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GAMBARAN PERILAKU MASYARAKAT TENTANG PENGGUNAAN MULTIVITAMIN DI APOTEK-APOTEK KOTA PEKANBARU SELAMA PANDEMI COVID-19 Fina Aryani; Fitri Primawanty; Rahayu Utami; Mustika Furi
Jurnal Penelitian Farmasi Indonesia Vol 12 No 1 (2023): JPFI
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (P3M) Sekolah Tinggi Ilmu Farmasi Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v12i1.1738

Abstract

Telah dilakukan penelitian tentang gambaran perilaku masyarakat tentang penggunaan multivitamin di apotek-apotek kota pekanbaru selama pandemi COVID-19. Penelitian ini bertujuan untuk mengetahui gambaran perilaku masyarakat tentang penggunaan multivitamin di apotek-apotek Kota Pekanbaru selama pandemi COVID-19. Penelitian ini merupakan penelitian deskriptif dengan pengumpulan data secara concurrent melalui pengisian kuesioner online. Teknik pengambilan sampel dalam penelitian ini dilakukan secara non probability sampling dengan metode purposive sampling. Sampel yang menjadi penelitian ini adalah sebanyak 110 responden yang memenuhi kriteria inklusi. Responden penelitian yang memenuhi kriteria inklusi diberikan link kuesioner online yang kemudian diisi oleh responden, kemudian data tersebut diolah dan dianalisis. Berdasarkan hasil penelitian menunjukkan bahwa masyarakat yang memiliki perilaku baik sebanyak 21,81%, masyarakat yang memiliki perilaku cukup adalah sebanyak 74,54%, dan masyarakat yang memiliki perilaku kurang adalah sebanyak 3,63%. Perilaku baik di dominasi oleh responden dengan rentang usia 17-25 tahun, jenis kelamin perempuan, pendidikan tinggi dan status pekerjaan bekerja. Research has been carried out on the description of people's behavior regarding the use of multivitamins in Pekanbaru city pharmacies during the COVID-19 pandemic. This study aims to describe people's behavior regarding the use of multivitamins in Pekanbaru city pharmacies during the COVID-19 pandemic. This study used descriptive design with a concurrent data collection method through filling out online questionnaires. The sampling technique in this study was carried out by non-probability sampling with a purposive sampling method. The sample in this study was 110 respondents who met the inclusion criteria. Research respondents who meet the inclusion criteria are given an online questionnaire link which is then filled in by the respondent, then the data is processed and analyzed by the researcher. Based on the results of the study showed that people who have good behavior are 21.81%, people who have sufficient behavior are 74.54%, and people who have less behavior are 3.63%. Good behavior is dominated by respondents with an age range of 17-25 years, female gender, higher education, and work status.
PENGARUH PEMBERIAN INFUSA DAUN KATUK (Sauropus androgynus (L) Merr) TERHADAP KADAR GLUKOSA DARAH MENCIT PUTIH (Mus musculus L) JANTAN YANG DIINDUKSI ALOKSAN Meiriza Djohari; Husnawati; Fina Aryani; Belia Sonali Bendre
Jurnal Penelitian Farmasi Indonesia Vol 12 No 1 (2023): JPFI
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (P3M) Sekolah Tinggi Ilmu Farmasi Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v12i1.1754

Abstract

Telah dilakukan penelitian tentang  pengaruh  infusa daun katuk  (Sauropus  androginus (L.) Merr) terhadap  kadar glukosa darah mencit putih (Mus musculus L.) jantan yang diinduksi aloksan. Penelitian ini bertujuan untuk melihat pengaruh  infusa  daun  katuk  terhadap  kadar  glukosa  darah  mencit  putih  jantan yang diinduksi aloksan 200mg/kgBB sebanyak 1% dari BB. Hewan percobaan dibagi menjadi 6 kelompok. Kelompok kontrol negatif diinduksi aloksan dan hanya diberi aquades, kelompok kontrol positif diberi glibenklamid dengan dosis 0,65mg/kggBB, kelompok normal diberi akuades dan pakan standar, kelompok perlakuan diberi sediaan infusa daun katuk dengan konsentrasi 10%, 20% dan 30%. 3 hari sebelum perlakuan mencit diinduksi aloksan terlebih dahulu dengan dosis 200mg/kgBB. Perlakuan dilakukan selama 15 hari  berturut-turut.  Kemudian diukur  kadar  glukosa darah  mencit  pada  hari ke-5,  10,  dan 15.  Berdasarkan  hasil pengujian infusa daun katuk pada konsentrasi 10%, 20% dan 30% dapat menurunkan kadar glukosa darah mencit putih jantan yang diinduksi aloksan, dan perlakuan yang paling efektif menurunkan glukosa darah mencit adalah pada konsentasi 30%. Hasil yang diperoleh dari hasil uji ANOVA satu arah dilanjutkan dengan uji Post Hoc Tukey juga menunjukkan bahwa lama pemberian infusa daun katuk dapat mempengaruhi penurunan kadar glukosa darah mencit (p<0,05). Research of the effect of katuk (Sauropus androginus (L.) Merr) leaves infusion on the blood glucose levels of alloxan-induced male white mice (Mus musculus L.) was performed. This study aims to investigate the effect of the infusion of katuk leaves on the blood glucose values of male white mice induced by 200 mg/kgBB alloxan to 1% of BW. Experimental animals were divided into 6 groups. The negative control group was induced by alloxan and received aquades only, the positive control group received glibenclamide in a dose o f 0.65 mg/kgBB, the normal group received distilled water and standard food, the treatment group received the preparation of katuk leaves infusion with a concentration of 10%, 20% and 30%. 3 days before the treatment of mice, alloxan first induced with a dose of 200 mg/kgBB. The treatment was carried out for 15 consecutive days. Then measured the blood glucose levels of mice on days 5, 10 and 15. Based on the test result, the katuk leaves infusion at concentrations of 10%, 20% and 30%, can decrease the blood glucose levels in alloxan-induced male white mice, and the most effective treatment to reduce blood glucose in mice is at a concentration of 30%. The results obtained from the one-way ANOVA test followed by the Post Hoc Tukey test also showed that the duration of administration could influence the decrease in blood glucose levels in mice (p <0.05).
Analisis Efektivitas Biaya Haloperidol-Klorpromazin dan Risperidon-Klozapin Pada Pasien Skizofrenia Berdasarkan Kualitas Hidup di Rumah Sakit Jiwa Tampan Propinsi Riau Fina Aryani; Septi Muharni; Nyimas Farastika Harsah
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 8, No 2 (2023)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v8i2.63153

Abstract

Skizofrenia merupakan penyakit gangguan otak parah yang membutuhkan terapi dengan waktu lama sehingga meningkatkan beban biaya dan mempengaruhi kualitas hidup. Penelitian ini bertujuan untuk mengetahui efektivitas biaya antipsikotik haloperidol-klorpromazin dan risperidon-klozapin terhadap kualitas hidup pasien skizofrenia. Jenis penelitian ini adalah observasional, bersifat deskriptif analitik secara cross-sectional menggunakan analisis farmakoekonomi yaitu Cost Effectiveness Analysis dengan perspektif penelitian adalah pasien. Pengambilan sampel dilakukan di Ruang Rawat Inap Rumah Sakit Jiwa Tampan Propinsi Riau menggunakan metode purposive sampling dengan jumlah sampel sebanyak 57 pasien, 29 pasien menggunakan haloperidol-klorpromazin dan 28 pasien menggunakan risperidon-klozapin. Kualitas hidup dinilai menggunakan kuesioner Schizophrenia Quality of Life Scale. Hasil penelitian didapatkan rata-rata biaya perbulan kelompok haloperidol-klorpromazin Rp. 2.771.551, sedangkan risperidon-klozapin Rp. 2.920.441, kualitas hidup pada kelompok haloperidol-klorpromazin 59,77% dan risperidon-klozapin 60,93% sehingga didapat nilai ACER kelompok haloperidol-klorpromazin Rp. 46.370 dan risperidon-klozapin Rp. 47.931. Berdasarkan uji statistik T tidak berpasangan diketahui tidak terdapat perbedaan kualitas hidup antara kedua kelompok dengan nilai p=0,717 (p<0,05), sehingga dapat disimpulkan bahwa kelompok haloperidol-klorpromazin lebih cost effective.
Formulation and Antioxidant Activity Test of Rice Bran Extract Cream from Two Varieties of White Rice Wira Noviana Suhery; Hayu Lestari; Armon Fernando; Fina Aryani; Gressy Novita
Majalah Obat Tradisional Vol 28, No 2 (2023)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.84715

Abstract

Rice bran extract contains high antioxidant compounds. Formulation and antioxidant activity testing of cream preparations containing rice bran extract has been carried out. This study aims to formulate and evaluate cream preparations containing bran extract from two varieties of white rice and their antioxidant activity. The white rice varieties used were the Kalpatali variety (FI) and the Rice 64 (FII) variety. There were three cream formulas, namely the basic formula (F0) and the formula containing rice bran extract with a concentration of 3.1% each (FI and FII). Evaluation of cream preparations included organoleptic test, homogeneity, pH, washability, stability, irritation test, and antioxidant activity test. This study showed that FI has an antioxidant activity of 87.23% and FII has an antioxidant activity of 64.08%. Different varieties of rice show differences in antioxidant activity in cream preparations containing bran extract. The best formula is FI which has good physical properties and higher antioxidant activity compared to FII. 
Gambaran Penggunaan Multivitamin selama Pandemi COVID-19 di Apotek Kota Pekanbaru Fina Aryani; Windi Sayuti Ningsih; Meiriza Djohari; Anugrah Humairah
Sinteza Vol. 4 No. 1 (2024): February
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v4i1.21051

Abstract

Tingginya kasus COVID-19, mengharuskan masyarakat untuk melakukan berbagai upaya preventif atau pencegahan, salah satu upaya yang dapat dilakukan adalah dengan menjaga imunitas tubuh yang dapat ditingkatkan dengan penggunaan multivitamin. Multivitamin mengandung beberapa vitamin dan mineral, kecukupan zat gizi terutama vitamin dan mineral sangat diperlukan dalam mempertahankan sistem kekebalan tubuh yang optimal. Penelitian ini bertujuan untuk mengetahui penggunaan multivitamin pada masyarakat di salah satu apotek Kota Pekanbaru selama pandemi COVID-19. Penelitian ini merupakan penelitian observasional yang bersifat deskriptif dengan teknik pengambilan data secara retrospektif. Populasi pada penelitian ini adalah data semua penjualan multivitamin selama pandemi Covid-19 dari bulan Maret 2020 hingga Juni 2021. Sampel adalah semua populasi sehingga teknik pengambilan sampel yang digunakan yaitu sampel jenuh. Data yang diambil adalah data sekunder berupa data penjualan multivitamin selama pandemi Covid-19 dari bulan Maret 2020 hingga Juni 2021. Hasil penelitian menunjukkan bahwa penjualan nama multivitamin yang paling banyak adalah Zegavit® sebanyak 10,41% dengan zat aktif Vitamin C sebesar 45,40%, bentuk sediaan multivitamin yang paling banyak terjual adalah tablet atau kaplet dengan persentase 68,16% dengan komposisi kombinasi sebesar 98,42%. Berdasarkan hasil penelitian disimpulkan multivitamin yang paling tinggi angka penjualannya yaitu multivitamin kombinasi dengan bentuk sediaan tablet.
REVIEW : ETNOBOTANI, TOKSISITAS, FITOKIMIA, DAN AKTIVITAS BIOLOGI DARI TUMBUHAN RENDA (Carissa carandas L) Fadhli, Haiyul; Difa, Faradini Ramsanjami; Frimayanti, Neni; Aryani, Fina
Jurnal Farmasi Udayana Vol. 12, No. 2, tahun 2023
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JFU.2023.v12.i02.p04

Abstract

Renda (Carissa carandas L.) is a plant in the Apocynaceae family with dichotomous branches and milky sap. The plant bears small, oval-shaped fruits that are green at first and turn reddish-purple as they ripen. This review aims to integrate the secondary metabolites and biological activities of Carissa carandas L while also providing the scientific evidence required for future research. Online and offline literature were used to review this article. Online literature is sourced from local and international journal publications from journal providers on the internet and from online literature in books and e-books. This article covers the ethnobotany, toxicity, secondary metabolite compounds, and biological activities reported through search engines such as Google Scholar, NCBI, PubMed, ScienceDirect, Research Gate, and Springer. Based on existing literature, Carissa carandas can help treat diabetes, hypertension, hepatoprotection, anticonvulsants, antimalarials, antioxidants, anthelmintics, diarrhea, and hyperlipidemia.
HUBUNGAN TINGKAT PENGETAHUAN OBAT GASTRITIS YANG DIIKLANKAN DI TELEVISI TERHADAP PERILAKU SWAMEDIKASI MASYARAKAT DI APOTEK SE-KECAMATAN BANGKINANG KOTA PROVINSI RIAU Aryani, Fina; Aryani, Soufie; Muharni, Septi
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 15 No. 2 (2023): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v15i2.138

Abstract

Gastritis is a condition where the production of acid in the stomach can cause irritation. To treat gastritis, patients can do self-medication (self-medication). The factors that influence self-medication are sources of information such as advertisements on television. Self-medication behavior requires knowledge so that treatment is safe and rational. The purpose of this study was to determine the relationship between knowledge of gastritis medicine advertised on television and self-medication behavior in pharmacies in Bangkinang District, Riau Province. The type of research is observational, descriptive analytic method with cross sectional design and data collection simultaneously. Sampling was done by purposive sampling in order to obtain a total sample of 110 respondents who met the inclusion criteria. The results of the statistical test obtained a p value < 0.05, which means that there is a relationship between knowledge of gastritis medicine advertised on television and self-medication behavior in pharmacies throughout Bangkinang District, Riau Province.
Pengaruh E-Booklet terhadap PengetahuanTenaga Kefarmasian dalam Pemberian Informasi Obat Tetes Mata Aryani, Fina; Tri Agustini, Tiara; Ramadhani, Zulfithri Mutiara; Muharni, Septi
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol 20, No 2 (2023)
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/jiffk.v20i2.8197

Abstract

Pelayanan swamedikasi merupakan praktek pelayanan yang tinggi dilakukan oleh tenaga kefarmasian, salah satunya pelayanan swamedikasi tetes mata. Hal ini menuntut peran apoteker dan TTK yang cukup tinggi, salah satunya dalam pemberian informasi obat. Tujuan penelitian ini untuk melihat pengaruh pemberian media edukasi e-booklet terhadap tingkat pengetahuan tenaga kefarmasian pada pemberian informasi obat swamedikasi tetes mata. Penelitian ini merupakan penelitian quasi-experimental: non-equivalent control group design menggunakan metode probability sampling dengan teknik pengambilan sampel secara cluster random sampling. Sampel pada penelitian ini merupakan 96 tenaga kefarmasian yang bekerja di apotek se-kota Pekanbaru. Data dianalisis dengan uji Mann Whitney dengan hasil yang signifikan pada kelompok perlakuan saat pre test dan post test dengan nilai p=0,001 (p
Self Medication Drugs During The Covid-19 Pandemic At Pharmacy Aryani, Fina; Amalia, Annisa Yuri; Djohari, Meiriza; Humairah, Anugrah
JURNAL PROTEKSI KESEHATAN Vol 13 No 2 (2024): JPK: Jurnal Proteksi Kesehatan
Publisher : Poltekkes Kemenkes Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36929/jpk.v13i2.846

Abstract

Corona Virus Disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-Cov2) with a high mortality rate. Self-medication is the behavior of taking self-medication based on a diagnosis of the symptoms of illness that occurs. This study aims to determine the profile of the use of self-medication drugs that are often used to treat symptoms similar to COVID-19 during the COVID-19 pandemic at the Pekanbaru City Pharmacy, Riau Province in the period of July 2021. The type of research is observational with a descriptive design and concurrent data collection. The population is the respondent who self-medicates in a pharmacy in Pekanbaru. The sample is 100 respondents who have met the inclusion criteria with a purposive sampling technique. The results showed that the most used drugs were for fever symptoms (27.8%), the most pharmacological class of drugs purchased by patients were antipyretics-analgesics (32.5%), the most used dosage forms were tablets (58, 7%). During the self-medication process, patients most often received information from health workers (35.4%). Based on gender, the most patients who self-medicated were women (56%), the age of the most patients was around 17-25 years (46%), while from the last education level the most patients were high school/equivalent (44%) with the type of work as private employees (48%). Drugs that are often purchased during the Covid-19 pandemic are analgesics-antipyretic.
UJI INHIBITOR ENZIM TIROSINASE EKSTRAK DAN FRAKSI DAUN KEDABU (Sonneratia ovata Backer) SECARA IN-VITRO Furi, Mustika; Ainun Alfatma; Rahma Dona; Armon Fernando; Fina Aryani; Rahayu Utami; Septi Muharni; Husnawati; Wira Noviana Suhery; Melzi Octaviani
Jurnal Ilmiah Manuntung Vol 8 No 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.529

Abstract

Kedabu leaves (Sonneratia ovata Backer) are known contain secondary metabolites, one of which is phenolic, flavonoid and antioxidant activity. Phenolic, flavonoids and antioxidant are known to inhibit the tyrosinase enzyme. The tyrosinase enzyme is involved in the process of melanogenesis which produces melanin. Melanin can cause hyperpigmentation. To prevent hyperpigmentation, tyrosinase inhibitors are needed. This study aimed to test the tyrosinase enzyme inhibitor in ethanol extract, n-butanol fraction, ethyl acetate fraction, n-hexane fraction of kedabu leaf (Sonneratia ovatta Backer) using L-tyrosine as a substrate. The method used to get ethanol extract using ethanol maceration, while some fractions are obtained using the fractionation method. The test was carried out using L-tyrosine and kojic acid as a positive control with absorption measurements using microplate reader at a wavelength of 492 nm. The results showed that the best tyrosinase inhibitory activity was produced by the ethyl acetate fraction with an IC50 value of 18,82 g/mL, followed by the n-butanol fraction with an IC50 value of 24,42 g/mL, and the n-hexane fraction with an IC50 value. 28,77 g/mL, ethanol extract with an IC50 value of 99,09 with a strong category for all samples compared with kojic acid as a positive control with an IC50 value of 30,09 g/mL.
Co-Authors agistia, nesa Agustini, Tiara Tri Ainun Alfatma Amalia, Annisa Yuri Anggraeni, Ica Winanda Anugerah Humairah Z Anugrah Humairah Armon Fernando Armon Fernando Aryani, Soufie Azmi Juniati Belia Sonali Bendre Desmalia, Desmalia Difa, Faradini Ramsanjami Ditta Heriani Eci Marlina Emma Susanti Emrizal Fadila Toha Fatmalia, Anggun Fitra Ramadhan Fitri Primawanty Furi, Mustika Ginta Rio Maranti Gressy Novita Haiyul Fadhli Hayu Lestari Hidayani, Yelly Humairah, Anugrah Husnawati Husnawati Husnawati Husnawati Husnawati Husnawati Husnawati Iriani, Revy Lovina Aldelyn Lukman Hakim Maimun, Nur Maimun, Nur Maysharah Mizanni Meiriza Djohari, Meiriza Melzi Octaviani Mifta Zur Rahma Mira Febrina, Mira Musyirna Rahmah Nst Mutia Liasari, Mutia Neni Frimayanti Ningsih, Yozi Fiedya Nofriyanti Nofriyanti Noveri Rahmawati Nurul fadillah, Nurul Nyimas Farastika Harsah Oelan Sari Putri Zulnandita Rahayu Utami Rahayu Utami Rahayu Utami Utami Rahma Dona Ramadhani, Zulfithri Mutiara Ratna Sari Dewi Ratna Sari Dewi Reni Zulfitri Ricardo, Nadira Atiqah Richa Afrianti Richa Afrianti, Richa Ruska, Shinta Liana Sari, Oelan Sari, Rinita Satibi Satibi Septi Muharni Septi Muharni Septi Muharni Septi Muharni Septi Muharni Septi Muharni reviewer Septia wenila Septy Amelia Rizki Rambe Shafira Al Fadhilah Shelly Puspa Anggraini Sherly Putri Arsila Siregar, Lisa Andriyani Sitanggang, Sarah Dianora Siti Nurul Anissa Sulastri Tania Tiara Efendi utia Liasari Vanisa, Septia Welny Noverianti Windi Sayuti Ningsih Wira Noviana Suhery Yelly Hidayani Yudina Awaliyah Harahap