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All Journal Jurnal Kesehatan Jurnal Sains dan Teknologi Farmasi Biology, Medicine, & Natural Product Chemistry Martabe : Jurnal Pengabdian Kepada Masyarakat Jurnal Farmasi Higea Khazanah Intelektual Poltekita: Jurnal Pengabdian Masyarakat Aptekmas : Jurnal Pengabdian Kepada Masyarakat Medical Sains : Jurnal Ilmiah Kefarmasian Indonesian Journal of Chemical Studies (Indones. J. Chem. Stud.) Jurnal Inovasi Pengabdian dan Pemberdayaan Masyarakat Riset Informasi Kesehatan Jurnal Pengabdian Harapan Ibu (JPHI) Medical Sains : Jurnal Ilmiah Kefarmasian
Rizky Yulion
Program Studi Farmasi, Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi
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Penyuluhan cara pengolahan tanaman obat lokal berbasis kearifan daerah di Pondok Pesantren Jamalul Qur’an Jambi Aisa Dinda Mitra; Medi Andriani; Mukhlis Sanuddin; Rizky Yulion
Jurnal Pengabdian Harapan Ibu (JPHI) Vol 4 No 2 (2022): Jurnal Pengabdian Harapan Ibu (JPHI)
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (723.555 KB) | DOI: 10.30644/jphi.v4i2.702

Abstract

Potensi dari pengobatan tradisional di wilayah Jambi sudah cukup memadai, meskipun pengetahuan yang berhubungan dengan hal ini penting untuk diketahui. Cara pengolahan juga menjadi faktor penting pemanfaatan potensi dari obat tradisional yang akan dijadikan obat oleh warga sekitar. Tempat pelaksanaan kegiatan yang bertempat di pondok pesantren jamalul qur’an jambi yang terletak di daerah muaro jambi. Didapatkan antusias warga yang menjadi peserta diskusi selama kegiatan berlangsung. Kegiatan penyampaian penyuluhan tentang cara pengolahan tanaman obat meliputi cara sederhana yang mungkin untuk dilakukan peserta untuk melakukan pengolahan obat tradisional sekitar yang berpotensi untuk digunakan sebagai pengobatan. Informasi jenis tumbuhan yang berkhasiat obat dengan sumber empiris menjadi hal yang penting untuk diketahui sebelum dilakukannya proses pengolahan obat tradisional yang akan dijadikan obat. Melihat lebih jauh terkait hal itu, ternyata banyak sekali tumbuhan yang belum diketahui nama dan kegunaannya sehingga sering kali dianggap sebagai tumbuhan pengganggu. Dengan peserta mengetahui jenis tumbuhan yang berpotensi sebagai obat dan mengetahui tentang cara pengolahannya, contohnya infusa dan dekokta. Maka potensi tersebut akan lebih bermanfaat lagi akan dirasakan manfaatnya oleh para warga.
UJI TOKSISITAS AKUT LD50 EKSTRAK BATANG BAJAKAH TAMPALA (Spatholobus littoralis Hassk.) DAN BATANG BAJAKAH KUNING (Arcangelisia flava (L.) Merr.) PADA MENCIT PUTIH (Mus musculus): ACUTE TOXICITY TEST LD50 OF BAJAKAH TAMPALA STEMP EXTRACT (Spatholobus littoralis Hassk.) AND YELLOW BAJAKAH (Arcangelisia flava (L.) Merr.) ON WHITE MICE (Mus musculus) Lili Andriani; Rizky Yulion; Olin Santia Manora; Regita Brilian Nanda
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 1 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i1.537

Abstract

Batang bajakah tampala (Spatholobus littoralis Hassk.) dan bajakah kuning (Arcangelisia flava (L.) Merr.) merupakan suatu tanaman yang sering digunakan oleh masyarakat Kalimantan secara empiris tujuan pengobatan secara tradisional. Kajian ilmiah batang bajakah tampala dan bajakah kuning telah mulai untuk diteliti lebih jauh. Namun kajian tentang keamanan penggunaannya masih belum dilakukan, sehingga perlu dilakukan uji toksisitas. Tujuan dilakukannya penelitian ini untuk menentukan nilai LD50 menggunakan persamaan dalam metode Farmakope Indonesia Edisi III pada pemberian batang bajakah tampala dan bajakah kuning serta mengetahui pengaruhnya pada bobot organ paru-paru, jantung, lambung, ginjal, dan hati terhadap variasi dosis dan jenis kelamin. Penelitian ini bersifat eksperimental dengan menggunakan mencit putih (Mus musculus) jantan dan betina sebanyak 50 ekor dan terbagi menjadi 5 kelompok. Kelompok kontrol diberi suspensi Na CMC 1% dan kelompok perlakuan diberi ekstrak batang bajakah tampala dan bajakah kuning dengan dosis 625 mg/kgBB, 1.250 mg/kgBB, 2.500 mg/kgBB, dan 5.000 mg/kgBB dengan sekali pemberian secara oral kemudian diamati setelah 24 jam dengan melihat jumlah kematian dan menghitung nilai rasio bobot organ. Hasil peneltian menunjukkan tidak ada kematian hewan uji sehingga dinyatakan dengan LD50 semu dan termasuk kategori praktis tidak toksik. Hasil uji statistik menunjukkan adanya perbedaan antara jenis kelamin dengan bobot organ pada paru-paru, lambung, dan hati serta tidak ada perbedaan antara variasi dosis dengan bobot organ pada paru-paru, jantung, lambung, ginjal, dan hati sehingga batang bajakah tampala aman digunakan. Kata kunci : Bajakah tampala (Spatholobus littoralis Hassk.), bajakah kuning (Arcangelisia flava (L.) Merr.), toksisitas akut, LD50 semu
FORMULATION AND IMMUNOMODULATORY BIOACTIVITY TEST OF NANOPARTICLE SYRUP OF ETHANOL EXTRACT OF SUNGKAI LEAVES (Peronema canescens Jack) Haflin; Agusriani; Kartika Mustofa; Ruri Putri Mariska; Rizky Yulion; Pitriani; Shafira Al Fadhilah; Barmi Hartesi
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 1 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i1.936

Abstract

Sungkai plants are beneficial immunomodulators because of the presence of flavanoid compounds that increase oxygen radicals and antibody production. Pharmaceutical preparations function as immunomodulators, typically in the form of syrups, tablets, capsules, suspensions, and emulsions. Until now, there has been no nanoparticle syrup on the market, even though nanoparticle preparations have the advantage of modifying particle size, controlling the release of active ingredients to reach the active side, protecting drugs from degradation, reducing toxicity, and minimizing side effects. The purpose of this study was to determine whether the syrup of nanoparticles in the ethanol extract of Sungkai leaves acts as an immunomodulator and the stability of the preparation during storage. The methods used were experimental in the laboratory with extraction using the maceration method. The extract obtained was formulated into a nanoparticle solution using the ionic gelation method, then formulated into FO syrup (Base syrup) and F1 syrup (Nanoparticles of ethanol extract of sungkai leaves) and then carried out transmittance tests, particle size analyzer tests, immunomodulatory tests and stability tests. The yield of the extract was 17.5%. The raw material examination of all the materials was in accordance with the literature. The particle size of the nanoparticle solution was 40 nm, that of F0 syrup was 670 nm, and that of F1 syrup was 964 nm. All syrup preparations fell into the nanoparticle size category of 10–1,000 nm. The leukocyte count of the negative control treatment (syrup base) was 5,011 cells/mm³, ...
Spray Gel Formulation of Ethanolic Extract Senduduk Leaves (Melastoma malabatricum) Against Antioxidant Activity, SPF, and Chemical Components Analysis with LC-MS/MS Yulion, Rizky; Andriani, Lili; Asadi, Henityo Agung; 'Aliyah, Siti Hamidatul; Mariska, Ruri Putri; Perawati, Santi; Hasanah, Rifdatul
Indonesian Journal of Chemical Studies Vol. 2 No. 2 (2023): Indones. J. Chem. Stud., December 2023
Publisher : Indonesian Scholar Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55749/ijcs.v2i2.37

Abstract

Senduduk leave (Melastoma malabathricum) is one of the species in the melastomaceae family that has long been used by local Indonesian people, one of which is the Suku Anak Dalam (SAD) for various needs and also as traditional medicine. The study aimed to examine the antioxidant activity of ethanolic extract of senduduk leaves. The extract was then formulated into spray gel preparations as UV-B sunscreen. The research method used was starting from sampling, determination, making samples, soxhlet, determining the IC50 value, spray gel preparation formulation, formulation stability test, measuring sun protection factor (SPF) values, and identifying extract chemical components with the LC-MS/MS instrument. The results was that the ethanolic extract of senduduk leaves had an IC50 value of 49.73 μg/mL with the best SPF value at a concentration of 70 ppm, which is 19.98. Spray gel preparations with a concentration of 70 ppm have an IC50 value of 44.22 μg/mL, an SPF value of 24.96, and a potent antioxidant intensity. So, extract spray gel can potentially have activity as antioxidants and can be used as UV-B sunscreen. The compounds identified include quercetin, quercitrin, DEET, n-boc-3-pyrrolidinone, medicarpine, taxinine, and other compounds. The ethanol extract of the soxhlet results showed more promising results for further tests of in-vitro, in-vivo, and in-silico bioactivity studies.
STUDI ETNOFARFARMASI PADA SUKU ANAK DALAM (SAD) DI DESA PEMAYONGAN KECAMATAN SUMAY KABUPATEN TEBO PROVINSI JAMBI: STUDI ETNOFARFARMASI PADA SUKU ANAK DALAM (SAD) DI DESA PEMAYONGAN KECAMATAN SUMAY KABUPATEN TEBO PROVINSI JAMBI Perawati, Santi; Sutrisno, Deny; Ara Ofiana; Deny Sutrisno; Siti Hamidatul 'Aliyah; Lili Andriani; Rizky Yulion Putra; Rahmadevi; Desi Sagita; Yuni Andriani; Lia Anggresani; Barmi Hartesi
Jurnal Khazanah Intelektual Vol. 7 No. 2 (2023): Khazanah Intelektual
Publisher : Balitbangda Provinsi Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37250/khazanah.v7i2.198

Abstract

Background : Suku Anak Dalam is one of the tribes in Indonesia who still upholds their customs and culture, including their local knowledge about medicine using medicinal plants. One of the Suku Anak Dalam community lives in Pemayongan Village, Tebo Regency, Jambi Province. This ethnopharmaceutical research was conducted to find out various diseases experienced by Suku Anak Dalam and to know various natural resources that are used as treatment. Method : This type of research is a descriptive study using qualitative methods and sampling techniques, namely snowball sampling through open-ended interviews with informants. Results: The results of the study stated that diseases that was often experienced by the Suku Anak Dalam included fever, coughing, itching, shortness of breath and abdominal pain. Treatment of the disease by utilizing natural resources in the form of plants and animals. Plant parts used are roots, leaves, bark, and fruit sap, while for animals the parts used are fat, scales, and meat. The processing method is scraped, crushed, boiled, fried, while the use of these ingredients is eaten, drunk, and applied to the affected part. Conclusion : Based on the results of research that has been done there are 5 diseases that often occur and there are 9 kinds of plants and 5 animals that are used as traditional medicine. Keywords : Ethnopharmacy, Disease, Jambi, Suku Anak Dalam, Natural Resources
Quercetin Bioavailability Evaluation on Standardized Herbal Medicine Containing Guava Leaf Extract with HPLC Yulion, Rizky; Yulianis, Yulianis; Suntri, Suntri
Biology, Medicine, & Natural Product Chemistry Vol 12, No 2 (2023)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2023.122.593-599

Abstract

Standardized herbal medicines are classified as one of Indonesia's natural medicine ingredients in addition to herbal medicine and phytopharmaceuticals. The safety and efficacy of standardized herbal medicines are scientifically proven through preclinical trials, and raw materials and products have been standardized. One includes standardized herbal medicines is diapet, psidii, lelap, fitolac, and glucogarp. To determine the bioavailability of standardized herbal products containing guava leaf extract (Psidium guajava L.). which uses single and combined natural materials. The method used is experimental with a crossover design. Blood samples are taken from the marginalis vein of the rabbit ear at 0.5 hours; 1; 2; 4; and 6. The level of quercetin in the blood is determined by the reverse-phase HPLC method. The mobile phase used is methanol:aquabidest (59:41,v/v), stationary phase octadecyl silica (C18), flow rate 1 mL/min, UV-Vis detector 370 nm, and injection volume 20 ?L. The value of bioavailability parameters obtained in the parameters Cpmax, Tmax, and AUC of product A is 1.486454 ?g / ml; 1.4 hours and 10.2615291 ?g/ml/h, product B is 1.29224019 ?g/ml; 1.5 hours and 11.30810501 ?g/ml/hour. Based on the results of this study, it can be concluded that the bioavailability profile of the two products is not much different, so it is expected that the effects caused are the same.
Pemanfaatan Bahan Alam untuk Pemeliharaan Kesehatan di Desa Seleman Kecamatan Danau Kerinci Rizky Yulion Putra; Anggraini, Gusnia; Ridha, M Sa'id; Fitri, Nadia; Nurfazila, Nurfazila; Rahmadina, Rahmadina; Kholilawati, Nelly; Sari, Wanti Puspita
Poltekita: Jurnal Pengabdian Masyarakat Vol. 4 No. 3 (2023): Juli-September
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/pjpm.v4i3.2024

Abstract

Health problems are still the main problems in Seleman Village, including diabetes, hyperlipidemia, gout, myalgia, and hypertension. This community service aims to improve the health and knowledge of residents in using medicine correctly and can utilize herbal plants as alternative treatments that can also be used as business opportunities. The methods used are counseling and demonstration as well as giving leaflets/brochures. This activity was carried out in the Seleman Village area. The target of counseling is the residents of Seleman Village with a total of 161 residents. From the pre-test results, 49.3% knew about hypertension, 40.42% knew about cholesterol, 56.78% knew about diabetes, and 51.87% knew about gout. After conducting educational activities about the disease, 95.34% knew about hypertension, 97.34% knew about cholesterol, 96.55% knew about diabetes, and 96.44% knew about gout. It can be concluded that from the community service carried out there is an increase in public knowledge on how to use medicine and independent use of herbal plants as alternative treatments derived from nature or known as "back to nature".
Co-Authors 'Aliyah, Siti Hamidatul Achmad Noerkhaerin Putra Agus Evendi Agusriani, Agusriani Ahmad Rozan Dewansyah Aisa Dinda Mitra Andriani, Medi Anggraini, Gusnia Anggresani, Lia Ara Ofiana Atika Kurniawati Barmi Hartesi Debora Dwi Hardiyanti Desi Sagita Dinda Melvia Feranika Manik Fitri, Nadia Fresha Nurmayora Haflin Harrizul Rivai Hasanah, Rifdatul Hayatul Rahmi Hayatul Rahmi Helmi Arifin Jheni Ramayanti Utami Kartika Mustofa Kholilawati, Nelly Kiki Reski Ulandri Krisyanella Krisyanella Lara Syahila Lesra Indriani Lia Anggresani Lili Andriani Lili Andriani Lili Andriani Linda Hevira M. Henityo Agung As'adi Nadia Monika Nike Nur Ahdiyah Nurfazila, Nurfazila Nurinayah Nurinayah Olin Santia Manora Oliyen Madori Pitriani Rahma Anggun Suciati Rahmadevi Rahmadina, Rahmadina Regina Amanda Regita Brilian Nanda Regita Brilian Nanda Retno Agustia Ningsih Ridha, M Sa'id Rohadi Ramlan Ruri Putri Mariska Santi Perawati Santi Perawati Santi Perawati, Santi Perawati, Santi Sanuddin, Mukhlis Sari, Wanti Puspita Sella Julia Ananda Shafira Al Fadhilah Siti Hamidatul 'Aliyah Suci Ramadani Suhatri Suhatri Suntri, Suntri Supriadi Supriadi Suryani Suryani Sutrisno , Deny Tirto Agung Pangestu Tita Aulya Novira Wely Yantari Yantari, Wely Yollanda N urulita Yulianis Yulianis Yuliawati Yuliawati Yuni Andriani