Claim Missing Document
Check
Articles

Found 3 Documents
Search
Journal : Narra J

Global research profile on monkeypox-related literature (1962–2022): A bibliometric analysis Fajar Sofyantoro; Hendrix I. Kusuma; Sandro Vento; Marius Rademaker; Andri Frediansyah
Narra J Vol. 2 No. 3 (2022): December 2022
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v2i3.96

Abstract

The recent monkeypox or mpox outbreak has been a global concern. The present study evaluated the global research outputs, research trends, and topics of published research on monkeypox using a bibliometric approach. The Scopus database was searched for terms associated with "monkeypox" or "monkey pox" up until 19 November 2022. Maps and bibliometric indicators of the retrieved documents were shown and analyzed. A total of 1,422 documents were obtained from Scopus. Other than monkeypox, the most commonly used terms included epidemic, disease outbreaks, smallpox vaccine, and orthopoxvirus. In total, 90.3% of the documents were published between 2002 and 2022. The United States, the United Kingdom, and India were the top three countries in terms of productivity. Most of the institutions were from the United States. The International Journal of Surgery, the Journal of Medical Virology, and the Travel Medicine and Infectious Disease are some of the top journals currently publishing research on monkeypox. Tecovirimat, coronavirus disease 2019 (COVID-19), homosexuality, and pandemic are emerging topics related to monkeypox.
Global research profile on monkeypox-related literature (1962–2022): A bibliometric analysis Sofyantoro, Fajar; Kusuma, Hendrix I.; Vento, Sandro; Rademaker, Marius; Frediansyah, Andri
Narra J Vol. 2 No. 3 (2022): December 2022
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v2i3.96

Abstract

The recent monkeypox or mpox outbreak has been a global concern. The present study evaluated the global research outputs, research trends, and topics of published research on monkeypox using a bibliometric approach. The Scopus database was searched for terms associated with "monkeypox" or "monkey pox" up until 19 November 2022. Maps and bibliometric indicators of the retrieved documents were shown and analyzed. A total of 1,422 documents were obtained from Scopus. Other than monkeypox, the most commonly used terms included epidemic, disease outbreaks, smallpox vaccine, and orthopoxvirus. In total, 90.3% of the documents were published between 2002 and 2022. The United States, the United Kingdom, and India were the top three countries in terms of productivity. Most of the institutions were from the United States. The International Journal of Surgery, the Journal of Medical Virology, and the Travel Medicine and Infectious Disease are some of the top journals currently publishing research on monkeypox. Tecovirimat, coronavirus disease 2019 (COVID-19), homosexuality, and pandemic are emerging topics related to monkeypox.
Comparative analysis of hemotoxic, myotoxic, and inflammatory profiles of Calloselasma rhodostoma and Trimeresurus insularis venoms in mice Aphrodita, Adiva; Sentono, Diva N.; Yudha, Donan S.; Purwestri, Yekti A.; Nuringtyas, Tri R.; Raharjo, Slamet; Wahid, Isra; Rahmi, Sri N.; Wahyudi, Setyanto T.; Sofyantoro, Fajar
Narra J Vol. 5 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narraj.v5i2.1874

Abstract

Snakebite envenomation remains a significant medical concern, particularly in tropical regions where venomous snakes such as Calloselasma rhodostoma and Trimeresurus insularis are prevalent. Both venoms are known for their potent hemotoxic, myotoxic, and inflammatory effects, yet their differential impacts on systemic physiological pathways remain unclear. The aim of this study was to characterize the hematological, myotoxic, and inflammatory effects of C. rhodostoma and T. insularis venoms in a murine model and to explore their influence on systemic factors such as insulin-like growth factor 1 (IGF-1), which is critical for muscle repair and inflammation regulation. Mice were exposed to varying doses (20–100 µg) of C. rhodostoma and T. insularis venoms. Hematological parameters, muscle degeneration, inflammatory cell infiltration, and plasma IGF-1 levels were assessed to evaluate the venoms' systemic and local effects. Our data indicated that C. rhodostoma venom induced significant changes in blood coagulation, muscle edema, and inflammatory infiltration, with pronounced effects even at lower doses. Conversely, T. insularis venom showed a dose-dependent suppression of IGF-1 levels, highlighting its unique systemic impact. Both venoms caused severe muscle damage, characterized by structural disintegration and increased leukocyte infiltration, with C. rhodostoma eliciting a stronger inflammatory response at lower doses.Snakebite envenomation remains a significant medical concern, particularly in tropical regions where venomous snakes such as Calloselasma rhodostoma and Trimeresurus insularis are prevalent. Both venoms are known for their potent hemotoxic, myotoxic, and inflammatory effects, yet their differential impacts on systemic physiological pathways remain unclear. The aim of this study was to characterize the hematological, myotoxic, and inflammatory effects of C. rhodostoma and T. insularis venoms in a murine model and to explore their influence on systemic factors such as insulin-like growth factor 1 (IGF-1), which is critical for muscle repair and inflammation regulation. Mice were exposed to varying doses (20–100 µg) of C. rhodostoma and T. insularis venoms. Hematological parameters, muscle degeneration, inflammatory cell infiltration, and plasma IGF-1 levels were assessed to evaluate the venoms' systemic and local effects. Our data indicated that C. rhodostoma venom induced significant changes in blood coagulation, muscle edema, and inflammatory infiltration, with pronounced effects even at lower doses. Conversely, T. insularis venom showed a dose-dependent suppression of IGF-1 levels, highlighting its unique systemic impact. Both venoms caused severe muscle damage, characterized by structural disintegration and increased leukocyte infiltration, with C. rhodostoma eliciting a stronger inflammatory response at lower doses.
Co-Authors Abiyyi, Muhammad Hawi Qabus Adania, Baik Aisyah Aeniah, Siti Allimi, Hayu Swari Almunawar, Muhammad Fikri Ammaru Bisandyaloka Andri Frediansyah Andri Frediansyah, Andri Aphrodita, Adiva Aprilia Sufi Subiastuti Apriliyani, Tia Ardaning Nuriliani Arief Maulana Sabilillah Ariel Hananya Ariesti, Wiwin Ashfiya Hanif Hasnadewi Athira Nur Rahma Azmatun Fildzah Azzahira, Faiha Azka Bambang Retnoaji Chusnul Azhar Dewi, Umi Rosita Dimas, Abimanyu Dwi Eny Djoko Setyono Dwi Sendi Priyono Empra, Desi Eka Putri Fadhlurrohman, Galih Dzaky Ganies Riza Aristya Gizela Aulia Agustin Halim, Shuha Ma’muriyah Hendrix I. Kusuma Hendry Tri Sakti Saragih Hidayat, Rheina Faticha Asyamsa Himarosa, Rela Adi Ishana, Aurelia Araya Isra Wahid Joko Nugroho Wahyu Karyadi Karlina, Ina Khoiruddin Anshori Krisdiyanto Krisdiyanto Krisdiyanto, Krisdiyanto Kusuma, Hendrix I. Lathief Al Umami Lisna Hidayati, Lisna Maharesi, Chesa Ekani Marius Rademaker Mataram, Made Bagus Auriva Muhammad Ardillah Rusydan Muhammad Baihaqi Muhammad Budi Nur Rahman Muhammada, Khusnus Syifa Muliawati, Adina Mulyati Mulyati Nareta Defiani Nastiti Wijayanti Nasution, Nurlita Putri Bela Nata Dwi Annisa Nizma Nur Rachman Maulana Nurhidayah, Septika Nuringtyas, Tri R. Pradnya Paramita Primadian Adhi Wardana Purwestri, Yekti A. Pusparini, Nur Ainun Oktavia Rademaker, Marius Rahmi, Sri N. Ramadhani, Gilang Afif Setya Rarastoeti Pratiwi Rela Adi Himarosa Rela Adi Himarosa Rizky Nuryani Rohmah, Zuliyati Saeed, Faisal Safitri, Della Thasya Liona Sandro Vento Sari, Ria Vinola Septhya Saribu, Ruth Liananda Citra Dolok Senny Helmiati Sentono, Diva N. Septriani, Nur Indah Simanungkalit, Eben Ezer Slamet Raharjo Slamet Widiyanto Sritanjung, Opi Sudarisman Sudarisman Sukirno Sukirno Supraitno, Murtiadi Erlan Syafei, Dio Rachmaputra Syam, Adi Mazdi Ulfa, Siti Zakia Utami, Mia Vento, Sandro Wahyu Aristyaning Putri Wahyu Aristyaning Putri Wahyu Nursehan Wahyudi, Setyanto T. Wulandari, Mutiara Tri Yekti Asih Purwestri Yudha, Donan S. Zusrina, Laili Mufli