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All Journal Indonesian Journal of Chemistry Collaborative Medical Journal (CMJ) AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT JURNAL FARMASIMED (JFM) Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal Indah Sains dan Klinis Mejuajua Journal of Health and Medical Science Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Jurnal Pengmas Kestra (JPK) FARMASAINKES Jurnal Indah Sains dan Klinis Indonesian Journal of Science and Pharmacy
Debi Meilani
Institut Kesehatan Medistra Lubuk Pakam
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary Other

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Journal : Jurnal Indah Sains dan Klinis

 1 
Aktivitas Antibakteri Daun Kemangi (Ekstrak, Fraksi Kloroform, dan Fraksi n-Heksan) terhadap Staphylococcus aureus dan Eschericia coli Melati Yulia Kusumastuti; Debi Meilani; Suhendra Tawarnate
Journal of Indah Science and Clinic Vol. 2 No. 1 (2021)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i1.11

Abstract

Basil (Ocimum citriodorum Vis.) is a plant which is their leaves are commonly eaten as fresh vegetables and has many benefits. Basil leaves contains secondary metabolite compounds that have antibacterial activity such as flavonoids, tannins, saponins, alkaloids, and steroids. The purpose of this study was to known the antibacterial activity of some fractions of basil leaves against Escherichia coli and Staphylococcus aureus and see which fraction was more active.This research included extraction by maceration method using ethanol 96%, then ethanol extract was fractionated using n-hexane and chloroform, phytochemical screening, then tested for antibacterial activity against E. coli and S. aureus by using agar diffusion method. Phytochemical screening showed ethanol extract contained alkaloids, saponins, flavonoids, tannins and steroids; chloroform fraction contained alkaloids, flavonoids, saponins, and tannins; and n-hexane fraction contained steroids. The results of the antibacterial activity test showed ethanol extract and chloroform fraction had antibacterial activity. Meanwhile, n-hexane fraction did not have antibacterial activity. Concentration of 500 mg / ml of chloroform fraction and ethanol extract on S. aureus resulted inhibition zone around 24.67-26.90 mm. Furthermore, on E. coli produced 22.67-23.84 mm. Ethanol extract had higher antibacterial activity than the chloroform fraction against E. coli and S. aureus.
Formulasi dan Evaluasi Sediaan Sabun Padat Antiseptik Ekstrak Etanol Daun Kunyit Suprianto Suprianto; Sumardi Sumardi; Debi Meilani; Sri Rahayu
Journal of Indah Science and Clinic Vol. 3 No. 1 (2022)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.44

Abstract

The plant of findings turmeric (Curcuma longa) are often used as a traditional medicinal. The part of the turmeric plant that is often used is the rhizome. In addition to turmeric rhizome, turmeric leaves are also used as a flavoring dish. Among the benefits of turmeric leaves is as an antimicrobial. Soap is a surfactant used for washing and cleaning. Antiseptics are inhibitors for the growth and development of microorganisms that live on the surface of the body. The study was to determine which ethanol extract of turmeric leaves could be formulated into antiseptic solid soap preparations. This study used an experimental method, turmeric leaves were extracted with 70% ethanol. The formula made are 2.5%, 5%, 7.5%. The quality of the soap preparation was carried out by organoleptic tests, acidity, high foam and irritation. The results test showed that the solid soap did not have the aroma of turmeric leaves, the pH of the soap was 9.9-10.5; foam height with a concentration of 7.5% which is 7.3 cm; and solid soap preparations ethanol extract of turmeric leaves did not cause irritation. The extract of turmeric leaves can be formulated into solid soap preparations. It is recommended to add perfume to the formulation of solid soap preparations of turmeric leaf extract as an antiseptic.
Analisis Biaya Efektif Terapi Diare Pasien Rawat Inap RS Putri Hijau Medan Suprianto Suprianto; Muhammad Gunawan; Melati Yulia Kusumastuti; Sumardi Sumardi; Debi Meilani
Journal of Indah Science and Clinic Vol. 3 No. 1 (2022)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.46

Abstract

Diare ditandai ekskresi tinja cair dengan ulangan tiga kali atau lebih per hari, akibat infeksi saluran cerna karena makanan dan air terkontaminasi mikroorganisme, ataupun langsung dari manusia akibat rendahnya sanitasi. Penelitian ditujukan untuk mengetahui karakteristik pasien diare, pengobatan dan efektivitas biaya pengobatan di Rumah Sakit Putri Hijau Medan. Penelitian non eksperimental bersifat deskriptif dan retrospektif rekam medik pasien bagian keuangan sejak Juli-Desember 2018. Cost Effectiveness Analysis sebagai metode analisis biaya. Karakteristik pasien diperoleh perempuan 14 (46,670%) dan laki-laki 16 (53,33%). Efektivitas New Diatabs (92,30%) dan New Diatabs-Metronidazole (94,11%). Biaya terapi dengan New Diatabs Rp 1.547,771/pasien dan New Diatabs-Metronidazole Rp 1.562,590/pasien. Average cost effectiveness New Diatabs Rp. 190.345 dan New Diatabs-Metronidazole Rp 183.060, sehingga disimpulkan terapi cost effective adalah penggunaan kombinasi New Diatabs-Metronidazole dibandingkan New Diatabs
Uji Ekstrak Kulit Buah Mangga Arum Manis dalam Etanol pada Tumbuh Kembang Escherichia coli dan Salmonella typhi Mandike Ginting; Suprianto Suprianto; Siti Fatimah Hanum; Debi Meilani; Maya Sartika
Journal of Indah Science and Clinic Vol. 3 No. 2 (2022)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Antibacterial is a substance that can interfere with the growth or even kill bacteria by interfering with harmful microbial metabolites. The skin of the Harum Manis Mango (Mangifera indica L.var. arum sweet) contains flavonoid compounds which are known to have antibacterial activity. Objective: This study aimed to determine the antibacterial activity of the ethanol extract of Harum Manis Mango skin against the antibacterial activity of Escherichia coli and Salmonella typhi. Methods: The research method used in this study was the well diffusion method to determine the antibacterial activity of the ethanol extract of the Harum Manis mango skin Escherichia coli and Salmonella typhi using chloramphenicol 250 mg used as a comparison of antibacterial activity. Results: The results of the antibacterial activity of the ethanolic extract of Harum Manis mango skin against Escherichia coli showed the diameter of the inhibition zone as follows: 20% concentration (12.83 mm), 30% concentration (12.93 mm) and 40% concentration (13.91 mm), while against Salmonella typhi with a concentration of 20% (11.63mm), a concentration of 30% (12.5mm) and a concentration of 40% (13.5mm).Conclusion: The conclusion of this study is that the ethanol extract of the skin of the Harum Manis Mango (Mangifera indica L. var. arum sweet) has antibacterial activity against Escherichia coli and Salmonella typhi bacteria. The most effective concentration against Escherichia coli at concentration of 40% (13.91mm) and Salmonella typhi at a concentration of 40% (13.5mm) with strong inhibition.
Co-Authors Adek Chan Ahmad Hafizullah Ritonga Alam Suhada Aminah Syarifuddin Ancel Mus Silaban Andraini, Galuh Ardiani, Rani Aritonang, Barita Ayu Khairunnisa Chan, Adek Cucu Arum Dwi Cahya Cut Fatimah Cut Fatimah Cyndi Veronica Dea Anggreini Deliwarni Rajagukguk Dewi Kartika Dian Zulkarnain Lubis Dicky Yuswardi Wiratma Dinda Sari Utami Effendy De Lux Putra Elvy Oktima Ernawaty Ginting Eva Sartika Dasopang Fatimah Sari Simatupang Febriady, Andy Fesri Damai Riang Laia Gabena Indrayani Dalimunthe Gusliani Eka Putri Harahap, Hasni Yaturramadhan Hasni, Hasni Yaturramadhan Harahap Herlina . Joko Wibowo Karnirius Harefa Khairiah, Khairiah Lidiya Sasmaita Sihotang Lubis, Minda Sari Mandike Ginting Mandike Ginting Maya Sartika Maya Sartika Melati Yulia Kusumastuti Melati Yulia Kusumastuti Miranda, Novia Anisa Muhammad Gunawan Muhammad Gunawan Nasirah Maulidia Ajhar Nasution, Lely Fitri Handayani Rafita Yuniarti Rahmi, Sofia Regina Elyanda Tampubolon Reni Aprinawaty Sirait Riza Hasyati Rotua Sumihar Sitorus Samran, Samran Siahaan, Enzo W.B Sitepu, Rahmadani Siti Fatimah Hanum Siti Nurbaya Siti Rahmi Ningrum Sofyan Syarifuddin Sri Rahayu SRI RAHAYU Suhendra Tawarnate Suhendra Tawarnate Suhendra Tawarnate Sumardi Sumardi Sumardi . Supran Hidayat Sihotang Suprianto Suprianto Syarifah Nadia Syarifuddin, Shofian Wibman Tambunan Yaturramadhan, Hasni Yessy Febriani Yosi Darmirani