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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. Jurnal Kedokteran Brawijaya Biology, Medicine, & Natural Product Chemistry Biomedika Bioeksperimen: Jurnal Penelitian Biologi Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Jurnal Kedokteran dan Kesehatan Herb-Medicine Journal Indonesian Journal of Medicine PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Litbang Sukowati : Media Penelitian dan Pengembangan Cermin Dunia Kedokteran Proceeding ISETH (International Summit on Science, Technology, and Humanity) Prosiding University Research Colloquium Jurnal Pengabdian Masyarakat Medika
Safari Wahyu Jatmiko
Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Correlation of Mean Corpuscular Hemoglobin, Mean Corpuscular Hemoglobin Concentration and Platelet to Hemoglobin Ratio with the Degree of Dengue Virus Infection in Pediatric Patients Alim, Fika Nurul; Jatmiko, Safari Wahyu; Puspitasari, Metana
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5511

Abstract

Purpose: This study aimed to evaluate the correlation between MCH, MCHC, and PHR with the severity of DVI in pediatric patients. Methodology: A cross-sectional observational study was conducted on 47 pediatric DVI patients at PKU Muhammadiyah Sampangan Hospital, Surakarta. Medical records from January to May 2024 were analyzed. Data were statistically evaluated using Spearman’s test to determine the correlation between variables. Results: Among 47 patients, 57.45% had dengue without warning signs, while 42.55% had dengue with warning signs, with no cases of severe dengue. There was no significant correlation between MCH (p=0.383, r=0.130), MCHC (p=0.457, r=-0.111), or PHR (p=0.064, r=-0.273) and the severity of DVI. Applications/Originality/Value: This study examines the roles of MCH, MCHC, and PHR in pediatric dengue virus infection, finding no significant correlation with disease severity. It provides a basis for future research on alternative hematological markers to enhance clinical assessment. This research introduces PHR as a novel parameter in dengue studies, providing a unique perspective on its potential relevance to disease pathophysiology.
Correlation of Length of Fever before Hospital Admission, Hematocrit, Platelet Count, and Leukocytes with Length of Hospitalization Dengue Virus Infection Patients in Children Pambudi, Nasrurrofiq Risvana Bayu; Puspitasari, Metana; Jatmiko, Safari Wahyu; Aisyah, Riandini; Alfajri, Asri
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5525

Abstract

Purpose: To analyze the relationship between fever duration before admission, hematocrit, platelet count, and leukocyte count with length of hospital stay in pediatric patients with dengue infection. Methodology: This observational study with cross-sectional design was conducted at PKU Muhammadiyah Sampangan Hospital, Surakarta, using secondary data from medical records. Forty pediatric patients were selected through consecutive non-probability sampling technique. Statistical analysis was performed with Spearman correlation test using statistical applications. Results: There was a significant association between fever duration before admission and length of hospitalization (r = -0.407, p = 0.009). However, there was no significant association between hematocrit (r = 0.136, p = 0.403), platelet count (r = 0.101, p = 0.536), or leukocyte count (r = 0.111, p = 0.496) with length of hospitalization. Applications/Originality/Value: This study highlights the importance of early detection and intervention in managing pediatric dengue cases. The significant correlation found between fever duration prior to admission and length of stay underscores the need for prompt treatment to minimize hospital stay due to associated inflammation in the body. In contrast, the lack of significant associations between hematocrit, platelet count, leukocyte level and duration of hospitalization highlights the complexity of factors influencing outcomes and the need to explore other prognostic markers. This study conducted in an endemic region of Indonesia contributes to understanding the management of dengue virus infection and underscores the importance of a comprehensive multifactorial approach to improve patient care strategies.
Blood Parameters and Length of Hospitalization in Pediatric Dengue Virus Infection Patients Salsabiela, Salwa; Puspitasari, Metana; Jatmiko, Safari Wahyu
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5539

Abstract

This research aims to evaluate the correlation between erythrocyte level, hematocrit, hemoglobin, and Hb/RDW ratio with the length of hospitalization in pediatric patients with DVI. This observational study used a cross-sectional design and analyzed secondary data from 41 pediatric DVI patients at PKU Muhammadiyah Sampangan Surakarta Hospital. The correlation between hematological parameters and length of hospitalization was analyzed using the Spearman test. Laboratory results showed a mean erythrocyte count of 5.05 million cells/nL (SD 0.61), a median hematocrit of 39.5%, hemoglobin of 13.6 g/dL, and Hb/RDW ratio of 1.03. Bivariate correlation test showed erythrocyte level (r = 0.027, p = 0.867), hematocrit (r = -0.004, p = 0.983), hemoglobin (r = 0.079, p = 0.625), and Hb/RDW ratio (r = 0.116, p = 0.472) showed no significant association with length of hospitalization. This study provides insights into the relationship between hematological parameters and the length of hospital stay in pediatric dengue patients. While no significant correlation was found, it highlights the complexity of factors influencing outcomes and the need to explore other prognostic markers. Conducted in an Indonesian endemic region, the research contributes to understanding DVI management and underscores the importance of a comprehensive, multifactorial approach to improving patient care strategies.
Penapisan Diabetes Melitus Melalui Pemeriksaan Kadar Gula Darah Sewaktu: Screening for Diabetes Mellitus Through Blood Sugar Level Examination Jatmiko, Safari Wahyu
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 6 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i6.8761

Abstract

Surakarta has a population of 148,992 people living in five sub-districts, namely Laweyan, Serengan, Pasar Kliwon, Banjasari, and Jebres. Jebres District has four Community Health Centers that routinely report on diabetes mellitus (DM) health services. DM cases in the Surakarta area were 12,105 patients. The highest DM cases were in the Jebres District area, with 3,392 (27.89%) residents suffering from DM. DM cases have increased from year to year. The cause of the increase in DM cases is lifestyle changes and a lack of DM screening. The hope is that this activity can reduce the number of DM sufferers in the Jebres District area. Activities have been carried out by checking blood sugar levels at any time. The results obtained were that the blood sugar levels of study participants on Sunday morning at the Jagalan Mosque were 124.5 (47.75) mg/dL. These results indicate that blood sugar levels are still within normal limits, so in the future education and regular screening are needed to prevent cases of DM.
Potential Effect of Orthosiphon aristatus Leaf Extract in Improving Collagen 1 Alpha 1 Expression in Hyperglycemia-Induced Rats Aisyah, Riandini; Risanti, Erika Diana; Jatmiko, Safari Wahyu; Asfarina, Fatin
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.357-361

Abstract

Diabetes mellitus involves many mechanisms, the collagen metabolism pathway with very complex interactions and its regulation can contribute to the development of diabetes complications. The collagen 1 alpha 1  (COL1A1) gene plays an important role in the diabetes melitus pathway in adipose tissue by regulating adipocyte function, insulin resistance, and glucose metabolism. COL1A1 expression  is positively correlated with insulin resistance and negatively correlated with insulin sensitivity and is identified as a potential therapeutic target for type 2 diabetes. The cat's whisker plant (Ortosiphon aristatus) pharmacologically has hypoglycemic activity and increases insulin expression. This study aims to observe the potential of cat whisker leaf extract (Ortosiphon aristatus) in increasing the expression of the COL1A1 gene and is protective against increased blood sugar levels in  hyperglycemia-induced Rattus norvegicus. The experimental design with pretest and posttest controlled group design was carried out by dividing 18 test animals into six groups of non-diabetic negative control, diabetic negative control, metformin as positive control, doses of 100, 200, and 400 mg/kgBW. Induction of hyperglycemia with streptozotocin 65 mg/kgBW and nicotinamide 230 mg/kgBW peritoneal injection. The extract treatment is given for 14 days. Blood sugar level measurements were carried out at the treatment’s beginning and end. Adipose tissue was taken to examine COL1A1 gene expression by real time PCR technique by calculating the ratio of the cycle of tresh-hold COL1A1 to the internal ?-actin gene. The results of Kruskall Wallis test showed no significant difference in COL1A1 gene expression between groups and the Spearmen correlation test showed no relationship between blood sugar levels and COL1A1 gene expression (p>0.05). There was a decrease in blood sugar levels before and after treatment for all treatment groups.
Deteksi Dini Risiko Sindrom Metabolik pada Remaja di Daerah Urban dan Rural: Early Detection of Metabolic Syndrome Risk in Adolescents in Urban and Rural Areas Aisyah, Riandini; Jatmiko, Safari Wahyu; Bestari, Rochmadina Suci; Supraba, Intan Pratiwi; Utami, Indari; Wibowo, Haryo Kunto; Mapa, Anna Rochim; Utami, Aurelia Ratna; Anggitaratri, Zakia Novi; Haliza, Sheli Nur; Fitri, Alifah Aulia; Anam, Ilham Hafizha Maulana; Azenta, Moch. Tabriz; Syahida, Safira; Sulistiyo, Azka Hafiy; Brilliantama, Fandy Akbar; Maulida, Amira Hasna; Wafiq, Muhammad Azzim; Kamila, Aulida Azkia; Rohman, Raihan Fadzlur
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 8 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i8.9733

Abstract

Metabolic syndrome is a collection of metabolic disorders that are closely related to an increased risk of developing diabetes mellitus and cardiovascular diseases in obese adolescents. Metabolic syndrome in adolescents is still reversible with varying timeframes. In adolescents with metabolic syndrome, the transition from homeostasis with normal blood sugar levels to type 2 diabetes occurs more rapidly compared to adults. Early diagnosis of metabolic syndrome is essential for prevention through lifestyle changes. Living in urban areas has a higher risk of obesity compared to living in rural areas after controlling for other variables. This activity aims to initially screen metabolic syndrome in middle school adolescents in urban and rural areas. The measurement of metabolic syndrome parameters involved 107 students, consisting of 47 middle school students in urban areas and 60 in rural areas. The measurement and data analysis results showed significant differences in body mass index (p<0,001), waist size (p=0.03), waist circumference (p=0.007), and upper arm circumference (p=0.002) between students in urban and rural areas, while blood sugar levels, blood pressure, and neck circumference did not show significant differences.
PENINGKATAN PENGETAHUAN TENTANG DUKUNGAN KELUARGA TERHADAP GAYA HIDUP SEHAT REMAJA PADA SISWA SMP MUHAMMADIYAH DI SURAKARTA Bestari, Rochmadina Suci; Aisyah, Riandini; Jatmiko, Safari Wahyu; Utami, Aurelia Ratna; Syahida, Safira; Nurhaliza, Sheli; Aryanto; Suryani, Latifah; Sholeh, Muhammad Dzikru Irfan
Jurnal Pengabdian Masyarakat Medika Vol 5. No. 2, September 2025
Publisher : Universitas Muhamamdiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jpmmedika.v5i2.12590

Abstract

ABSTRAK Kesehatan remaja, baik secara fisik maupun mental, telah menjadi isu kesehatan masyarakat yang semakin signifikan dan menjadi perhatian serius secara global, termasuk di Indonesia. Faktor-faktor yang berkontribusi terhadap masalah kesehatan ini meliputi kebiasaan gaya hidup dan kurangnya pengetahuan kesehatan. Keluarga memegang peran yang sangat krusial dan mendasar dalam membentuk perilaku kesehatan remaja. Siswa SMP Muhammadiyah perlu mengetahui pentingnya dukungan keluarga untuk gaya hidup sehat mereka. Tujuan kegiatan ini adalah untuk mengetahui adanya peningkatan pengetahuan tentang dukungan keluarga dalam penarapan gaya hidup sehat remaja pada siswa SMP Muhammadiyah PK Surakarta. Metode pelaksanaannya adalah pretes, penyampaian materi oleh dokter menggunakan presentasi slide, kemudian postes. Hasil yang didapatkan adalah rata-rata nilai pretes adalah 63,36, rata-rata nilai postes adalah 97,59, rata-rata kenaikan skor sebesar 34,54. Dari analisis t-test, didapatkan p<0,001 pada siswa 9A dan siswa 9B yang menunjukkan bahwa terdapat perbedaan yang signifikan pada pengetahuan siswa sebelum dan sesudah edukasi. Simpulan kegiatan ini adalah terdapat peningkatan pengetahuan siswa-siswi SMP tentang peran dukungan keluarga pada gaya hidup sehat mereka.   ABSTRACT Adolescent health, both physically and mentally, has become a significant public health issue and a serious concern globally, including in Indonesia. Factors contributing to this health problem include lifestyle habits and lack of health knowledge. Families play a crucial and fundamental role in shaping adolescent health behaviors. Muhammadiyah junior high school students need to know the importance of family support for their healthy lifestyles. The objective of this study was to determine whether there was an increase in knowledge about family support for healthy lifestyles among junior high school students at Muhammadiyah PK Surakarta. The study was conducted using a pretest, presentation of material by a doctor using slides, and a posttest. The results obtained were an average pretest score of 63.36, an average posttest score of 97.59, and an average score increase of 34.54. From the t-test analysis, p<0.001 was obtained for students in class 9A and class 9B, indicating a significant difference in students' knowledge before and after the education program. The conclusion of this activity is that there was an increase in the knowledge of junior high school students about the role of family support in their healthy lifestyle.
Co-Authors Agustina, Dinda Dwi Ahmad Alrizaldi Alfajri, Asri Alim, Fika Nurul Anam, Ilham Hafizha Maulana Andri Sugeng Prasetyo Anggitaratri, Zakia Novi Anika Candrasari Annas Syahirul Nugraha Annas Syahirul Nugraha, Annas Syahirul Annisa Maulidia Aprida Putri Arkan Adi Widiya Arkan Adi Widiya, Arkan Adi Aryanto Asfarina, Fatin Aulia Hanif Azenta, Moch. Tabriz Azhim Rahmawati Azhim Rahmawati, Azhim Brilliantama, Fandy Akbar Devi Usdiana Rosyidah Dodik Nursanto Edi Dharmana Em Sutrisna Erika Diana Risanti Fathiyya Noor Affifah Fauzi, Favian Arriella Shabri Ikmal Fitka Romanda Fitri, Alifah Aulia Graffico Eryza Oldiara Haliza, Sheli Nur Hanif, Aulia Hasna Zahro Iftikhonsa Iin Novita Nurhidayati Mahmuda Ishmah Nur Faizah Kamila, Aulida Azkia Kumala, Aswa Arsa Lestari, Nining Listiana Masyita Dewi Lisyani Suromo, Lisyani Mapa, Anna Rochim Marsya, Vitania Maulida, Amira Hasna Muhammad Adha Muhammad Alim Abdulmajid Hidayatulloh Nadia Wdihi Aqmarina Nida Faradisa Fauziyah Nining Lestari Nur Mahmudah Nurhaliza, Sheli Pambudi, Nasrurrofiq Risvana Bayu Pintakasari Widyaningtyas Puspitasari, Metana Retno Sintowati - Retno Siryaningsih Retno Siryaningsih, Retno Riandini Aisyah Rochmadina Suci Bestari Rohman, Raihan Fadzlur Salsabiela, Salwa Salsabila, Nabila Mutia Sholeh, Muhammad Dzikru Irfan Sigit Widyatmoko Sri Wahyuni Sulistiyo, Azka Hafiy Supraba, Intan Pratiwi Suryani, Latifah Syahida, Safira Tara , Irmanawati Audhina Nirmala Tri Agustina, Tri Utami, Aurelia Ratna Utami, Indari Wafiq, Muhammad Azzim Wibowo, Haryo Kunto Yulia Intan Kania Yunitama, Alifa Agil Dhillu