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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Hearty : Jurnal Kesehatan Masyarakat Journal Health & Science : Gorontalo Journal Health and Science Community UMI Medical Journal PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Promotif Preventif Jurnal Kesehatan Tambusai JOURNAL LA MEDIHEALTICO Jurnal EduHealth Journal of Aafiyah Health Research (JAHR) Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Formosa Journal of Science and Technology (FJST) jpki Jurnal Mahasiswa Ilmu Kesehatan Fakumi Medical Journal The International Journal of Medical Science and Health Research The Indonesian Journal of General Medicine CHI JOURNAL OF Community Health Issues Jurnal Balireso: Jurnal Pengabdian pada Masyarakat
Darariani Iskandar
Universitas Muslim Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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POTENSI EKSTRAK BUNGA ROSELLA (HIBISCUS SABDARIFFA) SEBAGAI ANTIHIPERGLIKEMIA PADA TIKUS WISTAR HIPERGLIKEMIK: STUDI IN VIVO Akbar, M. Ali; Dahliah, Dahliah; Iskandar, Darariani; Wahyu, Sri; Nurhayati, Riski
Journal Health & Science : Gorontalo Journal Health and Science Community Vol 10, No 1 (2026): JANUARI: JOURNAL HEALTH AND SCIENCE : GORONTALO JOURNAL HEALTH AND SCIENCE COMM
Publisher : Gorontalo State University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/gojhes.v10i1.37584

Abstract

Diabetes melitus merupakan masalah kesehatan global dengan prevalensi yang terus meningkat dan memerlukan pengembangan terapi alternatif berbasis bahan alam. Bunga rosella (Hibiscus sabdariffa) diketahui mengandung berbagai senyawa bioaktif yang berpotensi memiliki efek antihiperglikemik. Kebaruan penelitian ini terletak pada evaluasi efektivitas ekstrak etanol bunga rosella dengan variasi dosis terhadap penurunan kadar glukosa darah pada model tikus Wistar hiperglikemik yang diinduksi streptozotocin. Penelitian ini bertujuan menganalisis potensi ekstrak etanol bunga rosella sebagai agen antihiperglikemik serta menilai pengaruh variasi dosis terhadap penurunan kadar glukosa darah. Metode yang digunakan adalah penelitian eksperimental laboratoris dengan desain pre test–post test control group design menggunakan 30 ekor tikus Wistar jantan hiperglikemik (GDS 200 mg/dL) yang diinduksi streptozotocin (STZ) 50 mg/kgBB dan dibagi menjadi lima kelompok, yaitu kontrol negatif (Na-CMC 0,5%), kontrol positif (metformin 150 mg/kgBB), serta tiga kelompok perlakuan ekstrak rosella dosis 100, 200, dan 400 mg/kgBB selama 15 hari, dengan pengukuran kadar glukosa darah sewaktu setiap tiga hari dan analisis data menggunakan Paired Sample T-Test, One Way ANOVA, dan Post Hoc Tukey (p0,05). Hasil penelitian menunjukkan seluruh kelompok perlakuan mengalami penurunan kadar glukosa darah yang signifikan (p0,05) dengan mean difference tertinggi pada kelompok P3 (226,83 mg/dL), diikuti P2 (192,50 mg/dL) dan P1 (137,83 mg/dL), serta uji ANOVA menunjukkan perbedaan bermakna antar kelompok sejak hari ke-3 hingga hari ke-15 (p0,05). Uji Post Hoc menunjukkan dosis 400 mg/kgBB memberikan efek penurunan glukosa paling optimal (101,8 ± 4,9 mg/dL) bahkan melampaui kelompok metformin (143,3 ± 6,3 mg/dL). Kesimpulan bahwa ekstrak etanol bunga rosella memiliki efektivitas antihiperglikemik yang bersifat dosis-tergantung pada tikus Wistar hiperglikemik, dengan dosis 400 mg/kgBB menunjukkan efek paling optimal.
“Characteristics of Upper Gastrointestinal Tract Patients Undergoing Endoscopic Examination at Ibnu Sina Hospital, Makassar.” AB, Tarisya Febriyanti Baso; Kanang, Indah Lestari Daeng; Sodiqah, Yani; Hidayati, Prema Hapsari; Iskandar, Darariani
Syifa'Medika Vol 16, No 2 (2026): Syifa Medika: Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v16i2.9992

Abstract

Disorders of the upper gastrointestinal tract, such as heartburn, bleeding, and difficulty swallowing, are often experienced by many patients. Endoscopy is an important procedure in diagnosing disorders of the upper gastrointestinal tract. Ibnu Sina Hospital in Makassar routinely performs endoscopy on patients with these complaints, but data on the characteristics of patients undergoing this procedure in 2023 is not widely available. This study used a descriptive design with a cross-sectional approach. The sample consisted of 260 patients who underwent endoscopy for upper gastrointestinal complaints at Ibnu Sina Hospital in Makassar in 2023. Data were collected through patient medical records, which included demographic information, main complaints, and diagnoses found after endoscopy. The results showed that heartburn was the most common complaint (61.2%), followed by upper gastrointestinal bleeding (28.5%) and difficulty swallowing (5%). Gastritis was found to be the most common diagnosis (30.4%), followed by esophagitis and GERD (21.2%). Demographic factors such as age, gender, education, and occupation influenced the distribution of the disease. This study emphasizes the importance of a holistic approach in treating patients with upper gastrointestinal disorders, taking into account social, economic, and lifestyle factors. In addition, early detection through endoscopy needs to be improved to identify gastrointestinal problems more effectively.
Characteristics Of Patients With Deep Vein Thrombosis At Ibnu Sina Hospital Makassar During The Period 2023-2024 Alya Anggriani; Reeny Purnamasari Juhamran; Tirta Swarga; Berry Erida Hasbi; Darariani Iskandar
Saintika Medika : Jurnal Ilmu Kesehatan dan Kedokteran Keluarga Vol. 21 No. 2 (2025): December 2025
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol21.SMUMM2.42221

Abstract

Introduction: Deep vein thrombosis (DVT) s the formation of blood clots in deep veins, commonly in the lower extremities. According to Virchow’s triad, blood flow stasis, hypercoagulability, and vascular damage contribute to its occurrence. This study aims to determine the characteristics of DVT patients at Ibnu Sina Hospital in Makassar during the period 2023–2024. Methods: A descriptive design with a mixed method (medical records and interviews) conducted at Ibnu Sina Hospital, Makassar, during the period 2023–2024. Used was total sampling of patients diagnosed with DVT. Data were processed using Microsoft Excel to produce frequency distributions and percentages. The Results: Most patients were aged 61–70 years (41%) and male (65%). The most common risk factors were prolonged bed rest (72%) due to stroke, femur fracture, heart failure, type 2 diabetes mellitus, acute renal failure, and osteoarthritis, followed by malignancy (24%) including breast, cervical, liver, and colorectal cancer. No patients with a history of DVT were found. The most common clinical symptom was leg swelling (47%). Conclusion: DVT at Ibnu Sina Hospital in Makassar was more common in the elderly, males, with prolonged bed rest as the main risk factor and malignancy as the second factor. Therefore, early mobilization, monitoring of risk factors, and more complete medical record keeping are necessary for the prevention of DVT.
Variasi Musiman Demam Tifoid di Kota Makassar: Analisis Deret Waktu Berbasis Data Sentinel Pediatrik dan Implikasinya terhadap Kesiapsiagaan Layanan Penyakit Dalam Dewasa Darariani Iskandar
Jurnal Promotif Preventif Vol 9 No 1 (2026): Februari 2026: JURNAL PROMOTIF PREVENTIF
Publisher : Fakultas Kesehatan Masyarakat Universitas Pancasakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47650/jpp.v9i1.2561

Abstract

Demam tifoid merupakan penyakit infeksi endemik di Indonesia yang masih memberikan beban signifikan terhadap layanan kesehatan. Variasi musiman diketahui berperan penting dalam dinamika transmisi tifoid, terutama di wilayah perkotaan. Penelitian ini bertujuan untuk menganalisis pola variasi musiman kejadian demam tifoid di Kota Makassar berdasarkan data sentinel populasi pediatrik serta implikasinya terhadap kesiapsiagaan layanan penyakit dalam dewasa. Penelitian ini menggunakan desain observasional deskriptif retrospektif dengan pendekatan analisis deret waktu terhadap seluruh kasus demam tifoid (ICD-10: A01.0) yang tercatat di RSIA Ananda Makassar selama periode Januari–Desember 2025. Hasil penelitian menunjukkan bahwa dari 376 kasus demam tifoid yang dianalisis, sebanyak 54,8% memerlukan perawatan rawat inap. Distribusi kasus memperlihatkan pola variasi musiman bimodal dengan puncak kejadian pada bulan April serta September–Oktober. Selain itu, rasio rawat inap terhadap rawat jalan meningkat pada periode puncak musiman, yang mengindikasikan kecenderungan derajat keparahan penyakit yang lebih tinggi. Adapun kesimpulan dari penelitian ini bahwa kejadian demam tifoid di Kota Makassar menunjukkan variasi musiman yang jelas. Lonjakan kasus pada populasi pediatrik berpotensi dimanfaatkan sebagai indikator sentinel dalam sistem peringatan dini serta untuk meningkatkan kesiapsiagaan layanan penyakit dalam dewasa di wilayah endemis.
Pengetahuan ketahanan pangan dan gizi berbasiskomunitas di masyarakat perkotaan Indonesia: Penerimaan program promosi kesehatan berbasis masjid Fadli Ananda; Darariani Iskandar; Irwan Ashari; Faisal Rizal Zaenal; Irma Irma
JOURNAL OF Community Health Issues Vol. 3 No. 3 (2026): August Edition 2026
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR) Kerjasama dengan Ikatan Perawat Kesehatan Komunitas Indonesia (IPKKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/chi.v3i3.4384

Abstract

Background: Food security and nutrition knowledge are important components of public health promotion, particularly when health education is delivered through community settings rooted in local culture. Religious institutions such as mosques can provide accessible settings for integrating health education with community engagement. However, evidence regarding participants’ knowledge and acceptance of mosque-based health promotion activities remains limited. Purpose: This study aimed to describe participants’ knowledge of food security and nutrition and their acceptance of a mosque-based community health promotion program. Method: A quantitative descriptive study using a cross-sectional evaluation approach was conducted among 23 community participants who attended a mosque-based health promotion activity. Data were collected using a 17-item knowledge questionnaire consisting of 10 food security items and seven nutrition items, along with eight five-point Likert-scale items assessing program acceptance. Descriptive statistics were used to summarize participant characteristics, item-level knowledge, knowledge scores, and acceptance ratings. Results: The participants had a mean age of 54.48 ± 11.75 years, ranging from 29 to 76 years, and most were involved in household management (69.6%). The mean food security knowledge score was 8.04 ± 1.77 out of 10, while the mean nutrition knowledge score was 5.22 ± 1.48 out of 7. The overall mean knowledge score was 13.26 ± 2.60 out of 17. Knowledge gaps were primarily observed in identifying the components of food security, sustainable agriculture, the recommended proportion of vegetables and fruits according to Isi Piringku (My Plate), and the recommended duration of physical activity. Program acceptance was high, with an overall mean rating of 4.67 ± 0.65 on a five-point scale. The mosque as a setting for health promotion received a mean rating of 4.61 ± 0.72, with 95.7% of participants giving a rating of 4 or 5. Conclusion: Participants demonstrated relatively high levels of food security and nutrition knowledge and good acceptance of the mosque-based community health promotion program. These findings support the potential acceptability of mosque-based settings for integrating food security and nutrition education into community health promotion. Further studies involving larger samples, validated instruments, and pre–post or controlled designs are needed to assess changes in knowledge and determine program effectiveness.
The Relationship Between Body Mass Index and Primary Genu Osteoarthritis in the Elderly at YW-UMI “Ibnu Sina” Hospital in 2022–2024 Fahira Nida Alzahra; Imran Safei; Iin Widya Ningsi; Darariani Iskandar; Fadil Mula Putra
Jurnal Mahasiswa Ilmu Kesehatan Vol. 4 No. 2 (2026): Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v4i2.3906

Abstract

Osteoarthritis (OA) is one of the most common degenerative joint disorders, particularly affecting the elderly population and frequently involving the knee joint (primary genu OA). Body Mass Index (BMI) is widely recognized as a modifiable risk factor that may contribute to the development of osteoarthritis. In Makassar, the prevalence of primary genu OA has continued to rise, especially among older adults with a BMI of ≥25 kg/m². This study aimed to examine the relationship between Body Mass Index (BMI) and the incidence of primary genu osteoarthritis among elderly patients at Ibnu Sina Hospital YW-UMI Makassar during the period of 2022–2024. This research used a quantitative cross-sectional design involving 50 elderly respondents, consisting of 25 patients diagnosed with primary genu OA and 25 patients without OA. Data were obtained from medical records, including variables such as age, BMI, and osteoarthritis status. Univariate analysis was used to describe respondent characteristics, while bivariate analysis with the Fisher Exact test was performed to evaluate the relationship between BMI categories and the occurrence of OA. The findings indicated that most respondents were aged 60–69 years (48%). The majority had BMI values categorized as normal (52%) and overweight (36%). The proportion of respondents with OA and without OA was equal, each accounting for 50% of the sample. Statistical analysis demonstrated that there was no significant relationship between BMI and the incidence of primary genu osteoarthritis (p = 0.46). The study concludes that BMI was not significantly associated with the occurrence of primary genu osteoarthritis in the study population. Nevertheless, maintaining a healthy body weight remains important for the prevention and management of osteoarthritis among the elderly.
Co-Authors A. Husni Tanra A. Muh. Akbar Batara Putra A.M AB, Tarisya Febriyanti Baso Abdi, Dian Amelia Akbar, M. Ali Alya Anggriani Ameliah, Nabila Ardiyanto Ardiyanto Arifin Bando, Achmad Syafii Asram, Andi Aulia, Aulia Berry Erida Hasbi Bulkis Natsir Dahliah, Dahliah Dirgahayu, A. Millaty Erick Gamaliel Amba Fadhila Fadhila Fadil Mula Putra Fadli Ananda Fadya, Atiqa Fahira Nida Alzahra Faisal Rizal Zaenal Febie Irsandy Syahruddin Gayatri, Sri Wahyuni Hamzah, Pratiwi Nasir Hamzah, Pratiwi Natsir Handayani, Prema Hapsari Hasan Hasan Hasan Hendrian Chaniago Iin Widya Ningsi Imran Safei Indah Lestari Daeng Kanang Indarwati Abdullah, Rezky Putri Irma Irma Irsandy Syahruddin, Febie Irwan Ashari Kanang, Indah Lestari Daeng Maharani, Ratih Natasha Mokhtar, Shulhana Muh. Fadil Asrar Muhammad Ikhsan Muhammad Imran Mulyadi, Farah Ekawati Nur, Muh Jabal Nurhayati, Riski Nurinayah, A.Nabila Nurlana Zamaun Nurmadilla, Nesyana Nurtania, Ariyanie Pangerang, Andi Fatika Sari Pramono, Sigit Dwi Purnamasari, Reeny R. Bamahry, Aryanti Rachmat Faisal Syamsu, Rachmat Faisal Rahmawati, Rahmawati Razak, Kaisar Reeny Purnamasari Reeny Purnamasari Juhamran Safitri, Asrini Sodiqah, Yani Sommeng, Faisal Sri Irmandha K Sri Rahmayanti Limatahu Sri Vitayani Sri Wahyu St. Khairunnisa Syarif Suryo, Ersya Putri Alifya Syarif Hidayatullah Syarifuddin Wahid Tirta Swarga Vikram, Muh Wello, Eny Arlini Wello Wibowo, Suchika Aisyah Yanti, Andi Kartini Eka Yuniarizka, Sekila Yuniarti, Lisa Zulkifli, Andi Aldita Nitamapia