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All Journal Jurnal Ilmiah Universitas Batanghari Jambi As-syifaa Jurnal Farmasi Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Biologi Tropis Manuju : Malahayati Nursing Journal Jurnal Medika Malahayati UMI Medical Journal PREPOTIF : Jurnal Kesehatan Masyarakat Indonesian Journal of Global Health research Jurnal Promotif Preventif Jurnal Kesehatan Tambusai Wal'afiat Hospital Journal Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) YASIN: Jurnal Pendidikan dan Sosial Budaya jpki Innovative: Journal Of Social Science Research WAL'AFIAT HOSPITAL JOURNAL JOURNAL OF Qualitative Health Research & Case Studies Reports
Rachmat Faisal Syamsu, Rachmat Faisal
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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PENGARUH KONSUMSI BUAH ANGGUR ISABELLA (VITIS LABRUSCA) TERHADAP PERUBAHAN TEKANAN DARAH KAJIAN LITERATUR REVIEW Syamsu, Rachmat Faisal; Azis, Arung Anugrah Al; Wahyuni, Astri
Jurnal Kesehatan Tambusai Vol. 6 No. 3 (2025): SEPTEMBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i3.49244

Abstract

Hipertensi merupakan faktor risiko utama penyakit kardiovaskular. Konsumsi pangan kaya polifenol, seperti anggur Isabella (Vitis labrusca), dilaporkan berpotensi menurunkan tekanan darah melalui mekanisme vasodilatasi, antioksidan, dan antiinflamasi. Kajian ini bertujuan mengevaluasi bukti ilmiah pengaruh konsumsi anggur Isabella terhadap tekanan darah. Literature review ini menelaah artikel dari PubMed, NCBI, dan Google Scholar (2017–2025) yang memenuhi kriteria: full text, akses terbuka, dan membahas efek konsumsi anggur Isabella terhadap tekanan darah. Analisis literatur menunjukkan konsumsi polifenol 200–800 mg/hari dari anggur Isabella menurunkan tekanan sistolik 4,7–13 mmHg, dengan efek lebih kuat pada penderita hipertensi dan prehipertensi. Bentuk ekstrak ultrasound dan nanoenkapsulasi meningkatkan bioavailabilitas hingga 3,2 kali dibanding buah segar atau jus. Durasi minimal empat minggu diperlukan untuk menghasilkan perubahan signifikan. Mekanisme meliputi: (1) inhibisi ACE yang mengurangi produksi angiotensin II dan vasokonstriksi, (2) peningkatan sintesis nitrit oksida (NO) melalui aktivasi eNOS yang memperbaiki fungsi endotel, (3) pengurangan stres oksidatif dengan menurunkan kadar malondialdehid (MDA) dan meningkatkan aktivitas enzim antioksidan seperti SOD dan katalase, serta (4) penurunan inflamasi vaskular melalui penurunan kadar CRP dan IL-6. Efek tambahan yang ditemukan meliputi perbaikan profil lipid dan penurunan kekakuan pembuluh darah. Anggur Isabella berpotensi menjadi intervensi nutraseutikal efektif dalam pengelolaan hipertensi melalui kombinasi mekanisme antihipertensi dan antioksidan. Uji klinis terkontrol diperlukan untuk menentukan dosis dan bentuk sediaan optimal. Kata kunci: hipertensi, Vitis labrusca, anggur Isabella, polifenol, tekanan darah.
Literature Review: The Effect of Extra Virgin Olive Oil (Olea europaea L.) on Pseudomonas aeruginosa Bacteria Domu, Anugrah Julistiar Aksan; Syamsu, Rachmat Faisal; Karim, Marzelina; Hadi, Santriani; Arfah, Arni Isnaini
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i3.1722

Abstract

Background: Olive oil, especially Extra Virgin Olive Oil (EVOO), which contains polyphenols and phytochemical compounds such as flavonoids and oleuropein, has long been utilized to enhance human health and exhibits potential antibacterial activity against Pseudomonas aeruginosa, an opportunistic pathogenic bacterium often responsible for severe infections and resistance to various antibiotics. Objective: To investigate the antibacterial properties of extra virgin olive oil (Olea europaea L.) against Pseudomonas aeruginosa. Method: A literature review study obtained from the internet, including theses, journals, textbooks, and e-books. The databases used were Google Scholar, Elsevier, ScienceDirect, and PubMed NCBI. Results: Extra Virgin Olive Oil (EVOO) demonstrates antibacterial activity against Pseudomonas aeruginosa based on findings from 10 journals. Bioactive compounds such as polyphenols, oleuropein, and hydroxytyrosol are effective against Pseudomonas aeruginosa through mechanisms that include inhibiting quorum sensing, damaging the cell wall, increasing membrane permeability, and inhibiting biofilm formation and virulence factors. Olive leaf extract and combinations with nanoparticles further enhance antibacterial effectiveness against resistant strains, making EVOO a potential natural antibacterial agent. Conclusion: Olive oil, particularly Extra Virgin Olive Oil (EVOO), contains bioactive compounds such as oleacein, oleocanthal, polyphenols, flavonoids, oleuropein, and hydroxytyrosol, which exhibit significant antibacterial activity against Pseudomonas aeruginosa.
Asuhan gizi pada penderita hipertensi di layanan primer: Literatur review Syamsu, Rachmat Faisal; Abdullah, A. Adila Permata; Mubarok, Rizqi; Nurdin, Abbas Zavey; Dahlia, Dahlia; Nasruddin, Hermiaty
JOURNAL OF Qualitative Health Research & Case Studies Reports Vol 5 No 4 (2025): September Edition 2025
Publisher : Published by: Indonesian Public Health-Observer Information Forum (IPHORR) Kerjasama dengan Persatuan Perawat Nasional Indonesia (PPNI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/quilt.v5i4.1069

Abstract

Background: Hypertension is one of the most common chronic medical conditions characterized by persistently elevated arterial pressure. Hypertension has been one of the most studied topics in the past century and has become a significant comorbidity contributing to the development of stroke, myocardial infarction, heart failure, and kidney failure. Purpose: To determine nutritional care for patients with hypertension in primary care. Method: This literature review was conducted by searching, summarizing, and drawing conclusions from various previous studies. The search was limited to the period 2020 to 2025 using databases such as Sinta. The literature obtained was searched using the keywords "Gynamic Status" and "Hypertension" in both English and Indonesian. Results: A total of 10 journals were reviewed that discussed nutritional care for patients with hypertension. Conclusion: The majority of the reviewed journals showed a relationship between nutritional intake and hypertension.   Keywords: Hypertension; Nutritional Status.   Pendahuluan: Hipertensi termasuk dalam kondisi medis kronis yang paling umum yang ditandai dengan peningkatan tekanan arteri yang terus-menerus. Hipertensi telah menjadi salah satu topik yang paling banyak dipelajari pada abad sebelumnya dan telah menjadi salah satu komorbiditas paling signifikan yang berkontribusi terhadap perkembangan stroke, infark miokard, gagal jantung, dan gagal ginjal. Tujuan: Untuk mengetahui asuhan gizi pada penderita hipertensi pada layanan primer. Metode: Penelitian tinjauan pustaka dengan mencari, merangkum, dan menarik kesimpulan dari berbagai studi literatur terdahulu yang dicari dan dibatasi dari tahun 2020 hingga 2025 dengan menggunakan database seperti Sinta. Literatur yang didapatkan dicari dengan menggunakan kata kunci “Status Gizi”, “Hipertensi”, baik dalam Bahasa Inggris maupun Bahasa Indonesia. Hasil: Sebanyak 10 jurnal yang telah direview yang membahas mengenai asuhan gizi pada penderita hipertensi Simpulan: Mayoritas dari jurnal yang telah direview menunjukan bahwa terdapat hubungan pada asupan gizi dengan penderita hipertensi   Kata Kunci : Hipertensi; Status Gizi.
The Relationship Between Personal Hygiene and Economic Level on The Incidence of Scabies in Nur El Haq Modern Islamic Boarding School Students Yusuf, Andini; Hadi, Santriani; Murfat, Zulfitriani; Syamsu, Rachmat Faisal; Makmun, Armanto
Jurnal Biologi Tropis Vol. 24 No. 1 (2024): Januari - Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1.6503

Abstract

The study, entitled " The relationship between personal hygiene and economic level on the incidence of scabies in Nur El Haq modern Islamic boarding school students". was conducted from November 2023 to January 2024. This study aims to determine the relationship of personal hygiene and economic level to the incident of scabies. This research analytical observational method with a cross sectional approach then analyzed through the Chi-Square test using the SPSS application. Based on the results of research with statistical tests obtained regarding personal hygiene and the incidence of scabies, p value of 0.029 < 0.05 was obtained, and there is no significant relationship between economic level and the incidence of scabies as shown by the p-value 0.176 <0.05. Students at the Nur El Haq modern Islamic boarding school with poor personal hygiene are more susceptible to scabies. Further research is needed regarding other variables related to scabies incidents among students at boarding school. The results of this research can be used as a reference for educating students about the importance of personal hygiene for health.
Total Cholesterol and Triglyceride Levels after Giving Olive Oil and Fig Fruid Extract Against Rattus Novergicus With High-Fat Diet Sulastri, Evi; Syamsu, Rachmat Faisal; Karim, Marzelina; Royani, Ida; Karim, Abdul Mubdi Ardiansar Arifuddin
Jurnal Biologi Tropis Vol. 24 No. 1 (2024): Januari - Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1.6527

Abstract

The reserach entiled “Changes in total cholesterol levels and trigelyceride levels after administration of olive oil and fig leaf extract“ was conducted from July to September 2023. This study aims to determine changes in total cholesterol levels and triglyceride levels when given olive oil and fig friut extract to white mice on a high-fat diet. This research method use an experimental quantitative research type with a pretest-posttest control group research design then analyzed through statistical analysis test using the Microsoft Office Excel 2013 application. Based on the results of study, constant result was obtained for total cholesterol in all treatment groups, namely 86.5 mg/dL and significant results were obtained in reducing triglycerides in the olive oil treatment group and the combination of olive oil and fig fruit extract, namely in the group given olive oil of 170.5 mg. /dL (81.19%), in the group given a combination of fig fruit extract it was 43.75 mg/dL (38.55%), and the increase in the group given fig fruit extract was 38 mg/dL (29.92%). The combination of olive oil and fig fruit extract has a constant effect on total cholesterol levels and reduces triglyceride levels. Fig fruit extract has a constant effect on total cholesterol levels and increases triglyceride levels. Olive oil has a constant effect on total cholesterol levels and more significant results in reducing triglyceride levels in mice with high-fat feed in all treatment groups.
Changes HDL and LDL Levels After Using Olive Oil and Figs Extract on White Rats with A High-Fat Diet Alhumaerah, Musdalifah; Syamsu, Rachmat Faisal; Karim, Marzelina; Nurmadilla, Nesyana; Murfat, Zulfitriani
Jurnal Biologi Tropis Vol. 24 No. 1 (2024): Januari - Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1.6536

Abstract

Hypercholesterolemia often initiates the pathogenesis of atherosclerosis which can occur slowly. As free radicals increase, the need for antioxidants also increases. Reducing LDL and increasing HDL levels is the target of therapy for hyperlipidemia patients with the main goals of lifestyle changes and drug therapy. Olive oil and fig extract have therapeutic benefits as alternative treatments from MUFA content dominated by oleic acid and phenolic compounds. The polyphenol content is known to inhibit the formation of atherosclerosis and inhibit the increase in MCP-1 levels in white mice on a high-fat diet. Therefore, it is hoped that the administration of figs extract and olive oil can overcome dyslipidemia, especially changes in HDL and LDL levels in white mice. To determine changes in HDL and LDL levels. The research conducted was a true experimental research was used with a Pre-Post control group research design and test statistical analysis with Microsoft Office 2013. Showed there was an effect of fig extract (Ficus Carica L) on changes in HDL levels and the effect of olive oil (Olea europea L) on changes in LDL levels in white rats (Rattus novergicus) fed a high-fat diet. The intervention of fig extract and olive oil had a significant effect on the group given the single intervention.
Relationship between Prayer Intensity and Anxiety Levels among Medical Students at Muslim Indonesian University Sakti, Muhammad Reyhan; Abdullah, Rezky Putri Indrawati; Wello, Eny Arlini; Mukhtar, Shulhana; Syamsu, Rachmat Faisal
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.6984

Abstract

In the dynamic environment of Indonesian universities, students, particularly those in the medical field, face a crucial juncture of personal growth amid academic rigor. This transition from youth to adulthood brings with it not only academic challenges but also psychological hurdles, notably anxiety. While anxiety is a common human experience, it can impede a student's ability to thrive. However, within the context of Indonesian culture, prayer serves as a powerful tool for mental well-being. Studies have indicated its potential to alleviate anxiety and foster a sense of calmness. Thus, this research endeavors to explore the relationship between prayer intensity and anxiety levels among the 2021 cohort of medical students at the Muslim University of Indonesia, shedding light on the intersection of spirituality and mental health in academic settings. The study revealed that the majority of the 2021 cohort of medical students at Muslim University of Indonesia are 21 years old (54.8%), predominantly female (76.7%), with most exhibiting good prayer intensity (49.3%) and normal anxiety levels (74%). Additionally, Chi-Square analysis indicated a significant relationship between prayer intensity and anxiety levels among these students (p = 0.005<0.05). The study findings indicate that the sampled 2021 medical students at Muslim University of Indonesia exhibit good prayer intensity and normal anxiety levels. Moreover, there's a significant relationship between prayer intensity and anxiety levels among these students.
The Effect of Olive Oil and Tin Leaf Extract on GDP Levels in White Rats Jannah, Reza Miftahul; Syamsu, Rachmat Faisal; Karim, Marzelina; Julyani, Sry; Kartika, Andy Visi
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7293

Abstract

Diabetes Mellitus is a chronic condition characterized by fasting blood glucose levels of less than 126 mg/dl, which are above the normal range. DM is otherwise called the quiet executioner since it is frequently not understood and when it is found complexities have happened. Monounsaturated fatty acids (MUFA), which have anti-diabetic properties, can be found in olive oil, a functional food. Fig leaves contain flavonoid compounds, β-setosterol, and these polyphenols are accounted for to work as antidiabetics. The point of this study was to decide the impact of directing olive oil and fig leaf separate on fasting blood glucose levels in white rodents. This study employs a Pretest-Posttest Control Group Design and quantitative experimental research methods. The examples utilized were 24 mice. The independent t-test was used to process the results, and One Way Annova was used to carry on. According to the findings of the study, the group that received olive oil had a fasting blood glucose of 41.00 mg/dL (p0.004), the group that received fig leaf extract had a p value of 37.25 mg/dL (p0.005), and the group that received a mixture of olive oil and fig leaf extract had a p value of 39.00 mg/dL (p0.004). Olive oil and fig leaf extract both have an effect on the blood glucose levels of mice induced by Aloxan, but the combination yields more significant results. This is the study's conclusion.
Co-Authors 'Aisy S.Day, Siti Rahadatul Abdillah, Andi Rachmat Abdullah, A. Adila Permata Abdullah, Rezky Putri Indrawati Ahmad Ahmad Akbar, Muhammad Alief Alfaruq, Zulfi Zain Alhumaerah, Musdalifah Alie, Nuzul Shafira Ancha, Annisa Andry Pratama, Andry Arfah, Arni Isnaini Astri Wahyuni Azis, Arung Anugrah Al Bazith, Akhmad Bima, Irmayanti Johar Dahlia Dahlia Domu, Anugrah Julistiar Aksan Evi Sulastri Fattah, Nurfachanti febriyanti febriyanti Gani, Azis Beru Hadi, Santriani Hazminafni, Nur Zahra Noor Khaerani Ida Royani Ikram, Dzul Indarwati Abdullah, Rezky Putri Jam’an Laoh, Abulkahiril Jannah, Reza Miftahul Jaya, Muh. Alim Juliani, Sri Julyani, Sry Karim, Abdul Mubdi Ardiansar Arifuddin Karim, Marzelina Kartika, Andy Visi Lausiri, Satharia Makmun, Armanto Mamile, Rahmawati Mappaware, Nasrudin Andi Maulidiah, Nurul Farah Mayo, Abbas Ali Mochammad Erwin Rachman, Mochammad Erwin Mochtar, Shulhana Mokhtar, Shulhana Mubarok, Rizqi Mukhtar, Shulhana Musa, Inna Mutmainnah N. Hamzah, Pratiwi Nasruddin, Hermiaty Nawawi, Nurafni Maharani Nurdin, Abbas Zavey Nurhikma, Nurhikma Nurmadilla, Nesyana Ode Arli, Rosmelidian Safari Pramono, Sigit Dwi Purnamasari, Reeny Putri, Riski Astriani Rachman, Moch. Erwin Rafiqah, Rafiqah Rahman, Dinda Briliany Rahman, Mochammad Erwin Rizki Salsabilah R, Andi Fatihah Saifullah, Yayan Yustika Sakti, Muhammad Reyhan Saputra, Adrian Shamad, Muhammad Ishaq Sholehah, Mar'atun Siska Nuryanti, Siska Surdam, Zulfiyah Suryo, Ersya Putri Alifya Tebi, Tebi Thahir, Ilyas Utami, Nurfika Wello, Eny Arlini Yusuf, Andini Zulfitriani Murfat