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Samitra, Dian
Department Of Biology Education, Universitas PGRI Silampari
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Journal : scripta biologica

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PENGARUH AIR REBUSAN DAUN MAMPELAS (Tetracera indica Merr.) TERHADAP KADAR KOLESTEROL DARAH MENCIT Dian Samitra; Zico Fakhrur Rozi
Scripta Biologica Vol 4, No 3 (2017)
Publisher : Fakultas Biologi | Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (485.298 KB) | DOI: 10.20884/1.sb.2017.4.3.453

Abstract

Tetracera indica Merr. locally known as Mampelas is commonly used in traditional remedies. It believed to have the potential to cure hypercholesterolemia. The potential use of this plant to lower blood cholesterol level was understudied; therefore this study aimed to determine the effect of the infusion of fresh leaves of Tetracera indica to the blood cholesterol levels of mice. This research was true experimental design, a post-test only design with nonequivalent (control) groups. This study used 25 male mice divided into five categories, i.e., P0 mice were administered with 0 g of infusion, P1 mice with 2 g infusion, P2 mice with 5 g infusion, P3 mice with 10 g infusion, and P4 mice without Tetracera indica infusion but 10 mg of simvastatin. The treatment in all categories were given continuously for seven days. The results showed the mean of the blood cholesterol levels were 169.4 ± 59.37 mg/dL in P0, 121.8 ± 7.62 mg/dL in P1, 136.2 ± 15.69 mg/dL in P2, 110.6 ± 37 , 01 mg/dL in P3 , and 179,0 ± 35,24 mg/dL in P4. Kruskal Wallis test was calculated to determine the difference of blood cholesterol level among all groups, and it reported p < 0.05. The results of this study showed that infusion of Tetracera indica leaf was significantly lowered the level of blood cholesterol in mice.
Co-Authors AA Sudharmawan, AA Amelia, Wilda Andri Valen Andri Valen Arisandi, Desy Armi Yuneti Armi Yuneti Arum Setiawan Arum Setiawan Aulia Citra Bayumi, Nasrul Delta Syahsabilla Deo Alfa Riski Destien Atmi Arisandy Dewi Liamawati Dwi Novita Eka Lokaria, Eka Endang Suswati Endang Widi Winarni Endang Widi Winarni Enjellica Dwi Ariyani Erma Oktarina Erpita, Rosi Eryani, Rita Febrian, Aldi Ayang FERI SETIAWAN Fitria Lestari Hadiwinarto Hadiwinarto Harmoko Harmoko Harmoko Harmoko Herawati, Emi Hessy Adellya Sari Indra Yustian Intan Puspita, Intan Jimi Brandia Joko Wiryono Joko Wiyono Kusnanto, R Angga Bagus Lulu Wahyu Nita Sari M. Lutfi Firdaus Mahdi, Ibnu Mareta Widiya Mareta Widiya, Mareta Maulise Enjellina Aprilia Merti Triyanti Meti Yunita Miftahusalimah, Pingkan Luthfiyyah Muhammad Bagas Abisali Muhammad Kristiawan Nayra Naysila Naysila Imelda Nopa Nopiyanti Novita Malasari Nugroho Aji Nura Maziyyatul Izza Okta Malia Okta, Nellayuni Verdani Peli Marjihan Penti Fidiana Permadi, Adun Permata Sari, Dwi Alia Putri Octariani R Angga Bagus Kusnanto Rambat Nur Sasongko Reny Dwi Riastuti Reny Dwi Riastuti Reny Dwi Riastuty Riska Aulia Riska Rahmadhani Riya Amelia ROSMALINA, EEN Sanjaya S. Satinem Sela Sulistia Sepriyaningsih Sepriyaningsih Sepriyaningsih, Sepriyaningsih Septiana Septiana Septiana Sifa`u Rahmah Siswahyudianto Sonia Nopita Sari Sujarwo Sujarwo Tiara Yulisah Tio Gusti Satria Tria Octaviany Tuginah T Tuhim Setia Ulva Ulva, Tuhim Setia Vadilla Valensi Wardianti, Yunita Yuli Febrianti Yulita Olpy Insani YULIZAH, YENY Yuni Krisnawati Yuni Krisnawati Yupita Anjelica Dinissjah Zhafirah Aulia Zico Fakhrur Rozi