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All Journal EKSAKTA: Journal of Sciences and Data Analysis Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences The Journal of Experimental Life Sciences (JELS) Biotropika Indonesian Green Technology Journal The Journal of Pure and Applied Chemistry Research Journal of Mathematical and Fundamental Sciences Jurnal Penelitian Pendidikan IPA (JPPIPA) JURNAL CITRA KEPERAWATAN Indonesian Journal of Chemistry Indonesian Food Science and TechnologyJournal Berdikari: Jurnal Pengabdian Masyarakat Indonesia International Journal of Community Service Learning JKPK (Jurnal Kimia dan Pendidikan Kimia) JSMARTech : Journal of Smart Bioprospecting and Technology Jurnal Pengabdian kepada Masyarakat Nusantara Journal of Applied Veterinary Science and Technology Berkala Penelitian Hayati Tri Dharma Mandiri: Diseminasi dan Hilirisasi Riset Kepada Masyarakat (Jurnal Pengabdian Kepada Masyarakat) Makara Journal of Science Pustaka: Jurnal Bahasa dan Pendidikan Bagimu Negeri : Jurnal Pengabdian Kepada Masyarakat Engagement: Jurnal Pengabdian Kepada Masyarakat DIVERSITY: Journal of Multi Science Linearity Journal of Tropical Diversity
Safitri, Anna
Brawijaya University
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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PENCEGAHAN STUNTING SEJAK USIA REMAJA DI LKSA TUNAS HARAPAN AISYIYAH PRINGSEWU Fatimah, Wahyu Dwi; Oktarini, Dwi; Sunarni, Sunarni; Safitri, Anna; Muhrimah, Siti
Bagimu Negeri Vol 8, No 1 (2024)
Publisher : Universitas Muhammadiyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52657/bagimunegeri.v8i1.2380

Abstract

Salah satu kondisi gangguan gizi kronis yang terjadi pada anak dikenal dengan stunting. Stunting perlu dicegah sejak dini, dengan upaya yang dilakukan lebih awal. Remaja menjadi salah satu target upaya pencegahan stunting, karena pada masa ini remaja memiliki kecenderungan terjadinya anemia. Jika kondisi ini tidak dicegah, maka akan berdampak pada persiapan calon ibu di masa yang akan datang. Sehingga perlu adanya penyuluhan atau pemberian informasi tentang pencegahan stunting, sebagai tujuan dari pengabdian ini. Kegiatan pengabdian ini menggunakan metode edukasi dan cek kesehatan melalui pos-pos kesehatan. Kegiatan dilakukan pada anak remaja di LKSA Tunas Harapan Aisyiyah Pringsewu yang berjumlah 15 orang. Setelah dilakukan penyuluhan didapatkan remaja memahami edukasi yang diberikan dan memiliki keinginan untuk melakukan mencegahan stunting dari diri sendiri.
Evaluation of Bioactive Compounds, Release Profiles, and Toxicity Test from Microcapsules Containing R. tuberosa L. Extracts Utilizing Gum Arabic Almayda, Nabila; Roosdiana, Anna; MASRURI, Masruri; Safitri, Anna
The Journal of Pure and Applied Chemistry Research Vol. 13 No. 1 (2024): Edition January-April 2024
Publisher : Chemistry Department, The University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jpacr.2024.013.01.3336

Abstract

This study is essential to analyze the toxicity and release of bioactive compounds in R. tuberosa L. extract microcapsules coated with gum Arabic and to provide information on the use of microcapsules as a drug delivery system with controlled release of active ingredients. Investigations focused on the effect of pH and timing on discharge kinetics, as well as toxicity evaluation. The release of active ingredients from microcapsules was carried out in medium variations, namely pH 2.2 and pH 7.4, with release durations of 30, 60-, 90-, 120-, and 150-min. Bioactive compounds were released by 59.23% at pH 2.2 and 58.21% at pH 7.4 within 150 min. The BSLT (brine shrimp lethal toxicity) assay was used using brine shrimp larvae (Artemia salina L.), resulting in a non-toxic classification as evidenced by an LC50 value of 5729 μg/mL. Microcapsules in optimum conditions were then characterized using FTIR (Fourier-Transform Infrared) and SEM (scanning electron microscopy) instruments. The FTIR analysis showed variations in functional groups in R. tuberosa L. extracts, gum Arabic, and microcapsules. Furthermore, the SEM examination highlighted the morphology of microcapsules that were mostly spherical.
Phytochemical Screening and Antibacterial Activity of Ethanolic Extracts from Delonix regia Against Laboratory Strains of Diarrheal Bacteria Senge, Yeyen Susana; Mustafa, Irfan; Safitri, Anna
JKPK (Jurnal Kimia dan Pendidikan Kimia) Vol 9, No 1 (2024): JKPK (Jurnal Kimia dan Pendidikan Kimia)
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jkpk.v9i1.85375

Abstract

The present study evaluates the antibacterial efficacy of ethanolic extracts from Delonix regia leaves against diarrhea-inducing bacteria Escherichia coli and Salmonella typhimurium. Preliminary phytochemical screening revealed that D. regia leaves comprise flavonoids, alkaloids, saponins, tannins, phenolics, and terpenoids. Fourier Transform Infrared Spectroscopy (FTIR) analysis identified various functional groups in the D. regia leaf extract, including O-H, C-H, C=O, C=C, C-C, C-O, and C-O-C. Liquid Chromatography-Mass Spectrometry/Mass Spectrometry (LC-MS/MS) analysis further confirmed the presence of 16 distinct compounds comprising amino acids, alkaloids, phenolics, flavonoids, terpenoids, anthraquinones, n-acyl pyrrolidines, and fatty acids. The disc diffusion method (Kirby-Bauer) was employed for the antibacterial tests. The extracts of D. regia leaves at concentrations of 25%, 50%, 75%, and 100% generated inhibition zones measuring 5.26 mm, 6.37 mm, 7.27 mm, and 10.18 mm against E. coli, and 5.05 mm, 7.01 mm, 8.77 mm, and 10.04 mm against S. typhimurium, respectively. The commercial antibiotic ciprofloxacin (a positive control) produced inhibition zones of 30.02 mm for E. coli and 28 mm for S. typhimurium. The negative control, consisting of 10% ethanol, showed no inhibitory effect on bacterial growth. These findings indicate that the ethanolic extract of D. regia leaves possesses antibacterial properties against E. coli and S. typhimurium. It is likely that secondary metabolite compounds, such as flavonoids and phenolics, contribute significantly to the observed antibacterial activity
Alginate-Based Microbeads from Encapsulated Cosmos Caudatus K. Extracts: In Vitro Release Profiles Fadlila, Safina Samara Nur; Puspita, Oktavia Eka; Ningsih, Zubaidah; Safitri, Anna
EKSAKTA: Journal of Sciences and Data Analysis VOLUME 5, ISSUE 2, October 2024
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/EKSAKTA.vol5.iss2.art4

Abstract

This study aims to investigate the microencapsulation of C. caudatus K. leaves extract under optimal conditions, focusing on its potential as a therapeutic option for type 2 diabetes. In order to determine the inhibitory effect on the α-amylase enzyme, which plays a crucial role in glucose metabolism, biological activity assays were performed. The procedure of effectively encapsulating the substance was achieved at a pH level of 6 using sodium alginate at a concentration of 2% (w/v), resulting in a 77.2% percentage of encapsulation. The experiment involving the inhibition of α-amylase exhibited an IC50 value of 69.44 ± 0.924 μg/mL, demonstrating the significant biological activity of the microcapsules. The bioactive substances encapsulated in the microcapsules were released during intervals 30-120 min, at pH conditions of 2.2 and 7.4. The release of bioactive substances was only 2.32 % after 120 minutes at a pH of 2.2, whereas it increased to 64.54 % at a pH of 7.4. This discovery indicates that the microcapsules contain the capability to be utilized for the regulated delivery of drugs. The findings of this research demonstrate the potential to develop herbal medicines with therapeutic properties through microencapsulation, providing an excellent opportunity for managing type 2 diabetes.
Microencapsulation by Spray drying of Cosmos caudatus Kunth. Extracts Using Gum Arabic: Influencing Factors and Controlled Release Zahara, Izaz Aqeiluz; Sutrisno, Sutrisno; Ulfa, Siti Mariyah; Safitri, Anna
Indonesian Food Science and Technology Journal Vol. 8 No. 1 (2024): Volume 8 Number 1, December 2024 |IFSTJ|
Publisher : Department of Technology of Agricultural product (THP) Jambi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/ifstj.v8i1.32818

Abstract

Advanced drug delivery systems are required due to the increasing advancement in science and technology, with a common example being microencapsulation. This system is affected by the manufacturing conditions and slow release of bioactive compounds inside microcapsule. In general, phytochemicals in the edible plant, Cosmos caudatus Kunth, specifically flavonoids, offer several health benefits but are susceptible to degradation which reduces biological activities. Therefore, this study aimed to encapsulate extract using spray drying method, which can be used as wall material in Gum Arabic. Microencapsulated product was also tested for biological activities. The effect of microcapsule production was investigated, including the concentration of wall material and the stirring speed. Furthermore, the optimal conditions of microcapsule were selected based on the highest encapsulation efficiency. The results showed that a concentration of 4% (w/v) Gum Arabic and a stirring speed of 800 rpm were the optimal conditions, leading to a percentage release of 71.87%. Microcapsule under these conditions produced an IC50 value of 55.09 ± 0.57 ug/mL as an inhibitor of alpha-amylase enzyme. The characterization by scanning electron microscope (SEM) showed spherical forms with a mean diameter of 152.00 um. The bioactive substance in microcapsule was released at pH 2.2 and pH 7.4 for 30 to 120 min, with a percentage release of 38.05% and 95.14%, respectively. In conclusion, this study confirmed that microencapsulation played a crucial role in the development of plant extract with retained biological functions.
Freeze-Drying Microencapsulation of Ruellia tuberosa L. Extracts: A Comparative Study Using Different Polymers as Encapsulants Gunawan, Firza Rajasa; Ulfa, Siti Mariyah; Safitri, Anna
Indonesian Journal of Chemistry Vol 25, No 1 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.95246

Abstract

Ruellia tuberosa L. leaf and root extracts have been investigated for their biological activity and potential health advantages, including their antidiabetic, antioxidant, and antidiuretic qualities. This research evaluates the freeze-drying microencapsulation of R. tuberosa L. extracts using gum Arabic, maltodextrin, and their combination as coating materials. The resulting microcapsules were tested for encapsulation efficiency, biological activity, and controlled release. Characterization techniques included scanning electron microscopy (SEM), Fourier-transform infrared (FTIR) spectroscopy, and particle size analysis (PSA). The choice of encapsulant significantly influenced encapsulation efficiency, morphology, and biological activity. Microcapsules using a combination of gum Arabic and maltodextrin exhibited more spherical shapes and smaller particle sizes than those using either material alone. Alpha-amylase inhibition tests showed that microcapsules effectively inhibit the enzyme, with the coating combination performing best, followed by gum Arabic and then maltodextrin. All microcapsules exhibit moderate antioxidant activity, again in the same order. The active compound release was greater at pH 7.4 compared to pH 2.2 from 0 to 120 min. Therefore, freeze-drying microencapsulation with biodegradable polymers is a viable method for delivering the health benefits of R. tuberosa L. extracts, yielding a convenient powder form suitable for drug delivery systems.
Preventive Effect of Antioxidant From Purple Rosella Yoghurt on Duodenum and Colon Histopathology of Rattus norvegicus Exposed to Rhodamine B And Saccharin Haskito, Ajeng Erika Prihastuti; Nariswari, Bintari; Safitri, Anna; Noviatri, Aldila; Untari, Handayu; Sari, Citra
The Journal of Experimental Life Science Vol. 14 No. 1 (2024)
Publisher : Graduate School, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jels.2024.014.01.04

Abstract

Rodhamine B and Saccharin are often misused by food producers as food additive, which, if their use is not monitored, can produce free radicals that cause oxidative stress conditions in the body, leading to dangerous damage to the body. The addition of purple rosella in yoghurt can increase the functional value of the yoghurt, namely increasing the antioxidant content. The purpose of this study was to determine the benefits of giving purple rosella yoghurt in preventing damage to the duodenum and colon of (Rattus norvegicus) caused by Rodhamine B and Saccharin. This study used Completely Randomized Design (CRD) with 28 male R. novergicus, Wistar strain in aged 8-12 weeks. Group K was not given any treatment; R was given Rodhamine B, S was given Saccharin, KRS was given Rodhamine B and Saccharin, YR was given Rodhamine B and yoghurt, YS was given Saccharin and yogurt, YRS was given Rodhamine B, Saccharin and yogurt. The dose of Rodhamine B was 22.5 mg.kg-1, Saccharin was 157.77 mg.kg-1, and the volume of yoghurt was 1 mL.head-1. They were administered orally with a gastric tube for 14 days. The concentration of purple rosella extract added to yoghurt was 15% (v/v). Parameters were observed in histopathology of the duodenum and colon with the scoring method. Data analysis was done with the Kruskal-Wallis test followed by the Mann-Whitney test. The KRS group showed the heaviest damage, namely necrosis, villi erosion, and inflammatory cell infiltration of >75% of the total visual field in the duodenum and colon. The YR, YS, and YRS groups showed significant changes compared to the R, S, and KRS groups, namely necrosis, villous erosion, and inflammatory cell infiltration, which appeared to be 25-50% of the total visual field. However, this did not match the condition of group K, which appeared to be <25% of the total visual field. The provision of purple rosella yoghurt can prevent 50% damage to the duodenum and colon of Rattus novergicus due to Rodhamine B and Saccharin. Keywords: colon, duodenum, Rodhamine B, Saccharin, yoghurt.
Sosialisasi Metode Uji Cepat Kandungan Zat Berbahaya pada Makanan Jajanan di Sekitar Sekolah SDI Surya Buana Malang Safitri, Anna; Prasetyawan, Sasangka; Mahdi, Chanif
TRI DHARMA MANDIRI: Dissemination and Downstreaming of Research to the Community (Journal of Community Engagement) Vol 1 No 1 (2021)
Publisher : SMONAGENES Research Center, Univeritas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jtridharma.2021.001.01.1

Abstract

Makanan yang beredar di masyarakat saat ini, khususnya di sekolah dasar, lebih banyak berupa makanan instan yang sarat dengan bahan aditif seperti bahan pengawet, perasa, pewarna, dan pemanis, serta kadar nutrisi yang kurang untuk memenuhi kebutuhan harian anak. Tujuan kegiatan pengabdian kepada masyarakat ini adalah untuk memperkenalkan informasi dan pengetahuan tentang bahaya mengkonsumsi makanan jajanan di sekitar sekolah yang mengandung zat berbahaya seperti formalin, boraks, dan zat warna sintetis. Kegiatan ini juga bertujuan memperkenalkan metode uji makanan jajanan di sekitar sekolah yang mengandung zat berbahaya seperti formalin, boraks, dan zat warna sintetis. Peserta kegiatan adalah guru-guru SDI Surya Buana, Malang. Kegiatan dilakukan melalui tiga tahapan yaitu: 1. Pembuatan modul; 2. Penyuluhan; 3. Pelatihan serta uji bersama kandungan bahan pengawet dan pewarna berbahaya. Evaluasi dilakukan dalam 2 tahap, yaitu evaluasi, yaitu evaluasi pada saat pelaksanaan kegiatan dan evaluasi pasca pelaksanaan Kegiatan pengabdian masyarakat dilaksanakan pada tanggal 12 Agustus 2020, di SDI Surya Buana. Kegiatan dihadiri oleh Kepala SDI Surya Buana dan oleh 40 orang guru-guru. Pada kegiatan tersebut dilakukan presentasi tentang bahaya makanan jajanan yang mengandung boraks, formalin, dan zat warna tekstil. Kegiatan lainnya adalah peragaan tes uji cepat makanan jajanan menggunakan tes kit untuk uji formalin, boraks, dan zat warna. Pada awal dan di akhir acara, dibagikan kuesioner untuk evaluasi kegiatan. Hasil evaluasi menunjukkan bahwa 100% responden puas setelah mengikuti kegiatan ini. Dari kegiatan ini dapat disimpulkan bahwa pengetahuan tentang bahaya zat pengawet dan pewarna buatan sangat dibutuhkan bagi warga sekolah. Selain itu, warga sekolah perlu mengetahui tentang uji cepat zat pengawet dan pewarna buatan pada makanan jajanan di sekolah.
Empowerment of Farmers and Residents in Silage, Concentrate and Complete Feed Processing Technology Huda, Asri Nurul; Wardhani, Sri; Safitri, Anna; Dinira, Layta; Gatrananda, Sayyid Izzudin; Arief, Miftahudin
International Journal of Community Service Learning Vol. 9 No. 2 (2025): May
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/ijcsl.v9i2.84769

Abstract

Low knowledge and skills of farmers and residents in processing animal feed efficiently and sustainably. Although the potential for local raw materials is quite abundant, many farmers still rely on conventional methods that are less effective, which has an impact on the quality and availability of animal feed, especially in the lean season. Lack of access to appropriate technology and ongoing assistance are also major obstacles to increasing the productivity of the community livestock sector. The purpose of this study was to identify and formulate effective empowerment strategies for farmers and residents in developing and applying silage, concentrate, and complete feed processing technology. The type of research used is participatory action research (PAR) combined with field experimental research. The methods used include social approaches, training, and intensive assistance to target groups. The population in this study were farmers and residents involved in livestock activities, especially ruminant livestock. Data analysis is a qualitative analysis carried out for data from interviews, observations, and documentation using thematic analysis techniques or the Miles & Huberman model. The results of the activity showed an increase in farmers' skills in processing feed independently. The implications of this activity are increased livestock productivity, feed cost efficiency, and optimal utilization of local resources while reducing dependence on commercial feed.
Studi Literature Review Terkait Gaya Pimpinan Berkomunikasi Di Dalam Organisasi Anna Safitri
DIVERSITY: Journal of Multi Science Linearity Vol. 1 No. 1 (2023): DIVERSITY: Journal of Multi Science Linearity, October 2023
Publisher : ASIAN PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58738/diversity.v1i1.457

Abstract

Penelitian ini bertujuan untuk menyelidiki pengaruh gaya kepemimpinan dalam komunikasi terhadap kinerja organisasi dalam perusahaan. Gaya kepemimpinan yang dipertimbangkan dalam penelitian ini melibatkan komunikasi berdasarkan pendekatan yang demokratis, otoriter, dan transformatif. Metodologi penelitian melibatkan survei karyawan, wawancara dengan manajer senior, dan analisis data kinerja organisasi. Hasil penelitian menunjukkan bahwa gaya kepemimpinan yang berfokus pada komunikasi demokratis dan transformatif secara signifikan meningkatkan kinerja organisasi. Manajer yang menerapkan pendekatan komunikasi terbuka dan memberdayakan anggota tim cenderung mencapai hasil yang lebih baik. Selain itu, komunikasi yang memotivasi, menginspirasi, dan mendorong inovasi juga berkontribusi positif terhadap kinerja organisasi.
Co-Authors Ainun Sajidah Ajeng Erika Prihastuti Haskito Akhmad Sabarudin Aldila Noviatri Almas Dwi Khairana Almayda, Nabila Anna Roosdiana Anna Roosdiana Anna Roosdiana Anna Roosdiana Anna Roosdiana Annisa, Choirin Arie Srihardyastutie Arief, Miftahudin Ary Mustofa Ahmad Asri Nurul Huda Aulanni'am Aulanni'am Aulanni'am, Aulanni'am Aulanni`am Aulanni`am Avander Alexander Nuban Aviva Levina Aviva Levina Budi Kamulyan Cairns, James Robert Ketudat Chanif Mahdi Chanif Mahdi Citra Sari Devi Ramadani Dewi Ratih Tirto Sari Dian Siswanto Dwi Putri Woro Pamungkas Dyah Kinasih Wuragil Dzakiyyah Salmaa Eko Suyanto Ellya Indahyanti Ellysia Hitdatania Ernanin Dyah Wijayanti Eva Nur Laili Octaviana Fadlila, Safina Samara Nur Fairus Suryani Munir fatchiyah . Fatchiyah Fatchiyah Fatchiyah Fatchiyah Fatchiyah Fatchiyah Fatchiyah Fatchiyah Fatchiyah Fatchiyah Fatimah, Wahyu Dwi Febrianti, Wiwin Dwi Firza Rajasa Gunawan Gatrananda, Sayyid Izzudin Gunawan, Firza Rajasa Handayu Untari Haskito, Ajeng Erika Prihastuti Hilman Nurmahdi Irfan Mustafa Irfan Mustafa James Robert Ketudat Cairns Lay, Peter A. Layta Dinira Levina, Aviva Lidwina Faraline Triprisila Lidwina Faraline Triprisila Masruri Masruri Muh Fikry Baharuddin Muhammad Fikri Nur Muhrimah, Siti Nariswari, Bintari nasrullah wilutono Nia Kurnianingsih Nia Kurniawan Ningsih, Zubaidah Novi Kurnianingsih Noviatri, Aldila Oktarini, Dwi Oktavia Eka Puspita, Oktavia Eka Peter A Lay Peter A Lay Purnamasari, Citra Putri, Radwa Fathin H Rahmaniah, Galuh Rensani Taloin Rista Nikmatu Rohmah Saidun Fiddaroini Saniyawati, Fang You Dwi Ayu Shalu Sari, Dewi Ratih Tirto Sasangka Prasetyawan Sasangka Prasetyawan Sasangka Prasetyawan Savira Ayu Damayanti Senge, Yeyen Susana Siti Mariyah Ulfa Sovia Rosalin Sri Wardhani Suci Amaliyah Sukardi, Ernawati Sunarni Sunarni Sutrisno Sutrisno Sutrisno, Sutrisno Tri Wahyu Nugroho Ulfa Andayani Ulfa Andayani Untari, Handayu Wasino Wasino Wibi Riawan Yenny Kornitasari Yoravika Dwiwibangga Yufani, Rofika An Yusrina, Nur Zahara, Izaz Aqeiluz