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Optimasi Ekstraksi Sisik Naga (Drymoglossum Piloselloides) Tumbuhan Epifit Gambut Kalimantan Menggunakan Central Composite Design untuk Aktivitas Antioksidan. Arsana, Muafa Purwa; Monita, Dita; Rahman, Sudarman; Riana, Shesanti Citra; Febrianto, Yahya; Suprayogi, Thatit; Alfanaar, Rokiy; Fatiqin, Awalul
Jurnal Farmasi & Sains Indonesia Vol 7 No 1 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no1p112-117

Abstract

Dragon scale (Drymoglossum piloselloides) leaf is a plant that contains secondary metabolites with antioxidant potential. This plant is known for its easy to grow nature and has a wide habitat distribution. The extraction method using acetone solvent has been proven effective in extracting secondary metabolites from this plant. To improve the extraction efficiency, this study used an optimization approach using the Central Composite Design (CCD) method. CCD involves three main factors in extraction experiments, namely solvent concentration, extraction time, and extraction temperature. Experiments were conducted with variations of these factors to find the optimal extraction conditions. The results of CCD method showed that the solvent concentration of 70%, extraction temperature at 52°C, and extraction time of 60 minutes. Statistical analysis showed that the model used was significant, with an F-value of 9.20 and a P-value less than 0.01159, indicating that the factors tested had a significant effect on the extraction results. The results of this study have great potential in maximizing the use of dragon scale leaves as a source of antioxidant secondary metabolites.
Pengaruh Pertumbuhan Pakcoy (Brassica rapa l.) dengan Sistem Tanam Hidroponik Tipe Nutrient Film Technique (NFT) dan Media Kotoran Hewan (KOHE) Elon Jipasca; Muhammad Rifqi Shodri; Ansori Rahman; Putri Wineni; Awalul Fatiqin; Thathit Suprayogi; Yahya Febrianto; Sudarman Rahman; Muafa Purwa Arsana; Rokiy Alfanaar
Jurnal Biosilampari : Jurnal Biologi Vol 7 No 1 (2024): Biosilampari: Jurnal Biologi
Publisher : Universitas PGRI Silampari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62112/biosilampari.v7i1.150

Abstract

This study aims to assess the effect of planting media on pakchoi (Brassica rapa L.) growth. The research was conducted at Pak Slamet's Cipta Rasa Fruit Farm in October 2024. Each treatment used different planting media, with hydroponics supplemented with AB mix nutrients and KOHE without additional nutrients. The results showed that variations in growing media and nutrient supplementation had a significant impact on plant growth. The NFT hydroponic system gave the best results, with pakcoy reaching an average plant height (6.5 cm), number of leaves (8 leaves), and leaf width (5.8 cm) at 3-4 weeks after transplanting (HST) The results of plant height, number, and width of leaves from KOHE are listed. The provision of nutrients shows that the right amount and concentration can increase the overall growth of pakcoy.
Formulation and Evaluation of Physical Properties of Antioxidant Effervescent Granules and Extract of Karamunting Flower (Melastoma malabathricum L.) Shesanthi Citrariana; Yahya Febrianto; Thathit Suprayogi; Emma Ayudia Noriadita
INOVASIA Vol 2 No 2 (2024): April
Publisher : LPPM Institut Studi Islam Sunan Doe

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58330/inovasia.v2i2.359

Abstract

Karamunting (Melastoma malabathricum L.) contains several compounds with pharmacological activities including antioxidant, analgesic, anti-inflammatory, antipyretic and diuretic. Karamunting flowers contain flavonoid compounds, saponins and tannins. Tannin compounds can stabilize free radicals by complementing the electron deficiency of free radicals. To increase the utilization of karamunting flowers, it is formulated in the form of effervescent granules. This study aims to determine the ethanol extract of karamunting flower (Melastoma malabathricum L.) with concentrations of 1%, 2%, and 3% can be formulated in the form of effervescent granules. The physical properties of the granules were tested which included organoleptic test, flow rate test, granule compressibility test, dissolving time test and pH of effervescent granules. The results showed that formula 3 with a concentration ratio of 3% ethanol extract was a formula that met the requirements for the physical properties of the granules, namely with a sweet and sour taste, a characteristic odor of karamunting, and a dark purple-brown color. With an average flow rate of 2.853 g/sec, average compressibility of 21.12%, an average dissolving time of 7.52 seconds and a pH measurement of 5.
Improving the Quality of Students of SD Negeri 2 Rantau Pulut Lifestyle Characterized by Clean Water and Renewable Energy: Peningkatan Kualitas Gaya Hidup Siswa SD Negeri 2 Rantau Pulut Bercirikan Air Bersih dan Energi Terbarukan Fatiqin, Awalul; Alfanaar, Rokiy; Rahman, Sudarman; Febrianto, Yahya; Riana, Shesanti Citra; Karyadi, Karyadi; Sahari, Yudhi Ekakristian; Gunawan, Yohanes Edy; Arsana, Mu'afa Purwa; Suprayogi, Thathit
NAWASENA : JOURNAL OF COMMUNITY SERVICE Vol. 1 No. 02 (2023): Vol. 01 No.02 2023
Publisher : NAWASENA : JOURNAL OF COMMUNITY SERVICE

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Clean water is a vital requirement for children at the primary school level as it supports their learning process. The availability of clean water not only facilitates learning activities but is also an important aspect in supporting a lifestyle that is responsible for natural resources, especially in the context of using renewable energy. The emphasis on an appropriate lifestyle in the utilisation of clean water became the focus of the community service conducted at SD Negeri 2 Rantau Pulut. Through this socialisation activity, students were given an understanding of the importance of a clean lifestyle that utilises clean water sources wisely, while integrating the use of renewable energy. The results of this service showed positive progress. Students' understanding of the importance of a clean lifestyle and the utilisation of clean water with renewable energy has increased significantly, reaching an understanding level of 91.67%. From this, it can be concluded that this socialisation successfully achieved its goal of raising students' awareness of the importance of clean water and a sustainable lifestyle.
Kajian aktivitas antioksidan dan sitotoksik ekstrak etil asetat daun jarak pagar (Jatropha curcas) Rahman, Sudarman; Febrianto, Yahya; Citrariana, Shesanthi; Sulistia, Tiya; Alfanaar, Rokiy; Suprayogi, Thathit; Arsana, Mu’afa Purwa; Fatiqin, Awalul
Sasambo Journal of Pharmacy Vol. 6 No. 1 (2025): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v6i1.409

Abstract

Antioxidants are chemical substances that have the ability to protect body cells from damage caused by excessive oxidation reactions. One of the uses of antioxidants from natural materials is jarak pagar leaves (J. curcas). This study aims to determine the antioxidant and cytotoxic activity against shrimp larvae from ethyl acetate extract of J. curcas leaves. Ethyl acetate extract from J. curcas leaves was extracted using the soxhletation method. Phytochemical testing was carried out using the tube method, antioxidant testing using the DPPH method and cytotoxic using the BSLT method. The results of the research showed that J. curcas contained secondary metabolite compounds in the form of flavonoids and polyphenols, the antioxidant activity test of Ethyl acetate extract from J. curcas leaves and the comparison control (vitamin C) produced an IC50 of 71,79±0.35 ppm and 8.78±0.21 ppm, respectively. The cytotoxic test of the ethyl acetate extract of J. curcas leaves contains active compounds that are toxic to the shrimp larvae with an LC50 of 72.13 ppm (LC50≤1000 ppm). The most effective concentration in free radicals scavenging is 160 ppm. Based on the results obtained, the ethyl acetate extract of J. curcas showed strong antioxidant activity and potential as an anticancer agent.
Optimasi Tablet Levofloksasin Immediate Release Menggunakan Disintegran Sodium Starch Glycolate (SSG) dan Pengisi Laktosa dengan Metode Simplex Lattice Design (SLD) Shesanthi Citrariana; Akhmad Kharis Nugroho; Yahya Febrianto; Defilia Anograh Riani
JURNAL ILMIAH FARMASI SIMPLISIA Vol. 3 No. 2 (2023): Desember 2023
Publisher : Jurusan Farmasi, Politeknik Kesehatan Kementerian Kesehatan Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/jifs.v3i2.459

Abstract

Levofloksasin adalah antibiotik yang digunakan dalam terapi utama infeksi paru, juga merupakan sediaan farmasi yang memiliki penerimaan yang baik oleh pasien. Tablet immediate release memerlukan super disintegran yang merupakan eksipien dalam formulasi, perbedaan eksipien yang digunakan dapat memengaruhi bioperformance dari tablet. Optimasi formula digunakan sebagai metode untuk menentukan komposisi eksipien dalam formula. Penelitian ini bertujuan untuk melakukan optimasi formula tablet levofloksasin dengan metode simplex lattice design menggunakan sodium starch glycolate sebagai superdisintegran. Pembuatan tablet dilakukan dengan proses granulasi basah dan dikempa kemudian dilakukan pengujian sifat fisik berupa kekerasan, kerapuhan, waktu hancur dan disolusi efisiensi pada waktu ke 60 menit. Optimasi nilai prediksi dilakukan dengan cara observasi dan dibandingkan nilai responnya menggunakan one sample t-test. Hasil penelitian menunjukan bahwa perbedaan nilai SSG terlihat signifikan pada waktu hancur dengan nilai p<0,05 (0,0056). Hasil formula optimal dengan nilai desirability 0,811 berada pada komposisi SSG sebanyak 8mg/tablet. Pengujian konfirmasi memberikan hasil bahwa antara nilai prediksi vs observasi memberikan nilai yang tidak berbeda p>0,05. Dapat disimpulkan bahwa tablet levofloksasin yang diformulasikan memberikan nilai yang memnuhi kriteria baik sifat fisik dan efisiensi disolusi.
WORKSHOP METODE PENELITIAN TUGAS AKHIR MAHASISWA BIDANG TEKNOLOGI FARMASI DI MASA PANDEMI COVID 19 UNTUK MENGHASILKAN KUALITAS PENELITIAN YANG BAIK Pitarisa, Agustina Putri; Febrianto, Yahya; Dida, Nurista; Setiyaningsih, Wahyu
Devote: Jurnal Pengabdian Masyarakat Global Vol. 1 No. 2 (2022): Devote : Jurnal Pengabdian Masyarakat Global, Desember 2022
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (418.933 KB) | DOI: 10.55681/devote.v1i2.364

Abstract

The spread of Covid-19 has had many impacts in various sectors, one of which is the education sector. Currently, many activities in educational institutions are limited or even stopped. SStudents’final research is also affected since students’ target and desire to obtain maximum results were hindered by Covid-19 which limited them to using laboratories and libraries. The objective of this research is to help students complete their final assignments effectively and to improve the quality of their final project research during the pandemic. It employed the lecture and Q&A methods. Evaluation was carried out by conducting needs analysis and then reporting the results of the data analysis. The results obtained include: 1) final year students already have knowledge related to the equalization of perception of scientific paper and technique of writing scientific paper in pharmaceutical technology, 2) students know the target of completing the cientific paper.
Sosialisasi Peraturan Pemerintah tentang Perlindungan Tumbuhan Dan Satwa Liar untuk Mendukung Pengelolaan Hutan Desa Tuwung Fatiqin, Awalul; Kadafi, Ahmad Muammar; Febrianto, Yahya; Kamison
Jurnal SOLMA Vol. 13 No. 1 (2024)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v13i1.12867

Abstract

Background: The highly biodiverse Tuwung Village Forest has been the site of a productive collaboration between the village community and the government in an effort to manage a sustainable environment. The unique and rare flora and fauna in this forest have benefited significantly from this collaboration. Populations of rare species have increased, and disturbed ecosystems have also experienced significant recovery. The main objective of this collaboration is to maintain the sustainability of the environment and natural resources in Tuwung Village in line with applicable regulations, especially the Minister of Environment and Forestry Regulation No. 106. Method: Assistance using the Asset Based Community Development (ABCD) method has been adopted in the implementation of PLHD management socialization in Tuwung Village. Result: The results of the analysis show that the participants, namely the managers of KPHD Tuwung, have achieved a very good level of understanding regarding various key aspects, such as the role and function of the area protection and security section (95%), area patrol scheme (98%), animal protection status (100%), data collection and reporting (90%), and animal release (100%). Conclusion: The high level of enthusiasm from the participants reflects their commitment to implementing PLHD management concepts, which are expected to contribute significantly to sustainable environmental conservation in Tuwung Village.
Inovasi Pengembangan Teknologi Sistem Otomatis Pengendalian Hama di Kebun Buah Kelompok Tani Harapan Kota Palangka Raya Arsana, Mu afa; Ngazizah, Febri Nur; Wilda, Robiatul Witari; Adi, Mika; Jipasca, Elon; Febrianto, Yahya; Alfanaar, Rokiy; Rahman, Sudarman; Suprayogi, Thathit; Citrariana, Shesanthi; Fatiqin, Awalul
Al-Khidmah Jurnal Pengabdian Masyarakat Vol. 5 No. 3 (2025): SEPTEMBER-DESEMBER
Publisher : Institute for Research and Community Service (LPPM) of the Islamic University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56013/jak.v5i3.4923

Abstract

The Community Service Program was carried out at the Harapan Farmers Group, Kereng Bangkirai Sub-district, Palangka Raya City, as an effort to provide innovative solutions to pest attack problems that often reduced fruit farm productivity. Previously, farmers had relied on manual pesticide spraying, which required considerable time, labor, and cost, and posed health risks. To address this challenge, the service team from the University of Palangka Raya developed an automated pest control system that was able to regulate pesticide spraying independently and efficiently. The activities were conducted through stages of socialization, training, and system mapping of automation in the fruit farm area, involving members of the farmers group actively. The implementation results showed an increase in participants’ understanding of the technology by 30–40 percent, improved efficiency in pesticide use by up to one-third compared to manual methods, and a reduction in working time by nearly 50 percent. This activity not only improved farmers’ skills and productivity but also served as a concrete step toward the implementation of sustainable smart farming in Palangka Raya through collaboration between the university and the community.
Peningkatan Kapasitas Produksi Gummy Candy Sehat Berbasis Buah Lokal melalui Pelatihan dan Transfer Teknologi Citrariana, Shesanthi; Ayu, Regina Wahyudyah Sonata; Riani, Defilia; Desindria, Galang Rizdho; Yosaeunike, Vitatani; Febrianto, Yahya; Alfanaar, Rokiy; Rahman, Sudarman; Suprayogi, Thathit; Arsana, Mu afa; Fatiqin, Awalul
Al-Khidmah Jurnal Pengabdian Masyarakat Vol. 5 No. 3 (2025): SEPTEMBER-DESEMBER
Publisher : Institute for Research and Community Service (LPPM) of the Islamic University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56013/jak.v5i3.4924

Abstract

The problem of fruit waste due to oversupply in agritourism, which causes economic losses and environmental burdens, is the focus of this community service activity. The program aims to enhance partners' capacity through training and technology transfer in producing healthy gummy candy from local fruits. Implementation methods included observation, socialization, practical training, and evaluation involving 20 participants from Agrowisata Cipta Rasa Pak Slamet. The results showed significant improvement in three aspects: conceptual and material understanding (85-90%), procedural skills (95%), and partner enthusiasm and motivation (100%). The implementation of green economy principles was achieved through the conversion of fruit surplus into high-value products with extended shelf life. This program successfully established a strong production foundation while creating a sustainable green value chain. It is concluded that the participatory training approach effectively empowers partners and is ready to be replicated in other locations with similar problems. Program sustainability is ensured through partner commitment and an agreed-upon production monitoring plan.
Co-Authors Abdul Chakim Adi, Mika Agustina Putri Pitarisa Agustina Putri Pitarisa Sudarsono Ahmad Irawan Ahmad Muammar Kadafi Akhmad Kharis Nugroho Alfanaar, Rockiy Alfanaar, Rokiy Allaya Adistia P Ana Indrayati Anna Dwiningsih Ansori Rahman Arsana, Mu afa Ayu, Regina Wahyudyah Sonata Ayuningtyas, Nurista Dida Buanasari Buanasari, Buanasari Cholifah Citrariana, Shesanthi Citrariana, Shesanti Decenly Decenly Decenly, Decenly Defilia Anogra Riani Defilia Anograh R Defilia Anograh Riani Desindria, Galang Rizdho Desy Suweni Nugrahaningtyas Dewi, Apriana Dida, Nurista Dita Monita Elfahmi . Elon Jipasca Elsandi, Elsa Emma Ayudia Noriadita Erindyah Retno Wikantyasning Fatiqin, Awalul Fauzan Fikri Fauziah, Anisa Rahma Febri Nur Ngazizah Febri Nur Ngazizah Fifi Nur Apriliani Franz June N Gintoro, Atilla Dian Dewanti Gunawan, Yohanes E Gunawan, Yohanes Edy I Nyoman, Sudyana, Jipasca, Elon Kamison Karyadi Karyadi Karyadi Karyadi Kiki Septiyani Manik, Adelia Margareta Mariasa, Joice Cleriska Masithoh Nur Mega Eka Yuniyasanti Monita, Dita Mu&#039;afa Purwa Arsana Muhamad Taufik Hidayat Muhammad Priyadi Muhammad Rifqi Shodri Muhammad Sadam Rahmansyah Mu’afa Purwa Arsana Ngazizah, Febri Nur Norhusna, Norhusna Novia Putri Santari Nur Hidayat Nurista Dida Parametta, Vidya Pitarisa, Agustina Putri Prasetyo, Alno Pritaningtyas, Nazifa Wulan Puspa Dwi Pratiwi Putri Wineni Putri, Alayya Adistia Putri, Luluk Aniqoh Meliana Ra Hoetari Tirta Amelia Rahman, Sudarman Ratna Yuliana Riana, Shesanti Citra Riani, Defilia Riri Novita Sunarti Rizki Rachmad Saputra Sahari, Yudhi Ekakristian Samsul Arifin Sandi Mahesa Yudhantara Sawal, Rizky Ardian Hartanto Setiyaningsih, Wahyu Shavira Elphasa H Shesanthi Citrariana Shesanti Citra Riana Shesanti Citra Riana Shodri, Muhammad Rifqi Simajuntak, Ruth Riama Siti Sunariyati Sudarman Rahmman Sulistia, Tiya Syarifah Syarifah Thathit Suprayogi Wahyu Setiyaningsih Wahyu Setiyaningsih Wilda, Robiatul Witari Yithro Serang Yithro Serang Yithro Serang Yohanes Edi Gunawan Yosaeunike, Vitatani Yudhi Ekakristian Sahari Yulita, Elia