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Identifikasi Kulit Batang Kalangkala (Litsea Angulata Bi) Secara Makroskopik, Mikroskopik, Dan Skrining Fitokimia Fitriyanti Fitriyanti; Syamratul Qalbiyah; Putri Indah Sayakti
Parapemikir : Jurnal Ilmiah Farmasi Vol 9, No 2 (2020): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v9i2.1832

Abstract

Kalangkala (Litsea angulata BI) merupakan salah satu spesies dari genus Litsea dan tergolong dalam keluarga Lauraceae. Sebagian masyarakat Kalimantan Selatan telah menggunakan tumbuhan Kalangkala dalam beragam pengobatan tradisional, seperti bagian kulit batangnya yang secara empiris berkhasiat untuk anti iritan. Penelitian ini bertujuan untuk memberikan data ilmiah mengenai gambaran farmakognostik secara kualitatif dengan beberapa tahapan pemeriksaan organoleptik, makroskopik, mikroskopik, ekstraksi, dan skrining fitokimia. Pada pemeriksaan organoleptik kulit batang Kalangkala segar yaitu berwarna hijau, terasa agak pahit, dan bau khas lemah. Sementara serbuk simplisianya berwarna cokelat muda, rasa pahit agak kelat, dan berbau khas agak menyengat. Hasil pemeriksaan makroskopik kulit batang Kalangkala berbentuk tipis dan lunak, ketebalannya sekitar ± 3 mm, tekstur permukaan luar kulit batang Kalangkala memiliki tipe halus namun agak kasap dan bagian permukaan dalam teraba licin juga berlendir. Pada pemeriksaan mikroskopik terdapat epidermis, vakuola, kloroplas, sel batu, hablur kalsium oksalat, serat lumen, dan jaringan gabus. Ekstrak diperoleh dari maserasi simplisia menggunakan pelarut etanol 70%. Hasil skrining fitokimia menunjukkan bahwa serbuk simplisia dan ekstrak kental kulit batang Kalangkala mengandung metabolit sekunder berupa alkaloid, flavonoid, tanin, dan saponin.
Pendampingan Peningkatan Kualitas Produk Simplisia dan Teh Celup Bawang Dayak Melalui Pengurusan PIRT di KWT Sri Rejeki Rahmi Muthia; Aristha Novyra Putri; Liana Fitriani Hasymi; Fitriyanti Fitriyanti; Rahmayanti Fitriah
Jurnal Mandala Pengabdian Masyarakat Vol. 4 No. 1 (2023): Jurnal Mandala Pengabdian Masyarakat
Publisher : Progran Studi Farmasi STIKES Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpm.v4i1.172

Abstract

KWT Sri Rejeki merupakan salah satu kelompok wanita yang membudidayakan sayuran dan tanaman yang ternyata juga bisa dimanfaatkan sebagai tanaman obat, salah satunya yaitu bawang dayak. Berdasarkan hasil pengabdian masyarakat sebelumnya tahun 2022 di KWT Sri Rejeki, produk hasil pendampingan tahun lalu telah dapat diperdagangkan secara offline maupun online namun nilai daya jualnya masih belum maksimal. Keterbatasan dan permasalahannya adalah belum dimilikinya izin edar baik untuk produk olahan simplisia maupun teh celupan bawang dayak sehingga pemasarannya sangat terbatas. Hal ini menunjukkan perlu pengembangan produk dengan pendampingan dalam pengajuan izin edar produk sehingga diharapkan juga dapat meningkatkan pemasaran produk. Tujuan pengabdian masyarakat untuk meningkatkan kualitas produk melalui pendampingan pengurusan PIRT produk simplisia dan teh celupan bawang Dayak. Metode yang dilakukan yaitu pengurusan perizinan ke UPT BPP Liang Anggang, pemberian alat penunjang pembuatan produk berupa oven pengering, pendampingan penyuluhan dari dinas Kesehatan banjarbaru terkait pengurusan izin edar PIRT, pendampingan desain kemasan sediaan, serta pengurusan izin PIRT. Pada kegiatan penyuluhan dihadiri sebanyak 30 orang. Hasil kegiatan berupa peningkatan teknologi menggunakan oven pengering pada proses pengeringan produk sehinga meningkatkan kualitas produk, Selain itu anggota KWT Sri Rejeki  lebih memahami alur perizinan dengan baik setelah disampaikan oleh dua narasumber langsung dari dinas Kesehatan banjarbaru. Hasil lainnya berupa produk dengan desain kemasan yang kekinian dan inovatif ditunjang dengan izin PIRT untuk  produk simplisia bawang Dayak dan teh celupan bawang Dayak.
Uji Aktivitas Antibakteri Ekstrak Etanol 70%, Etanol 96%, dan Metanol Daun Kelakai Merah (Stenochlaena palustris (Burm.F) Bedd) terhadap Bakteri Cutibacterium acne Fitri Yanti; Malik Yustika; Setyo Yogi; Azwarina Nuke; Rusida Esty Restiana; Vebruati Vebruati; Hidayati Rahmi
Journal Borneo Vol 3 No 3 (2023): Volume 3 Issue 3 tahun 2023
Publisher : Politeknik Kaltara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57174/j.born.v3i3.103

Abstract

Acne is an inflammation or infection of the pilosebaceous tract with the bacterium Cutibacterium acne. Lalakai or kelakai plant (S.palustris (Burm.F) Bedd) includes plants that have antibacterial activity. This study aimed to determine the yield and phytochemical compound contained in extracts of 70% ethanol, 96% ethanol, and methanol of the leaves of the (S.palustris Burm.F) Bedd) against Cutibacterium acne bacteria. The method of antibacterial activity was carried out using the good diffusion method. Tests with 6 groups of extract concentrations, namely 100%, 75%, 50%; 37.5%, 25%; and 12.5%. The phytochemical compounds test identified alkaloids, flavonoids, tannins, steroids/triterpenoids, and saponins. The highest extract yield was from 70% ethanol extract of 6.3559%. The results of the phytochemical compound showed that the 70% ethanol, 96% ethanol, and methanol extracts of the leaves Kelakai (S.palustris (Burm.F) Bedd) positively contained alkaloids, flavonoids, tannins, steroids, and saponins. The best antibacterial test came from the methanol extract (concentration of 100%) was able to inhibit C. acne with 14.475 mm (an inhibition zone diameter) which was included in the strong category.
Antibacterial Activity Test of Ethanol Extract Pineapple (Ananas comosus (L.) Merr.) Peel against Growth of Propionibacterium acnes Fitriyanti Fitriyanti; Muhammad Nur Rahman Hendrawan; Karunita Ika Astuti
Borneo Journal of Pharmacy Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v2i2.928

Abstract

Pineapple peel (Ananas comosus (L.) Merr.) is waste from the pineapple fruit. The purpose of this study was to determine the content of pineapple peel extract and to antibacterial activity in various concentrations effective in inhibiting the growth of Propionibacterium acnes. The pineapple peel extract is made by using the extraction method in the form of maceration. The method used in the inhibitory test using the three replication samples in each treatment group. The sample consisted of 10 treatment groups ie pineapple peel extract concentration 12.5%, 25%, 37.5%, 50%, 62.5%, 75%, 87.5%, and 100%, as well as positive and negative control. The results obtained from pineapple peel screening contain flavonoid and saponin compounds. The data analysis shows that pineapple peel extract concentrations of 50%, 62.5%, 75%, 87.5%, and 100% had inhibitory zones with the medium-strong category while clindamycin as the control has a strong inhibition zone. The conclusion of this research proves that pineapple peel extract has antibacterial power to P. acnes with effective concentration is 100% with the strong category.
Antioxidant Activity of Ethanolic Extract from Tandui Leaves (Mangifera rufocostata Kosterm.) by DPPH Radical Scavenging Method Revita Saputri; Tia Mariati Risma Melati; Fitriyanti Fitriyanti
Borneo Journal of Pharmacy Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v2i2.1070

Abstract

Tandui (Mangifera rufocostata Kosterm.) is a typical plant from South Kalimantan which belongs to the genus of Mangifera. Several species of Mangifera are known to have antioxidant activity. This study aimed to determine the antioxidant activity of ethanol extract of Tandui leaves. Tandui leaves that were obtained from the maceration method used 70% ethanol. Antioxidant activity was conducted quantitative using the DPPH (2,2-diphenyl-1-picrylhydrazil) method. The result of the antioxidant activity of Ethanol extract of Tandui leaves quantitatively obtained IC50 value was 60.7042 µg/mL. The ethanol extract of Tandui leaves has strong antioxidant activity
Pharmacognostic Study of Sangkareho Root (Callicarpa longifolia Lam.) from Pelaihari, South Kalimantan Fitriyanti Fitriyanti; Yusmalina Yusmalina; Rahmi Muthia
Borneo Journal of Pharmacy Vol. 3 No. 2 (2020): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3i2.1267

Abstract

Sangkareho (Callicarpa longifolia Lam.) is used traditionally by one of Kalimantan's indigenous tribes, the Dayak Tunjung tribe as a medicine for colds and inflammation, where the plant parts used are the roots. Considering its very potential prospects, research aimed at providing a scientific basis for plant pharmacognostic data needs to be carried out with qualitative methods. The qualitative examination is done by several methods including test identification of organoleptic, macroscopic, microscopic, and chemical compounds. Organoleptic test results showed that the roots have a light brown color, bitter and slightly spicy, and a rather pungent odor. Microscopic test results showed sangkareho root has a length of ± 90 cm; width of ± 1 cm; and for the form of a spear with a ride root system. Microscopic observations are found in the form of epidermal cells, exodermis, cortex, endodermis, bearing files, calcium oxalate crystals, and stone cells. The identification of chemical compounds showed positive results against alkaloids, flavonoids, saponins, and triterpenoids. The thin-layer chromatography profile shows four separate stains with eluent ethyl acetate : methanol : water in a ratio of 8 : 2 : 1, respectively.
Uji Aktivitas Antibakteri Ekstrak Metanol Daun Ramania (Bouea. macrophylla Griffith) Terhadap Bakteri Escherichia coli hairunnisa nisa; Fitriyanti Fitriyanti; Putri Kartika Sari
BORNEO JOURNAL OF PHARMASCIENTECH Vol 7 No 2 (2023): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v7i2.463

Abstract

Ramania (B. macrophylla Griffith) can beused as an antibacterial in the gastrointestinal tractOne of the bacteria in the digestive tract is Escherichia coli. The purpose of this study was to determine the group of compounds contained in ramania leaf methanol extract (B. macrophylla Griffith) and the activity of ramania leaf methanol extract (B. macrophylla Griffith) in inhibiting the growth of E. coli bacteria. Using the maceration method with methanol solvent and extract amendment of 8.6019%. Ramania leaf methanol extract (B. macrophylla Griffith) contains secondary metabolite compounds namely alkaloids, flavonoids, saponins, tannins, and steroids. Antibacterial activity test was carried out by the welling method with a concentration of methanol extract of ramania leaves (B. macrophylla Griffith) which is 1,024 mg / ml; 2,048 mg/ml; 4,096 mg/ml; 8.192 mg/ml; 16,384 mg/ml; 32,760 mg/ml; positive control of ciprofloxacin 5μg/disk, and negative control of Na-CMC 0.5%. The results of the antibacterial activity test of ramania leaf methanol extract (B. macrophylla Griffith) showed that the concentration of 2.048 mg / ml included the inhibition zone of the weak category, namely 3.33 mm;, while the concentration of 32,760 mg / ml included the moderate inhibition zone, namely mm; 8.48 mm and the positive control of ciprofloxacin 5μg / disk was included in the category of very strong inhibition zone, namely 22.8 mm. Based on the spss results using the Man-Whitney test the positive control and control had no difference due to the sig value (<0.05). It can be concluded that ramania leaf methanol extract (B. macrophylla Griffith) has antibacterial activity against E. coli bacteria and has secondary metabolite compounds found in ramania leaves (B. macrophylla Griffith) are Alkaloids, Flavonoids, Tannins, Saponins and Steroids.
Uji Aktivitas Antibakteri “Ekstrak Metanol Daun Sungkai (Peronema canescens Jack) Terhadap Bakteri Propionibacterium acnes. Shelin Shelin; Fitriyanti Fitriyanti; Muhammad Saufi
BORNEO JOURNAL OF PHARMASCIENTECH Vol 7 No 2 (2023): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v7i2.489

Abstract

The Sungkai plant (P. canescens Jack) is known to have medicinal properties in the traditional treatment of skin diseases. The aim of this research is to identify groups of phytochemical compounds contained in the methanol extract from Sungkai leaves, as well as evaluate the ability of the methanol extract to inhibit the growth of P. acnes bacteria. In the first stage, phytochemical screening was carried out from the methanol extract of Sungkai leaves. The results of this screening show that the methanol extract of Sungkai leaves contains alkaloids, flavonoids, phenols, triterpenoids and tannins. In the antibacterial activity test, the diffusion method with the well technique was used at extract concentrations of 1%, 5%, 10%, 15% and 20%. As a comparison, the positive control used clindamycin with a concentration of 2 µg/disk, while the negative control used Na-CMC with a concentration of 0.5%. The results of the antibacterial activity test showed that at a concentration of 1%, the methanol extract of Sungkai leaves had an inhibition zone with moderate intensity. However, at a concentration of 20% as well as in the positive control clindamycin with a concentration of 2 µg/disc, there was a stronger zone of inhibition. Thus, these findings indicate that methanol extract from Sungkai leaves has the potential to inhibit the growth of P. acnes, which is often associated with skin problems. The phytochemical compounds contained in this extract can be the basis for potential development in natural-based skin
Uji Aktivitas Antibakteri Ekstrak Etanol 70% Daun Ginseng Jawa (Talinum paniculatum (Jacq.) Gaertn) Terhadap Bakteri Shigella dysenteriae Riwanda Oktaviani; Fitriyanti Fitriyanti; Putri Kartika Sari
BORNEO JOURNAL OF PHARMASCIENTECH Vol 8 No 1 (2024): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v8i1.502

Abstract

Shigellosis is a digestive tract infection that can be caused by S dysenteriae bacteria. Javanese ginseng (T. paniculatum (Jacq.) Gaertner) is a plant known to have antibacterial potential. This study aims to determine the content of the class of compounds contained in the 76% ethanol extract of Javanese ginseng leaves and to observe the antibacterial activity of the 70% ethanol extract of Javanese ginseng leaves against S. dysenteriae based on the diameter of the inhibition zone. Antibacterial testing using the disc diffusion method with six variations of extract concentrations including 5%, 10%, 20%, 40%, 60% and 80% for positive and negative controls used Azithromycin 15µg/disk and 0.5% Na-CMC. Identification of the content of secondary metabolites was carried out on alkaloids, phenols, flavonoids, quinones, saponins, steroids/triterpenoids and tannins. The results of the screening test for 70% ethanol extract of Javanese ginseng leaves contained flavonoids, phenols, saponins, steroids and tannins. Antibacterial testing at the smallest concentration, namely 5% of the inhibition zone, is considered weak with an average inhibition diameter of 4.01 mm and at the largest concentration, namely 10%, the inhibition zone is considered strong with an average inhibition zone diameter of 11.26 mm.
PENGARUH METODE EKSTRAKSI TERHADAP AKTIVITAS ANTIBAKTERI DAUN RAMANIA (Bouea macrophylla Griffith) TERHADAP Staphylococcus aureus Fitriyanti; Syifa; Ahmad; Revita Saputri; Rahmi Muthia
Pharmacoscript Vol. 7 No. 1 (2024): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v7i1.1462

Abstract

Ekstrak metanol dari daun Ramania (Bouea macrophylla Griffith) telah teruji dengan dosis kecil memiliki efek antibakteri terhadap bakteri Staphylococcus aureus, namun belum pernah dilakukan pengujian pada dosis yang lebih tinggi dan membandingkan pada metode ekstraksi yang berbeda seperti maserasi dan soxhletasi. Pada penelitian bermaksud untuk mengetahui golongan senyawa yang terdapat pada ekstrak metanol dari daun ramania dengan metode yang berbeda dan untuk mengetahui pengaruh peningkatan konsentrasi ekstrak terhadap penghambatan bakteri S.aureus dengan penyarian secara maserasi dan soxhletasi. Uji antibakteri dilakukan menggunakan metode difusi sumuran. Penapisan fitokimia terhadap ektrak metanol daun remania menunjukkan keberadaan senyawa yaitu mengandung senyawa saponin, flavonoid, fenol, tanin, steroid. Hasil ují antibakteri terhadap ekstrak daun ramania yang diperoleh dengan metode maserasi lebih baik dibandingkan dengan ekstrak yang diperoleh dengan metode Soxlet, yaitu pada konsentrasi 50, 40, 30, 20 dan 10%, memberikan zona hambat berturut-turut sebesar 19,28;13,28; 12,93; 12,25; dan 10,98 mm, dengan kategori kuat. Sedangkan hasil pada pengujian dengan esktraksi menggunakan alat soxhlet pada konsentrasi 50, 40, 30, 20 dan 10%, memberikan zona hambat berturut-turut sebesar 10,7; 10,3; 8,9; 8,6; dan  8,3 mm dengan kategori sedang sampai kuat.
Co-Authors Abdurrazaq Abdurrazaq Abdurrazaq Abdurrazaq, Abdurrazaq Ahmad Ahmad Ridha Akbar, Depy Oktavian Alista, Siti Ari Surya Pratama Aristha Novyra Putri Astuti, Karunita Ika Ayunda, Feradella Azmi Yunarti Azwarina Nuke Bella Rosalina Endah Bin Jamaludin, Wahyudin Chandra, M. Andi Depy Oktavian Akbar Didik Rio Pambudi Dyera Forestryana Eka Sandra Era Habibah Faradilla Iedliany Gunawan Gunawan Gusti Khairunnisa Hadirvika Tjuthiyanda Hafiz Ramadhan Hafiz Ramadhan hairunnisa nisa Helmina Wati Hidayati Rahmi Iedliany, Faradilla Jamaludin, Wahyudin Bin Karunika Ika Astuti Khairunnisa, Gusti Liana Fitriani Hasyim Liana Fitriani Hasymi M. Andi Chandra M. Fahrul Ricky NorHavid Malik Yustika Marlia Fatwa Muammaroh Muhammad Hafizudin Muhammad Hidayattullah Muhammad Nazarudin Muhammad Nazarudin, Muhammad Muhammad Nur Rahman Hendrawan Muhammad Reza Fahlevi Muhammad Saufi Murniati . Nashrul Wathan Noor Hayati, Noor Nopita Norhasanah Norhasanah Novita Sari Nur Huda Nurbidayah Nurul Hikmah Nurul Mardiati Putri Indah Sayakti Putri Kartika Sari Putri Kartika Sari Rahmayanti Fitriah Rahmi Muthia Ratna Restapaty Rina Helmina Riwanda Oktaviani Rizka D.A. Widianti Rusida, Esty Restiana Saputri, Revita Sari Wahyunita Setyo Yogi Shelin Shelin Siti Kholilah Siti Kholilah Susiani, Eka Fitri Syaid Nofal Assegaf Syamratul Qalbiyah Syifa Tia Mariati Risma Melati Vebruati Vebruati Vebruati Vebruati Wahyudin Bin Jamalludin Wahyudin Bin Jamaludin Yuni Fahriana Yusmalina Yusmalina Yusrina Conitaty Zannah, Meryatul