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All Journal PHARMACON Pharmaciana: Jurnal Kefarmasian Majalah Obat Tradisional MPI (Media Pharmaceutica Indonesiana) Jurnal Pengabdian Al-Ikhlas BERNAS: Jurnal Pengabdian Kepada Masyarakat Health Media JUKESHUM: Jurnal Pengabdian Masyarakat Jurnal EduHealth Journal Prima Health Science Jurnal Kesehatan dr. Soebandi Medical Sains : Jurnal Ilmiah Kefarmasian J-CEKI
Shinta Mayasari
Fakultas Ilmu Kesehatan Universitas Dr Soebandi, Jember, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Exploring the Potential of NIR Spectroscopy and Chemometrics to Verify the Flavonoid Content in Litsea cubeba Cendekiawan, Khrisna Agung; Susanti, Dhina Ayu; Isnawati, Nafisah; Mayasari, Shinta; Riswanto, Florentinus Dika Octa
Majalah Obat Tradisional Vol 30, No 2 (2025)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.99185

Abstract

The ancient records about herbal medicine show traditional healing practices are deeply rooted in Indonesian culture. The medical use of plants decreased because of inheritance customs combined with the lack of written documentation on medicinal plants but dependent on oral information transmission. Traditional research and preservation activities of local healing plants which belong to specific cultural communities become possible through this phenomenon. Researchers conducted ethnopharmacological research about antidiarrheal medicinal plant uses that included traditional knowledge about flavonoid-containing plants within the Osing ethnic group of West Java Indonesia. The goal of this research was to verify flavonoid compounds in Osing's medicinal plants through Near Infra-Red (NIR) spectroscopy combined with chemometric methods. The evaluation of antidiarrheal potential for these compounds relied on flavonoid standard reference substances because these compounds demonstrate strong antioxidant properties which stabilize intestinal functioning. Chemometric techniques together with Near Infra-Red spectroscopy (NIR) were applied to analyze krangean leaves (Litsea cubeba) in order to establish their flavonoid compound levels. The quality assessment of multivariate calibration models shows that PLS regression produces RMSEC of 2.870 and RMSEP of 0.0124 with R2cal = 0.9931 and R2val = 0.9919. The analysis using linear discriminant analysis (LDA) succeeded in its completion with recognition rates above 90% for each discriminating class.
Co-Authors Afnan Septi Mulyani Afnan Septy Mulyani Afrizal Maulidan Rachmawan Agustin, Ayu Tri Alfarisi, Hilmi Pratama Alfi Nur Ramadhani Alvia Putri Priyono, Rosyidatul Amalia Wardatul Firdaus Ambari, Yani Anas, Mohammad Nizar Anggitasari, Wima Anggraeni, Linda Suci Anggraeni, Lutvi Arista Wahyu Ningsih Atmanegara, Stivani Yanti Aulia, Andira Aura Denaneer Mulya Aura Denaneer Mulya Ayu Angger Putri M. Soleh Ayu Dwi Wardani Bekti Kusuma Primadani Damayanti, Mita Eka Damayanti, Selvi Danny Dwi F Danny Dwi Firmansyah Darrojah, Urfi Narva’u DEWI RAHMAWATI Dewi, Novi Rosita Dina Trianggaluh Fauziah Dinayah, Syafinatud Dinda Febri Puspitasari Dinda Febri Puspitasari Dwi Koko Pratoko Dyan Wigati Fadli Muhammad F Fadli Muhammad Fathoni Fadli Muhammad Fathony Fahrur Rozi Shodiqi Fendy Prasetyawan Fitria, Ayu Florentinus Dika Octa Riswanto Hasanah, Adinda Shofiatul Hasiseh Hasiseh Heri Setyo Budi Hidayati, Sholihatil Indah Suciati Iski Weni Pebriarti Ismanti, Septie Putri Kanaya Dewayanti Khrisna Agung C Khrisna Agung Cendekiawan lindawati setyaningrum Maheswari, Anindya Dinarya Martina, Ina Muhammad Alvin Yovansya Mu’affan, Achmad Adha Nabila, Talitha Vanian nafisah isnawati Nanda Pradwitha Fariansiska Novyananda Salmasfattah Pangesti, Yuli Pebriarti, Iski Weni Permatasari, Shafira Restu Pramesti, Lita Aulia Putra, Zulkarnain Permana Putri Ramadani Putri Ramadhani Putri, Masitah Nurwidiya Qurrotul Aini Rahmadania Affelia Dianto Ramadhan Bagus Cahyono Ramadhan, Muhammad Ridho Ratna Amelia Ratna Amelia Ressi, Monica Risqi Wahyudi rofiqoh rofiqoh savitri, Lisa Siti Aisyah Siti Hotima Siti Hotimah Siti Nur Maulita Soleh, Ayu angger Putri M. Stevi R izky Anandha Susanti, Dhina Ayu Swastika, Melur Tri Taniya Tri Oktavia Ningrum Tuhfatul Hilmits T Tuhfatul Hilmits Tsania Ulum, Miftahol Wanda Tri Agustin Wardani, Ali Ridho Wardhani, Firdha Aprillia Wima Anggitasari Yola Kristina Cendani Yuneka Saristiana Zulkarnain Permana