Article Per Year (5 Year)
p-Index From 2021 - 2026
4.79
P-Index
This Author published in this journals
All Journal Pharmasipha SCIENTIA JOURNAL Jambura Journal of Health Sciences and Research Jurnal Kesmas dan Gizi (JKG) JURNAL FARMASIMED (JFM) Jurnal Dunia Farmasi Jurnal Prima Medika Sains Jurnal Kesehatan Tambusai PRIMER (Prima Medical Journal) Buletin Kedokteran dan Kesehatan Prima Jurnal Pengmas Kestra (JPK)
Reh Malem br Karo
Program Studi Farmasi Klinis, Fakultas Kedokteran, Kedokteran Gigi Dan Ilmu Kesehatan Universitas Prima Indonesia Medan, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 31 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 31 Documents
Search

 1   2   3   4 
Determination of Flavonoid Courtesy and Antibactery Test of Propionibacterium Acne in Facial Wash Medications Containing The Leaf Extract of (Drymoglossum Piloselloides L.) Jhon Patar Sinurat; Annisah Rivina Mardiyyah; Reh Malem Br Karo; Wira Maria Ginting; Yurizki Telova
Jurnal FARMASIMED (JFM) Vol 9 No 1 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v9i1.4088

Abstract

Acne vulgaris remains one of the most common skin conditions. Propionibacterium acnes, a Gram-positive bacterium that forms part of the normal skin microbiota, can contribute to acne development. Dragon scale leaves contain antibacterial compounds capable of inhibiting the growth of and killing pathogenic microorganisms. Their flavonoid content and associated antibacterial activity support their use as an ingredient in anti-acne preparations. This study aimed to determine the flavonoid content of dragon scale leaves (Drymoglossum piloselloides L.), evaluate the quality of facial cleanser formulations using the specified test parameters, and assess the antibacterial activity of the leaf extract against P. acnes. The leaves were extracted by maceration using 96% ethanol, and the resulting extract was qualitatively screened for flavonoids. Flavonoid content was determined using ultraviolet–visible (UV–Vis) spectrophotometry with quercetin as the reference standard. The facial cleanser formulations were evaluated for stability using the specified test parameters, and antibacterial activity against P. acnes was assessed. Extraction with 96% ethanol yielded 18.62%. The flavonoid content, determined at a maximum absorbance wavelength of 433 nm, was 23.97%. All three tested concentrations exhibited strong antibacterial activity, with mean inhibition zone diameters ranging from 18.33 to 20.33 mm. These findings demonstrate that dragon scale leaf extract containing flavonoids exhibits antibacterial activity against P. acnes.
Co-Authors Afri Abdiansyah Afri Abdiansyah Andri Hidayat, Andri Annisah Rivina Mardiyyah Asyrun Alkhairi Lubis Ayuningsari, Laras Br Sihite, Rani Marselina Br Turnip, Nur Ulina M. Cahya, Cucu Arum Dwi Christine, Yesina Duha, Kristin Berlianta Elfia Neswita Erida Novriani etha tesalonika tamba Fadillah, Qori Fibrini, Dewi Fioni, Fioni Ginting, Wira Maria Harahap, Rahmat Ali Putra Hoswari, Cindy Natasya Husna, Miftahul Khairunnisa Batubara Lina, Juliana Manao, Merlianasari Meutia, Rena Nasution, Ali Napiah Natali, Oliviti Neswita, Elfia Novandi Purba purba, marina novelly br Razoki Razoki Razoki, Razoki Regina Elianda Tampubolon Sembiring, Novitaria Br. Shofian Syarifuddin Simanjuntak, Nerly Juli Pranita Sinurat, Jhon Patar Sirait, Reni Aprinawaty Sri Lestari Ramadhani Nasution Suci Wulandari Syarifuddin, Aminah Nur Syarifuddin, Shofian Tanamal, Claudia Telova, Yurizki Theresia, Yohani Wardah Fitria Tanjung Wardah Fitria Tanjung Windi Wildani Windi Wildani Wira Maria Ginting Yanti, Dian Anggri Yohana Silvia Uli Manalu Yudha, M Yurizki Telova Zahara Fitria