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All Journal JURNAL GIZI INDONESIA Jurnal Penelitian Pendidikan IPA (JPPIPA) Syntax Literate: Jurnal Ilmiah Indonesia Window of Health : Jurnal Kesehatan Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal Ilmiah Farmako Bahari Science Midwifery Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan) Jurnal Farmasi dan Sains Indonesia (JFSI) JOURNAL LA MEDIHEALTICO Jurnal Ilmiah Bakti Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian Praeparandi : Jurnal Farmasi dan Sains Jurnal Farmasi Indonesia Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Journal of Public Health and Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian
Zuniarto, Ahmad Azrul
Sekolah Tinggi Farmasi YPIB Cirebon
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Journal : Science Midwifery

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The role of honey, curcuma, and black cumin supplements in overcoming stunting on the adaptive immune system Sabarudin, Cecep; Hasimun, Patonah; Kusriani, Herni; Zuniarto, Ahmad Azrul; Pandanwangi, Siti; Fatmawati, Eva; Afief, Arief R.; Sodik, Jajang Japar
Science Midwifery Vol 13 No 5 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i5.2185

Abstract

Stunting is strongly associated with impaired immune function, as chronically malnourished children tend to have weaker immunity and are more vulnerable to infection. This study aimed to examine the effect of temulawak–black cumin herbal honey on the adaptive immune system in stunted children. A quasi-experimental one-group pre-test and post-test design was used. The findings showed that the intervention significantly increased height-for-age (TB/U) in the treatment group compared to the control group (p = 0.014). Weight-for-age (BB/U) also rose significantly within the treatment group (p = 0.013), but no significant difference was found relative to the control group (p = 0.192). The supplement significantly elevated IgM levels in the treatment group (p = 0.001), though again without a significant difference from the control (p = 0.546). CD4 concentration decreased in the treatment group (p = 0.003), but the change was not significantly different from the control (p = 0.682). In conclusion, temulawak–black cumin herbal honey can improve nutritional status and enhance adaptive immunity by increasing IgM levels, although it does not raise CD4 levels and instead slows CD4 decline. However, its effectiveness in increasing IgM and CD4 concentrations compared to controls is not significant.
Co-Authors , stf1 ., Rodiya ., Sutisno Afief, Arief R. Ais Hamidah Aisy, Asri Rihadatul Akbar, Rai Fadiilah Akrom, Akrom Amanatin, Alfitia Dwi Andriswana, Dwi Meiria Anjastika, Luky Septiansyah Anna Pradiningsih Annisa, Fatin Maura Antonia, Vonny apriliasanti, Wahyuni Auliya, Muhammad Febri Ayuditiawati, Meita Ita Cantika, Dwi Putri Dewi, Komala Dyah Aryani Perwitasari Fatmawati, Eva Fauzia, Rizki Rahmah Haerunnisa, Tita Hakkin, Atini Sabila HARYATI, ETI Hasimun, Patonah Husni Mubarok Joharudin, Ade Karlina, Elis Karphiawati, Aldilla Shalsa Karsidin, Bambang Mahfudh , Nurkhasanah Mardhiyyah, Cut Ainul Maulida, Nur Afifah Mega Suryani, Mega Meiria A, Dwi Mundzir, Ahmad Mundzir, O Ahmad Mundzir, O. Ahmad Nafi'ah, Rahma Nafilah, Nella Nahdliyah, Vivi Afiyatun Ndang Ikbal Maulana Nopita, Juwita noviani, Adis Novianti, Sari Nuari, Ris Ayu Nur Imam Komara Nurfaizi, Deni Nurhasanah, Sarah Nurkhasanah Nurkhasanah Nurkhasanah Pandanwangi , Siti Putera, Rizky Medino Regar, Dhea Novakinanda Rustanti, Mega Ryansyah, Hardi Sabarudin, Cecep Saefullah, Indah Silviyanti Setriyadi, Dedy Siti Pandanwangi TW Siti Pandawangi TW Sodik, Jajang Japar Subagja . Subagja, Subagja Sugiarto, Anto Sugiharto, Anto Sugiharto, Yuyun Suhada, Tatik Sofiyani Suharmono, Soni Sumari Sumari Sundari, Retno T Supriatna, Cece Susanti, Nina Pratiwi Tamala, Nur Feggy Tanti Tanujaya, Jojon Titiek Suhardi Haripurnomo Kushadiwijaya Hidayati Tsai, Mei Ling TW, Siti Pandanwangi Wahyuni, Yenny Sri Widianingsih, Nining Yani, Dosi Ahmad Yuniuswoyo, Wirsad Yusniawati, Feni Zakiah, Fitri Zakiyah, Fitri Zanki, Alfriani Melia