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All Journal PROSIDING SEMINAR NASIONAL Biology, Medicine, & Natural Product Chemistry Pharmacon Acta Pharmaciae Indonesia : Acta Pharm Indo JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Indonesian Journal of Medicine Healthy-Mu Journal Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Abdi Geomedisains Jurnal Farmasi Sains dan Praktis Prosiding University Research Colloquium Gaster Jurnal Indonesia Sosial Teknologi Journal of Pharmaceutical and Sciences. Inovasi Jurnal Pengabdian Masyarakat (IJPM) Usadha Journal of Pharmacy Journal of Community Empowerment Kartika : Jurnal Ilmiah Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian Pharmacon: Jurnal Farmasi Indonesia
Hidayah Karuniawati
Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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Journal : Pharmacon

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Evaluasi Rasionalitas dan Efektifitas Penggunaan Antibiotik pada Pasien Pneumonia Pediatrik di Instalasi Rawat Inap Rumah Sakit Pusat Jawa Tengah Bestari, Mahardika Putri; Karuniawati, Hidayah
Pharmacon: Jurnal Farmasi Indonesia Vol 14, No 2 (2017)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v14i2.6524

Abstract

Pneumonia is a respiratory infections disease are caused by bacterial, viral, fungal and parasitic pathogens that cause deaths in children, especially toddlers and increasing number incidents per year. Treatment of pneumonia treated with antibiotics rational and effective because can improve clinical therapeutic effects, minimize drug toxicity, reduce the incidence of resistance that leads to treatment failure, and more economically. The purpose of this study are to determine the rationale and effectiveness of antibiotic therapy. This study was an observational study with retrospective data retrieval using medical record data of pediatric patients diagnosed pneumonia in center hospital, Central Java. The results of 90 cases studied were 60% of patients treated with single antibiotics and 40% of patients treated with combination antibiotics. The most antibiotics given in single therapy were ampicillin (22,2%), amoxicillin (16,7%), and ceftriaxone (15,6%). While antibiotics in combination therapy was ampicillin with gentamicin 31.2%. rationality result analysis was: right indication 100%; proper patients 100%; appropriate medicines 72,2%; appropriate dose 9,23% and rational antibiotics 6,67%. Giving antibiotics ampicillin with gentamycin effective in eradicating bacteria this could be seen with temperature and leukocyte rate down, antibiotics did not improve on symptoms of patients.
EVALUASI PENGGUNAAN ANTIBIOTIK PADA BALITA PENDERITA PNEUMONIA RAWAT INAP DI RSUD “Y” DI KOTA “X” TAHUN 2016 'Utsman, Panji; Karuniawati, Hidayah
Pharmacon: Jurnal Farmasi Indonesia Vol 17, No 1 (2020)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v17i1.5991

Abstract

Pneumonia was pulmonary lung disease called parenchyma caused by microorganism, Pneumonia can be cured byantibiotic to prevent the resistantof bacteria and to improve the effective of the treatment, the right antibiotic must be determining. This research purpose is to determine the accuracy of using antibiotic in toddler patients suffering pneumonia who hospitalized in RSUD ?Y? ?X? City, in 2016. This is nonexperimental research. Data collected retrospectively and was analized descriptively. Samplestaken by purposive sampling method which searched the medical report of toddler patient suffer pneumonia hospitalized in RSUD ?Y?X City, in 2016 which met the inclusion criteria. Reseach accuracy was analized used ?Pedoman Pelayanan Medis Ikatan Dokter Anak Indonesia year 2009? and ?British National Formularium for Children 2011-2012?, Such as indication accuracy, precision medicine accuracy, patient accuracy and drug dose accuracy. The result of the research was found that in 49 toddler patient suffering pneumonia, the kind of antibiotic used was cefotaxime (89,80%), Ampicillin (4,08%), combination of cefotaxime + gentamicin (4,08%) and ampicillin + gentamicin (2,04%). Evaluation of accuracy of the use antibiotic 100% right in indication, precision medicine by 93,87%,100% patient accuracy, and 10,20% drug dose accuracy.
Evaluasi Rasionalitas dan Efektifitas Penggunaan Antibiotik pada Pasien Pneumonia Pediatrik di Instalasi Rawat Inap Rumah Sakit Pusat Jawa Tengah Mahardika Putri Bestari; Hidayah Karuniawati
Pharmacon: Jurnal Farmasi Indonesia Vol 14, No 2 (2017)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v14i2.6524

Abstract

Pneumonia is a respiratory infections disease are caused by bacterial, viral, fungal and parasitic pathogens that cause deaths in children, especially toddlers and increasing number incidents per year. Treatment of pneumonia treated with antibiotics rational and effective because can improve clinical therapeutic effects, minimize drug toxicity, reduce the incidence of resistance that leads to treatment failure, and more economically. The purpose of this study are to determine the rationale and effectiveness of antibiotic therapy. This study was an observational study with retrospective data retrieval using medical record data of pediatric patients diagnosed pneumonia in center hospital, Central Java. The results of 90 cases studied were 60% of patients treated with single antibiotics and 40% of patients treated with combination antibiotics. The most antibiotics given in single therapy were ampicillin (22,2%), amoxicillin (16,7%), and ceftriaxone (15,6%). While antibiotics in combination therapy was ampicillin with gentamicin 31.2%. rationality result analysis was: right indication 100%; proper patients 100%; appropriate medicines 72,2%; appropriate dose 9,23% and rational antibiotics 6,67%. Giving antibiotics ampicillin with gentamycin effective in eradicating bacteria this could be seen with temperature and leukocyte rate down, antibiotics did not improve on symptoms of patients.
Evaluasi Penggunaan Antibiotik pada Balita Penderita Pneumonia Rawat Inap di RSUD “Y” di Kota “X” Tahun 2016 Panji 'Utsman; Hidayah Karuniawati
Pharmacon: Jurnal Farmasi Indonesia Vol 17, No 1 (2020)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v17i1.5991

Abstract

Pneumonia was pulmonary lung disease called parenchyma caused by microorganism, Pneumonia can be cured byantibiotic to prevent the resistantof bacteria and to improve the effective of the treatment, the right antibiotic must be determining. This research purpose is to determine the accuracy of using antibiotic in toddler patients suffering pneumonia who hospitalized in RSUD “Y” “X” City, in 2016. This is nonexperimental research. Data collected retrospectively and was analized descriptively. Samplestaken by purposive sampling method which searched the medical report of toddler patient suffer pneumonia hospitalized in RSUD “Y”X City, in 2016 which met the inclusion criteria. Reseach accuracy was analized used “Pedoman Pelayanan Medis Ikatan Dokter Anak Indonesia year 2009” and “British National Formularium for Children 2011-2012”, Such as indication accuracy, precision medicine accuracy, patient accuracy and drug dose accuracy. The result of the research was found that in 49 toddler patient suffering pneumonia, the kind of antibiotic used was cefotaxime (89,80%), Ampicillin (4,08%), combination of cefotaxime + gentamicin (4,08%) and ampicillin + gentamicin (2,04%). Evaluation of accuracy of the use antibiotic 100% right in indication, precision medicine by 93,87%,100% patient accuracy, and 10,20% drug dose accuracy.
Studi Penggunaan Obat Anti Tuberkulosis (OAT) Tahap Lanjutan pada Pasien Baru BTA Positif Tista Ayu Fortuna; Hidajah Rachmawati; Didik Hasmono; Hidayah Karuniawati
Pharmacon: Jurnal Farmasi Indonesia Vol 19, No 1 (2022)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v19i1.17907

Abstract

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Tuberculosis will cause pain and death if not treated properly. OAT (Antituberculosis Drugs) is a treatment for tuberculosis patients. OAT has different dosage regimens and types of drugs. Treatment of TB patients consists of two phases (intensive and continuation phases). The continuation phase was at to kill dormant bacteria to prevent recurrence in patients. The purpose of this study was to determine and evaluate the pattern of using OAT in patients newly diagnosed rwith smear-positive at the continuation phase. This study is an observational descriptive study with results showing that the pattern of using OAT-KDT in patients was 89% and OAT-Separated was 11%. The pattern of using the OAT-KDT dose was 1x3 2KDT tablets. Another combination of antibiotics given to the patient is cotrimoxazole at a dose of 1x960mg. The side effect of OAT is an increase in serum transaminase and nausea each with a percentage of 23%. Based on the research, it can be concluded that the pattern of using OAT in Tuberculosis patients has followed the guidelines for the management of Tuberculosis treatment.
Antibiotic Evaluation Use towards Diabetic Foot Ulcer Inpatient at Hospital in Surakarta Lilla Prapdhani Agni Hajma; Hidayah Karuniawati; Nurul Mutmainah
Pharmacon: Jurnal Farmasi Indonesia Vol 19, No 2 (2022)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v19i2.20570

Abstract

A diabetic foot ulcer is one of diabetes mellitus type 2 complications indicated by open sores. Because it contains bacteria, it is treated with antibiotics. Improper use of antibiotics could harm patients due to the length of wound healing. This study aims to determine the appropriate of antibiotics in patients with a diabetic foot ulcers. This is a non-experimental research with descriptive analysis approach. The medical records of diabetic foot ulcer patients undergoing inpatient and antibiotic prescribing are observed. The data obtained were analyzed by comparing the use of antibiotics based on the National Health Service guidelines, the Indonesian National Drug Information, and the Drug Information Handbook. The results of this study showed antibiotics used are metronidazole (4.8%), vancomycin (4.8%) and antibiotics combination are ceftriaxone-metronidazole (47.6%), ceftriaxone-metronidazole-clindamycin (4,8%), levofloxacin-azithromycin-ceftriaxone (4.8%), cotrimoxazole-ciprofloxacin (4.8%), metronidazole-meropenem (4.8%), ceftriaxone-metronidazole-gentamicin (4.8%), metronidazole-clindamycin-ciprofloxacin (4.8%), ceftriaxone-levofloxacin (4.8%), and ceftriaxone-metronidazole-ciprofloxacin (9.5%). The evaluation results according to criteria appropriate usage of antibiotics that is 100% appropriate indication, 100% for appropriate of patients, 42.3% for appropriate drug, and 61.9% for the appropriate dose.
Faktor – Faktor yang Mempengaruhi Komplikasi pada Pasien Diabetes Mellitus di RSUD Dr. Moewardi Tista Ayu Fortuna; Hidayah Karuniawati; Desti Purnamasari; Devi Etivia Purlinda
Pharmacon: Jurnal Farmasi Indonesia Vol 20, No 1 (2023)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v20i1.21877

Abstract

Diabetes Mellitus (DM) is a disease characterized by hyperglycemia and disturbances in the metabolism of carbohydrates, fats, and proteins associated with absolute or relative deficiencies of insulin action and or secretion. The main problem for DM sufferers is that more than 50% of diabetic patients do not know about the disease and its complications, so patients will return to the hospital with high blood glucose levels accompanied by various complications. The study aims to determine the factors that can cause complications in patients with diabetes mellitus. This research is a non-experimental study with a cross-sectional approach. The data were analyzed using SPSS with a Chi-square or Kruskal-Wallis and multivariate logistic regression test. Body mass index and duration of diabetes are significantly associated with the incidence of complications (p-value 0.05). Patients with an abnormal body mass index are 4.184x more at risk of complications than patients with a normal body mass index (RR 4.184 CI 1.581 – 11.070). In addition, patients with diabetes duration ≥5 years were 4.121 times more at risk of complications than patients with diabetes durations 5 years (RR 4.121 CI 1.570 – 10.816). The most common complication suffered by diabetic patients in this study was hypertension in 46 patients (41%), and the most common therapeutic regimen received by patients was oral hypoglycemia in 50 patients (52%). 
Antibiotic Evaluation of Hospitalized Pneumonia Patients Using Gyssen or DDD 100 Bed Days or DDD 1000 Patient Days: Review Syam, Ricky Aditya; Karuniawati, Hidayah
Pharmacon: Jurnal Farmasi Indonesia Vol 21, Special Issue 1, 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i0.23589

Abstract

Pneumonia remains one of the significant infectious diseases in society, especially in developing countries such as Indonesia, with its prevalence continuing to increase year after year. Pneumonia caused by bacteria requires antibiotic treatment, increasing antibiotic use and presenting a risk of antibiotic resistance. Therefore, this study evaluated the use of antibiotics in hospitalized pneumonia patients, with qualitative and quantitative approaches using the Gyssen and ATC / DDD methods. The articles taken as research samples involve a publication period from 2013 to 2023. The data included include the Gyssen parameter, DDD/100, and DDD/1000 patient days. The synthesis showed that ceftriaxone and meropenem antibiotics were the top choices, with values of 1547.735 DDD/100 bed days and 3011.2 DDD/1000 patient days, respectively. Ceftriaxone was documented in 21 journals, while in 8 of 37 journals, meropenem considered antibiotic use in hospitalized pneumonia patients. Evaluation of the quality of antibiotic use showed the highest level in category (0) at 93.7%, followed by (IVa) at 67.6%. Meanwhile, analysis of bacterial resistance to antibiotics showed that Klebsiella pneumonia was the most resistant bacteria, especially to antibiotics carbapenems, ertapenem, doripenem, cephalosporin generation 3, extended-spectrum cephalosporin, and piperacillin/tazobactam, with significant values 0.05%. These findings provide deep insight into patterns of antibiotic use in hospitalized pneumonia patients while identifying potential areas for improving the quality of antibiotic use and treating bacterial resistance. Thus, this study contributes to efforts to optimize pneumonia management and reduce the impact of antibiotic resistance in the community.
Co-Authors 'Utsman, Panji A Anifatussaa'dah Abdul Gofir Adiva Tantyas Aurora Adiva Tantyas Aurora, Adiva Tantyas Aflit Nuryulia Praswati Agita Dyah Ayu Kusumaningtyas Ahmad, Farhand Alinda, Oevita Nur Amalya Maulida Ambar Yunita Nugraheni Andi Suhendi Andika Permana Anifatussaa'dah, A Anita Sukmawati Anjani, Rosi Hayyu Ardalia Rinanda Oktaviani Arifah Sri Wahyuni Artamevia, Vanessa Reza Ashari Wahyu Budi Aji Athaillah, Najwa Kayana Auliya, Dhiyahul Basusena, Rahardian Surya Bestari, Mahardika Putri Broto Santoso Burhanudin Ichsan Cholisoh, Zakky Citra, Tia Mella Desti Purnamasari Devi Etivia Purlinda Devi Rahmawati Devi Usdiana Rosyidah Dewi, Meilenia Shinta Kusuma Dewi, Syochi Jannati Pramudya Dewi, Triana Ariska Dian Oktianti Didik Hasmono Dwi Sarbini Dyah Aryani Perwitasari Dzafira, Laila Endang Yuniarti Erindyah Retno Wikantyasning Erna Herawati Erna Herawati, Erna Fahmi, Muhammad Zaini Fahriza Mei Trihatmoko Farida, Rahayu Faridita khoirun Nisa' Febriani, Rizkina Elistya Fidhia Nur Rifaini Fidinillah, Masniar Firda, Fathiyyatu Assadiy Fitriani, Rizki Ainun Fortuna, Tista Ayu Gayuh Ilham Rahmadi Gunawan Setiyadi Hakim, Bilal Rahman Haliza Arzeti Nurseptiria Hanjani, Wildanoor Sekar Haryoto Haryoto Haryoto, H Haya Nabilah Utama Hekmah, Laila Nur Heni Mirawati Hertaliyana, Junita Ayu Hevi Mifta Kumalasari HI, Marsilia Rosa Sinensis Hidajah Rachmawati Ichsan, Burhanudin Ida Maesaroh Ida Maesaroh, Ida Ika Gilar Hapsari Ika Gilar Hapsari, Ika Gilar Ismail, Wan Ismahanisa Karimah, Izqi Keisya, Aulita Khairunnisa, Shafira khusnul khotimah Khusnul Khotimah Kurnia Eryani Kusumastuti, Lina Ayu Laila Dzafira Laila Nur Hekmah Lilla Prapdhani Agni Hajma Lina Ayu Kusumastuti Listiana Masyita Dewi Mahardika Putri Bestari Malik, Muhammad Ihsan Mariska Sri Harlianti Marsilia Rosa Sinensis HI Marsya, Vitania Marwiani Arum Marwiani Arum, Marwiani Maryati Maryati Masniar Fidinillah Maulana, Fahmi Alief Mika Tri Kumala Swandari, Mika Tri Kumala Mufida Alfiana Muhammad Da'i Muhayaroh, Miftah Muhtadi Muhtadi Muhtadi, M Musayyaf, Ahmad Farras Muslihah, Sayyidah Nurul Nisa', Faridita khoirun Nungky Asmaraning Wahyono Nungky Asmaraning Wahyono, Nungky Asmaraning Nur Azizah Nuraini, Filla Rizky Nurseptiria, Haliza Arzeti Nurul Mutmainah Oktaviani, Ardalia Rinanda Oktri Viyanti Panji 'Utsman Puteri Santika, Aprilia Raafika Studiviani Rachmalia, Fauniza Marwa Rahardian Surya Basusena Rahma Saritri Cahyani Rahman, Anees Ur Rajali, Ahmad Retno Sintowati - Riandini Aisyah Rif'aini, Fidhia Nur Rifaini, Fidhia Nur Rizki Ainun Fitriani Rizky Wiharti, Irda Rochmadina Suci Bestari Roshitasari, Eva Sakinatul Hayati Salsabela Salsabela Salsabila Salsabila, Aulia Shafa Sanjaya, Muhammad Riyanto Sari, Erlinda Novita Saskia, Adinda Tri Prabandari Sava Salsabila Putri Sayyidah Nurul Muslihah Septi Fatmawati Setyo Nurwaini Sikanaa, Arinaa Manaa Studiviani, Raafika Sulistyarini, Sulistyarini Suprapto Suprapto Suryani - Susilo, Rinto Syahputri, Janies Arly Syaifia, Diska Awal Syam, Ricky Aditya Syifa Imelda Tanti Azizah Tanti Azizah Tanti Azizah Sujono Thalia Fiandra Tia Mella Citra Tista Ayu Fortuna Tista Ayu Fortuna Trihatmoko, Fahriza Mei Trisya Nur Pratiwi Tsaniya, Naura Azka Utama, Haya Nabilah Vitania Marsya Wikantyasning, Erindyah R. Yunika Isnanda Pratiwi Zaenab Zaenab Zaenab Zuhroh Tustika Vieda Zullies Ikawati