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Journal : JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)

SECONDARY PREVENTION TO REDUCE THE OCCURRENCE OF RECURRENT STROKE ON ISCHEMIC STROKE Hidayah Karuniawati; Zullies Ikawati; Abdul Gofir
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 5, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.23

Abstract

One of the purpose from stroke theraphy is to prevent recurrent stroke using secondary prevention by administering antiplatelet/anticoagulant, antihypertensive, antidyslipidemia, and antihyperglycemic. This study aimed to find the influence of secondary prevention on the occurrence of recurrent stroke and determine the factors that involve in the occurrence of recurrent stroke. This research was conducted with a quantitative approach and retrospective case-control study. The subjects were 165 respondents consisted of 82 respondents in the case group and 83 respondents in the control group. Data were analyzed using bivariate/chi square and logistic regression multivariate test. The result showed that the secondary prevention and patient’s compliance reduced the incident of recurrent stroke. The rate of recurrent stoke was decreased from 68% to 24% by antiplatelet therapy and compliance, from 69% to 23% by antihypertensive and compliance, from 54% to 29% by antidislipidemic and compliance, from 52% to 23% by antihiperglikemic and compliance, and the combination of these four secondary preventions reduced the recurrent stroke from 52% to 13%. Multivariate analysis showed that the several factors involved in determining the rate of recurrent stroke, namely patiens who did not use antihypertensive therapy (P=0,000; OR 9.871), had systolic blood pressure≥140mmHg (P=0,011; OR 3,156), HDL<40mg/dl (P=0,005; OR 3,594), and the lack of exercise (P=0,048; OR 2,365).Keyword: recurrent stroke, secondary prevention, compliance, antihypertensive therapy
Factors Affecting Non-Adherence to Secondary Stroke Prevention Therapy in Ischemic Stroke Patients Zakky Cholisoh; Hidayah Karuniawati; Tanti Azizah; Zaenab Zaenab; Laila Nur Hekmah
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 8, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.34434

Abstract

Stroke is cardiovascular disease that causes the world's highest disability and is the most prevalence disease after heart disease and cancer. Stroke is caused by circulatory disorders with 80% of the sufferers are diagnosed with ischemic stroke and 20% of them are diagnosed with hemorrhagic stroke. Patients who survive from the first stroke have high risk to have recurrent stroke. American Heart Association/American Stroke Association and Perhimpunan Dokter Spesialis Syaraf Indonesia recommend secondary stroke prevention therapy including antiplatelet/anticoagulant, antihypertensive agents, and antidislipidemia to minimalize the risk of recurrent stroke. Secondary stroke prevention therapy is only the first step. Patients need to be adhere to those therapies. The non-adherence will increase the risk of recurrent stroke. The study aimed to determine factors which causing the non-adherence to secondary prevention therapy in patients with ischemic stroke. This was a case control study with concecutive sampling method by interviewing patients who met the inclusion criterias i.e., had been diagnosed and were inpatients due to ischemic stroke, but in the time of interview patients were outpatients, patients were able to communicate and agree to participate in the study.Data was analized by bivariate / chi square test and multivariate logistic regression test. During the study period, 184 respondents met the inclusion criterias. Factors affecting non-adherence in the use of secondary prevention therapy were No one reminded to take medicine p = 0.03; OR 4.51, denial of the disease p = 0,036 OR 214, and tired of taking medicine p = 0,045 OR 1,97.
Co-Authors 'Utsman, Panji A Anifatussaa'dah Abdul Gofir Adiva Tantyas Aurora Adiva Tantyas Aurora, Adiva Tantyas Aflit Nuryulia Praswati Agita Dyah Ayu Kusumaningtyas Ahmad, Farhand Alinda, Oevita Nur Amalya Maulida Ambar Yunita Nugraheni Andi Suhendi Andika Permana Anifatussaa'dah, A Anita Sukmawati Anjani, Rosi Hayyu Ardalia Rinanda Oktaviani Arifah Sri Wahyuni Artamevia, Vanessa Reza Ashari Wahyu Budi Aji Athaillah, Najwa Kayana Auliya, Dhiyahul Basusena, Rahardian Surya Bestari, Mahardika Putri Broto Santoso Burhanudin Ichsan Cholisoh, Zakky Citra, Tia Mella Desti Purnamasari Devi Etivia Purlinda Devi Rahmawati Devi Usdiana Rosyidah Dewi, Meilenia Shinta Kusuma Dewi, Syochi Jannati Pramudya Dewi, Triana Ariska Dian Oktianti Didik Hasmono Dwi Sarbini Dyah Aryani Perwitasari Dzafira, Laila Endang Yuniarti Erindyah Retno Wikantyasning Erna Herawati Erna Herawati, Erna Fahmi, Muhammad Zaini Fahriza Mei Trihatmoko Farida, Rahayu Faridita khoirun Nisa' Febriani, Rizkina Elistya Fidhia Nur Rifaini Fidinillah, Masniar Firda, Fathiyyatu Assadiy Fitriani, Rizki Ainun Fortuna, Tista Ayu Gayuh Ilham Rahmadi Gunawan Setiyadi Hakim, Bilal Rahman Haliza Arzeti Nurseptiria Hanjani, Wildanoor Sekar Haryoto Haryoto Haryoto, H Haya Nabilah Utama Hekmah, Laila Nur Heni Mirawati Hertaliyana, Junita Ayu Hevi Mifta Kumalasari HI, Marsilia Rosa Sinensis Hidajah Rachmawati Ichsan, Burhanudin Ida Maesaroh Ida Maesaroh, Ida Ika Gilar Hapsari Ika Gilar Hapsari, Ika Gilar Ismail, Wan Ismahanisa Karimah, Izqi Keisya, Aulita Khairunnisa, Shafira khusnul khotimah Khusnul Khotimah Kurnia Eryani Kusumastuti, Lina Ayu Laila Dzafira Laila Nur Hekmah Lilla Prapdhani Agni Hajma Lina Ayu Kusumastuti Listiana Masyita Dewi Mahardika Putri Bestari Malik, Muhammad Ihsan Mariska Sri Harlianti Marsilia Rosa Sinensis HI Marsya, Vitania Marwiani Arum Marwiani Arum, Marwiani Maryati Maryati Masniar Fidinillah Maulana, Fahmi Alief Mika Tri Kumala Swandari, Mika Tri Kumala Mufida Alfiana Muhammad Da&#039;i Muhayaroh, Miftah Muhtadi Muhtadi Muhtadi, M Musayyaf, Ahmad Farras Muslihah, Sayyidah Nurul Nisa', Faridita khoirun Nungky Asmaraning Wahyono Nungky Asmaraning Wahyono, Nungky Asmaraning Nur Azizah Nuraini, Filla Rizky Nurseptiria, Haliza Arzeti Nurul Mutmainah Oktaviani, Ardalia Rinanda Oktri Viyanti Panji &#039;Utsman Puteri Santika, Aprilia Raafika Studiviani Rachmalia, Fauniza Marwa Rahardian Surya Basusena Rahma Saritri Cahyani Rahman, Anees Ur Rajali, Ahmad Retno Sintowati - Riandini Aisyah Rif'aini, Fidhia Nur Rifaini, Fidhia Nur Rizki Ainun Fitriani Rizky Wiharti, Irda Rochmadina Suci Bestari Roshitasari, Eva Sakinatul Hayati Salsabela Salsabela Salsabila Salsabila, Aulia Shafa Sanjaya, Muhammad Riyanto Sari, Erlinda Novita Saskia, Adinda Tri Prabandari Sava Salsabila Putri Sayyidah Nurul Muslihah Septi Fatmawati Setyo Nurwaini Sikanaa, Arinaa Manaa Studiviani, Raafika Sulistyarini, Sulistyarini Suprapto Suprapto Suryani - Susilo, Rinto Syahputri, Janies Arly Syaifia, Diska Awal Syam, Ricky Aditya Syifa Imelda Tanti Azizah Tanti Azizah Tanti Azizah Sujono Thalia Fiandra Tia Mella Citra Tista Ayu Fortuna Tista Ayu Fortuna Trihatmoko, Fahriza Mei Trisya Nur Pratiwi Tsaniya, Naura Azka Utama, Haya Nabilah Vitania Marsya Wikantyasning, Erindyah R. Yunika Isnanda Pratiwi Zaenab Zaenab Zaenab Zuhroh Tustika Vieda Zullies Ikawati