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All Journal PHARMACON Pharmaciana: Jurnal Kefarmasian Majalah Obat Tradisional MPI (Media Pharmaceutica Indonesiana) Jurnal Pengabdian Al-Ikhlas BERNAS: Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian Masyarakat Madani JUKESHUM: Jurnal Pengabdian Masyarakat Jurnal EduHealth Jurnal Farmasi Tinctura Jurnal Pengabdian Masyarakat Bidang Sains dan Teknologi Journal Prima Health Science Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Cendekia Ilmiah Sadewa: Jurnal Pengabdian Masyarakat Indonesian Pharmacopeia Journal (IPJ)
Shinta Mayasari
Program Studi Sarjana Farmasi, Fakultas Ilmu Kesehatan, Universitas Dr. Soebandi Jember
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Profil Pengobatan Pada Pasien Tuberkulosis Di Rumah Sakit Paru Jember Anggie Noviana Putri; SHINTA MAYASARI
Tinctura Vol 7 No 1 (2025): Jurnal Farmasi Tinctura
Publisher : Program Studi S1 Farmasi Fakultas Ilmu Kesehatan Universitas Ibrahimy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35316/tinctura.v7i1.8117

Abstract

Tuberkulosis (TB) identik dengan penyakit yang disebabkan Mycobacterium tuberculosis yang ditularkan melalui droplet udara. Tatalaksana TB dapat diberikan terapi dalam jangka waktu panjang dengan regimentasi yang diberikan sesuai standar. Populasi pasien TB pada periode terakhir 2024 adalah sejumlah 1.582 kunjungan pasien TB. Tujuan penelitian ini adalah untuk mengetahui gambaran tatalaksana pengobatan pada pasien TB di Rumah Sakit Paru Jember. Jenis penelitian ini adalah penelitian deskriptif secara kuantitatif dengan pengumpulan data secara retrospektif. Jumlah sampel sejumlah  94 responden TB dengan menggunakan random sampling. Analisis data berupa analisis univariat, data disajikan dalam bentuk frekuensi dan persentase. Hasil penelitian menunjukkan kategori jenis kelamin laki-laki sejumlah 64,89%, kategori usia 49–59 tahun sejumlah 38,30%. Penggunaan terbanyak yaitu 4 FDC (Fix Doses Combination) dengan dosis 150mg/ 75mg/ 400mg/ 275mg dan frekuensi dari penggunaan yaitu 1x3 sebesar 50%. Profil pengobatan TB di Rumah Sakit Paru Jember menunjukkan bahwa terapi obat TB yang digunakan sesuai dengan panduan formularium di Rumah Sakit Paru Jember.
Evaluasi Ketepatan Obat Antituberkulosis pada Pasien Tuberkulosis Paru di Rumah Sakit Paru Jember Alfira Rosaliana; SHINTA MAYASARI
Tinctura Vol 7 No 1 (2025): Jurnal Farmasi Tinctura
Publisher : Program Studi S1 Farmasi Fakultas Ilmu Kesehatan Universitas Ibrahimy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35316/tinctura.v7i1.8118

Abstract

Tuberculosis (TB) adalah penyakit yang disebabkan oleh Mycobacterium yang menyerang organ paru. Efektiitas pengobatan TB dapat diukur dengan menbandingkan pengobatan dengan pedoman acuan dari Rumah Sakit. Permasalahan ketidaktepatan obat dari penelitian sebelumnya adalah 5% dari total 82 pasien. Tujuan penelitian ini untuk memberikan evaluasi ketepatan obat pada pasien TB. Jenis penelitian ini adalah penelitian deskriptif secara kualitatif dengan menggunakan data rekam medis secara retrospektif. Jumlah sampel yang dibutuhkan adalah 95 sampel dengan menggunakan random sampling. Analisa data menggunakan analisis univariat dengan menampilkan data frekuensi dan persentase. Dari sejumlah 95 sampel terdapat, keseluruhan terapi obat yang diterima pasien adalah tepat. Sejumlah 92,63% menerima terapi dalam bentuk 4FDC, sedangkan 4,21% pasien meneriam 2FDC, dan sejumlah 3,16% pasien menerima sedian lepas yang diberikan secara terpisah.
Potential Hyperglycemia In Type 2 Diabetes Mellitus Patients Due To Drug Interactions At Hospital Avrillana Dewangi Gea Ayunda Diarso; Shinta Mayasari; Khrisna Agung Cendekiawan
Indonesian Pharmacopeia Journal Vol. 1 No. 2 (2024): July
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/ipj.v1i2.19

Abstract

Background: Hyperglycemia is a medical condition in the form of an increase in blood glucose levels beyond normal limits with a blood sugar concentration of ≥200 mg/dl. Hyperglycemia that is not well controlled can cause serious disorders of the body's systems, especially the nerves and blood vessels. Based on WHO data, the prevalence of type 2 DM with the potential for hyperglycemia in the world in 2019 was 5.3%. This figure is expected to increase to 6.3% in 2030. Objective: This research was conducted to determine the potential for hyperglycemia in type 2 diabetes mellitus patients due to drug interactions at one of hospital in Jember. Method: This research uses a quantitative design with retrospective data collection, namely research obtained based on information from patient medical records. The population in this study was 539 patients suffering from type 2 diabetes mellitus for the period January-December 2022. The sample from this study was type 2 diabetes mellitus patients who met the inclusion criteria. Sampling was calculated using the Slovin formula using random sampling techniques and the results obtained were 84 medical record samples. Analysis using univariate. Data is displayed in frequency and percentage form. Data processing uses Microsoft Excel and SPSS. Results: Most of the drugs received by type 2 diabetes mellitus patients experienced interactions that had the potential to cause hyperglycemia with blood sugar levels ≥200 mg/dl (96.43%) and a moderate clinical significance level of 70.24%. Conclusion: There is a potential for hyperglycemia caused by diabetes drug interactions. Monitoring drug interactions and effective treatment in patients with type 2 diabetes mellitus needs to be carried out to achieve optimal therapy targets and increase awareness of healthy lifestyles in diabetes management.
Potential Hypoglycemia in Patients With Type 2 Diabetes Mellitus Due to Drug Interactions in Citra Husada Hospital Elisa wardatul awaliya; shinta mayasari; khrisna agung cendekiawan
Indonesian Pharmacopeia Journal Vol. 1 No. 2 (2024): July
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/ipj.v1i2.24

Abstract

Diabetes mellitus (DM) is a metabolic disorder disease characterized by an increase in blood glucose due to decreased insulin secretion by pancreatic beta cells, insulin disorders or resistance. The main risks that are commonly found in every patient diagnosed with DM disease include hypoglycemia. In a study conducted at a public hospital in Jakarta, 186 incidents of interaction of antidiabetic drugs with other drugs that have hypoglycemia potential with a moderate clinical significance level of 83.8% were found. The potential for drug interactions in DM patients is still very frequent. This can be caused by the number of drugs that are often used (Polipharmacy or multiple drug therapy). The purpose of this study is to identify the potential for hypoglycemia in type 2 DM patients due to drug interactions at Citra Husada Jember hospital. This type of research is qualitative research with retrospective data collection. The design of this study uses a cross-sectional design. The population of this study is 662 medical record data of outpatients with type 2 diabetes for the period of January – December 2022. Data analysis uses univariate analysis. In this study, most patients have the potential to experience hypoglycemia.
DESCRIPTION OF CLINICAL POLYPHARMACY PRESCRIPTIONS IN TYPE 2 DIABETES MELLITUS PATIENTS AT HOSPITAL X JEMBER DISTRICT Nurul Fathona; Shinta Mayasari; Nafisah Isnawati
Indonesian Pharmacopeia Journal Vol. 1 No. 2 (2024): July
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/ipj.v1i2.29

Abstract

Background: Diabetes mellitus (DM) is a metabolic disease caused by insulin resistance and pancreatic beta cell dysfunction. Polypharmacy is the use of three or more drugs every day is very common in patients with diabetes mellitus. WHO data shows that the prevalence of Diabetes Mellitus (DM) polypharmacy will reach 7.4% - 43.4% by 2023. Objective: This study aims to determine the clinical picture of polypharmacy prescriptions in patients with type 2 diabetes mellitus at X Hospital, Jember Regency. Method: This study used a descriptive non-experimental method by observation, involving 80 samples. Samples were selected by random sampling and data were analysed and displayed in the form of frequencies and percentages using Microsoft Excel and SPSS. Results: The results of this study are the description of the most polypharmacy prescriptions, namely prescriptions with 3 drug items as many as 3 prescriptions (7.5%), and the description of the least polypharmacy prescriptions, namely prescriptions with 4 drug items, and prescriptions with 10 drug items as many as 1 prescription (1%). In addition, the results of this study also contained drug interactions as many as 72 interacting prescriptions. Conclusion: From the discussion above, it can be concluded that, in the study at Hospital X, Jember Regency, polypharmacy was found from the samples analysed, all of which were polypharmacy prescriptions. This study also found that prescriptions for type 2 diabetes mellitus patients experienced drug interactions with moderate interactions being the most common. These interactions can reduce the effectiveness of treatment and increase risks for patients.
ADMINISTRATIVE AND PHARMACEUTICAL SCREENING OF DIABETES MELLITUS PRESCRIPTIONS IN TYPE 2 DIABETES MELLITUS PATIENTS IN THE HOSPITAL X JEMBER. Michael Nicoin DC Michael Nicoin DC; Shinta Mayasari
Indonesian Pharmacopeia Journal Vol. 2 No. 1 (2025): January 2025
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/ipj.v2i1.32

Abstract

AbstractBackground: Pharmaceutical services are drug and clinical pharmacy services that enhance therapeutic effects and minimize the risk of medication errors. A form of pharmaceutical service is prescription screening. Prescription screening is a prescription review which is an activity of pharmacists in reviewing prescriptions which includes administration before the prescription is compounded. Another study conducted by Aryzki entitled "Administrative completeness of prescriptions carried out at Pharmacy X Banjarmasin in January, completeness of 0.26%, incompleteness with a percentage of 99.74% has not met according to PERMENKES number 73 of 2016 concerning pharmaceutical service standards. Objective: To identify the administrative and pharmaceutical screening of DM prescriptions for type 2 DM patients at X Jember Hospital. Methods: Descriptive research using observation method with a total of 125 samples by Random Sampling using the slovin formula. Results: overall administrative completeness is 100% complete written indicators, while most of the pharmaceutical completeness (60%) is incomplete of the five indicators identified as not written, namely the dosage form is still 56.8%, the dosage of the drug is still 91.2%, and overall 100%, the rules of use have not been written. Conclusion: From the total sample taken 125 prescriptions in the administrative aspect were all written completely for the pharmaceutical aspect most of them were not written completely, namely the indicators of drug dosage forms, drug dosages, and rules of use. Keyword : Skrining; Administrative; Phasmaceutical; Indicato
Effectiveness of Ethanol Extract of Mangosteen Leaves (Garcinia mangostana L.) as Anti-diarrhea in Mice Induced by Oleum Ricini Ahmad Khoirul Azwar; Shinta Mayasari; Mohammad Rofiq Usman
Indonesian Pharmacopeia Journal Vol. 2 No. 1 (2025): January 2025
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/ipj.v2i1.34

Abstract

Diarrhea is a condition where a person experiences defecation with a soft or liquid consistency, with more frequent frequency (generally three or more times) a day One of the plants used as treatment for diarrhea is mangosteen leaves (Garcinia mangostana L). The leaves of the mangosteen plant (Garcinia mangostan L.) contain tannin compounds which can be useful as an antidiarrheal. Tannin is a substance that is effective as an adstringents, so it is thought to be able to provide an anti-dare effect. To determine the effectiveness of ethanol extract of mangosteen leaves (Garcinia mangostana L) as antidiarrhea in male white mice (Mus musculus) induced by oleum ricini. This research uses a type of laboratory experimental study using male mice (Muss musculus L) that have been induced with oIeum ricini. There were 15 mice used and divided into 5 groups, namely: negative control group (CMC Na 0.5%), positive control group (loperamide HCl) and treatment groups with dose concentrations of 250 mg/kgBW, 450 mg/kgBW and 650 mg/ kg BW. The research results showed that mangosteen leaves contain flavonoids and tannin compounds. This study shows the antidiarrheal activity value of 3 extract dose groups. There were 4 test parameters with the greatest antidiarrheal activity results at a dose of 650 mg/kgBB. The average result of the onset of diarrhea was 62.3 minutes, then the average result of the frequency of diarrhea was 5 times, while the duration of diarrhea was 85 minutes with an average feces weight of 0.99 grams. The ethanol extract of mangosteen leaves at a dose of 650 mg/kgBW had the most effective antidiarrheal activity in male (mus musculus) mice induced by oleum ricini. Key words: anti-diarrhoea, mangosteen leaves, loperamide; oleum ricini, garcinia mangostana
Identification of Transcribing Errors in Prescriptions for Type 2 Diabetes Mellitus Patients at Clinic X, Jember Haris Agung; Shinta Mayasari; Fendy Prasetyawan
Indonesian Pharmacopeia Journal Vol. 2 No. 1 (2025): January 2025
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/ipj.v2i1.39

Abstract

Abstract Background: Clinical Pharmacy Services play an important role in health services in hospitals. Pharmaceutical service standards are direct and responsible services to patients related to pharmaceutical preparations with the aim of achieving definite results to improve the quality of life of patients. Medication error (ME) is an incident that causes or has an impact on inappropriate drug services or endangers patients when the drug is under the control of health workers or patients. Transcribing Error (TE) is an error in reading a prescription before entering the dispensing stage. TE includes changes to the drug name, drug formulation, route, dose, dosage regimen to prescription orders. According to the East Java Health Service in 2021, Diabetes Mellitus (DM) sufferers in East Java were 2.6 of the population aged 15 years and over. Health services for diabetes mellitus sufferers at first-level health facilities (FKTP) in 38 districts/cities throughout East Java reached 867,257 cases (93.3% of the estimated DM sufferers. Based on dataBasic Health Research, 2021cases of diabetes mellitus in Jember amounted to 1.4%. This study aims toIdentifying transcription errors in prescriptions for type 2 DM patients at clinic x, Jember district. This research uses research descriptive using observation method The data source taken from this study is data from outpatient prescriptions for type 2 Diabetes Mellitus for the period January - December 2022-2024 at clinic x Jember district. The population of this study was 37 medical prescriptions for outpatients with type 2 DM for the period January - December 2022-2024 at clinic x Jember. The sample in this study was prescription data for patients diagnosed with type 2 DM who met the inclusion and exclusion criteria with a total of 37 samples by total sampling. The results of this study were obtained. Data from the identification of transcription errors still contained errors. From the total sample taken, 37 prescriptions, the results of the identification of transcription errors still contained errors including no medical record number (89.2%) no patient age (45.9%) no dosage form (43.2%). While the parameters of patient name, drug name, dosage, duration of administration, route of administration, date of prescription request have been complete, there are no errors.From the discussion above, it can be concluded that the results of transcription error identification still contain errors. Keywords:Medication error, transcribing error, DM type 2
The PROFILE OF ANTIBIOTIC USE IN PATIENTS WITH URINARY TRACT INFECTIONS AT ABDOER RAHEM GENERAL HOSPITAL, SITUBONDO Hafiz Achmad Hafiz Auni Iswanto; SHINTA MAYASARI; Sholihatil Hidayati; Nur Hasanah
Indonesian Pharmacopeia Journal Vol. 2 No. 2 (2025): 31 July 2025
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/ipj.v2i2.50

Abstract

Harmful bacteria multiply, causing urinary tract infections (UTIs). Patients with urinary tract infections often receive antibiotics and supportive care. This study aims to assess the pharmacological treatment of patients with urinary tract infections at RSUD Abdoer Rahem Situbondo. This study used a descriptive design by collecting data retrospectively. This study used a sample of thirty medical records taken using total sampling from May to August 2024. The findings are presented in the form of tables and percentages. The results showed that RSUD Abdoer Rahem Situbondo used urinary tract infection drugs, with 90% of the pharmaceuticals included in the antibiotic class, and cefixime was the most commonly used antibiotic at 27.27%. Ondansetron was the dominant additional treatment, accounting for 21.5% of the total use of additional drugs, followed by ranitidine and lansoprazole at 16.07% and omeprazole and ketorolac at 14.29%.
Literature Review: Pharmacological Activity and Characteristics of Red Onion (Allium cepa L.) Arista Wahyuningsih; Shinta Mayasari; Iski Weni Pebriarti; Sepbrilla Ananda Kusriadi
Indonesian Pharmacopeia Journal Vol. 2 No. 2 (2025): 31 July 2025
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/ipj.v2i2.54

Abstract

Shallot skin (Allium cepa L.) is a household waste that is still rarely utilized, even though it contains secondary metabolites such as flavonoids, anthocyanins, saponins, tannins, and other phenolic compounds that have pharmacological potential, especially as antioxidants and antibacterials. This study evaluates shallot skin's specific and non-specific pharmacognosy parameters through literature studies. Specific parameters include organoleptic, microscopic tests, and identifying active compound content using TLC, while non-specific parameters include water, ash, and contamination. The literature search method was done through Google Scholar, PubMed, and ScienceDirect, using the criteria of articles from 2015 to 2025. The study results indicate that flavonoid content, especially quercetin, contributes significantly to the antioxidant and anti-inflammatory effects. Shallot skin also shows effective antibacterial and antimicrobial activity against pathogenic strains such as Staphylococcus aureus, Escherichia coli, and Salmonella typhi. In addition, the mechanism of inhibition of α-amylase and α-glucosidase enzymes shows potential as an antidiabetic agent. Anticancer activity is supported by the active compounds' ability to induce apoptosis and inhibit cancer cell proliferation. With its abundant bioactive compound profile, shallot skin has the potential to be developed.
Co-Authors Afnan Septi Mulyani Afnan Septy Mulyani Afrizal Maulidan Rachmawan Agustin, Ayu Tri Ahmad Khoirul Azwar Alfarisi, Hilmi Pratama Alfi Nur Ramadhani Alfira Rosaliana Aliyah Purwanti Aliyah Purwanti Alvia Putri Priyono, Rosyidatul Amalia Wardatul Firdaus Ambari, Yani Anas, Mohammad Nizar Anggie Noviana Putri Anggitasari, Wima Anggraeni, Linda Suci Anggraeni, Lutvi Arista Wahyu Ningsih Arista Wahyuningsih Atmanegara, Stivani Yanti Aulia, Andira Aura Denaneer Mulya Aura Denaneer Mulya Avrillana Dewangi Gea Ayunda Diarso Ayu Angger Putri M. Soleh Ayu Dwi Wardani Ayu Tri Agustin Bekti Kusuma Primadani Damayanti, Mita Eka Damayanti, Selvi Danny Dwi F Danny Dwi Firmansyah Darrojah, Urfi Narva’u Dea Agita Anggraini Dea Maulidi Saputri DEWI RAHMAWATI Dewi, Novi Rosita Dhina Ayu Susanti Diah Yuli Pangesti Dina Trianggaluh Fauziah Dina Trianggaluh Fauziah Dinayah, Syafinatud Dinda Febri Puspitasari Dinda Febri Puspitasari Dwi Koko Pratoko Dyan Wigati Elisa wardatul awaliya Endang Lifchatullaillah Fadli Muhammad F Fadli Muhammad Fathoni Fadli Muhammad Fathony Fahrur Rozi Shodiqi Fendy Prasetyawan Fitria, Ayu Florentinus Dika Octa Riswanto Hafiz Achmad Hafiz Auni Iswanto Haris Agung Hartalina Mufidah Hasanah, Adinda Shofiatul Hasiseh Hasiseh HELMALIA HELMALIA, HELMALIA Heri Setyo Budi Hidayati, Sholihatil IGA Karnasih Indah Suciati Iski Weni Pebriarti Iski Weni Pebriarti Ismanti, Septie Putri Kanaya Dewayanti Khrisna Agung Cendekiawan lindawati setyaningrum Lisa Savitri M. Rofik Usman Maheswari, Anindya Dinarya Martina, Ina Michael Nicoin DC Michael Nicoin DC Mohammad Rofik Usman Mohammad Rofiq Usman Muhammad Alvin Yovansya Mu’affan, Achmad Adha Nabila, Talitha Vanian Nadia Khairun Nisa nafisah isnawati Nafisah Isnawati Nanda Pradwitha Fariansiska Neny Poerwahyuningrum Novyananda Salmasfattah Nur Hasanah Nurul Fathona Pangesti, Yuli Pebriarti, Iski Weni Permatasari, Shafira Restu Pramesti, Lita Aulia Puteri Shinta Putra, Zulkarnain Permana Putri Ramadani Putri Ramadhani Putri, Masitah Nurwidiya Qurrotul Aini Rahmadania Affelia Dianto Ramadhan Bagus Cahyono Ramadhan, Muhammad Ridho Ratna Amelia Ratna Amelia Ressi, Monica Risqi Wahyudi rofiqoh rofiqoh Sepbrilla Ananda Kusriadi Sholihatil Hidayati Sholihatil Hidayati Siti Aisyah Siti Hotima Siti Hotimah Siti Nur Maulita Siti Saidah Stevi R izky Anandha Susanti, Dhina Ayu Swastika, Melur Tri Taniya Tri Oktavia Ningrum Tuhfatul Hilmits T Tuhfatul Hilmits Tsania Ulum, Miftahol Wanda Tri Agustin Wardani, Ali Ridho Wardhani, Firdha Aprillia Wima Anggitasari Yola Kristina Cendani Yuneka Saristiana Zulkarnain Permana