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All Journal Indonesian Journal of Chemistry JCRS (Journal of Community Research and Service) Indonesian Journal of Biological Pharmacy Abdimas Indonesian Journal Sevanam: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Panacea Journal of Pharmaceuticals and Natural Sciences Jurnal Sains dan Kesehatan Jurnal Abdita Naturafarm Jurnal Riseta Naturafarm
Ibrahim, Arsyik
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Metabolit Sekunder dan Aktivitas Antibakteri Ekstrak Metanol Daun Kamboja Putih (Plumeria acuminata Ait) Terhadap Beberapa Bakteri Uji Farid, Riza; Fitriani, Victoria Yulita; Ibrahim, Arsyik
Jurnal Riseta Naturafarm Vol. 1 No. 1 (2024): Jurnal Riseta Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/mrvbwp06

Abstract

Kamboja (Plumeria acuminata Ait) plant is traditional medicine used as medication for ulcer and abscess. Steroid and tanin is component of chemical compound in kamboja leaves that supposed to have antibacterial activity. This study aims to determine the content of secondary metabolites and effective concentration of methanol extracts of kamboja leaves as antibacterial. Identification contains of secondary metabolites by used reagent Mayer, Dragendorf, Liebermann-Burchard, FeCl, Mg powder and HCl. Analysis of secondary metabolites characterized by the presence of sediment or froth. The antibacterial activity test carried out by agar diffusion method. Inhibition zone is analyzed by Anava and Duncan test. Secondary metabolite the compound containing steroid and tanin. The effective concentration of 40% were significantly different with a value of p = 0.00 (p<0.05) on the growth of Streptococcus mutans and Staphylococcus aureus bacteria and a concentration of 30% is very significantly different from the value of p = 0.00 (p<0.05) on the growth of Escherichia coli bacteria in vitro.
Metabolit Sekunder dan Uji Bioaktivitas Sitotoksik Ekstrak Buah Sumpit (Brucea javanica (L.) Merr) terhadap Artemia salina Leach Nur, Tajuddin; Rusman, Arman; Hikmawan, Baso Didik; Almaida, Maria; Herman; Ibrahim, Arsyik
Jurnal Riseta Naturafarm Vol. 1 No. 1 (2024): Jurnal Riseta Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/368zcy93

Abstract

Research carried out with the title of Secondary Metabolite Identification and bioactivity Fruit Extract Sumpit (Brucea javanica (L) Merr) to the shrimp larvae Artemia salina Leach. This study aims to identifying classes of secondary metabolites as well as test the bioactivity of secondary metabolites sumpit. Identifikasi fruit extracts performed to test the Chopsticks fruit extracts and fractions against reagent, while the bioactivity test was conducted using Brine Shrimp Lethality Test (BSLT). Data were analyzed using the method of Reed and Muench to get Lethality Concrentation value 50% (LC50). The results showed that the fruit extract Sumpit contain the alkaloid class of secondary metabolites, karatenoid, saponins, tannins, phenolic compounds, steroids, and terpenoids. Sumpit fruit bioactivity test results had LC50 values of the methanol extract of 3.10 ppm, n-hexane fraction of 2.09 ppm, 0.79 ppm ethyl acetate fraction and n-butanol fractions of 0.74 ppm.
Pharmacognosic Study and Determination of Marker Compounds Soursop Leaves (Annona muricata) M. Arifuddin; Faisal, Muhammad; Samsul, Erwin; Hikmawan, Baso Didik; Prabowo, Wisnu; Ahmad, Islamudin; Ibrahim, Arsyik
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 1 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/zjthbv92

Abstract

Soursop (Annona muricata) is reported to have great efficacy in traditional medicine in Indonesia so it is very vulnerable to being faked or sold as low quality. Apart from having a delicious fruit taste, Soursop leaves have also been used as an effective cancer medicine by the public and have been scientifically proven so that Soursop can be used as a phytopharmaceutical product. Therefore, it is necessary to carry out research to determine pharmacognosy parameters and marker compounds as ingredients needed to obtain the authenticity of simplicia and plant extracts. This research includes macroscopic and microscopic examination of leaves, macroscopic and microscopic examination of simplicia, fluorescence characteristics of simplicia, determining the solubility of methanol extract in various non-polar and polar solvents as well as the characteristics of marker compounds that can be used as alternatives to existing marker compounds from Soursop (Annona muricata). The research results obtained are important information as a stage for the identification and standardization of soursop leaves (Annona muricata) as a raw material for herbal medicine.
Potential and Activities of the Sunscreen Lotion Preparation of Bawang Dayak (Eleutherine americana (Aubl.) Merr. by Ethanol Extract Fraction from East Boneo Ibrahim, Arsyik; Badawi, Satriani; Rusman, Arman; Riki; Samsul, Erwin; Sulistyarini, Riski; Arifuddin, M.; Ahmad, Islamudin
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 2 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/yrb89026

Abstract

Has conducted research Potential and Activities of the Sunscreen Lotion of Bawang Dayak (Eleutherine americana (Aubl.) Merr. by ethanol extract fraction from East Borneo. The purpose of the study was to determine the potency ann activity of the sunscreen ethanol extracts fraction of Bawang Dayak in the preparation of a lotion with the parameter measuring the percent transmission erythema (% Te) and pigmentation (% Tp) in vitro in the room temperature 27oC storage and accelerated temperature 40oC. Lotion dosage formulations using ethanol extracts fraction bawang Dayak with a concentration of 0.1% and 0.2%, and positive control is a trademark preparation Bless Sunscreen Lotion SPF 15®. Stages of research include the formulation and measurement of absorbance and value %Te) and %Tp at various storage temperatures with UV-Vis spectrophotometry at λ 292.5 to 372.5 nm. The analysis of research data using a program SPSS. The results showed that ethanol extract fraction concentration in lotion preparations of bawang Dayak 0.1% and 0.2% active as a sunscreen included in the category of sunblock. The extract fraction is active as a sunscreen and in the Sunbloc category, with the best concentration as a sunscreen being 0.2%, with its sunscreen potential not being significantly different from the control Sunscreen SPF 15® at the 5% level.
Edukasi Beyond Use Date (BUD) kepada Masyarakat di Puskesmas Lempake Samarinda Samsul, Erwin; Sari, Indah Dewi; Pasaribu, Handayani; Mus, Nurul Muhlisa; Hikmawan, Baso Didik; Arifuddin, M.; Rusman, Arman; Riki, Riki; Bone, Mahfuzun; Herman, Herman; Junaidin, Junaidin; Febrina, Lizma; Ibrahim, Arsyik; Rijai, Hifdzur Rashif; Ahmad, Islamudin; Almeida, Maria; Rijai, Laode; Arifian, Hanggara
Sevanam: Jurnal Pengabdian Masyarakat Vol 5 No 1 (2026): Maret
Publisher : Universitas Hindu Negeri I Gusti Bagus Sugriwa Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25078/sevanam.v5i3.5684

Abstract

ABSTRACT There are still some people who do not understand the difference between the expiration date (Expired Date/ED) and the drug usage limit (Beyond Use Date/BUD). BUD is the time limit for drug use after compounding or after the primary packaging is opened. This activity aims to increase public knowledge, understanding, and awareness regarding the importance of paying attention to the safe limit for drug use or Beyond Use Date (BUD), so that people can use drugs wisely, safely, and responsibly. The activity implementation method includes counseling, material presentation, distribution of leaflets or brochures, and filling out pre-tests and post-tests. The number of participants who took part in this activity was 26 people. The results of the health promotion activity at the Lempake Community Health Center, Samarinda City showed that the average knowledge of participants about Beyond Use Date before providing education was 31.92%, and increased to 88.08% after being given information. Thus, it can be concluded that this activity was successful in increasing public knowledge regarding Beyond Use Date in the Lempake Community Health Center area, Samarinda City.. Key words: Beyond Use date (BUD), Expired date (ED), Lempake Health Center Samarinda City
Green Extraction of Kleinhovia hospita Saponins: Superiority of Microwave Irradiation over Maceration and the Critical Role of Solvent Polarity Hikmawan, Baso Didik; Khotimah, Khusnul; Permana, Mutia Ramadhani Rose; Ahmad, Islamudin; Febrina, Lizma; Arifuddin, Muhammad; Ibrahim, Arsyik; Salam, Supriatno
Indonesian Journal of Biological Pharmacy Vol 5, No 3 (2025): IJBP (Desember)
Publisher : Department of Biological Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijbp.v5i3.69627

Abstract

Kleinhovia hospita is a hepatoprotective plant rich in bioactive saponins, yet conventional extraction methods remain inefficient. This study aimed to optimize saponin recovery by comparing Microwave-Assisted Extraction (MAE) against conventional maceration and assessing the effect of solvent polarity. Saponins were extracted using MAE (15 minutes) and maceration (72 h) with various ethanol concentrations ranging from 0 to 96%. Total Saponin Content (TSC) was quantified colorimetrically using the vanillin-sulfuric acid method. MAE significantly outperformed maceration, attaining a two-fold increase in saponin purity (106.67 and 52.92 mg Diosgenin Equivalent (DE)/g extract, respectively) in a fraction of the time. Solvent analysis revealed a trade-off: whereas 96% ethanol yielded the highest specific purity (133.89 mg DE/g), it resulted in low mass recovery. In contrast, 50% ethanol extracted the highest Total Saponin Yield (TSY) (18.84 mg/g powder), effectively balancing matrix swelling with solubility. MAE utilizing 50% ethanol is identified as the optimal, rapid, and green strategy for the industrial production of standardized K. hospita extracts.
Co-Authors Agus Setiawaty Almaida, Maria Almeida, Maria Anggreini, Putri Ardani, Ana Fauziyyah Rizqullah Arifian, Hanggara Arifuddin, M Arifuddin, Muhammad Badawi, Satriani Baso Didik Hikmawan Bone, Mahfuzun Bulan, Adisty Sindi Chatarina Umbul Wahyuni Erwin Samsul Fadraersada, Jaka Fahrul Rozi Farah, Harra Ismi Farid, Riza Febrina, Lizma FITRIANI, VICTORIA YULITA Herman Herman Herman Irwansyah Irwansyah Islamudin Ahmad Islamudin Ahmad Junaidin, Junaidin khusnul khotimah Laode Rijai Lizma Febrina M. Arifuddin M. Arifuddin, M. Maharani, Dhea Nur Fadillah Muhammad Faisal Mus, Nurul Muhlisa Nur, Tajuddin Nurmala, Otsuka Khaera Olivia Siregar, Vita Pasaribu, Handayani Permana, Mutia Ramadhani Rose Ramadhan, M. Rahmad Rashif Rijai, Hifdzur Rezky Khairun Nisaa, Nur Ridhotulloh, Yusuf Isro Rija'i, Hifdzur Rashif Rijai, Hifdzur Rashif Rija’i, Hifdzur Rashif Riki RIKI RIKI, RIKI Rolan Rusli Rosalia, Sheilla Rusman, Arman Salam, Supriatno Sari, Indah Dewi Sinthary, Venna Sulistyarini, Riski Supriatno WISNU PRABOWO