Article Per Year (5 Year)
p-Index From 2021 - 2026
6.002
P-Index
This Author published in this journals
All Journal Indonesian Journal of Pharmaceutical Science and Technology Mutiara Medika: Jurnal Kedokteran dan Kesehatan Jurnal Kedokteran dan Kesehatan Jurnal Kedokteran Anatomica (Anatomica Medical Journal) JURNAL IBNU SINA BIOMEDIKA Buletin Farmatera Hasil Pengabdian Kepada Masyarakat Sarwahita : Jurnal Pengabdian Kepada Masyarakat Jurnal Aisyah : Jurnal Ilmu Kesehatan JURNAL ILMIAH MAKSITEK JURNAL ILMIAH SIMANTEK JURNAL ILMIAH KOHESI Budapest International Research in Exact Sciences (BirEx Journal) Jurnal Implementa Husada ABDI SABHA (Jurnal Pengabdian kepada Masyarakat) DedikasiMU: Journal of Community Service Community Medicine and Education Journal Journal of Social Research Empowerment: Jurnal Pengabdian Masyarakat Indonesian Journal of Cancer Jurnal Salingka Abdimas Eduvest - Journal of Universal Studies PROSIDING SEMINAR NASIONAL PENELITIAN DAN PENGABDIAN KEPADA MASYARAKAT (SNPPM) UNIVERSITAS MUHAMMADIYAH METRO Jurnal Pandu Husada Biomedika
Humairah Medina Liza Lubis
Universitas Muhammadiyah Sumatera Utara
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Transportation Veterinary Other

Published : 54 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Journal of Social Research

 1 
The Effect of Arabica Coffee Extract ( Coffea Arabica L.) on the Progression of Lactobacillus Cervicovaginal Microbiome Biomarkers Farisha Firzana; Humairah Medina Liza Lubis
Journal of Social Research Vol. 5 No. 1 (2025): Journal of Social Research
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/josr.v5i1.2894

Abstract

Cervical infection or cervicitis is an inflammation of the cervical epithelium that can progress to chronicity and potentially lead to cervical cancer. Lactobacillus crispatus, which is normal vaginal flora, can migrate to the cervix and cause inflammation. Mandailing arabica coffee (Coffea arabica L.) is rich in phenolic compounds and antioxidant activity, with antibacterial potential. This research aims to assess the effect of Mandailing arabica coffee (Coffea arabica L.) extract on the growth of Lactobacillus crispatus as an effort to reduce the progression of cervicovaginal microbiome biomarkers. This laboratory experimental study used a completely randomized design (CRD) with 25%, 50%, and 100% concentrations of Mandailing arabica coffee extract. The antibacterial activity test was carried out by liquid dilution, solid dilution, and disc diffusion methods. Data were analyzed using a one-way ANOVA test followed by the Least Significant Difference post hoc test. Mandailing arabica coffee extract contains alkaloids, flavonoids, saponins, tannins, and triterpenoids. Liquid and solid dilution tests showed inhibition of Lactobacillus crispatus growth at all extract concentrations. The disc diffusion test produced the greatest average inhibition at 100% concentration (6.62 cm), followed by 50% (5.19 cm), and 25% (4.81 cm). ANOVA analysis showed a significant effect of extract administration on the growth of Lactobacillus crispatus (p < 0.001). Mandailing arabica coffee (Coffea arabica L.) extract has antibacterial activity against Lactobacillus crispatus, with growth inhibition increasing alongside increasing extract concentration. This indicates the potential of Mandailing arabica coffee in preventing cervical inflammation and the progression of precancerous lesions. 
Co-Authors Afelita, Tia Afif Fadhilah Irsyad Afifah Endah Dwi Purianti Aini, Rahma Ainur Rofiq Ainur Rofiq Aisyah Salsabila Alamsyah, Tegar Alfarisi, Bunail Isna Amanda Farra Assyfah Aminuyati Amira Fazhira Ance Roslina ANNISA . ANNISA FITRI HENDEWI Annisa Rifqa Hestiana Annissa Ambaravista Nasution Anriani, Dwi Arifin, Salsalina Dwi Atika Dwiyanti Atika Rahmi Atmaja, Pramudia Barasa, Neza Farach Addiba Berkah Tania Sawitri Bunail Isna Alfarisi Ceri Permata Ayuni Charisma Yani Roza Cindy, Tiara Safira Cindykia, Assyifa DEA YULIA LUBIS Delyuzar, Delyuzar Des Suryani DEWI AGUSTIN HAKIM HARAHAP Dilma Ayu Khairani DIWA AULIA AHMAD Dwiyanti, Atika Fadillah, Akram Fadlina, Shofiah Dina Farisha Firzana Fayyaza, Nesya Alya Febryandani, Silvy Claresta Filzah, Rahmah Fitri Nur Malini Frina Aeni Putri Galang Ramadhan Hasanah, Nurul HENDRA SUTYSNA Herian, M. Fauzan Alfatin Hervina, Hervina Hestiana, Annisa Rifqa Hidayatullah, Muhammad Rafli HSB, Fatur M Ahmad Hutabarat, Siti Rahmah IBNU AFIF ARMADI Ilham Hariaji Imanda Jasmine Siregar Indra, Kirana Arum Indyra Mahrani Lubis Irsyad, Afif Fadhilah Islami, M. Dian Isnaini Ulfa Jamilah, Qurratu Kasturi KARTIKA HANDAYANI Kesuma, Ilham Jaya KHAIRATUL FITHRIYAH Khairunisa, Zafira Kirana Arum Indra Laden Laden, Laden LITA SEPTINA Lubita, Mardiyah M. Dian Islami Malini, Fitri Nur MEIZLY ANDINA Muhammad Al Anas Muhammad Farouq Hilmi Harahap Muhammad Fathurridha Arabia Salim Muhammad Rafli Hidayatullah Muhammad Zikri Agung Ramadhan Muhammad Zulfikar Karim Chan Nasution, Annissa Ambaravista Nasution, Reyhan Khaira Helmita Nesya Alya Fayyaza Noviardy, Arya Nurcahaya Sinaga Nurfadly, Nurfadly Oche Axena Yulhan Parinduri, Saskya Nabila Prayoga, M. Iqbal Purwiningsih, Emni Purwoningsih, Emni Qatrunnada Medina Salim Qatrunnada Medina Salim Rafa Nabila Haifa Rafa Nabila Haifa Rahma Rifda F.S. Lubis Rahmah Filzah Raihana Zavira Ramadhan, Galang Ramadhan, Reza Mukti Ratih Yulistika Utami Refangga Sudi Wardana Riaulina, Nasha RIFQY IMSYA AL AYYUBI LUBIS Rizkitha Martono Putri Rizky Yusfasari Robitah Asfur Salsabila, Aisyah Salsabila, Asya Salsabila, Salsabila Sari, Indah Permata Sembiring, Khairul Rasyid Septiady, Teuku Baihaqi Setiadi, Nurlina Shaik Hussain, Basrah Bee Binte SITI MIRHALINA Siti Mulyani Sitompul, Asma Dwi Nantika Sri Rezeki Arbaningsih SYAFINA, IKHFANA Tania Mulia Utami Tegar Alamsyah Teuku Baihaqi Septiady USWATUL KHOIROT Utami, Tania Mulia Widya Yustika Yulhan, Oche Axena Yuliansyah, Putri Ridha Yusmawati Yusran Yustika, Widya Zavira, Raihana Zulkarnain, Rizki Chairani