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All Journal Indonesian Journal of Chemistry JCRS (Journal of Community Research and Service) Abdimas Indonesian Journal Jurnal Pengabdian Masyarakat Panacea Journal of Pharmaceuticals and Natural Sciences Jurnal Sains dan Kesehatan Jurnal Abdita Naturafarm Jurnal Riseta Naturafarm
Ibrahim, Arsyik
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Metabolit Sekunder dan Aktivitas Antibakteri Ekstrak Metanol Daun Kamboja Putih (Plumeria acuminata Ait) Terhadap Beberapa Bakteri Uji Farid, Riza; Fitriani, Victoria Yulita; Ibrahim, Arsyik
Jurnal Riseta Naturafarm Vol. 1 No. 1 (2024): Jurnal Riseta Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/mrvbwp06

Abstract

Kamboja (Plumeria acuminata Ait) plant is traditional medicine used as medication for ulcer and abscess. Steroid and tanin is component of chemical compound in kamboja leaves that supposed to have antibacterial activity. This study aims to determine the content of secondary metabolites and effective concentration of methanol extracts of kamboja leaves as antibacterial. Identification contains of secondary metabolites by used reagent Mayer, Dragendorf, Liebermann-Burchard, FeCl, Mg powder and HCl. Analysis of secondary metabolites characterized by the presence of sediment or froth. The antibacterial activity test carried out by agar diffusion method. Inhibition zone is analyzed by Anava and Duncan test. Secondary metabolite the compound containing steroid and tanin. The effective concentration of 40% were significantly different with a value of p = 0.00 (p<0.05) on the growth of Streptococcus mutans and Staphylococcus aureus bacteria and a concentration of 30% is very significantly different from the value of p = 0.00 (p<0.05) on the growth of Escherichia coli bacteria in vitro.
Metabolit Sekunder dan Uji Bioaktivitas Sitotoksik Ekstrak Buah Sumpit (Brucea javanica (L.) Merr) terhadap Artemia salina Leach Nur, Tajuddin; Rusman, Arman; Hikmawan, Baso Didik; Almaida, Maria; Herman; Ibrahim, Arsyik
Jurnal Riseta Naturafarm Vol. 1 No. 1 (2024): Jurnal Riseta Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/368zcy93

Abstract

Research carried out with the title of Secondary Metabolite Identification and bioactivity Fruit Extract Sumpit (Brucea javanica (L) Merr) to the shrimp larvae Artemia salina Leach. This study aims to identifying classes of secondary metabolites as well as test the bioactivity of secondary metabolites sumpit. Identifikasi fruit extracts performed to test the Chopsticks fruit extracts and fractions against reagent, while the bioactivity test was conducted using Brine Shrimp Lethality Test (BSLT). Data were analyzed using the method of Reed and Muench to get Lethality Concrentation value 50% (LC50). The results showed that the fruit extract Sumpit contain the alkaloid class of secondary metabolites, karatenoid, saponins, tannins, phenolic compounds, steroids, and terpenoids. Sumpit fruit bioactivity test results had LC50 values of the methanol extract of 3.10 ppm, n-hexane fraction of 2.09 ppm, 0.79 ppm ethyl acetate fraction and n-butanol fractions of 0.74 ppm.
Pharmacognosic Study and Determination of Marker Compounds Soursop Leaves (Annona muricata) M. Arifuddin; Faisal, Muhammad; Samsul, Erwin; Hikmawan, Baso Didik; Prabowo, Wisnu; Ahmad, Islamudin; Ibrahim, Arsyik
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 1 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/zjthbv92

Abstract

Soursop (Annona muricata) is reported to have great efficacy in traditional medicine in Indonesia so it is very vulnerable to being faked or sold as low quality. Apart from having a delicious fruit taste, Soursop leaves have also been used as an effective cancer medicine by the public and have been scientifically proven so that Soursop can be used as a phytopharmaceutical product. Therefore, it is necessary to carry out research to determine pharmacognosy parameters and marker compounds as ingredients needed to obtain the authenticity of simplicia and plant extracts. This research includes macroscopic and microscopic examination of leaves, macroscopic and microscopic examination of simplicia, fluorescence characteristics of simplicia, determining the solubility of methanol extract in various non-polar and polar solvents as well as the characteristics of marker compounds that can be used as alternatives to existing marker compounds from Soursop (Annona muricata). The research results obtained are important information as a stage for the identification and standardization of soursop leaves (Annona muricata) as a raw material for herbal medicine.
Potential and Activities of the Sunscreen Lotion Preparation of Bawang Dayak (Eleutherine americana (Aubl.) Merr. by Ethanol Extract Fraction from East Boneo Ibrahim, Arsyik; Badawi, Satriani; Rusman, Arman; Riki; Samsul, Erwin; Sulistyarini, Riski; Arifuddin, M.; Ahmad, Islamudin
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 2 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/yrb89026

Abstract

Has conducted research Potential and Activities of the Sunscreen Lotion of Bawang Dayak (Eleutherine americana (Aubl.) Merr. by ethanol extract fraction from East Borneo. The purpose of the study was to determine the potency ann activity of the sunscreen ethanol extracts fraction of Bawang Dayak in the preparation of a lotion with the parameter measuring the percent transmission erythema (% Te) and pigmentation (% Tp) in vitro in the room temperature 27oC storage and accelerated temperature 40oC. Lotion dosage formulations using ethanol extracts fraction bawang Dayak with a concentration of 0.1% and 0.2%, and positive control is a trademark preparation Bless Sunscreen Lotion SPF 15®. Stages of research include the formulation and measurement of absorbance and value %Te) and %Tp at various storage temperatures with UV-Vis spectrophotometry at λ 292.5 to 372.5 nm. The analysis of research data using a program SPSS. The results showed that ethanol extract fraction concentration in lotion preparations of bawang Dayak 0.1% and 0.2% active as a sunscreen included in the category of sunblock. The extract fraction is active as a sunscreen and in the Sunbloc category, with the best concentration as a sunscreen being 0.2%, with its sunscreen potential not being significantly different from the control Sunscreen SPF 15® at the 5% level.
Improving Elementary School Students' Knowledge About the Dangers of Intestinal Worms Through Interactive Health Education Programs: Peningkatan Kesadaran Siswa SD Tentang Bahaya Cacing Usus melalui Program Edukasi Kesehatan Interaktif Ariyanti, Syahida; Nurfitri, Nurfitri; Ibrahim, Arsyik
Jurnal Abdita Naturafarm Vol. 3 No. 1 (2026): J Abdita Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jan.v3i1.35

Abstract

Helminthiasis is a disease commonly found in tropical regions, transmitted through soil, and capable of causing intestinal tract infections that result in the loss of carbohydrates, proteins, and blood. This disease is generally associated with poor personal hygiene. The prevalence of helminthiasis in Indonesia ranges from 2.5% to 62%, with an average prevalence of 28% across 181 districts/cities in 2021 (Ministry of Health, 2017). This health promotion activity aimed to improve the knowledge and awareness of students at SD Muhammadiyah 4 Samarinda regarding the dangers and prevention of helminthiasis, as well as to provide understanding of the pharmacist’s role in community life. The methods included presentations using PowerPoint, distribution of leaflets, and administration of pre- and post-intervention questionnaires. The results showed an 8% increase in students’ knowledge about helminthiasis prevention, rising from 81% before the intervention to 89% after.
Alkaloid Profiling of Kadamba (Mitragyna speciosa Korth. Havil.) Leaves through Chromatographic Separation and UV-Vis Spectrophotometery Analysis Arifuddin, M.; Azmi, Fatur Rahman; Iswahyudi, Iswahyudi; Bone, Mahfuzun; Farrah, Harra Ismi; Arifian, Hanggara; Almeida, Maria; Rusman, Arman; Samsul, Erwin; Riki, Riki; Rija'i, Hifdzur Rashif; Hikmawan, Baso Didik; Junaidin, Junaidin; Febrina, Lizma; Rusli, Rolan; Ibrahim, Arsyik; Ahmad, Islamudin; Herman, Herman
Journal of Pharmaceuticals and Natural Sciences Vol. 2 No. 3 (2025): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jpns.v2i3.44

Abstract

Mitragyna speciosa Korth. berasal dari famili Rubiaceae yang banyak tumbuh di daratan negara-negara Asia Tenggara. Tumbuhan ini selain disebut Kratom, khususnya di daerah Kalimantan Timur dikenal juga dengan nama "Kadamba". Mitragyna speciosa Korth. belongs to the Rubiaceae family and is widely found in the mainland of Southeast Asian countries. This plant, known as Kratom, is also referred to as "Kadamba" in East Kalimantan. Kadamba has been used for generations as a traditional medicine and contains predominantly alkaloid compounds, which generally function as analgesics, antitussives, antidiarrheals, adrenergic agents, antimalarials, antibacterials, and antinociceptives. The aim of this research is to determine the isolation and identification methods for alkaloid compounds in Kadamba leaves. In this study, extraction was performed using methanol solvent, followed by fractionation using Vacuum Liquid Chromatography (VLC) and Column Chromatography (CC) with gradient eluents: 100% hexane, n-hexane : Ethyl Acetate (5:1, 1:1, 1:5), 100% Ethyl Acetate, Ethyl Acetate : Methanol (1:1, 1:5), and 100% Methanol. The compounds were then identified using Thin Layer Chromatography (TLC). The isolation process used preparative Thin Layer Chromatography (PTLC) with eluent n-hexane: ethyl acetate: 25% ammonia (6.5:3:0.5 v/v/v), and the spots were observed under UV light at 245 nm and 366 nm. The visible spots were sprayed with Dragendorff's reagent to identify the alkaloid compounds. The results showed that the UV-Vis spectrophotometric characterization of isolate B6-b had two peaks at wavelengths of 288 nm and 294 nm.
Co-Authors Agus Setiawaty Almaida, Maria Almeida, Maria Anggreini, Putri Ardani, Ana Fauziyyah Rizqullah Arifian, Hanggara Arifuddin, M Arifuddin, Muhammad Ariyanti, Syahida Azmi, Fatur Rahman Badawi, Satriani Baso Didik Hikmawan Bone, Mahfuzun Bulan, Adisty Sindi Chatarina Umbul Wahyuni Fadraersada, Jaka Fahrul Rozi Farah, Harra Ismi Farid, Riza Farrah, Harra Ismi Febrina, Lizma FITRIANI, VICTORIA YULITA Herman Herman Herman Herman Hikmawan, Baso Didik Irwansyah Irwansyah Islamudin Ahmad Islamudin Ahmad ISWAHYUDI ISWAHYUDI Junaidin, Junaidin Laode Rijai Lizma Febrina M. Arifuddin M. Arifuddin, M. Maharani, Dhea Nur Fadillah Muhammad Faisal Mus, Nurul Muhlisa Nur, Tajuddin Nurfitri Nurfitri, Nurfitri Nurmala, Otsuka Khaera Olivia Siregar, Vita Ramadhan, M. Rahmad Rashif Rijai, Hifdzur Rezky Khairun Nisaa, Nur Ridhotulloh, Yusuf Isro Rija'i, Hifdzur Rashif Rijai, Hifdzur Rashif Rija’i, Hifdzur Rashif Riki RIKI RIKI, RIKI Rolan Rusli Rosalia, Sheilla Rusman, Arman Samsul, Erwin Sinthary, Venna Sulistyarini, Riski Supriatno WISNU PRABOWO