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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. Jurnal Kedokteran Brawijaya Biology, Medicine, & Natural Product Chemistry Biomedika Bioeksperimen: Jurnal Penelitian Biologi Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Jurnal Kedokteran dan Kesehatan Herb-Medicine Journal Indonesian Journal of Medicine PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Litbang Sukowati : Media Penelitian dan Pengembangan Cermin Dunia Kedokteran Proceeding ISETH (International Summit on Science, Technology, and Humanity) Prosiding University Research Colloquium Jurnal Pengabdian Masyarakat Medika JUKEJ: Jurnal Kesehatan Jompa
Safari Wahyu Jatmiko
Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Correlations between Age and Hypertension on Diabetic Foot Ulcer Marsya, Vitania; Mahmuda, Iin Novita Nurhidayati; Lestari, Nining; Jatmiko, Safari Wahyu
Indonesian Journal of Medicine Vol. 8 No. 2 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.2.622

Abstract

Background:  Diabetic foot ulcer is a wound located on the foot of a diabetic patient, which is related to peripheral neuropathy or arterial disease. Hypertension can be related to diabetic foot ulcer by its mechanism that caused peripheral artery disease. Age also can be the one of risk factors for diabetic foot ulcers, because aging occurs a reduction of insulin secretion, even insulin resistance. Insulin resistance occurs in macroangiopathy. The purpose of this study is to determine the correlation between age and hypertension with diabetic foot ulcers.Subjects and Method:  This was a cross-sectional study conducted at Arafah Islamic Hospital Rembang, Central Java. The dependent variable is diabetic ulcers. The independent variables were age and hypertension. A sample of diabetic patients using medical records from January 2022-June 2022. Data were collected using purposive sampling and analyzed using the Chi-Square test, and regression logistic test.Results:  Significant correlation was found between age (OR= 3.80; 95% CI= 1.38 to 10.57; p<0.001) and hypertension (OR= 8.12; 95% CI= 2.70 to 24.40; p<0.001) with a diabetic foot ulcer.Conclusion:  There is a significant correlation between age and hypertension with diabetic foot ulcers.Keywords:  age, hypertension, diabetes, diabetic foot ulcers.Correspondence:  Nining Lestari. Bachelor of Medicine, Muhammadiyah University of Surakarta. Jl. A. Yani, Mendungan, Pabelan, Kartasura, Sukoharjo 57162, Central Jawa, Indonesia. Email: nl209@ums.ac.id. Mobile: +62852-2939-0353Indonesian Journal of Medicine (2023), 08(02): 179-185https://doi.org/10.26911/theijmed.2023.08.02.07 
Optimalisasi Jumantik dan Pemberantasan Sarang Nyamuk dalam Mencegah Penularan Infeksi Virus Dengue pada Kader di Desa Karangbangun: Optimizing Human Resources and the Environment in Preventing the Transmission of Dengue Virus Infection to Cadres in Karangbangun Village Bestari, Rochmadina Suci; Jatmiko, Safari Wahyu; Aisyah, Riandini; Wahyuni, Sri; Mahmudah, Nur; Agustina, Tri; Salsabila, Nabila Mutia; Adha, Muhammad; Kumala, Aswa Arsa; Fauzi, Favian Arriella Shabri Ikmal
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 3 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i3.8528

Abstract

Dengue virus infection (IVD) is still a health problem in Indonesia. In Karangbangun Matesih Karanganyar Village, there were 13 cases of IVD in April 2024. The government program to eradicate IVD vectors has not been implemented optimally. Karangbangun Village has potential healthcare resources to be used as agents for eradicating IVD vectors. So far there has been no education about the function of jumantik as larva monitors and mosquito nest eradication (PSN). Therefore, it is necessary to provide education about the function of jumantik and PSN to health cadres in Karangbangun Village. The aim and benefit of this community service activity is that the health cadres of Karangbangun Matesih Karanganyar Village understand the function of jumantik and PSN. The extension activity was preceded by a pretest, and speaker presentation and ended with a posttest. The results of the education showed an increase in health cadres' knowledge after the education based on a comparison of pre-test and post-test scores (p<0.001; Effect Size (Cohen's d) = -1.993). Education about the function of jumantik and eradicating mosquito nests to health cadres in Karangbangun Village increased knowledge significantly and the average post-test score showed an increase.
PENINGKATAN PENGETAHUAN DEMAM BERDARAH DAN FAKTOR RISIKO YANG DAPAT DIMODIFIKASI PADA KADER KESEHATAN DESA KARANGBANGUN MELALUI EDUKASI Jatmiko, Safari Wahyu; Aisyah, Riandini; Wahyuni, Sri; Mahmudah, Nur; Bestari, Rochmadina Suci; Agustina, Tri; Wafiq, Muhammad Azzim; Tara , Irmanawati Audhina Nirmala
Jurnal Pengabdian Masyarakat Medika Vol 5. No. 1, Maret 2025
Publisher : Universitas Muhamamdiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jpmmedika.v5i1.6966

Abstract

ABSTRAK Kondisi geografis desa Karangbangun, Matesih, Karanganyar secara teori relatif kurang berisiko untuk mengalami kejadian infeksi virus dengue (IVD). Akan tetapi, fakta di lapangan menunjukkan bahwa terjadi 13 kasus IVD pada bulan April 2024. Sumber daya desa Karangbangun strategis dalam mendukung pemberantasan IVD. Sumber daya manusia berupa kader gizi dan kader kesehatan yang potensial di desa Karangbangun potensial untuk ditingkatkan dalam rangka eradikasi IVD. Sumber daya tersebut perlu dilakukan edukasi untuk optimalisasi eradikasi IVD. Selama ini belum ada edukasi yang tepat mengenai hal tersebut sehingga perlu diadakan edukasi mengenai penyakit IVD beserta faktor risiko yang memperberat IVD. Tujuan dan manfaat kegiatan pengabdian masyarakat ini adalah kader kesehatan dan kader gizi desa Karangbangun, kecamatan Matesih memahami tentang IVD beserta faktor risiko yang memperberat IVD. Penyuluhan kesehatan dengan melakukan pretes dan postes pasca penyuluhan dilakukan untuk mengatasi masalah permasalahan mitra. Hasil penyuluhan adalah terjadi peningkatan pengetahuan kader kesehatan pasca penyuluhan berdasarkan perbandingan median nilai ptretes 6 (2) dan postes 7 (2) dengan nilai p=0,002 dan rB=0,59. Edukasi kesehatan terhadap kader kesehatan desa Karangbangun dengan metode ceramah berhasil meningkatkan pengetahuan kader mengenai IVD dan faktor risiko yang memperberat IVD.   ABSTRACT The geographical conditions of Karangbangun Village, Matesih, Karanganyar, are theoretically considered to have a relatively low risk of dengue virus infection (DVI). However, field data revealed 13 DVI cases in April 2024. Karangbangun Village has strategic resources to support DVI eradication, including potential health and nutrition cadres who can be further empowered. These resources require education to optimize DVI eradication efforts.  Currently, there is no adequate education on this matter, highlighting the need for awareness programs on DVI and its aggravating risk factors. The goal and benefit of this community service activity are to equip health and nutrition cadres in Karangbangun Village, Matesih District, with knowledge about DVI and its risk factors. A health education session, including pre- and post-tests, was conducted to address partner issues. The results showed an increase in cadre knowledge, with a median pre-test score of 6 (2) and a post-test score of 7 (2), yielding p=0.002 and rB=0.59. Health education through lectures successfully improved cadres' understanding of DVI and its risk factors.
Correlation of Eosinophil-basophil Count and Ratio with Length of Stay in Children Dengue Infection Yunitama, Alifa Agil Dhillu; Puspitasari, Metana; Jatmiko, Safari Wahyu; Fauziyah, Nida Faradisa
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5486

Abstract

Purpose: This study purpose is to determine the correlation between the number of absolute eosinophils, absolute basophils, and eosinophil-basophil ratio (EBR) with the length of stay of pediatric patients with dengue virus infection. Methodology: The study design used cross-sectional. The samples used in this study were taken from routine hematologic laboratory medical record data for the period January-October 2024, using consecutive non-probability sampling technique. Results: 49 samples were obtained and met the restriction criteria as subjects of this study. The results of the Spearman correlation bivariate test showed that the number of absolute eosinophil count, absolute basophil count, and EBR with length of stay had statistical data results respectively p = 0.139, p = 0.993, and p = 0.536. Applications/Originality/Value: This study provides a reference in laboratory results to determine the length of stay (LOS) in children with dengue virus infection.
Correlation of Dengue Infection Severity with Abdominal Pain, Delta Hematocrit, Platelet Count, and Delta Hematocrit-Platelet Ratio in Pediatric Patients Agustina, Dinda Dwi; Puspitasari, Metana; Jatmiko, Safari Wahyu
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5503

Abstract

Purpose: This study aimed to determine the correlation between the severity of dengue infection and abdominal pain, delta hematocrit, platelet levels, and the delta hematocrit-platelet ratio. Methodology: the study used a correlational observational design with a cross-sectional approach. Data were obtained from the medical records of dengue infection patients at PKU Muhammadiyah Sampangan Hospital from October–November 2024. A total of 39 samples were selected using a consecutive non-probability sampling technique. Data analysis was performed using JASP statistical software version 0.19.1.0. Results: The study revealed no significant relationship between the severity of dengue infection and abdominal pain (p=0.089), delta hematocrit (p=0.589), platelet levels (p=0.068), or the delta hematocrit-platelet ratio (p=0.740). Applications/Originality/Value: This study provides valuable insights into the limitations of individual clinical and laboratory parameters, emphasizing the need for a comprehensive approach to assessing dengue severity in pediatric patients.
Correlation of Mean Corpuscular Hemoglobin, Mean Corpuscular Hemoglobin Concentration and Platelet to Hemoglobin Ratio with the Degree of Dengue Virus Infection in Pediatric Patients Alim, Fika Nurul; Jatmiko, Safari Wahyu; Puspitasari, Metana
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5511

Abstract

Purpose: This study aimed to evaluate the correlation between MCH, MCHC, and PHR with the severity of DVI in pediatric patients. Methodology: A cross-sectional observational study was conducted on 47 pediatric DVI patients at PKU Muhammadiyah Sampangan Hospital, Surakarta. Medical records from January to May 2024 were analyzed. Data were statistically evaluated using Spearman’s test to determine the correlation between variables. Results: Among 47 patients, 57.45% had dengue without warning signs, while 42.55% had dengue with warning signs, with no cases of severe dengue. There was no significant correlation between MCH (p=0.383, r=0.130), MCHC (p=0.457, r=-0.111), or PHR (p=0.064, r=-0.273) and the severity of DVI. Applications/Originality/Value: This study examines the roles of MCH, MCHC, and PHR in pediatric dengue virus infection, finding no significant correlation with disease severity. It provides a basis for future research on alternative hematological markers to enhance clinical assessment. This research introduces PHR as a novel parameter in dengue studies, providing a unique perspective on its potential relevance to disease pathophysiology.
Correlation of Length of Fever before Hospital Admission, Hematocrit, Platelet Count, and Leukocytes with Length of Hospitalization Dengue Virus Infection Patients in Children Pambudi, Nasrurrofiq Risvana Bayu; Puspitasari, Metana; Jatmiko, Safari Wahyu; Aisyah, Riandini; Alfajri, Asri
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5525

Abstract

Purpose: To analyze the relationship between fever duration before admission, hematocrit, platelet count, and leukocyte count with length of hospital stay in pediatric patients with dengue infection. Methodology: This observational study with cross-sectional design was conducted at PKU Muhammadiyah Sampangan Hospital, Surakarta, using secondary data from medical records. Forty pediatric patients were selected through consecutive non-probability sampling technique. Statistical analysis was performed with Spearman correlation test using statistical applications. Results: There was a significant association between fever duration before admission and length of hospitalization (r = -0.407, p = 0.009). However, there was no significant association between hematocrit (r = 0.136, p = 0.403), platelet count (r = 0.101, p = 0.536), or leukocyte count (r = 0.111, p = 0.496) with length of hospitalization. Applications/Originality/Value: This study highlights the importance of early detection and intervention in managing pediatric dengue cases. The significant correlation found between fever duration prior to admission and length of stay underscores the need for prompt treatment to minimize hospital stay due to associated inflammation in the body. In contrast, the lack of significant associations between hematocrit, platelet count, leukocyte level and duration of hospitalization highlights the complexity of factors influencing outcomes and the need to explore other prognostic markers. This study conducted in an endemic region of Indonesia contributes to understanding the management of dengue virus infection and underscores the importance of a comprehensive multifactorial approach to improve patient care strategies.
Blood Parameters and Length of Hospitalization in Pediatric Dengue Virus Infection Patients Salsabiela, Salwa; Puspitasari, Metana; Jatmiko, Safari Wahyu
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5539

Abstract

This research aims to evaluate the correlation between erythrocyte level, hematocrit, hemoglobin, and Hb/RDW ratio with the length of hospitalization in pediatric patients with DVI. This observational study used a cross-sectional design and analyzed secondary data from 41 pediatric DVI patients at PKU Muhammadiyah Sampangan Surakarta Hospital. The correlation between hematological parameters and length of hospitalization was analyzed using the Spearman test. Laboratory results showed a mean erythrocyte count of 5.05 million cells/nL (SD 0.61), a median hematocrit of 39.5%, hemoglobin of 13.6 g/dL, and Hb/RDW ratio of 1.03. Bivariate correlation test showed erythrocyte level (r = 0.027, p = 0.867), hematocrit (r = -0.004, p = 0.983), hemoglobin (r = 0.079, p = 0.625), and Hb/RDW ratio (r = 0.116, p = 0.472) showed no significant association with length of hospitalization. This study provides insights into the relationship between hematological parameters and the length of hospital stay in pediatric dengue patients. While no significant correlation was found, it highlights the complexity of factors influencing outcomes and the need to explore other prognostic markers. Conducted in an Indonesian endemic region, the research contributes to understanding DVI management and underscores the importance of a comprehensive, multifactorial approach to improving patient care strategies.
Penapisan Diabetes Melitus Melalui Pemeriksaan Kadar Gula Darah Sewaktu: Screening for Diabetes Mellitus Through Blood Sugar Level Examination Jatmiko, Safari Wahyu
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 6 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i6.8761

Abstract

Surakarta has a population of 148,992 people living in five sub-districts, namely Laweyan, Serengan, Pasar Kliwon, Banjasari, and Jebres. Jebres District has four Community Health Centers that routinely report on diabetes mellitus (DM) health services. DM cases in the Surakarta area were 12,105 patients. The highest DM cases were in the Jebres District area, with 3,392 (27.89%) residents suffering from DM. DM cases have increased from year to year. The cause of the increase in DM cases is lifestyle changes and a lack of DM screening. The hope is that this activity can reduce the number of DM sufferers in the Jebres District area. Activities have been carried out by checking blood sugar levels at any time. The results obtained were that the blood sugar levels of study participants on Sunday morning at the Jagalan Mosque were 124.5 (47.75) mg/dL. These results indicate that blood sugar levels are still within normal limits, so in the future education and regular screening are needed to prevent cases of DM.
Potential Effect of Orthosiphon aristatus Leaf Extract in Improving Collagen 1 Alpha 1 Expression in Hyperglycemia-Induced Rats Aisyah, Riandini; Risanti, Erika Diana; Jatmiko, Safari Wahyu; Asfarina, Fatin
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.357-361

Abstract

Diabetes mellitus involves many mechanisms, the collagen metabolism pathway with very complex interactions and its regulation can contribute to the development of diabetes complications. The collagen 1 alpha 1  (COL1A1) gene plays an important role in the diabetes melitus pathway in adipose tissue by regulating adipocyte function, insulin resistance, and glucose metabolism. COL1A1 expression  is positively correlated with insulin resistance and negatively correlated with insulin sensitivity and is identified as a potential therapeutic target for type 2 diabetes. The cat's whisker plant (Ortosiphon aristatus) pharmacologically has hypoglycemic activity and increases insulin expression. This study aims to observe the potential of cat whisker leaf extract (Ortosiphon aristatus) in increasing the expression of the COL1A1 gene and is protective against increased blood sugar levels in  hyperglycemia-induced Rattus norvegicus. The experimental design with pretest and posttest controlled group design was carried out by dividing 18 test animals into six groups of non-diabetic negative control, diabetic negative control, metformin as positive control, doses of 100, 200, and 400 mg/kgBW. Induction of hyperglycemia with streptozotocin 65 mg/kgBW and nicotinamide 230 mg/kgBW peritoneal injection. The extract treatment is given for 14 days. Blood sugar level measurements were carried out at the treatment’s beginning and end. Adipose tissue was taken to examine COL1A1 gene expression by real time PCR technique by calculating the ratio of the cycle of tresh-hold COL1A1 to the internal ?-actin gene. The results of Kruskall Wallis test showed no significant difference in COL1A1 gene expression between groups and the Spearmen correlation test showed no relationship between blood sugar levels and COL1A1 gene expression (p>0.05). There was a decrease in blood sugar levels before and after treatment for all treatment groups.
Co-Authors Affifah, Fathiyya Noor Agustina, Dinda Dwi Ahmad Alrizaldi Alfajri, Asri Alim, Fika Nurul Anam, Ilham Hafizha Maulana Anggitaratri, Zakia Novi Anika Candrasari Annas Syahirul Nugraha Annas Syahirul Nugraha, Annas Syahirul Annisa Maulidia Aprida Putri Aqmarina, Nadia Wdihi Arif Pristianto Arkan Adi Widiya Arkan Adi Widiya, Arkan Adi Aryanto Asfarina, Fatin Aulia Hanif Azenta, Moch. Tabriz Azhim Rahmawati Azhim Rahmawati, Azhim Brilliantama, Fandy Akbar Devi Usdiana Rosyidah Dodik Nursanto Edi Dharmana Em Sutrisna Erika Diana Risanti Faizah, Ishmah Nur Fauzi, Favian Arriella Shabri Ikmal Fitka Romanda Fitri, Alifah Aulia Graffico Eryza Oldiara Haliza, Sheli Nur Hanif, Aulia Hasna Zahro Iftikhonsa Iin Novita Nurhidayati Mahmuda Kamila, Aulida Azkia Kania, Yulia Intan Komalasari, Dwi Rosella Kumala, Aswa Arsa Lestari, Nining Listiana Masyita Dewi Lisyani Suromo, Lisyani Mapa, Anna Rochim Marsya, Vitania Maulida, Amira Hasna Muhammad Adha Muhammad Alim Abdulmajid Hidayatulloh Nadia Wdihi Aqmarina Nida Faradisa Fauziyah Nining Lestari Nur Mahmudah Nurhaliza, Sheli Pambudi, Nasrurrofiq Risvana Bayu Pintakasari Widyaningtyas Prasetyo, Andri Sugeng Puspitasari, Metana Putri, Aprida Retno Sintowati - Retno Siryaningsih Retno Siryaningsih, Retno Riandini Aisyah Rochmadina Suci Bestari Rohman, Raihan Fadzlur Salsabiela, Salwa Salsabila, Nabila Mutia Sholeh, Muhammad Dzikru Irfan Sigit Widyatmoko Sri Wahyuni Sulistiyo, Azka Hafiy Supraba, Intan Pratiwi Suryani, Latifah Syahida, Safira Tara , Irmanawati Audhina Nirmala Tri Agustina, Tri Utami, Aurelia Ratna Utami, Indari Wafiq, Muhammad Azzim Wibowo, Haryo Kunto Widyaningtyas, Pintakasari Yunitama, Alifa Agil Dhillu Zulfah, Khairina