIN 24 HIV DAN LIMFOSIT T-CD4+ DI INFEKSI HIV TAHAP I (HIV p24 Protein and CD4+ T-lymphocyte in Stage I HIV infection) I Made Sila Darmana; Endang Retnowati; Erwin Astha Triyono
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 21, No 3 (2015)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v21i3.1280

Measuring HIV p24 protein is a test which is more practical than determination of CD4+ T-lymphocyte counts and viral load, asit does not require a very sophisticated instrument and requires a lower cost. Independent predictive value of p24 to the decline ofCD4+ T-lymphocytes, clinical progression and survival in HIV-infected patients have been reported. In this study, HIV-infected patientswere found to have HIV p24 protein levels inversely proportional to CD4+ T-lymphocyte counts by using Spearman test (R2=0.225;p=0.0331). Studies on the correlation between HIV p24 protein levels and CD4+ T-lymphocyte counts in stage I HIV infection have notyet been reported. The aim of this study was to prove the correlation between HIV p24 protein levels and CD4+ T-lymphocytes in stageI HIV infection. Research issue was whether a correlation between HIV p24 protein levels and CD4+ T-lymphocyte counts in stage I HIVinfection existed ? The hypothesis was that a correlation between HIV p24 protein levels and CD4+ T-lymphocyte counts in stage I HIVinfection existed. The study design was cross sectional observational. Subjects consisted of 30 stage I HIV-infected patients treated at theInfectious Disease Intermediate Care Unit, Dr. Soetomo Hospital and VCT Clinic of the Dr. Ramelan Naval Hospital, Surabaya from Mayto July 2014. Stage I HIV infection is an asymptomatic HIV infection or with persistent generalized lymphadenopathy and the patientis able to perform normal activities. Levels of p24 were measured by ELISA method and CD4+ T-lymphocyte counts using flowcytometry(BD FACSCaliburTM). The results were statistically analyzed using Pearson’s correlation test. HIV p24 protein levels in stage I of HIVinfection ranged from 1.8 to 10.8 pg/mL, mean of 5.14 pg/mL and a standard deviation of 2.08 pg/mL. CD4+ T-lymphocyte countsdecreased with a range of 49-559 cells /uL for absolute values and 4.42–26.02% for percentage values Correlations between blood p24levels and CD4+ T-lymphocyte counts either absolute (r=–0.392, p=0.032) or percentage (r=–0.363, p=0.049) were found. In stageI HIV-infected patients, a negative correlation was found between p24 levels and CD4+ T-lymphocyte counts, in both CD4+T-lymphocytecounts as absolute and as well as percentage values. This negative correlation showed that the p24 HIV levels were inversely proportionalto the CD4+ T-lymphocyte counts. HIV p24 protein levels have a possibility to be used predicting CD4+ T-lymphocyte counts.

Diagnostic Patterns of Suspected Covid-19 Patients Using Scor Covid-19, PCR Test and Serological Test in Dr. Soetomo Hospital Surabaya, Indonesia Usman Hadi; Bramantono Bramantono; M Vitanata; Musofa Rusli; Brian Eka Rahman; Tripudi Asmarawati; Erika Marfiani; Erwin Astha Triyono
Current Internal Medicine Research and Practice Surabaya Journal Vol. 2 No. 2 (2021): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v2i2.28956

Objective: To find out the diagnostic pattern of COVID-19 using RT-PCR or a rapid antibody test in the suspected group of patients.Method: The study was conducted in Dr. Soetomo General Hospital (referral hospital for covid-19, 1500 beds). The study used data on patients with suspected covid-19 who were hospitalized at the Dr. Soetomo General Hospital in Surabaya.Result: There were 200 suspected COVID-19 patients enrolled in this study, the main complaints of cough, fever, dyspnoea, around 69.5%, 75%, and 76.5%, respectively. Although not a common symptom, it seems that anosmia (14%) is typical for COVID-19. Based on this scoring system, a total of 196 patients had a high risk of being infected with COVID-19, and 125 (64%) of them finally showed a positive PCR test. PCR test mostly positive (62.5%), while serological test (rapid immunoglobulin test) mostly nonreactive, but there were no significant differences between PCR and Serological test (p=0.16 OR: 1.5(0.84-71). Furthermore, if we compare the various existing variables, namely the covid-19 score, immunoglobulin rapid test, and radiological examination, only the radiological examination results can be used as a strong predictor of positive PCR results (p=0.005, OR: 1.68 (0.17-16.43).In this study, we found that abnormal chest radiographs are a good parameter for diagnosing COVID-19, (OR: 2.92; 95% CI, 1.34 -6.34).Conclusion: The initial radiological examination combined with the clinical symptoms of Covid-19 is the most important thing to predict the presence of this disease.

ORGANIZING COVID-19 SURVIVORS AS CONVALESCENT PLASMA DONORS Erwin Astha Triyono; Rimbun Rimbun
Jurnal Pengabdian Masyarakat Dalam Kesehatan Vol. 4 No. 1 (2022): APRIL 2022
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar

Introduction: Convalescent plasma transfusion therapy remains as one of the therapies recommended by the Ministry of Health for Covid-19 patients in Indonesia. However, in its practice, this therapy is greatly constrained by the availability of plasma donors at the Indonesian Red Cross (PMI) and the few survivors who are willing to donate their blood plasma. The aims of the community service activity were to educate, organize, and facilitate the survivors to do screening and donate their plasma. Methods: The activities were conducted in June until December 2021, at Indrapura Field Hospital (RSLI) Surabaya. A total 925 participants (641 male and 309 female) were all Covid-19 patients from RSLI Surabaya. The demographic data were collected and organized as a database. The survivor's online communication group (16 WhatsApp groups) were created, to provide information and education about Covid-19 and the importance of plasma donation to the patients and survivors. Results: The three largest groups by age were 26-35 (30.84%), 46-55 (21.26%), and 36-45 (19.47%) years old. The 3 largest groups by city of origin were Surabaya (62.42%), Sidoarjo (16.53%), and Gresik (8.63%). About 77.89% of participants have their understanding in the convalescent plasma for Covid-19. About 43.79% of them were willing to become donors after 14-day-recovery, and have been registered in the web application of donors. The 102 survivors were also involved in free plasma screening with PMI Surabaya. Total 88 survivors who have passed the screening have given their plasma as convalescent donors. Conclusion: Organizing and educating Covid-19 survivors were exceptionally required to encourage them to become a plasma donor. The collected survivor data must be stored and managed properly to facilitate everything related to the blood plasma. The survivors are suggested to be screened 14 days after being declared healthy, to maintain the availability of blood plasma at PMI for Covid-19 patients who necessitate the convalescent plasma therapy.

Hubungan Kepatuhan Minum Obat Anti Diabetik dengan Regulasi Kadar Gula Darah pada Pasien Perempuan Diabetes Mellitus Oryza Dwi Nanda; Bambang Wiryanto; Erwin Astha Triyono
Amerta Nutrition Vol. 2 No. 4 (2018): AMERTA NUTRITION
Publisher : Universitas Airlangga, Kampus C, Mulyorejo, Surabaya-60115, East Java, Indonesia

Background: Blood glucose level controlling is the important thing for diabetes mellitus treatment. Diabetics patients need to understand the factors which influence blood glucose level such as the compliance of anti-diabetic drug.Objective: Determine the relationship and the risk of between oral anti-diabetic drug consumption adherence and blood glucose level regulation for diabetes mellitus female patients.Method: Case control study design with purposive sampling technique, in order to obtain 26 research samples which consist of two groups, they are case group (unregulated blood glucose) which has 13 samples and the control group (regulated blood glucose) whice has 13 samples. The samples are female respondents aged 45-59 years old suffering diabetes mellitus. This research analyzed the relationshipand risk between anti-diabetic consumption adherence and blood glucose level regulation in diabetes mellitus patients using chi-square test.Results: Patients with unregulated blood glucose showed 46.2% people were obedient and 53.8% were not obedient in consuming anti-diabetic drugs. Patients with regulated blood glucose showed 92.3% people were obedient and 7.7% people were not obedient in consuming anti-diabetic drugs. Chi square test showed that there was a relationship between anti-diabetic drugs consumption adherence and blood glucose level regulstion for diabetes mellitus patients with p = 0.015 (p <0.05) and an OR value of 14 with a 95% CI (1.385-141.485), which means that unobedient have 14 times risker suffered terrible blood glucose regulation than obedient patients.Conclusion: There was a relationship between anti-diabetic drug consumption adherence and blood glucose level regulation in female patients aged 45-59 years in Mojo Health Center, Pucang Sawu, and Keputih Surabaya. Patients with uncontrolled blood sugar level are more disobedient in consuming anti-diabetic drugs. Meanwhile, patients with controlled blood glucose were most obedient people in consuming anti-diabetic drugs.ABSTRAKLatar Belakang: Pengendalian kadar gula darah merupakan hal yang penting dalam penanganan diabetes melitus. Pasien diabetes perlu memahami faktor-faktor yang mempengaruhi pengendalian kadar gula darah salah satunya adalah kepatuhan minum obat anti diabetik.Tujuan: Mengetahui hubungan dan besar risiko kepatuhan minum obat oral anti diabetik dengan regulasi kadar gula darah pada pasien perempuan diabetes mellitus.Metode: Desain penelitian kasus kontrol dengan teknik purposive sampling, sehingga diperoleh 26 sampel penelitian yang terdiri dari dua kelompok yaitu kelompok kasus (gula darah tidak teregulasi) sebanyak 13 dan kelompok kontrol (gula darah teregulasi) sebanyak 13 responden perempuan berusia 45-59 tahun yang menderita diabetes melitus. Hubungan dan besar risiko kepatuhan minum obat anti diabetik dengan regulasi gula darah pasien diabetes mellitus menggunakan uji chi-square. Hasil: Pasien dengan gula darah tidak teregulasi menunjukkan sebanyak 46,2% patuh dan 53,8% tidak patuh dalam minum obat anti diabetik. Pasien dengan gula darah teregulasi menunjukkan sebanyak 92,3% patuh dan 7,7% tidak patuh dalam minum obat anti diabetik. Uji chi square menunjukkan terdapat hubungan antara kepatuhan minum obat anti diabetik dengan regulasi kadar gula darah pada pasien diabetes melitus dengan nilai p=0,015 dan nilai OR sebesar 14 dengan CI 95% (1,385-141,485) yang berarti responden yang tidak patuh minum obat anti diabetik berisiko 14 kali mengalami regulasi gula darah yang buruk dibandingkan dengan pasien yang patuh dalam minum obat anti diabetik.Kesimpulan: Terdapat hubungan antara kepatuhan minum obat anti diabetik dengan regulasi gula darah pada pasien perempuan rawat jalan usia 45-59 tahun di Puskesmas Mojo, Pucang Sawu, dan Keputih Surabaya. Pasien dengan kadar gula darah tidak terkontrol lebih banyak tidak patuh dalam minum obat anti diabetik, sedangkan pada pasien dengan gula darah terkontrol sebagian besar cukup patuh dalam minum obat anti diabetik.

Asupan Vitamin A, C, E, Dan IMT (Indeks Massa Tubuh) Pada Lansia Hipertensi dan Non Hipertensi Di Puskesmas Banyu Urip, Surabaya Intan Putri Risky Amalia; Erwin Astha Triyono
Amerta Nutrition Vol. 2 No. 4 (2018): AMERTA NUTRITION
Publisher : Universitas Airlangga, Kampus C, Mulyorejo, Surabaya-60115, East Java, Indonesia

Background: Hypertension is a non-comunicable disease that easy found in ederly. Dietary intake had an important role as prevent and manage hypertension.Objectives: The objective of this study was to invistigate correlation of dietary intake of vitamins A, C, E and Body Mass Index (BMI) with hypertension among ederly at Puskesmas Banyu Urip Surabaya.Methods: This study was observational that uses case-control desain. Samples calculated according Lemeshow formula amount of 32 respondent (total case and control). This study was held in July until August 2018. Statistical analysis use Chi Square.Results: The result showed that most of subjects were 66-70 years old, woman (87.5%), who had education history primary school (37.5%), and work as house wife (71.9%). Most of subject had adequate vitamin A (96.9%), inadequate vitamin C (87.5%) and inadequate vitamin E (100%). BMI most subject was normal (59.4%). This study demostrated that there was no significant correlation between vitamin C intake and hypertension (OR=3.462; 95% CI=0.32-37.473; p=0.300), and no significant correlation between BMI and hypertension (OR=0.455; 95% CI=0.18-1.921; p=0.236). Averange intake of vitamin A in respondent hypertension was 1301.02±407.84 ug and 1968.03 ±407.84 ug in respondent with normo tension. Averange intake of vitamin E in respondent hypertension was 3.06 ±1.2 mg and 3.34 ±1.23 mg in respondent with normo tension. Conclusions: There was no significant correlation between dietary intake vitamin C and BMI with hypertension. Averange intake of vitamin A, C, and E was better in respondent with normo tension. ABSTRAKLatar Belakang: Hipertensi merupakan penyakit tidak menular dan mudah ditemui pada usia lansia. Asupan makanan memegang peranan penting dalam mencegah dan penatalaksanaan hipertensi.Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan antara asupan vitamin A, C, E dan IMT dengan hipertensi pada lansia di Puskesmas Banyu Urip Surabaya.Metode: Penelitian ini menggunakan metode observasional dengan desain case control. Sampel penelitian ini dihitung sesuai dengan rumus Lemeshow yakni sebesar 32 responden (total kelompok kasus dan kontrol). Penelitian ini dilakukan pada bulan Juli hingga bulan Agustus 2018. Analisis statistik yang digunakan uji Chi Square.Hasil: Sebagian besar responden berusia 66-70 tahun, berjenis kelamin wanita (87,5%), riwayat pendidikan terakir SD sederajat (37,5%), dan berkerja sebagai ibu rumah tangga (71,9%). Tingkat kecukupan vitamin A sebagian besar baik (96,9%). Tingkat kecukupan vitamin C sebagian besar kurang (87,5%). Tingkat kecukupan vitamin E kurang (100%). IMT sebagian besar responden normal (59,4%). Tidak terdapat hubungan yang signifikan antara asupan vitamin C dengan hipertensi (OR=3,462; 95% CI=0,32-37,473; p=0,300) dan tidak terdapat hubungan yang signifikan IMT dengan hipertensi (OR=0,455; 95% CI=0,18-1,921; p=0,236). Rata-rata asupan vitamin A pada responden hipertensi sebesar 1301,02 ±407,84 ug dan pada tekanan darah normal 1968,03 ±956,67 ug. Rata-rata asupan vitamin E pada responden hipertensi sebesar 3,06 ±1,2 mg dan pada tekanan darah normal sebesar 3,34 ±1,23 mg.Kesimpulan: Asupan vitamin C dan IMT tidak berhubungan signifikan dengan kejadian hipertensi. Rata-rata asupan vitamin A, C, dan E lebih besar pada responden kelompok tekanan darah normal.

Determination of (+)-Catechin and Antioxidant Activity in Faloak (Sterculia quadrifida R. Br) Stem Bark Infusion Audrey Gracelia Riwu; Jusak Nugraha; Djoko Agus Purwanto; Erwin Astha Triyono
Science and Technology Indonesia Vol. 8 No. 1 (2023): January
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2023.8.1.59-65

Oxidative stress is a condition that can damage human cells and tissues and has been linked to a number of illnesses, including cancer, cardiovascular disease, autoimmune disorders, and neurological diseases. Oxidative stress conditions can be brought on by pollution, radiation exposure, and an unhealthy lifestyle. Antioxidants are substances that can be used to both prevent and treat oxidative stress. This study aimed to identify and quantify (+)-catechin levels and antioxidant activity of the stem bark of Sterculia quadrifida R. Br extracted by the infusion method, a method similar to traditional medicine processing generally in the community. Determination of (+)-catechin and antioxidant activity of S. quadrifida were evaluated by HPLC and DPPH assay, respectively. Quantification of (+) catechin content by HPLC system with wavelength 280 nm and antioxidant activity by spectrophotometry method with wavelength 517 nm. The results show that the mean value of (+)-catechin level was 7.786% and the IC50 value of the antioxidant activity was 51.5 ug/mL having a moderate antioxidant activity category. S. quadrifida stem bark infusion can be utilized as a medication candidate for the prevention or treatment of a variety of disorders caused by oxidative stress.

Clinical Profiles and Il-6 Level Analysis of Critical Covid-19 Patients Receiving Lopinavir-Ritonavir Erwin Astha Triyono; Nancy Margarita Rehatta; Nabilah; Feriawan Tan
Folia Medica Indonesiana Vol. 59 No. 2 (2023): June
Publisher : Universitas Airlangga

Highlights:1. Lymphocyte, procalcitonin, D-dimer and high IL-6 levels in COVID-19 patients are associated with a poor prognosis.2. IL-6 serial measurement for COVID-19 patients may be a potential indicator for evaluating the severity and patient outcome. Abstract The COVID-19 pandemic has affected over 760 million individuals worldwide, resulting in more than 6.8 million reported deaths. Early detection of patient deterioration can assist in predicting outcomes and prioritizing healthcare services based on evidence-based indicators. Interleukin-6 (IL-6) is a cytokine that plays a role in the inflammatory process, making it a potential parameter for assessing a patient's inflammatory state. This study aimed to analyze the characteristics, laboratory profiles, and IL-6 levels of COVID-19 patients. This study used a retrospective cohort study design with medical record data. The characteristics (n=68) and IL-6 levels (n=52) of the patients on the first, third, and sixth days of treatment were recorded consecutively. The mean age of the patients was 49 years, with the majority being male (72%) and the most prevalent comorbidity being hypertension (29%). The average duration of hospitalization was 10.94 days. Shortness of breath was the most commonly reported symptom (45.6%). The medians of neutrophil-lymphocyte ratio, C-reactive protein, procalcitonin, ferritin, and D-dimer were above normal. Significant differences were observed in lymphocytes (p=0.046), procalcitonin (p=0.023), and D-dimer (p=0.000) between survivor and non-survivor patients. Significant dynamic changes in IL-6 levels were observed from the first day to the sixth day (p=0.014) and from the third day to the sixth day (p=0.041). In conclusion, risk stratification, laboratory profiles, and IL-6 levels play a role in assessing the severity and outcomes of COVID-19 patients.

CORRELATION BETWEEN INTERFERON GAMMA RELEASE ASSAY OF ELISPOT METHOD AND CD4+ T LYMPHOCYTE CELL COUNT IN HIV POSITIVE PATIENTS Nabil Salim Ambar; Aryati Aryati; Tutik Kusmiati; Erwin Astha Triyono
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 25 No. 3 (2019)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v25i3.1416

HIV is a virus that can cause AIDS, which affects the immune system and weakens the body function in fighting disease. The primary cells that HIV attacks are CD4+ T lymphocytes. Opportunistic Infections (OIs) are the biggest risk factors of death in HIV patients and occur in CD4+ T cells <200 cells/Î¼L lymphocytes. TB is a disease with a high mortality rate in the world where Indonesia is a TB endemic country with the highest morbidity rates of TB in the world. The most common OI in people with HIV is TB. The number of limitations on Tuberculin Skin Test (TST) is large, thus in vitro T cells test with (Interferon Gamma Release Assay) IGRA is used in diagnosing latent TB. The aim of this study was to determine the correlation between IGRA ELISPOT method and CD4+ T lymphocyte cell count in HIV positive patients. This was an observational analytical study with cross sectional design. The number of samples was 56 HIV positive patients who were treated at the UPIPI Clinic of the Dr Soetomo Surabaya Hospital. The examination of CD4+ T lymphocyte count was perfomed with FACSCalibur and IGRA was examined with T-SPOT.TB. The results were analyzed using Spearman correlation test. CD4 + lymphocyte cell counts based on WHO groupings were as follows: > 500 cells / Î¼L (33.92%), 200-349 cells / Î¼L (25%), 350-499 cells / Î¼L (25%) and <200 cells / Î¼L (16 , 07%). IGRA examination results showed 35.18% positive and 64.81% negative. The grouping of CD4+ T lymphocyte cell counts based on IGRA test results was 27.77% with positive IGRA and 48.14% with negative IGRA. Spearman correlation test between CD4+ T cell lymphocytes with IGRA in HIV positive patients showed r = 0,036 (p = 0,794). There was no correlation between interferon gamma release assay of ELISPOT method and CD4+ T lymphocyte cell count in HIV positive patients.

EARLY DETECTION OF TUBERCULOSIS APPLICATION (E-TIBI): A NEW PARADIGM TO DETECT NEW CASE OF TUBERCULOSIS: Aplikasi Deteksi Dini Tuberkulosis (E-TIBI): Paradigma Baru untuk Menemukan Kasus Baru Tuberkulosis Erwin Astha Triyono; MVS Mahanani; Sulvy Dwi Anggraini; Hafidh Maulana; Wahyu Dian Pratiwi; Christian Yochanan; Feriawan Tan; Lilis Masyfufah
Jurnal Berkala Epidemiologi Vol. 11 No. 3 (2023): Jurnal Berkala Epidemiologi (Periodic Epidemiology Journal)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbe.V11I32023.267-276

Background: Tuberculosis (TB) is still one of the major health problems in the world, especially in countries with dense populations. Indonesia is listed among the top three countries with the highest burden of tuberculosis worldwide. The low coverage of case detection in Indonesia is one of the reasons for ineffective TB control. Therefore, this disease remains a threat to spread in today's Indonesian society. Digital technology can be used to increase the effectiveness and efficiency of case detection. This study aims to create a new paradigm for detecting new cases of tuberculosis using a self-assessment website-based application. Methods: This descriptive quantitative research used univariate analysis. Respondents for this research were sampled from all East Java people who filled out the E-TIBI application. Result: In total, there were 4,658 E-TIBI users in East Java, with 20.80% suspected of tuberculosis. The most frequent symptoms found in the respondents were fatigue, cough for > 2 weeks, and weight loss. Discussion: A self-assessment paradigm based on digital technology was applied to the design of this E-TIBI application. From this application, the public can quickly determine whether they or others are suspected of having tuberculosis. This result shows that the whole community can easily access the E-TIBI application for initial tuberculosis screening. Conclusion: Through this application, direct community participation can increase the detection of new cases to support the government and WHO programs in eliminating tuberculosis by 2030.

Body mass index as the main predictor for length of stay in COVID-19 patients with mild and moderate symptoms: a cross-sectional study in COVID-19 emergency hospital in Indonesia Siti Rahayu Nadhiroh; Anisa Lailatul Fitria; Armedy Ronny Hasugian; Erwin Astha Triyono; Nono Tri Nugroho; Alfadhila Khairil Sinatrya; Hazreen B Abdul Majid
Jurnal Ners Vol. 19 No. 2 (2024): MAY 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jn.v19i2.53973

Introduction: COVID-19 emerged as a novel global health crisis. While it has since been downgraded from its status as a public health emergency of international concern, the virus persists as a global health challenge. This study was aimed to analyze the predictors of LoS in COVID-19 patients based on nutritional status and patient characteristics data. Methods: Participants of this study were the COVID-19 patients with mild to moderate symptoms who registered in COVID-19 Emergency Hospital, East Java, Indonesia. This study involved 2850 patients extracted from medical records for further analysis. Body mass index (BMI) was generated following the standard formula measured on the first day of hospitalization. LoS was determined by the number of days of hospitalization. The Chi-square automatic interaction detection (CHAID) algorithm was employed for model building. Results: Most participants were overweight (34.6%) and obese (17.2%). Only a few participants were hospitalized with comorbidities such as hypertension (11.6%) and diabetes mellitus (4.1%). The predictive model of LoS indicated that BMI was the main predictor of COVID-19 LoS, with higher BMI showed to prolong the LoS of mild to moderate symptoms patients. Other than BMI, gender and symptoms were also indicated as COVID-19 LoS predictors. Conclusions: Nutritional status is one of the predictors of LoS in COVID-19 patients. Having higher BMI tends to prolong the LoS, especially in male and having fever. LOS was also seen among those with lower BMI less than 18.5, in patients who had cold and flu.

Co-Authors Afif Nurul Hidayati Alfadhila Khairil Sinatrya Amos Pongbulaan Anak Agung Ayu Niti Wedayani Anindita Abigail Anisa Lailatul Fitria Aprilawati, Dwi Arini, Merita Armedy Ronny Hasugian Aryati Aryati Aryati Aryati Aryati Audrey Gracelia Riwu Bambang Wiryanto Bramantono Bramantono, Bramantono Brian Eka Rahman Budiono Budiono Christian Yochanan Christina Avanti Cita Rosita Sigit Prakoeswa Djoko Agus Purwanto Djoni Susanto Dwi Murtiastutik Eddy Bagus Wasito Endang Retnowati Endang Retnowati Endang Wahyu Fitriani Erika Marfiani Erna Kristin Eti Nurwening Sholikhah Eva Lydiawati Faiz Murfid Gunawan Feriawan Tan Firdausa, Sarah Firdausiyah Firdausiyah Hafidh Maulana Harianah Harianah Hazreen B Abdul Majid Hermi Indita I Made Sila Darmana Intan Putri Risky Amalia Iskandar Zulkarnain Ivan Hoesada James Hutagalung Jaya, Halim Priyahau JS. Hutagalung Jusak Nugraha Kartikadewi, Indriani Kartikawati, Tri Kartina, Leny kawilarang, Arthur pohan Kusmiati, Tutik Kusumayanti, A.A.Ayu Mas Linda Astari, Linda M Vitanata M. Yulianto Listiawan Mahdian, Haidar Masyfufah, Lilis Muhammad Amin Musofa Rusli MVS Mahanani Nabil Salim Ambar Nabilah Nono Tri Nugroho Noor Idha Handajani Novanda, Aisyah Wahyu Nurohmawati, Weni Oryza Dwi Nanda Pambudi, Rien Esti Pauline Hadisiswoyo Pudji Lestari R. Heru Prasetyo R. Heru Prasetyo Rachmad, Eka Basuki Rahmadewi Rahmadewi Ramadhani, Putri Nabilah Rehatta, Nancy Margarita Rimbun Rimbun Rohiman, Abu Senda Sulvain Rahmaningrat Shinta Karina Yuniati Siti Rahayu Nadhiroh Siti Surdijati, Siti Sulistiawati Sulistiawati Sulvy Dwi Anggraini Syahru Ramadhaan Unzila Tan, Feriawan Tripudi Asmarawati Umiastuti, Pirlina Usman Hadi Usman Hadi Wahyu Dian Pratiwi Wahyunitisari, Manik Retno Widjaja, Sajuni

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