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All Journal Jurnal Ilmiah Farmasi MPI (Media Pharmaceutica Indonesiana) Pharmascience Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Jurnal Ilmiah Manuntung SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Kreativitas PKM JCPS (Journal of Current Pharmaceutical Sciences) Pharmacoscript Lumbung Farmasi : Jurnal Ilmu Kefarmasian Borneo Journal Of Pharmascientech SPIN: Jurnal Kimia & Pendidikan Kimia Jurnal Mandala Pengabdian Masyarakat Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Indonesian Community Journal Journal Borneo Jurnal Bakti Untuk Negeri Literasi: Jurnal Pengabdian Masyarakat dan Inovasi Sains Medisina Jurnal Penelitian dan Kajian Ilmiah Kesehatan Politeknik Medica Farma Husada Mataram Parapemikir Jurnal Ilmiah Farmasi Jurnal Farmasi dan Farmakoinformatika Borneo Journal of Pharmacy Jurnal Sains dan Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Fitriyanti, Fitriyanti
Fakultas Farmasi, Universitas Borneo Lestari, Banjarbaru, Kalimantan Selatan, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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FORMULASI GEL EKSTRAK METANOL DAUN BALIK ANGIN (Alphitonia incana (Roxb.) Teijsm. & Binn. Ex Kurz): Bahasa Indonesia Hafiz Ramadhan; Rina Helmina; Yuni Fahriana; Rahmi Muthia; Fitriyanti; Dyera Forestryana
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 11 No. 2 (2024)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v11i2.9863

Abstract

Daun Balik Angin (Alphitonia incana (Roxb.) Teijsm. & Binn. Ex Kurz) yang dimaserasi dengan metanol dapat menghambat pertumbuhan S. aureus dan S. epidermidis dengan kadar hambat minimum (KHM) 927 μg/mL dan 1428 μg/mL. Ekstrak daun yang diekstraksi dengan Soxhlet memiliki aktivitas antioksidan yang sangat kuat (IC50 32 μg/ml), sehingga ekstrak tersebut dapat dikembangkan menjadi sediaan topikal. Penelitian ini bertujuan untuk mengetahui formula terbaik berdasarkan karakteristik dan stabilitas (Freeze-thaw cycling) sediaan gel ekstrak metanol daun balik angin. Daun balik angin diekstraksi menggunakan metode maserasi dan soxhlet dengan pelarut metanol, dan dibuat menjadi sediaan gel menggunakan variasi konsentrasi karbopol yaitu 0,5% (F1), 0,75% (F2), dan 1% (F3). Evaluasi sediaan meliputi uji organoleptis, homogenitas, daya sebar, daya lekat, pH, viskositas, dan hedonik. Hasil karakteristik organoleptis berwarna kuning hingga coklat kekuningan, bau khas ekstrak, memiliki tekstur semi solid yang lembut dan homogen. Semua formula memenuhi persyaratan evaluasi fisik sediaan topikal selama siklus pengujian freeze-thaw. Berdasarkan evaluasi fisik, siklus pengujian freeze-thaw, dan uji hedonik dapat disimpulkan bahwa didapatkan formula terbaik dengan konsentrasi Karbopol 0,75% pada ekstrak hasil soxhlet dan formula terbaik dari ekstrak hasil maserasi pada konsentrasi karbopol 0,5%.
UJI EFEKTIVITAS ANTIBAKTERI ESKTRAK ETIL ASETAT BAWANG DAYAK (Eleutherine palmifolia Merr) TERHADAP STAPHYLOCOCCUS AUREUS DENGAN METODE SUMURAN Fitriyanti Fitriyanti; Abdurrazaq Abdurrazaq; Muhammad Nazarudin
Jurnal Ilmiah Manuntung Vol 5 No 2 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i2.278

Abstract

Dayak onion (Eleutherine palmifolia Merr.) is a multifunctional medicinal plant for various diseases, one of which is an antibacterial. Dayak Onions (E. palmifolia Merr.) contains an alkaloid, flavonoid, triterpenoid, and saponin compound which has antibacterial properties. This study aims to determine the effect of the ethyl acetate extract of Dayak Onion tubers inhibits the growth of Staphylococcus aureus bacteria. Dayak onion tuber was extracted using ethyl acetate solvent by the maceration method until thick extract was obtained. The concentration extract used were 30 mg/ml;15 mg/ml;7,5 mg/ml;3,75 mg/ml; 1,875 mg/ml; and 0,9375 mg/ml tested for antibacterial effectivity against Staphylococcus aureus using Mueller Hinton Agar (MHA) with the wells method. The result showed that the ethyl acetate of Dayak onion with MEC (Minimum effective concentration) 3,75 mg/ml obtained inhibition zone of 10,367 mm while at the highest concentration of 30 mg/ml had the best antibacterial effectiveness. The effective concentration of ethyl acetate onion of Dayak tuber which is 30 mg/ml obtained inhibition zone of 18,404 mm even in the moderate category.
PENGARUH METODE EKSTRAKSI TERHADAP AKTIVITAS ANTIBAKTERI DAUN RAMANIA (Bouea macrophylla Griffith) TERHADAP Staphylococcus aureus Fitriyanti; Syifa; Ahmad; Revita Saputri; Rahmi Muthia
Pharmacoscript Vol. 7 No. 1 (2024): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v7i1.1462

Abstract

Ekstrak metanol dari daun Ramania (Bouea macrophylla Griffith) telah teruji dengan dosis kecil memiliki efek antibakteri terhadap bakteri Staphylococcus aureus, namun belum pernah dilakukan pengujian pada dosis yang lebih tinggi dan membandingkan pada metode ekstraksi yang berbeda seperti maserasi dan soxhletasi. Pada penelitian bermaksud untuk mengetahui golongan senyawa yang terdapat pada ekstrak metanol dari daun ramania dengan metode yang berbeda dan untuk mengetahui pengaruh peningkatan konsentrasi ekstrak terhadap penghambatan bakteri S.aureus dengan penyarian secara maserasi dan soxhletasi. Uji antibakteri dilakukan menggunakan metode difusi sumuran. Penapisan fitokimia terhadap ektrak metanol daun remania menunjukkan keberadaan senyawa yaitu mengandung senyawa saponin, flavonoid, fenol, tanin, steroid. Hasil ují antibakteri terhadap ekstrak daun ramania yang diperoleh dengan metode maserasi lebih baik dibandingkan dengan ekstrak yang diperoleh dengan metode Soxlet, yaitu pada konsentrasi 50, 40, 30, 20 dan 10%, memberikan zona hambat berturut-turut sebesar 19,28;13,28; 12,93; 12,25; dan 10,98 mm, dengan kategori kuat. Sedangkan hasil pada pengujian dengan esktraksi menggunakan alat soxhlet pada konsentrasi 50, 40, 30, 20 dan 10%, memberikan zona hambat berturut-turut sebesar 10,7; 10,3; 8,9; 8,6; dan  8,3 mm dengan kategori sedang sampai kuat.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK METANOL DAUN RAMANIA (Bouea macrophylla Griffith) TERHADAP BAKTERI Staphylococcus epidermidis Murniati, Murniati; Fitriyanti, Fitriyanti; Jamaludin, Wahyudin Bin
Parapemikir : Jurnal Ilmiah Farmasi Vol 13, No 1 (2024): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v13i1.5786

Abstract

Daun ramania (B. Macrophylla Griffith) memiliki banyak manfaat dalam bidang kesehatan. Salah satu pemanfaatan sebagai tumbuhan obat yaitu dapat berefek sebagai antibakteri. Tujuan dari penelitian ini adalah untuk mengetahui senyawa metabolit sekunder yang terkandung di dalam ekstrak metanol daun Ramania (B.macrophylla Griffith) dan untuk mengetahui aktivitas antibakteri ekstrak metanol daun ramania (B. macrophylla Griffith) dalam menghambat pertumbuhan bakteri S. epidermidis. Uji aktivitas antibakteri ekstrak dilakukan dengan metode difusi sumuran terhadap bakteri S. epidermidis dengan 5 konsentrasi yaitu konsentrasi 10%, 20%, 30%, 40% dan 50%. Kontrol positif Klindamisin 2µg/disk dan kontrol negatif Na-CMC 0,5%. Hasil skrining fitokimia ekstrak metanol daun Ramania (B. macrophylla Griffith) mengandung flavonoid, tanin, saponin, steroid, dan fenol. Hasil uji aktivitas antibakteri ekstrak metanol  daun ramania (B. macrophylla Griffith) memperoleh nilai rata-rata diameter zona hambat dari konsentrasi 10% yaitu 9,875 dengan kategori sedang, pada konsentrasi 20%, 30%, 40%, dan 50% yaitu memiliki nilai masing-masing 11,338 mm; 13,44 mm; 16,025 mm; 16,4 mm dengan kategori kuat. Sedangkan pada kontrol positif Klindamisin 2 µg/disk yaitu 24,55 mm dengan kategori sangat kuat dan kontrol negatif Na-CMC 0,5% tidak memiliki daya hambat. Berdasarkan hasil yang diperoleh, dapat disimpulkan bahwa ekstrak metanol daun ramania (B. Macrophylla Griffith) mempunyai kemampuan sebagai antibakteri dalam kategori sedang, kuat, sampai sangat kuat dalam menghambat bakteri S. epidermidis.
Sosialisasi Sertifikasi Halal Sebagai Edukasi Bagi Pelaku UMKM di Kecamatan Martapura Barat Iedliany, Faradilla; Fitriyanti, Fitriyanti; Nurbidayah, Nurbidayah; Akbar, Depy Oktavian; Khairunnisa, Gusti
I-Com: Indonesian Community Journal Vol 5 No 2 (2025): I-Com: Indonesian Community Journal (Juni 2025)
Publisher : Fakultas Sains Dan Teknologi, Universitas Raden Rahmat Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70609/icom.v5i2.7041

Abstract

Micro, Small and Medium Enterprises (MSMEs) participate in Indonesia's economic conditions, but most MSME actors still do not add halal labels to their production. This is due to the lack of literacy about halal certification. This Community Service activity aims to educate and socialize the process and benefits of halal certification for MSME actors in Sungai Rangas Village and Banteng Ulu Mobile Village, West Martapura District, Banjar Regency. The method of this activity is first, the delivery of socialization materials, video tutorial playbacks, discussion and question and answer sessions, and filling out satisfaction survey questionnaires. The results of the activity showed that 80% of participants felt very satisfied and 20% were quite satisfied with the implementation of socialization activities. This shows that activities have a positive impact in providing insight into the importance of halal certification and as a strategy in developing a sustainable business.
PENGEMBANGAN MIKROEMULSI DARI EKSTRAK ETANOL 96% KULIT BATANG BALIK ANGIN (Alphitonia incana (Roxb.) Teijsm & Binn. Ex Kurz) Bin Jamaludin, Wahyudin; Muhammad Hidayattullah; Muammaroh; Fitriyanti; Marlia Fatwa
Jurnal Ilmiah Manuntung Vol 11 No 1 (2025): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v11i1.881

Abstract

The 96% ethanol extract of Balik angin stem bark contains secondary metabolite compounds that have potential antioxidant activity with a value of 37.00 ± 1.46µg/ml (bpj), the potential for use can be maximized in microemulsion preparations. In microemulsions, one of the ingredients that can affect the stability of the microemulsion is a cosurfactant which can affect the globule size and polydispersity index. Microemulsions were formulated by varying the type and concentration of cosurfactants to determine the optimal formula based on the test parameters of physical characteristics and stability of the preparation. The method used in this research is experimental and in the manufacture of microemulsions, namely the spontaneous emulsification method. The test results show that all formulas in the organoleptic test are clear except F1, the Tyndall test can transmit light, the pH value is 5.4 -5.6, the microemulsion type is M/A, the specific gravity is 1.038-1.064, the viscosity value is less than 200 cPs and the percent transmittance obtained ranges from 90-97%. The globule size test of F2 to F6 (55.03-1045) and the polydispersity index test of F2 to F6 (0.277-0.827), but the results were not detected in F1. The results of statistical tests on pH and specific gravity tests obtained p-value (>0.05), F3 viscosity test obtained p-value (<0.05) and T% test on F1, F4, and F5 obtained p-value (<0.05) so it can be concluded that microemulsion preparations with variations in the type and concentration of cosurfactants have an influence on physical characteristics and stability, and the most optimal formula is F6.
Uji Aktivitas Antibakteri Ekstrak Etil Asetat Daun Tigaron (Crataeva nurvala Buch.Ham) Terhadap Bakteri Propionibacterium acnes Dengan Metode Difusi Sumuran Sari, Putri Kartika; Sari, Novita; Fitriyanti, Fitriyanti
BORNEO JOURNAL OF PHARMASCIENTECH Vol 9 No 1 (2025): Borneo Journal Of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59053/bjp.v9i1.559

Abstract

Tigaron (C. nurvala buch.Ham.) is a plant can be found in India, Africa, Australia, Japan, Myanmar, Sri Lanka, Malaysia, India and China. Traditionally, the bark, leaves, flowers and root are used in traditional medicine to cure various disease conditions. The leaves of this plant used to treat abscesses, wounds and skin diseases. This study aims to determine of secondary metabolite and antibacterial activity test from ethyl acetate extract of tigaron leaves (C. nurvala buch.Ham.) in inhibiting growth of Propionibacterium acnes with varying concentration which are 0.31 mg/ml, 1.55 mg/ml, 7.75 mg/ml, 38.75 mg/ml, 193.75 mg/ml, negative control Na-CMC 0, 5% and positive control antibiotic clindamycin. Tigaron leaves were extracted using the maceration method using ethyl acetate solvent, secondary metabolite compounds detected using phytochemical screening method and antibacterial activity test using the well diffusion method. The final yield of ethyl acetate extract of tigaron leaves (C. nurvala buch. Ham.) was obtained at 1%. The secondary metabolite contained are alkaloids, flavonoids and steroids. The results showed that concentration of 0.31 mg/mL was included in the weak category inhibition zone (4.97 mm), 1.55 mg/mL (5.97 mm), 7.75 mg/mL (7.08 mm), 38.75 mg/mL (10.02 mm) which was included in the medium category inhibition zone and concentration of 193.75 mg/mL which is included in the strong category inhibition zone, clindamycin antibiotic as a positive control showed a strong zone of inhibition (16.5 mm). Ethyl acetate extract of tigaron leaves (C. nurvala buch.Ham.) can inhibit the growth of Propionibacterium acnes.
Co-Authors Abdurrazaq Abdurrazaq Abdurrazaq Abdurrazaq, Abdurrazaq Ahmad Ahmad Ridha Akbar, Depy Oktavian Alista, Siti Aprillia Rahmadina Ari Surya Pratama Aristha Novyra Putri Astuti, Karunita Ika Ayunda, Feradella Azmi Yunarti Azwarina Nuke Bella Rosalina Endah Bin Jamaludin, Wahyudin Chandra, M. Andi Cindy Pasaribu Depy Oktavian Akbar Depy Oktavian Akbar Didik Rio Pambudi Dyera Forestryana Eka Sandra Era Habibah Faradilla Iedliany Faradilla Iedliany Gunawan Gunawan Gusti Khairunnisa Gusti Khairunnisa Gusti Rizaldi Gustii Khairunnisa Hadirvika Tjuthiyanda Hafiz Ramadhan Hafiz Ramadhan hairunnisa nisa Helmina Wati Hidayati Rahmi Iedliany, Faradilla Jamaludin, Wahyudin Bin Karunika Ika Astuti Khairunnisa, Gusti Liana Fitriani Hasyim Liana Fitriani Hasymi M. Andi Chandra M. Fahrul Ricky NorHavid Malik Yustika Marlia Fatwa Muammaroh Muhammad Hafizudin Muhammad Hidayattullah Muhammad Nazarudin Muhammad Nazarudin, Muhammad Muhammad Nur Rahman Hendrawan Muhammad Reza Fahlevi Muhammad Saufi Muhammad Sauqi Murniati . Nashrul Wathan Noor Hayati, Noor Nopita Norhasanah Norhasanah Novita Sari Nur Huda Nurbidayah Nurul Hikmah Nurul Mardiati Putri Indah Sayakti Putri Kartika Sari Putri Kartika Sari Rahmayanti Fitriah Rahmi Muthia Ratna Restapaty Rina Helmina Riwanda Oktaviani Rizka D.A. Widianti Rusida, Esty Restiana Saputri, Revita Sari Wahyunita Setyo Yogi Shelin Shelin Siti Kholilah Siti Kholilah Susiani, Eka Fitri Syaid Nofal Assegaf Syamratul Qalbiyah Syifa Tania Nasyawa Azzahra Tia Mariati Risma Melati Vebruati Vebruati Vebruati Vebruati Wahyudin Bin Jamalludin Wahyudin Bin Jamaludin Wahyudin Bin Jamaludin Yuni Fahriana Yusmalina Yusmalina Yusrina Conitaty Zannah, Meryatul