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Literature Review of COVID-19 Antivirus Activities Bioactive Compounds and Herbal Plant Extracts Yulianis, Yulianis; Yulion Putra, Rizky; Putri Agustina, Nadiva
Jurnal KESANS : Kesehatan dan Sains Vol 2 No 12 (2023): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v2i12.227

Abstract

Introduction: Currently the world is being hit by a virus outbreak that causes symptoms of pneumonia, on December 31, 2019 China reported a mysterious case of pneumonia with no known cause. Objective: The purpose of this study was to look at bioactive compounds and extracts that have the potential as COVID-19 antivirals. Method: This research is a literature study derived from the PubMed and Science Direct databases using the Preparred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) method. Result and Discussion: In the results of the literature review, 22 articles were found that entered the inclusion criteria. The average extracts and compounds in pre-clinical data showed a very strong IC50 value with a value of <50 ug/ml, while in clinical trials, herbal plant products showed that they were anti-inflammatory and immunomodulatory. Conclusion: So, it can be concluded that natural product products from herbal plants have the potential as an antiviral for COVID-19
The Ethanol Extract Fractionation (Peperomia Pellucida (L.) Kunth) On Uric Acid Levels Blood Serum Of Male White Mice Hevira, Linda; Yulion Putra, Rizky; Suciati, Rahma Anggun
JURNAL FARMASI GALENIKA Vol 10 No 3 (2023): Jurnal Farmasi Galenika Vol 10 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v10i3.278

Abstract

Research has been carried out on the effect of fractionating the ethanol extract of the messenger herbs (Peperomia pellucida (L.) Kunth) to reduce blood serum uric acid levels in male white mice. Ordered herbs containing flavonoid compounds are thought to be used as lowering uric acid levels in the blood. The purpose of this study was to determine the effect of giving the ethanol extract fraction (Peperomia pellucida (L.) Kunth) on blood serum uric acid levels of male white mice. Simplicia extraction was carried out with 96% ethanol and extract fractionation was carried out using n-hexane, ethyl acetate, and water as solvents. The chicken liver inductor was used using experimental methods in vivo. Uric acid levels in mice were measured using a test-strip out. The results of the analysis using statistical tests on the decrease in uric acid levels in the blood were significant with a value (p 0.05) on the 14th day of the ethyl acetate fraction. This study concludes that there are compounds in the messenger herbs that have the potential to reduce uric acid levels in the blood.
Edukasi Logo Obat, Dagusibu dan Bud Serta Cek Kesehatan Guru Yulion, Rizky; Mitra, Aisa Dinda; Asadi, Henityo Agung; Amanda, Regina; Gunawan, Indra; Dewansyah, Ahmad Rozan; Novira, Tita Aulya
Jurnal Abdimas Kesehatan (JAK) Vol. 6 No. 1 (2024): Januari
Publisher : Universitas Baiturrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36565/jak.v6i1.657

Abstract

Community service activities were carried out at SMA N 1 Muaro Jambi with the educational theme of drug logos, dagusibu, and Beyorn Use Date (BUD) as well as free health checking activities for educators at SMA N 1 Muaro Jambi. The topic was raised to provide education delivery to respondents with formal education and is expected to have a positive impact on the surrounding location. The topic also supports the program of the Central Board of the Indonesian Pharmacists Association (PP-IAI). This activity was carried out by making 10 questions designed that referred to the theme and topic of the activity consisting of pre-test and post-test, the next data was carried out through statistical tests using Paired T-tests. Tangible differences were obtained in respondents who received educational exposure (P<0.05). With data on 23 respondents, There is an increase in the educational value of respondents on community service materials. These results also confirm the understanding of the material educational theme of drug logos, dagusibu, and Beyorn Use Date (BUD) provided to respondents. In the Health examination, information was obtained, the respondents suffered from health problems as evidenced by the results of health checks, especially on blood pressure. In conclusion, education on pharmacy topics obtained satisfactory results for high school students
Pengaruh PIO Dengan Dan Tanpa Media Leaflet Terhadap Tingkat Kepatuhan Minum Obat Pasien Hipertensi Di Puskesmas X Kabupaten Batanghari Nurhidayanti, RTS. Reni; Hadriyati, Armini; Yulion, Rizky
Jurnal Pharmacopoeia Vol 3 No 2 (2024): September 2024
Publisher : Poltekkes Kemenkes Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33088/jp.v3i2.863

Abstract

Kepatuhan minum obat sering menjadi kendala bagi pasien dengan penyakit kronis salah satunya adalah hipertensi karena akan mengkonsumsi obat seumur hidup dengan terkontrol. Tujuan penelitian ini untuk mengetahui pengaruh pemberian informasi obat (PIO) dengan dan tanpa media leaflet terhadap kepatuhan minum obat pasien hipertensi rawat jalan di Puskesmas X Kecamatan Batin XXIV Kabupaten Batanghari. Penelitian ini adalah jenis kuantitatif, desain quasi eksperimen dengan rancangan pretest-posttest control grup design. Data diambil secara prospektif dan diukur tingkat kepatuhannya dengan kuesioner MMAS-8 (Morisky Medication Adherence Scale). Hasil analisis memperlihatkan bahwa pemberian informasi obat tanpa media leaflet, dengan uji wilcoxon diperoleh tidak ada pengaruh peningkatan kepatuhan yang signifikan dengan p-value 0.138 (P>0.05) sedangkan hasil dari pemberian informasi obat dengan media leaflet adanya pengaruh peningkatan kepatuhan yang signifikan dengan p-value 0.000 (P<0.05). Kesimpulan penelitian ini adalah pemberian informasi dengan media leaflet berpengaruh dalam meningkatkan kepatuhan minum obat dibandingkan pemberian informasi tanpa media leaflet terhadap pasien hipertensi. 
Pengaruh Pelayanan Informasi Obat Tb Paru Dengan Media Audio Visual Terhadap Tingkat Pengetahuan Pengawas Menelan Obat (PMO) Tuberculosis Paru Di Puskesmas X Di Kota Jambi Putra, Rizky Yulion; Sutrisno, Deny; Munti, Putri Delina Cupa
Jurnal Pharmacopoeia Vol 3 No 2 (2024): September 2024
Publisher : Poltekkes Kemenkes Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33088/jp.v3i2.864

Abstract

Kejadian tuberkulosis masih menjadi permasalahan di Indonesia. Keberhasilan penyembuhan tuberkulosis sangat tergantung pada kepatuhan penderita dalam minum obat. Supaya penderita patuh, pengawas menelan obat (PMO) wajib mempunyai pengetahuan yang baik tentang tuberkulosis. Riset ini bertujuan buat mengenali pengaruh pelayanan data obat TB paru lewat media audio visual terhadap tingkatan pengetahuan PMO TB Paru di Puskesmas X Kota Jambi. Desain riset yang digunakan merupakan kuantitatif dengan pendekatan Quasi- eksperimental. Riset dilaksanakan di Puskesmas X Kota Jambi pada bulan Mei hingga Juni 2024. Sampel penelitian terdiri dari 35 orang PMO yang dipilih. Rata-rata skor pengetahuan sebelum pemberian informasi obat TB paru melalui media audio visual adalah 17,31 dan meningkat menjadi 19,74 setelah intervensi. Analisis bivariat menemukan adanya pengaruh signifikan dari pemberian informasi obat melalui media audio visual terhadap pengetahuan PMO TB Paru di Puskesmas X Kota Jambi( p- value=0, 000). Bersumber pada hasil riset bisa disimpulkan kalau pemberian data obat lewat media audio visual efisien tingkatkan pengetahuan PMO TB Paru. Diharapkan Puskesmas menggunakan media audio visual dalam edukasi tuberkulosis kepada masyarakat.
Pemanfaatan Bahan Alam untuk Pemeliharaan Kesehatan di Desa Seleman Kecamatan Danau Kerinci Rizky Yulion Putra; Anggraini, Gusnia; Ridha, M Sa'id; Fitri, Nadia; Nurfazila, Nurfazila; Rahmadina, Rahmadina; Kholilawati, Nelly; Sari, Wanti Puspita
Poltekita: Jurnal Pengabdian Masyarakat Vol. 4 No. 3 (2023): Juli-September
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/pjpm.v4i3.2024

Abstract

Health problems are still the main problems in Seleman Village, including diabetes, hyperlipidemia, gout, myalgia, and hypertension. This community service aims to improve the health and knowledge of residents in using medicine correctly and can utilize herbal plants as alternative treatments that can also be used as business opportunities. The methods used are counseling and demonstration as well as giving leaflets/brochures. This activity was carried out in the Seleman Village area. The target of counseling is the residents of Seleman Village with a total of 161 residents. From the pre-test results, 49.3% knew about hypertension, 40.42% knew about cholesterol, 56.78% knew about diabetes, and 51.87% knew about gout. After conducting educational activities about the disease, 95.34% knew about hypertension, 97.34% knew about cholesterol, 96.55% knew about diabetes, and 96.44% knew about gout. It can be concluded that from the community service carried out there is an increase in public knowledge on how to use medicine and independent use of herbal plants as alternative treatments derived from nature or known as "back to nature".
Antioxidant activity and gel formulation of Areca catechu fractionation Supriadi, Supriadi; Brata, Andy; Yuliawati, Yuliawati; Yulion, Rizky; Purwantiningsih, Purwantiningsih
Riset Informasi Kesehatan Vol 13 No 2 (2024): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/rik.v13i2.883

Abstract

Ultrasonic NaDES-based optimization of luteolin extraction technology from celery (Apium graveolens) for improved drug raw material independence Putra, Rizky Yulion; Mariska, Ruri Putri; Latifah, Putri Ningrum Nurin
Riset Informasi Kesehatan Vol 13 No 2 (2024): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/rik.v13i2.906

Abstract

Background: Natural deep eutectic solvents (NaDES) represent a significant advancement in the field of natural material extraction, offering a novel approach to the isolation of active compounds. The objective of this study was to develop a novel NaDES-based extraction method to achieve the highest percentage of luteolin compounds in celery (Apium graveolens) through ultrasonic treatment. Method: Choline chloride was employed as the hydrogen bonding acceptor (HBA), while lactic acid and malic acid served as the hydrogen bonding donors (HBD). Treatment optimization was conducted using Design Expert 7 software, with the variables comprising the HBA:HBD ratio, temperature, and time. Results: The optimal combination of NaDES solvents was identified as choline chloride: lactic acid and choline chloride: malic acid at a ratio of (4.71 mol: 4.76 mol) and (1.27 mol: 1.71 mol), respectively, at a temperature of 55.2°C. The optimal conditions were 40°C and 35.45°C, with a time of 15.63 minutes and 12.73 minutes, respectively, which yielded 2.2789% and 0.0102% with a desirability of 0.2788 and 0.0408, respectively. Conclusion: The optimal combination was identified as choline chloride: lactic acid, which demonstrated a gain of over 2%. Additionally, the combination of choline chloride: malic acid proved effective for luteolin extraction.
STRATEGI HOLISTIK PEMBERDAYAAN MASYARAKAT DESA SUNGAI PUAR DALAM MENGATASI PENYAKIT DEGENERATIF DENGAN MEMBERIKAN EDUKASI TENTANG PENGGUNAAN OBAT HERBAL TOGA Yulion, Rizky; Pangaribuan, Ribka; Monica, Bunga; Fahreza4, Zami; Hafizah, Nurhafni; Permata, Intan; Biodola, Anggun; Aprilia, Laurenc
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 7, No 5 (2024): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v7i5.1616-1624

Abstract

Desa Sungai Puar: Meningkatkan Pengetahuan Kesehatan Masyarakat Desa Sungai Puar di Jambi, didirikan tahun 1885, dengan 250 penduduk yang memiliki beragam mata pencaharian. Program kesehatan di desa ini fokus pada 5 penyakit utama: infeksi saluran pernapasan atas, diabetes, asam urat, hipertensi, dan TBC. Program ini memberikan pengetahuan tentang penyakit, pencegahan, pengobatan alternatif, dan hidup sehat. Program ini juga meningkatkan pengetahuan tentang pencegahan stunting dan penyakit lainnya, melibatkan siswa SD dalam belajar tentang kebersihan, profesi apoteker cilik, dan makanan modern sehat untuk mencegah stunting. Program ini juga memberikan edukasi kepada ibu-ibu pengajian tentang penggunaan obat antibiotik yang tepat dan obat tradisional. Masyarakat dilibatkan dalam penanaman tanaman obat keluarga dan mendapatkan pemeriksaan kesehatan gratis (gula darah, tekanan darah, asam urat, kolesterol). Hasilnya, program ini meningkatkan pengetahuan masyarakat tentang kesehatan, mencegah penyakit dan stunting, dan menghasilkan masyarakat yang lebih sehat.
PEMANFAATAN TANAMAN TRADISIONAL SEBAGAI ALTERNATIF PENGOBATAN DI RT 21 DAN RT 23 DESA MEKAR JAYA KECAMATAN SUNGAI GELAM Yulion, Rizky; Nurinayah, Nurinayah; Ramayanti Utami, Jheni; Brilian Nanda, Regita; Melvia, Dinda; Agung Pangestu, Tirto
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 5, No 6 (2022): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v5i6.2053-2058

Abstract

Tanaman obat yang terdiri dari daun, akar, buah, kayu dan umbi-umbian telah digunakan sejak lama oleh masyarakat. Sampai saat ini masyarakat percaya dengan pengobatan yang berasal dari bahan alam atau dikenal dengan istilah “Back To Nature”. Penggunaan tanaman tradisional sebagai alternatif pengobatan pada zaman sekarang sangat dibutuhkan. Oleh karena itu akan diadakan sosialisasi dan demonstrasi mengenai pemanfaatan serta cara pengolahan tanaman tradisional sebagai alternatif pengobatan serta dapat juga digunakan sebagai peluang bisnis. Tanaman tersebut terdiri dari daun coklat, daun insulin, daun kelor, sereh wangi dan daun pandan. Metode yang digunakan yaitu sosialisasi dan demonstrasi pemanfaatan tanaman tradisional kepada masyarakat RT 21 dan RT 23 Desa Mekar Jaya. Hasil dari sosialisasi dan demonstrasi memiliki dampak yang besar terhadap masyarakat RT 21 dan RT 23 Desa Mekar Jaya, dilihat dari antusias masyarakat yang sangat baik ketika sosialisasi dan demonstrasi dilakukan. Dalam hal ini masyarakat dapat meningkatkan kreativitas dalam memanfaatkan tanaman sebagai alternatif pengobatan dan peluang bisnis.
Co-Authors 'Aliyah, Siti Hamidatul Achmad Noerkhaerin Putra Agung Pangestu, Tirto Agus Evendi Agusriani, Agusriani Ahmad Rozan Dewansyah Aisa Dinda Mitra AMANDA, REGINA Andriani, Medi Anggraini, Gusnia Anggresani, Lia Aprilia, Laurenc Ara Ofiana Arfiah, Besek armini hadriyati, armini Asnadewi, Veni Atika Kurniawati Atmaja, Anggito Surya Barmi Hartesi Biodola, Anggun Brata, Andy Brilian Nanda, Regita Debora Dwi Hardiyanti Deni Sutrisno Desi Sagita Dewansyah, Ahmad Rozan Dinda Melvia Eryunita, Putri Fahreza4, Zami Feranika Manik Fitri, Nadia Fitria Fitria Fresha Nurmayora Hafizah, Nurhafni Haflin Harrizul Rivai Hasanah, Rifdatul Hayatul Rahmi Hayatul Rahmi Helmi Arifin Hevira, Linda Indra Gunawan Jheni Ramayanti Utami Kartika Mustofa Kholilawati, Nelly Kiki Reski Ulandri Krisyanella Krisyanella Lara Syahila Latifah, Putri Ningrum Nurin Lesra Indriani Lia Anggresani Lili Andriani Lili Andriani Lili Andriani Linda Hevira M. Henityo Agung As'adi Melvia, Dinda Mitra, Aisa Dinda Monica, Bunga Munti, Putri Delina Cupa Nadia Monika Nike Nur Ahdiyah Novira, Tita Aulya Nurfazila, Nurfazila Nurhidayanti, Rts. Reni Nurinayah Nurinayah Nurinayah, Nurinayah Olin Santia Manora Oliyen Madori Pangaribuan, Ribka Permata, Intan Pitriani Purwantiningsih, Purwantiningsih Putri Agustina, Nadiva Putri Mariska, Ruri Putri Ningrum Nurin Latifah Rahma Anggun Suciati Rahmadevi Rahmadina, Rahmadina Raihana Salsabila Ramayanti Utami, Jheni Regina Amanda Regita Brilian Nanda Regita Brilian Nanda Retno Agustia Ningsih Ridha, M Sa'id Rohadi Ramlan Rosyta, Dini Galoh Ruri Putri Mariska Ruri Putri Mariska Santi Perawati Santi Perawati Santi Perawati, Santi Perawati, Santi Sanuddin, Mukhlis Sari, Wanti Puspita Sella Julia Ananda Shafira Al Fadhilah Siti Hamidatul 'Aliyah Suci Ramadani Suciati, Rahma Anggun Suhatri Suhatri Suntri, Suntri Supriadi Supriadi Supriadi Supriadi Suryani Suryani Sutrisno , Deny Tahta Kirana, Sahla Tirto Agung Pangestu Tita Aulya Novira Wely Yantari Yantari, Wely Yollanda N urulita Yulianis Yulianis Yuliawati Yuliawati Yuliawati Yuni Andriani ‘Aliyah, Siti Hamidatul