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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Biomolecular and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indian Journal of Forensic Medicine & Toxicology Jurnal Rekonstruksi dan Estetik Asian Journal of Health Research Bali Dermatology Venereology and Aesthetic Journal Folia Medica Indonesiana
Dwi Murtiastutik
Associate Professor Department Of Dermatology And Venereology Faculty Of Medicine, Universitas Airlangga/ Dr Soetomo General Academic Hospital;
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Journal : Biomolecular and Health Science Journal

 1 
Distribution Genotype High Risk (HR) And Low Risk (LR) Human Papillomavirus (HPV) at Condyloma Acuminata Gondo Mastutik; Alphania Rahniayu; Dwi Murtiastutik; Afria Arista; Trisniartami Setyaningrum; Nabiha Missaoui; Suhartono Taat Putra
Biomolecular and Health Science Journal Vol. 4 No. 1 (2021): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v4i1.26250

Abstract

Introduction: Condyloma acuminata that is also known as genital warts are one of the most common sexually transmitted that caused by infection of Human papillomavirus (HPV). Persistent infection of Low Risk (LR) or High risk (HR) HPV is a risk factor for progress into benign or malignant cancer. The objective is to analyze distribution of genotype LR-HPV and HR-HPV at condyloma acuminata in anogenital region. Methods: A cross sectional study using were 36 lesions from men and women of condyloma acuminata patients. All subject signed the informed consent and ethic obtained from our institution, number 382/Panke.KKE/V/2016. The specimen was used to histopathological examination and to identified 40 genotypes of HPV using a reverse line blot assay.Results: The All patients were diagnosed as condyloma acuminata, some with focus dysplasia and koilocytosis. All patients were positive for HPV, including LR-HPV were HPV 6, 11, 42, 54, 61, 81,87,89 and HR-HPV were HPV 18, 26, 45, 51, 52, 66, 67, 68B, 69, 82. The single infection of LR-HPV was 44.4%, multiple infection LR/LR-HPV was 13,9% and the multiple infection of LR/HR-HPV was 41.7%. The LR-HPV infected 70,6% and HR-HPV infected 29,4%.  Conclusion: LR-HPV is the major infection of condyloma acuminata, in single infection or multiple infection with HR-HPV. The most common infections were HPV 11, followed by HPV 6, HPV 18, HPV 51, and HPV 82. The determination of genotype of HPV can be used to predict the malignant transformation.
Co-Authors Afif Nurul Hidayati Afif Nurul Hidayati, Afif Nurul Afria Arista Afria Arista Afria Arista Afria Arista, Afria Agatha Anindhita Ardhaninggar Agatha Anindhita Ayu Ardhaninggar Agustina Tri Pujiastuti Alpha Fardah Athiyyah Alphania Rahniayu Alvian Arifin Saiboo Amanda Gracia Manuputty Amira Suryani Rahmatika Anggaraeni, Sylvia Ardsari Azminingrum Arifin Saiboo, Alvian Astindari Astindari Astindari Astindari Astindari, Astindari Bagus Haryo Kusumaputra Bernadya Yogatri Anjuwita Bernadya Yogatri Anjuwita Saputri Bintanjoyo, Lunardi Brama Rachmantyo Budi Utomo Budi Utomo BUDI UTOMO Budiono Budiono Budiono Budiono Chesia Christiani Liuwan Christina Avanti Cita Rosita Sigit Prakoeswa Cut Shelma Maharani Damayanti Damayanti Damayanti Damayanti Damayanti Desiana Widityaning Sari Devi, Aprilin Krista Dhelya Widasmara Diah Mira Indaramaya Diah Mira Indramaya Diana Kartika Sari Diana Kartika Sari, Diana Kartika Dyatiara Devy Rahadiyanti Emma Hidayati Sasmito Endang Wahyu Fitriani Erwin Astha Triyono Esti Hendradi Eva Lydiawati Evy Ervianti Fadila, Arisia Fajrin, Farah Meriana Farhat Surya Ningrat Febrina Dewi Pratiwi Gondo Mastutik Hari Sukanto, Hari Hariani, Lynda Harningtyas, Citra Dwi Hasnikmah Mappamasing Huvi, Indira Indah Purnamasari Indah Purnamasari INDROPO AGUSNI Ingrid Suryanti Suryono Intan Primasari Irmadita Citrashanty Irmadita Citrashanty Irmadita Citrashanty, Irmadita Irmalia, Shafira Isamahendra, Naufal Agus Iskandar Zulkarnain Iswinarno Doso Saputro Izzatul Fithriyah Jusuf Barakbah, Jusuf Kurniati Kurniati KUSUMASTUTI, ETTY HARY Laissa Bonita Lia Kinasih Ayuningati Linda Astari, Linda Lita Setyowatie Luthfidyaningrum, Hamidah M. Yulianto Listiawan Marsoedi Hoetomo Martodiharjo, Sunarko Maya Wardiana Maylita Sari Maylita Sari Maylita Sari, Maylita Medhi Denisa Alinda, Medhi Denisa Menul Ayu Umborowati Muhammad Vitanata Arfijanto, Muhammad Vitanata Nabiha Missaoui Nurul Hidayati, Afif Pepy Dwi Endraswari, Pepy Dwi Perdanakusuma, David Sontani Permana, Putu Bagus Dharma Pilar, Nissa Avina Prameshvari, Putu Lovina Indra Priangga Adi Wiratama Putri Halla Shavira Rahmadewi Rahmadewi Rahmadewi Regitta Indira Agusni Ridha Ramadina Widiatma Riswanto, Cintya Dipta Riyana Noor Oktaviyanti Sawitri Sawitri Sawitri Sawitri Sawitri Sawitri SEPTIANA SEPTIANA Septiana Widyantari Septiana Widyantari Sjahjenny Mustokoweni, Sjahjenny Sudjarwo Sudjarwo Suhartono Taat Putra Sunarso Suyoso Sunarso Suyoso, Sunarso Suryanegara, Jose Tanojo, Natalia Tengku Riza Zarzani N Tessa Thendria Tjokorde Istri Nindya Vaniary Trisiswati Indranarum Trisniartami Setyaningrum Umi Miranti Umi Miranti, Umi Wahyunita Desi Ratnaningtyas Wardiana, Maya Widyantari, Septiana Willy Sandhika Yuli Wahyu Rahmawati Yusuf Wibisono